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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2009, Volume 106, Issue 12, pp. 4793 - 4798
Journal Article
Immunity, ISSN 1074-7613, 2008, Volume 28, Issue 6, pp. 870 - 880
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 34, pp. 15181 - 15186
Toll-like receptor 9 (TLR9) senses microbial DNA and triggers type I IFN responses in plasmacytoid dendritic cells (pDCs). Previous studies suggest the... 
RNA | Dendritic cells | DNA | Cell lines | Antivirals | Antibodies | Small interfering RNA | Innate immunity | Cellular immunity | Sensors | Cytosolic sensor | VIRUS | RECOGNITION | MULTIDISCIPLINARY SCIENCES | INNATE IMMUNE-RESPONSE | CYTOSOLIC DNA | ALPHA | INDUCTION | cytosolic sensor | innate immunity | PATHWAY | INFECTION | ADAPTER PROTEIN | RNA, Small Interfering - genetics | Dendritic Cells - immunology | Humans | Neoplasm Proteins - antagonists & inhibitors | Phylogeny | Neoplasm Proteins - metabolism | DEAD-box RNA Helicases - antagonists & inhibitors | Base Sequence | B-Lymphocytes - virology | DEAD-box RNA Helicases - metabolism | Dendritic Cells - virology | Neoplasm Proteins - genetics | Binding Sites | DEAD-box RNA Helicases - chemistry | B-Lymphocytes - metabolism | Dendritic Cells - metabolism | Protein Structure, Tertiary | Cell Line | NF-kappa B p50 Subunit - metabolism | Signal Transduction | DNA, Viral - metabolism | Neoplasm Proteins - chemistry | Immunity, Innate | Interferon Regulatory Factor-7 - metabolism | Receptors, Transferrin - metabolism | DEAD-box RNA Helicases - genetics | B-Lymphocytes - immunology | CpG Islands | Myeloid Differentiation Factor 88 - metabolism | Natural immunity | Genetic aspects | Research | Biological response modifiers | Properties | Binding proteins | Human immunogenetics | Phosphates | Amino acids | Cytokines | Ribonucleic acid--RNA | Neurons | Deoxyribonucleic acid--DNA | Biological Sciences
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 14, pp. 3894 - 3907
Oncolytic viruses selectively lyse tumor cells, disrupt immunosuppression within the tumor, and reactivate antitumor immunity, but they have yet to live up to... 
OX40 | VIRUS | COLONY-STIMULATING FACTOR | EFFICACY | ONCOLOGY | B7-H1 EXPRESSION | GLIOMA | ANTIBODY | CHECKPOINTS | OX40 Ligand - genetics | Cancer Vaccines - pharmacology | Humans | OX40 Ligand - biosynthesis | Neoplasms - virology | Neoplasms - therapy | Melanoma, Experimental - immunology | Glioma - therapy | HEK293 Cells | Melanoma, Experimental - virology | A549 Cells | Immunomodulation | Melanoma, Experimental - therapy | Mice, Inbred C57BL | Glioma - immunology | Oncolytic Viruses - genetics | Lung Neoplasms - therapy | Lung Neoplasms - virology | B7-H1 Antigen - immunology | Oncolytic Virotherapy - methods | Lung Neoplasms - immunology | Animals | B7-H1 Antigen - antagonists & inhibitors | OX40 Ligand - immunology | Mice, Nude | Neoplasms - immunology | Oncolytic Viruses - immunology | Oncolytic Viruses - physiology | Cell Line, Tumor | Mice | CD8-Positive T-Lymphocytes - immunology | Glioma - virology | Cell proliferation | Therapy | Toxicity | CD8 antigen | Vaccination | Viruses | Activation | Lymphocytes T | Immunity | Modulators | Recruitment | Cell activation | Lymphocytes | Oncolysis | Antigens | Immunological memory | Effectiveness | Tumor cells | Immunodeficiency | Costimulator | Immunosuppression | Ox40L protein | Immune checkpoint | Immunogenicity | Tumor necrosis factor | Cell death | Antigen (tumor-associated) | PD-L1 protein | Ligands | Cancer | Apoptosis | Index Medicus | PD-L1 | oncolytic adenovirus | Delta-24-RGDOX | OX40L | Delta-24-RGD
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2018, Volume 24, Issue 5, pp. 1114 - 1123
Purpose: mAbs such as anti-CD20 rituximab are proven therapies in B-cell malignancies, yet many patients develop resistance. Novel therapies against... 
THERAPY | IBRUTINIB RESISTANCE | ONCOLOGY | ANTI-BR3 ANTIBODIES | RITUXIMAB | DISEASE | NON-HODGKIN-LYMPHOMA | MONOCLONAL-ANTIBODY | LOW-GRADE | LEUKEMIA | EXPRESSION | Lymphoma, B-Cell - blood | Humans | Antibody-Dependent Cell Cytotoxicity - immunology | Antibodies, Monoclonal - therapeutic use | B-Cell Activation Factor Receptor - antagonists & inhibitors | Inhibitory Concentration 50 | B-Cell Activation Factor Receptor - genetics | Antibodies, Monoclonal - immunology | B-Cell Activation Factor Receptor - immunology | Lymphoma, B-Cell - drug therapy | Antibodies, Monoclonal - pharmacology | Drug Resistance, Neoplasm - immunology | Recombinant Proteins - genetics | Protein Folding | Antineoplastic Agents, Immunological - pharmacology | Xenograft Model Antitumor Assays | Animals | Recombinant Proteins - immunology | Antineoplastic Agents, Immunological - therapeutic use | Hybridomas | Lymphoma, B-Cell - pathology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Antibody-Dependent Cell Cytotoxicity - drug effects | Drug Resistance, Neoplasm - drug effects | Therapy | Animal models | Immunoglobulins | Toxicity | Leukemia | Immunodeficiency | Antibodies | Rituximab | Cytotoxicity | Drug resistance | Patients | Cell surface | Lymphoma | Anticancer properties | Lymphocytes B | Experimental design | BLyS protein | Cell lines | CD20 antigen | Antitumor activity | Biocompatibility | Tumors | Cancer | Recombinant
Journal Article
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 07/2019
Recent studies demonstrate the role of the tumor microenvironment in tumor progression. However, strategies used to overcome the malignant phenotypes of cancer... 
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 12/2014, Volume 135, Issue 12, pp. 2834 - 2846
Journal Article
Journal Article