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1. Full Text Role of muscle mass and muscle quality in the association between diabetes and gait speed
by Volpato, Stefano and Bianchi, Lara and Lauretani, Fulvio and Lauretani, Fabrizio and Bandinelli, Stefania and Guralnik, Jack M and Zuliani, Giovanni and Ferrucci, Luigi
Diabetes Care, ISSN 0149-5992, 08/2012, Volume 35, Issue 8, pp. 1672 - 1679
OBJECTIVE-Older people with type 2 diabetes are at high risk of mobility disability. We investigated the association of diabetes with lower-limb muscle mass... 
INCHIANTI | SKELETAL-MUSCLE | PHYSICAL PERFORMANCE BATTERY | OLDER-ADULTS | SUBSEQUENT DISABILITY | ENDOCRINOLOGY & METABOLISM | BODY-COMPOSITION | PERIPHERAL ARTERIAL-DISEASE | GLUCOSE-TOLERANCE | WOMENS HEALTH | LOWER-EXTREMITY DISABILITY | Diabetes Mellitus, Type 2 - physiopathology | Cross-Sectional Studies | Humans | Aged, 80 and over | Female | Male | Aged | Muscle, Skeletal - physiology | Gait - physiology | Muscle Strength - physiology | Type 2 diabetes | Walking | Diabetics | Analysis | Aging | Muscular system | Diabetes | Womens health | Older people | Index Medicus | Original Research
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2. Full Text Skeletal Muscle and Mortality Results From the InCHIANTI Study
by Cesari, Matteo and Pahor, Marco and Lauretani, Fulvio and Zamboni, Valentina and Bandinelli, Stefania and Bernabei, Roberto and Guralnik, Jack M and Ferrucci, Luigi
Journals of Gerontology: Series A, ISSN 1079-5006, 3/2009, Volume 64A, Issue 3, pp. 377 - 384
Background Sarcopenia, the age-related loss of muscle mass, may not be an isolated process but is associated with an increase in fat mass. The aim of this... 
Obesity | Sarcopenia | Mortality | InCHIANTI | Fat mass | Walking speed | Body composition | Skeletal muscle | PHYSICAL PERFORMANCE | STRENGTH | LOWER-EXTREMITY FUNCTION | GERIATRICS & GERONTOLOGY | ELDERLY PERSONS | OLDER PERSONS | WOMEN | GERONTOLOGY | BODY-MASS INDEX | FUNCTIONAL DECLINE | GAIT SPEED | Confidence Intervals | Age Factors | Muscle Weakness - diagnosis | Humans | Muscle Weakness - epidemiology | Male | Muscle, Skeletal - metabolism | Physical Endurance - physiology | Walking - physiology | Sensitivity and Specificity | Inflammation Mediators - metabolism | Statistics, Nonparametric | Aged, 80 and over | Female | Obesity - diagnosis | Sarcolemma - metabolism | Body Mass Index | Enzyme-Linked Immunosorbent Assay | Comorbidity | Risk Factors | Proportional Hazards Models | Mortality - trends | Chi-Square Distribution | Aging - physiology | Muscle, Skeletal - physiopathology | Obesity - epidemiology | Geriatric Assessment - methods | Aged | Cohort Studies | Medical examination | Muscles | Italy | Development and progression | Health aspects | Risk factors | Studies | Tissue | Older people | Data collection | Age | Index Medicus | Abridged Index Medicus | Medical Sciences | Journal of Gerontology
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3. Full Text Sarcopenic obesity and inflammation in the InCHIANTI study
by Matthew A. Schrager and E. Jeffrey Metter and Eleanor Simonsick and Alessandro Ble and Stefania Bandinelli and Fulvio Lauretani and Luigi Ferrucci
Journal of Applied Physiology, ISSN 8750-7587, 03/2007, Volume 102, Issue 3, pp. 919 - 925
The aging process is often paralleled by decreases in muscle and increases in fat mass. At the extreme these two processes lead to a condition known as... 
Sarcopenia | Central obesity | Proinflammatory cytokines | C-REACTIVE PROTEIN | SPORT SCIENCES | proinflammatory cytokines | PHYSIOLOGY | central obesity | PHYSICAL PERFORMANCE | FACTOR-ALPHA | SKELETAL-MUSCLE | OLDER PERSONS | TUMOR-NECROSIS-FACTOR | MUSCLE STRENGTH | INSULIN-RESISTANCE | sarcopenia | GROWTH-FACTOR-I | ADIPOSE-TISSUE | Aging - blood | Body Mass Index | Humans | Aged, 80 and over | Muscle Weakness - blood | Female | Male | Aged | Biomarkers - blood | Obesity - blood | Inflammation - blood | Cytokines - blood | Aging | Obesity | Muscular system | Cytokines | Index Medicus
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4. Full Text Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia
by Fulvio Lauretani and Cosimo Roberto Russo and Stefania Bandinelli and Benedetta Bartali and Chiara Cavazzini and Angelo Di Iorio and Anna Maria Corsi and Taina Rantanen and Jack M. Guralnik and Luigi Ferrucci
Journal of Applied Physiology, ISSN 8750-7587, 11/2003, Volume 95, Issue 5, pp. 1851 - 1860
Sarcopenia, the reduction of muscle mass and strength that occurs with aging, is widely considered one of the major causes of disability in older persons.... 
Muscle power | Elderly | Strength | SPORT SCIENCES | PHYSIOLOGY | strength | elderly | PERFORMANCE | RELIABILITY | LOWER-EXTREMITY FUNCTION | PROTEIN-SYNTHESIS | GRIP STRENGTH | WOMEN | SUBSEQUENT DISABILITY | MASS | OLDER MEN | muscle power | EPIDEMIOLOGY | Torque | Age Distribution | Humans | Middle Aged | Muscular Atrophy - pathology | Male | Muscle, Skeletal - physiology | Aging - pathology | Walking | Muscular Atrophy - physiopathology | Aging - physiology | Muscle Contraction - physiology | Aged, 80 and over | Sex Distribution | Adult | Female | Aged | Muscle, Skeletal - pathology | Hand Strength | Muscular Atrophy - epidemiology | Aging | Skeletal system | Muscular system | Medical disorders | Index Medicus
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5. Full Text Activity Restriction Induced by Fear of Falling and Objective and Subjective Measures of Physical Function: A Prospective Cohort Study
by Deshpande, Nandini and Metter, E. Jeffrey and Lauretani, Fulvio and Bandinelli, Stefania and Guralnik, Jack and Ferrucci, Luigi
Journal of the American Geriatrics Society, ISSN 0002-8614, 04/2008, Volume 56, Issue 4, pp. 615 - 620
OBJECTIVES: To examine whether activity restriction specifically induced by fear of falling (FF) contributes to greater risk of disability and decline in... 
fear of falling | physical function | aging | activity restriction | disability | Disability | Aging | Fear of falling | Activity restriction | Physical function | INCHIANTI | AVOIDANCE | PERFORMANCE | FRAILTY | LOWER-EXTREMITY FUNCTION | PREVALENCE | GERIATRICS & GERONTOLOGY | ELDERLY PERSONS | LIVING OLDER-PEOPLE | COMMUNITY | SUBSEQUENT DISABILITY | GERONTOLOGY | Activities of Daily Living - psychology | Motor Activity - physiology | Prognosis | Prospective Studies | Cross-Sectional Studies | Follow-Up Studies | Risk Assessment | Humans | Accidental Falls - statistics & numerical data | Male | Mobility Limitation | Aged, 80 and over | Fear - psychology | Female | Italy | Aged | Falls | Lifestyles | Older people | Motor ability | Geriatrics | Index Medicus
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6. Full Text Low nutrient intake is an essential component of frailty in older persons
by Bartali, Benedetta and Frongillo, Edward A and Bandinelli, Stefania and Lauretani, Fulvio and Semba, Richard D and Fried, Linda P and Ferrucci, Luigi
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, ISSN 1079-5006, 2006, Volume 61, Issue 6, pp. 589 - 593
Background. Poor nutrient intake is conceptualized to be a component of frailty, but this hypothesis has been little investigated. We examined the association... 
INCHIANTI | MUSCLE | DISABILITY | GERONTOLOGY | AGE | DECLINE | GERIATRICS & GERONTOLOGY | Humans | Risk Factors | Male | Energy Intake | Incidence | Frail Elderly - statistics & numerical data | Aging - physiology | Malnutrition - prevention & control | Malnutrition - epidemiology | Female | Italy - epidemiology | Aged | Retrospective Studies | Dietary Supplements | Nutrition | Gerontology | Research | Aging | Older people | Index Medicus | Abridged Index Medicus
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7. Full Text Uric acid and inflammatory markers
by Ruggiero, Carmelinda and Cherubini, Antonio and Ble, Alessandro and Bos, Angelo J.G and Maggio, Marcello and Dixit, Vishwa D and Lauretani, Fulvio and Bandinelli, Stefania and Senin, Umberto and Ferrucci, Luigi
European Heart Journal, ISSN 0195-668X, 05/2006, Volume 27, Issue 10, pp. 1174 - 1181
The role of uric acid (UA) in the process of atherosclerosis and atherotrombosis is controversial. Epidemiological studies have recently shown that UA may be a... 
Inflammation | Metabolism | Comorbidity | Elderly | Uric Acid - metabolism | Cytokines - metabolism | Humans | Risk Factors | Neutrophils | Male | Biomarkers - blood | Leukocytes | Atherosclerosis - blood | Atherosclerosis - etiology | C-Reactive Protein - metabolism | Thrombosis - etiology | Aged, 80 and over | Female | Aged | Leukocyte Count | Thrombosis - blood | Index Medicus
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8. Full Text Absolute Strength and Loss of Strength as Predictors of Mobility Decline in Older Adults: The InCHIANTI Study
by Hicks, Gregory E and Shardell, Michelle and Alley, Dawn E and Miller, Ram R and Bandinelli, Stefania and Guralnik, Jack and Lauretani, Fulvio and Simonsick, Eleanor M and Ferrucci, Luigi
Journals of Gerontology:Series A: Biomedical Sciences and Medical Sciences, ISSN 1079-5006, 2012, Volume 67A, Issue 1, pp. 66 - 73
Background. Theoretical definitions of sarcopenia traditionally emphasize age-related loss of muscle strength; however, most analyses of the association... 
Sarcopenia | Strength | Mobility decline | MUSCULAR STRENGTH | MEANINGFUL CHANGE | PERFORMANCE | PHYSICAL-DISABILITY | RELIABILITY | GERIATRICS & GERONTOLOGY | WOMEN | MUSCLE STRENGTH | MASS | MEN | GERONTOLOGY | Geriatric Assessment | Knee - physiology | Humans | Male | Gait - physiology | Mobility Limitation | Sarcopenia - physiopathology | Muscle, Skeletal - physiopathology | Aged, 80 and over | Female | Aged | Hand Strength - physiology | Longitudinal Studies | Muscle Strength - physiology | Physiological aspects | Human mechanics | Muscle strength | Health aspects | Musculoskeletal diseases | Knee | Mobility | Older people | Risk factors | Index Medicus | Abridged Index Medicus | Journal of Gerontology | MEDICAL SCIENCES
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9. Full Text Use of the Short Physical Performance Battery Score to Predict Loss of Ability to Walk 400 Meters: Analysis From the InCHIANTI Study
by Vasunilashorn, Sarinnapha and Coppin, Antonia K and Patel, Kushang V and Lauretani, Fulvio and Ferrucci, Luigi and Bandinelli, Stefania and Guralnik, Jack M
Journals of Gerontology: Series A, ISSN 1079-5006, 2/2009, Volume 64A, Issue 2, pp. 223 - 229
Background Early detection of mobility limitations remains an important goal for preventing mobility disability. The purpose of this study was to examine the... 
Aging | Functional limitation | Mobility | Incidence of disability | 400 m walk | RISK-FACTORS | TAI-CHI | OLDER-ADULTS | MOBILITY LIMITATION | LOWER-EXTREMITY FUNCTION | EXERCISE | GERIATRICS & GERONTOLOGY | ELDERLY PERSONS | FUNCTIONAL MOBILITY | SUBSEQUENT DISABILITY | OBJECTIVE-MEASURE | GERONTOLOGY | Geriatric Assessment | Multivariate Analysis | Predictive Value of Tests | Confidence Intervals | Age Factors | Humans | Male | Sampling Studies | Walking - physiology | Activities of Daily Living | Mobility Limitation | Sensitivity and Specificity | Aged, 80 and over | Disabled Persons - statistics & numerical data | Female | Odds Ratio | Disability Evaluation | Risk Assessment | Logistic Models | Aging - physiology | Exercise Tolerance - physiology | Sex Factors | Italy | Aged | Postural Balance - physiology | Longitudinal Studies | Disability | Walking | Demographic aspects | Motor ability | Physiological aspects | Health aspects | Studies | Clinical trials | Older people | Index Medicus | Abridged Index Medicus | Medical Sciences | Journal of Gerontology
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10. Full Text The risk of dysphagia is associated with malnutrition and poor functional outcomes in a large population of outpatient older individuals
by Tagliaferri, Sara and Lauretani, Fulvio and Pelá, Giovanna and Meschi, Tiziana and Maggio, Marcello
Clinical Nutrition, ISSN 0261-5614, 2018
Oropharyngeal dysphagia (OD) is a widespread clinical condition among older adults. Although it represents a risk factor for malnutrition, dehydration and... 
Functional decline | EAT-10 | Elderly | MNA-SF | Physical frailty
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11. Full Text Molecular and clinical issues about the risk of venous thromboembolism in older patients: A focus on parkinson’s disease and parkinsonism
by Tana, Claudio and Lauretani, Fulvio and Ticinesi, Andrea and Prati, Beatrice and Nouvenne, Antonio and Meschi, Tiziana
International Journal of Molecular Sciences, ISSN 1661-6596, 05/2018, Volume 19, Issue 5, p. 1299
Venous thromboembolism (VTE) is a common and potentially life-threatening condition which includes both deep-vein thrombosis (DVT) and pulmonary embolism (PE).... 
Risk | Thromboembolism | Patients | Venous | Old | Frail | Elderly people | Basal ganglia | Parkinson's disease | Neurodegenerative diseases | Immobilization | Central nervous system diseases | Risk analysis | Thrombosis | Epidemiology | Embolism | Risk factors | Molecular chains | Health risk assessment | Movement disorders | Age | Geriatrics | venous | risk | frail | thromboembolism | old | patients
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12. Full Text Inflammatory Markers and Physical Performance in Older Persons: The InCHIANTI Study
by Cesari, Matteo and Penninx, Brenda W. J. H and Pahor, Marco and Lauretani, Fulvio and Corsi, Anna Maria and Williams, G. Rhys and Guralnik, Jack M and Ferrucci, Luigi
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, ISSN 1079-5006, 03/2004, Volume 59, Issue 3, pp. 242 - 248
Background. Some studies have proposed chronic inflammation as an underlying biological mechanism responsible for physical function decline in elderly people.... 
C-REACTIVE PROTEIN | SKELETAL-MUSCLE | TUMOR-NECROSIS-FACTOR | RISK-FACTORS | INTERLEUKIN-1 RECEPTOR ANTAGONIST | HEART-FAILURE | SERUM-LEVELS | GERONTOLOGY | BODY-COMPOSITION | CYTOKINE RECEPTORS | FACTOR-ALPHA | GERIATRICS & GERONTOLOGY | Prospective Studies | Humans | Risk Factors | Inflammation Mediators - blood | Aged, 80 and over | Aging | Female | Italy | Male | Physical Fitness | Aged | Biomarkers - blood | Disease | Health risk assessment | Medical disorders | Older people | Index Medicus | Abridged Index Medicus
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13. Full Text Frailty syndrome and skeletal muscle: Results from the Invecchiare in Chianti study
by Cesari, Matteo and Leeuwenburgh, Christiaan and Lauretani, Fulvio and Onder, Graziano and Bandinelli, Stefania and Maraldi, Cinzia and Guralnik, Jack M and Pahor, Marco and Ferrucci, Luigi
American Journal of Clinical Nutrition, ISSN 0002-9165, 05/2006, Volume 83, Issue 5, pp. 1142 - 1148
Background: Frailty is a common condition in elders and identifies a state of vulnerability for adverse health outcomes. Objective: Our objective was to... 
Aging | Frailty | Inflammation | Muscle density | Epidemiology | Fat mass | Body composition | Muscle mass | Skeletal muscle | muscle density | fat mass | SARCOPENIA | NECROSIS-FACTOR-ALPHA | STRENGTH | BODY-COMPOSITION | INTERLEUKIN-6 | muscle mass | frailty | epidemiology | OLDER PERSONS | WOMEN | body composition | NUTRITION & DIETETICS | inflammation | DISABILITY | aging | skeletal muscle | AGE | Body Composition | Body Mass Index | Humans | Fatigue | Logistic Models | Male | Tomography, X-Ray Computed | Frail Elderly | Muscle, Skeletal - physiology | Motor Activity | Walking | Weight Loss | Aged, 80 and over | Female | Italy | Aged | Health Status | Hand Strength | Muscle, Skeletal - anatomy & histology | Bones | Frail elderly | Health aspects | Density | Musculoskeletal system | Medical disorders | Index Medicus | Abridged Index Medicus
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