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Science, ISSN 0036-8075, 5/2012, Volume 336, Issue 6082, pp. 717 - 721
Osteoarthritis (OA) is a degenerative joint disease that involves the destruction of articular cartilage and eventually leads to disability. Molecules that... 
Cartilage | Molecules | REPORTS | Chondrocytes | Collagens | Stem cells | Lead | Arthritis | Chondrogenesis | Osteoarthritis | Vehicles | PATHOGENESIS | GENE | ARTICULAR-CARTILAGE | MULTIDISCIPLINARY SCIENCES | FILAMIN | OSTEOARTHRITIS | BONE | TRANSCRIPTION FACTOR | EXPRESSION | CHONDROGENESIS | CHONDROCYTE DIFFERENTIATION | Anilides - therapeutic use | Chondrocytes - cytology | Phthalic Acids - chemistry | Humans | Anilides - chemistry | Structure-Activity Relationship | Osteoarthritis - drug therapy | Osteoarthritis - physiopathology | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Cell Nucleus - metabolism | Chondrocytes - physiology | Cattle | Microfilament Proteins - metabolism | Osteoarthritis - pathology | Phthalic Acids - pharmacology | Contractile Proteins - metabolism | Chondrocytes - metabolism | Mesenchymal Stromal Cells - physiology | Core Binding Factor beta Subunit - metabolism | Disease Models, Animal | Mesenchymal Stromal Cells - drug effects | Phthalic Acids - therapeutic use | Core Binding Factor Alpha 2 Subunit - metabolism | Cartilage, Articular - cytology | Filamins | Phthalic Acids - administration & dosage | Regeneration | Animals | High-Throughput Screening Assays | Anilides - administration & dosage | Small Molecule Libraries | Anilides - pharmacology | Mice | Care and treatment | Physiological aspects | Transplantation | Methods | Molecular biology | Index Medicus | Animal models | Biomedical materials | Effectiveness | Breakdown | Biocompatibility | Articular | Adults
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2009, Volume 106, Issue 22, pp. 8912 - 8917
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5997, pp. 1345 - 1348
Although practiced clinically for more than 40 years, the use of hematopoietic stem cell (HSC) transplants remains limited by the ability to expand these cells... 
Hep G2 cells | Cytokines | REPORTS | Stem cells | Multipotent stem cells | Bone marrow | Cultured cells | Transplantation | Aryl hydrocarbon receptors | Hematopoietic stem cells | Blood | EX-VIVO EXPANSION | ENGRAFTMENT | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | BIOLOGY | MICE | UMBILICAL-CORD BLOOD | BINDING | TRANSPLANTATION | Antigens, CD34 - analysis | Cell Proliferation | Receptors, Aryl Hydrocarbon - antagonists & inhibitors | Species Specificity | Cell Count | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Antigens, CD - analysis | Multipotent Stem Cells - drug effects | Hematopoiesis | Polychlorinated Dibenzodioxins - pharmacology | Hematopoietic Stem Cells - physiology | Receptors, Aryl Hydrocarbon - metabolism | Multipotent Stem Cells - physiology | Hematopoietic Stem Cells - drug effects | Signal Transduction | Purines - metabolism | Purines - pharmacology | Cells, Cultured | Hematopoietic Stem Cell Transplantation | Hematopoietic Stem Cells - metabolism | Mice, SCID | AC133 Antigen | Aryl Hydrocarbon Hydroxylases - metabolism | Cell Lineage | Animals | Multipotent Stem Cells - cytology | Small Molecule Libraries | Hematopoietic Stem Cells - cytology | Cytochrome P-450 CYP1B1 | Mice, Inbred NOD | Mice | Glycoproteins - analysis | Cytokines - pharmacology | Peptides - analysis | Physiological aspects | Arylation | Human | Receptors | Aromatic compounds | Modulation | Hydrocarbons | Derivatives | Culture | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, pp. e40976 - e40976
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, pp. e31226 - e31226
Journal Article
Current Organic Chemistry, ISSN 1385-2728, 10/2016, Volume 20, Issue 22, pp. 2358 - 2378
Journal Article
Journal Article
Organic Letters, ISSN 1523-7060, 03/2005, Volume 7, Issue 5, pp. 897 - 900
Efficient methods for the stereoselective synthesis of polyfunctional (E)- and (2)-alkenes and conjugated (EE)- and (E,2)-dienones are presented. They rely... 
BOND-FORMING REACTION | METHYL SULFONES | 4-COMPONENT SYNTHESIS | ONE-POT | CHEMISTRY, ORGANIC | CARBONYL-COMPOUNDS | STEREOSELECTIVE-SYNTHESIS
Journal Article
CHEMISTRY-A EUROPEAN JOURNAL, ISSN 0947-6539, 2006, Volume 12, Issue 2, pp. 349 - 349
Journal Article
Journal Article
Synlett, ISSN 0936-5214, 06/2017, Volume 28, Issue 10, pp. 1219 - 1223
Abstract β-(2-Pyridyl) ketones are a unique class of heterocycles with valuable physicochemical properties and emerging relevance as pharmacophores. Herein we... 
letter | β-(2-pyridyl) propanone | malaria | acylation | small-molecule natural-product analogues | beta-(2-pyridyl) propanone | BASES | DRUG DISCOVERY | CHEMISTRY, ORGANIC | HARD | CYCLIZATIONS | CHEMISTRY | SOFT ACIDS | CLADOSPORIN | METABOLITE | TOOL
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 12/2018, Volume 13, Issue 12, pp. 3354 - 3360
Hypoxia, a condition of reduced oxygen, occurs in a wide variety of biological contexts, including solid tumors and bacterial biofilms, which are relevant to... 
CELLS | DESIGN | PROTEIN | TUMOR HYPOXIA | PRODRUGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPRESSOR SYSTEM
Journal Article
Journal Article