Seminars in Liver Disease, ISSN 0272-8087, 11/2012, Volume 32, Issue 4, pp. 271 - 272
Journal Article
Hepatology, ISSN 0270-9139, 01/2018, Volume 67, Issue 1, pp. 328 - 357
HEPATOCELLULAR-CARCINOMA HCC | ACTIVATED-RECEPTOR-ALPHA | VITAMIN-E | LONG-TERM OUTCOMES | MODERATE ALCOHOL-CONSUMPTION | BARIATRIC SURGERY | SEVERE MUSCLE DEPLETION | PLACEBO-CONTROLLED TRIAL | CORONARY-HEART-DISEASE | GASTROENTEROLOGY & HEPATOLOGY | INSULIN-SENSITIZING AGENTS | Liver Transplantation | Prevalence | Obesity - complications | Humans | Non-alcoholic Fatty Liver Disease - therapy | Incidence | Mass Screening | Adolescent | Non-alcoholic Fatty Liver Disease - diagnosis | Adult | Disease Management | Child | Non-alcoholic Fatty Liver Disease - epidemiology | Liver diseases | Fatty liver
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2010, Volume 362, Issue 18, pp. 1675 - 1685
In this randomized trial comparing vitamin E, pioglitazone, and placebo in adults without diabetes who had nonalcoholic steatohepatitis, vitamin E therapy was...
VARIABILITY | MEDICINE, GENERAL & INTERNAL | NAFLD | METAANALYSIS | STEATOSIS | FATTY LIVER-DISEASE | FOLLOW-UP | HISTORY | Hypoglycemic Agents - therapeutic use | Liver - pathology | Double-Blind Method | Fatty Liver - pathology | Fatty Liver - physiopathology | Humans | Middle Aged | Insulin Resistance | Male | Vitamin E - adverse effects | Chi-Square Distribution | Thiazolidinediones - adverse effects | Fatty Liver - drug therapy | Antioxidants - therapeutic use | Thiazolidinediones - therapeutic use | Intention to Treat Analysis | Vitamin E - therapeutic use | Adult | Antioxidants - adverse effects | Female | Transaminases - blood | Weight Gain - drug effects | Hypoglycemic Agents - adverse effects | Oxidative stress | Liver diseases | Drug therapy | Health aspects | Insulin resistance | Diabetes | Disease
VARIABILITY | MEDICINE, GENERAL & INTERNAL | NAFLD | METAANALYSIS | STEATOSIS | FATTY LIVER-DISEASE | FOLLOW-UP | HISTORY | Hypoglycemic Agents - therapeutic use | Liver - pathology | Double-Blind Method | Fatty Liver - pathology | Fatty Liver - physiopathology | Humans | Middle Aged | Insulin Resistance | Male | Vitamin E - adverse effects | Chi-Square Distribution | Thiazolidinediones - adverse effects | Fatty Liver - drug therapy | Antioxidants - therapeutic use | Thiazolidinediones - therapeutic use | Intention to Treat Analysis | Vitamin E - therapeutic use | Adult | Antioxidants - adverse effects | Female | Transaminases - blood | Weight Gain - drug effects | Hypoglycemic Agents - adverse effects | Oxidative stress | Liver diseases | Drug therapy | Health aspects | Insulin resistance | Diabetes | Disease
Journal Article
Hepatology, ISSN 0270-9139, 06/2013, Volume 57, Issue 6, p. 2525
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in adults and children. A number of genetic and environmental factors are...
Liver diseases | Hepatology | Insulin resistance | Liver cirrhosis
Liver diseases | Hepatology | Insulin resistance | Liver cirrhosis
Journal Article
Hepatology, ISSN 0270-9139, 06/2013, Volume 57, Issue 6, pp. 2525 - 2531
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in adults and children. A number of genetic and environmental factors are...
METABOLIC SYNDROME | OBESE ADOLESCENTS | HEALTHY-SUBJECTS | DENSITY-LIPOPROTEIN | VISCERAL ADIPOSITY | OVERWEIGHT/OBESE HUMANS | CORN SYRUP | GASTROENTEROLOGY & HEPATOLOGY | INSULIN SENSITIVITY | GLUCOSE-SWEETENED BEVERAGES | URIC-ACID | Animals | Fructose - adverse effects | Humans | Liver - metabolism | Dietary Carbohydrates - adverse effects | Lipogenesis | Fatty Liver - etiology
METABOLIC SYNDROME | OBESE ADOLESCENTS | HEALTHY-SUBJECTS | DENSITY-LIPOPROTEIN | VISCERAL ADIPOSITY | OVERWEIGHT/OBESE HUMANS | CORN SYRUP | GASTROENTEROLOGY & HEPATOLOGY | INSULIN SENSITIVITY | GLUCOSE-SWEETENED BEVERAGES | URIC-ACID | Animals | Fructose - adverse effects | Humans | Liver - metabolism | Dietary Carbohydrates - adverse effects | Lipogenesis | Fatty Liver - etiology
Journal Article
Hepatology, ISSN 0270-9139, 06/2012, Volume 55, Issue 6, pp. 2005 - 2023
ALL-CAUSE MORTALITY | LIFE-STYLE INTERVENTION | PLACEBO-CONTROLLED-TRIAL | CHRONIC HEPATITIS-C | MODERATE ALCOHOL-CONSUMPTION | POPULATION-BASED COHORT | RANDOMIZED CONTROLLED-TRIAL | VITAMIN-E SUPPLEMENTATION | GASTROENTEROLOGY & HEPATOLOGY | TYPE-2 DIABETES-MELLITUS | INSULIN-SENSITIZING AGENTS | Life Style | Thiazolidinediones - therapeutic use | Fatty Liver - diagnosis | Metformin - therapeutic use | Prevalence | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Risk Factors | Non-alcoholic Fatty Liver Disease | Vitamin E - therapeutic use | Fatty Liver - therapy | Fatty Liver - epidemiology
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9972, pp. 956 - 965
Summary Background The bile acid derivative 6-ethylchenodeoxycholic acid (obeticholic acid) is a potent activator of the farnesoid X nuclear receptor that...
Internal Medicine | FXR | MEDICINE, GENERAL & INTERNAL | NAFLD | THERAPY | GLUCOSE-METABOLISM | FATTY LIVER-DISEASE | INSULIN-RESISTANCE | RATS | NASH | BILE-ACIDS | AGONIST | Liver Cirrhosis - drug therapy | Liver - enzymology | Double-Blind Method | Administration, Oral | Cholesterol, HDL - metabolism | Receptors, Cytoplasmic and Nuclear - drug effects | Humans | Middle Aged | Male | Treatment Outcome | Chenodeoxycholic Acid - administration & dosage | Weight Loss - drug effects | Chenodeoxycholic Acid - analogs & derivatives | Non-alcoholic Fatty Liver Disease - drug therapy | Chenodeoxycholic Acid - adverse effects | Non-alcoholic Fatty Liver Disease - enzymology | Cholesterol, LDL - metabolism | Female | Clinical trials | Liver cirrhosis | Analysis | Deoxycholic acid | Liver diseases | Acids | Biopsy | Liver | Mortality | Ligands | Histology
Internal Medicine | FXR | MEDICINE, GENERAL & INTERNAL | NAFLD | THERAPY | GLUCOSE-METABOLISM | FATTY LIVER-DISEASE | INSULIN-RESISTANCE | RATS | NASH | BILE-ACIDS | AGONIST | Liver Cirrhosis - drug therapy | Liver - enzymology | Double-Blind Method | Administration, Oral | Cholesterol, HDL - metabolism | Receptors, Cytoplasmic and Nuclear - drug effects | Humans | Middle Aged | Male | Treatment Outcome | Chenodeoxycholic Acid - administration & dosage | Weight Loss - drug effects | Chenodeoxycholic Acid - analogs & derivatives | Non-alcoholic Fatty Liver Disease - drug therapy | Chenodeoxycholic Acid - adverse effects | Non-alcoholic Fatty Liver Disease - enzymology | Cholesterol, LDL - metabolism | Female | Clinical trials | Liver cirrhosis | Analysis | Deoxycholic acid | Liver diseases | Acids | Biopsy | Liver | Mortality | Ligands | Histology
Journal Article
JAMA, ISSN 0098-7484, 04/2011, Volume 305, Issue 16, pp. 1659 - 1668
CONTEXT Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in US children and adolescents and can present with advanced fibrosis...
MEDICINE, GENERAL & INTERNAL | STEATOHEPATITIS | THERAPY | HISTOPATHOLOGY | Hypoglycemic Agents - therapeutic use | Severity of Illness Index | Obesity | Metformin - therapeutic use | Double-Blind Method | Humans | Male | Treatment Outcome | Alanine Transaminase - blood | Fatty Liver - drug therapy | Antioxidants - therapeutic use | Adolescent | Fatty Liver - enzymology | Non-alcoholic Fatty Liver Disease | Vitamin E - therapeutic use | Female | Child | Clinical trials | Teenagers | Liver diseases | Vitamin E | Children & youth
MEDICINE, GENERAL & INTERNAL | STEATOHEPATITIS | THERAPY | HISTOPATHOLOGY | Hypoglycemic Agents - therapeutic use | Severity of Illness Index | Obesity | Metformin - therapeutic use | Double-Blind Method | Humans | Male | Treatment Outcome | Alanine Transaminase - blood | Fatty Liver - drug therapy | Antioxidants - therapeutic use | Adolescent | Fatty Liver - enzymology | Non-alcoholic Fatty Liver Disease | Vitamin E - therapeutic use | Female | Child | Clinical trials | Teenagers | Liver diseases | Vitamin E | Children & youth
Journal Article