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1. Full Text PAX8 expression in ovarian surface epithelial cells
by Adler, Emily, BS and Mhawech-Fauceglia, Paulette, MD and Gayther, Simon A., PhD and Lawrenson, Kate, PhD
Human pathology, ISSN 0046-8177, 2015, Volume 46, Issue 7, pp. 948 - 956
Pathology | Ovarian surface epithelium | CMYC | PAX8 | Fallopian tube epithelial cells | Inclusion cyst | High-grade serous ovarian carcinoma | Life Sciences & Biomedicine | Science & Technology | Neoplasms, Cystic, Mucinous, and Serous - metabolism | Paired Box Transcription Factors - genetics | Epithelial Cells - metabolism | Cadherins - metabolism | Humans | Ovarian Neoplasms - pathology | RNA, Messenger - metabolism | Neoplasms, Cystic, Mucinous, and Serous - genetics | Ovarian Neoplasms - genetics | Neoplasm Grading | Transfection | Cell Transformation, Neoplastic - genetics | Female | Ovarian Neoplasms - metabolism | Ovary - metabolism | Cell Line | Ovary - pathology | Neoplasms, Cystic, Mucinous, and Serous - pathology | Neoplasm Invasiveness | Calbindin 2 - metabolism | Epithelial Cells - pathology | Cell Transformation, Neoplastic - metabolism | Cell Transformation, Neoplastic - pathology | PAX8 Transcription Factor | Paired Box Transcription Factors - metabolism | Cell Movement | Immunohistochemistry | RNA | Cytochemistry | Analysis | Ovarian cancer | Flow cytometry | Immunoglobulins | Medical prognosis | Index Medicus | inclusion cyst | fallopian tube epithelial cells | ovarian surface epithelium | high-grade serous ovarian carcinoma
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2. Full Text A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro
by Myungjin Lee, Janet and Mhawech-Fauceglia, Paulette and Lee, Nathan and Cristina Parsanian, Lucineh and Gail Lin, Yvonne and Andrew Gayther, Simon and Lawrenson, Kate
Laboratory investigation, ISSN 0023-6837, 05/2013, Volume 93, Issue 5, pp. 528 - 542
microenvironment | chemoresistance | chemoresponse | epithelial ovarian cancer | three-dimensional modeling | cell adhesion | Pathology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Tumor Microenvironment | Cell Growth Processes - physiology | Drug Resistance, Neoplasm | Cell Culture Techniques - methods | Biomarkers, Tumor - metabolism | Cytoskeletal Proteins - metabolism | Female | Antineoplastic Agents - pharmacology | Ovarian Neoplasms - metabolism | Epithelial Cells - cytology | Spheroids, Cellular | Ovarian Neoplasms - drug therapy | Cell Culture Techniques - instrumentation | Cell Adhesion | Xenograft Model Antitumor Assays | Animals | Analysis of Variance | Histocytochemistry | Cell Line, Tumor | Mice | Index Medicus
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3. Full Text Genetics and Epigenetics of Infertility and Treatments on Outcomes
by Pisarska, Margareta D and Chan, Jessica L and Lawrenson, Kate and Gonzalez, Tania L and Wang, Erica T
The journal of clinical endocrinology and metabolism, ISSN 0021-972X, 06/2019, Volume 104, Issue 6, pp. 1871 - 1886
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Genomic Imprinting | United States - epidemiology | Endometriosis - diagnosis | Endometriosis - genetics | Prenatal Exposure Delayed Effects - epidemiology | Humans | Embryo Implantation - genetics | Prenatal Exposure Delayed Effects - prevention & control | Endometriosis - complications | Polycystic Ovary Syndrome - diagnosis | DNA Methylation | Polycystic Ovary Syndrome - complications | Infertility, Female - etiology | Observational Studies as Topic | Female | Child Health | Placentation - genetics | Child | Genome-Wide Association Study | Maternal Health | Infertility, Female - epidemiology | Treatment Outcome | Prenatal Exposure Delayed Effects - etiology | Reproductive Techniques, Assisted | Polycystic Ovary Syndrome - therapy | Randomized Controlled Trials as Topic | Pregnancy | Endometriosis - therapy | Polycystic Ovary Syndrome - genetics | Pregnancy Outcome | Infertility, Female - diagnosis | Infertility, Female - therapy | In vitro fertilization | Polycystic ovary syndrome | Phenotypes | Fertilization | Fetuses | Endometriosis | Implantation | Genomes | Reproduction | Infertility | Epigenetics | Reproductive technologies | Diagnosis | Index Medicus | Abridged Index Medicus
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4. Full Text A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets
by Jia, Dongyu and Liu, Zhenqiu and Deng, Nan and Tan, Tuan Zea and Huang, Ruby Yun-Ju and Taylor-Harding, Barbie and Cheon, Dong-Joo and Lawrenson, Kate and Wiedemeyer, Wolf R and Walts, Ann E and Karlan, Beth Y and Orsulic, Sandra
Cancer letters, ISSN 0304-3835, 2016, Volume 382, Issue 2, pp. 203 - 214
Hematology, Oncology and Palliative Medicine | Cancer-associated fibroblasts | Myofibroblasts | Tumor microenvironment | Pan-cancer | Therapeutic targets | Life Sciences & Biomedicine | Oncology | Science & Technology | Cancer-Associated Fibroblasts - metabolism | Coculture Techniques | Humans | Actins - metabolism | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Transcriptome | Databases, Genetic | Neoplasms, Glandular and Epithelial - metabolism | Tumor Microenvironment | Myofibroblasts - metabolism | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Collagen Type I - genetics | Neoplasm Grading | Time Factors | Biomarkers, Tumor - metabolism | Ovarian Neoplasms - metabolism | Myofibroblasts - pathology | Neoplasms, Glandular and Epithelial - pathology | Collagen Type I - metabolism | Kaplan-Meier Estimate | Neoplasms, Glandular and Epithelial - therapy | Gene Expression Profiling - methods | Disease-Free Survival | Cancer-Associated Fibroblasts - pathology | Carcinoma, Ovarian Epithelial | Cell Line, Tumor | Ovarian Neoplasms - therapy | Biomarkers, Tumor - genetics | Neoplasm Staging | Genetic aspects | Health aspects | Genes | Cancer | Index Medicus | cancer-associated fibroblasts | pan-cancer | therapeutic targets | tumor microenvironment | myofibroblasts
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5. Full Text Abstract 514: Lncrnauca1interacts directly with angiomotin to activate Hippo-YAP signaling in epithelial ovarian cancer
by Lin, Xianzhi and Spindler, Tassja J and Gayther, Simon A and Lawrenson, Kate
Cancer research (Chicago, Ill.), ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 514 - 514
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6. Full Text Down-regulation of ARID1A is sufficient to initiate neoplastic transformation along with epigenetic reprogramming in non-tumorigenic endometriotic cells
by Lakshminarasimhan, Ranjani and Andreu-Vieyra, Claudia and Lawrenson, Kate and Duymich, Christopher E and Gayther, Simon A and Liang, Gangning and Jones, Peter A
Cancer letters, ISSN 0304-3835, 2017, Volume 401, pp. 11 - 19
Hematology, Oncology and Palliative Medicine | Ovarian clear cell carcinoma | Epigenetics | Endometriosis | Phenotypic transformation | ARID1A | Life Sciences & Biomedicine | Oncology | Science & Technology | Cell Proliferation | Endometriosis - genetics | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Male | Cellular Reprogramming | Ovarian Neoplasms - genetics | DNA Methylation | Transfection | RNA Interference | Cell Transformation, Neoplastic - genetics | Female | Ovarian Neoplasms - metabolism | Nuclear Proteins - genetics | Endometrium - metabolism | Cell Line | Promoter Regions, Genetic | Signal Transduction | Down-Regulation | Chromatin Assembly and Disassembly | Nuclear Proteins - metabolism | Endometriosis - pathology | Transcription Factors - genetics | Cell Adhesion | Cell Transformation, Neoplastic - metabolism | Transcription Factors - metabolism | Phenotype | Endometriosis - metabolism | Histones - metabolism | Cell Transformation, Neoplastic - pathology | Endometrium - pathology | Cell Movement | Antimitotic agents | Epigenetic inheritance | Medical colleges | Chromatin | Collagen | Analysis | Molecular biology | Antineoplastic agents | Methylation | Integrins | Index Medicus | endometriosis | ovarian clear cell carcinoma | epigenetics | phenotypic transformation
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7. Full Text CAUSEL: An epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants
by Spisák, Sándor and Lawrenson, Kate and Fu, Yanfang and Csabai, István and Cottman, Rebecca T and Seo, Ji-Heui and Haiman, Christopher and Han, Ying and Lenci, Romina and Li, Qiyuan and Tisza, Viktória and Szállási, Zoltán and Herbert, Zachery T and Chabot, Matthew and Pomerantz, Mark and Solymosi, Norbert and Gayther, Simon A and Joung, J Keith and Freedman, Matthew L and GAME-ON ELLIPSE Consortium and GAME-ON/ELLIPSE Consortium and The GAME-ON/ELLIPSE Consortium
Nature medicine, ISSN 1078-8956, 11/2015, Volume 21, Issue 11, pp. 1357 - 1363
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Genetic Predisposition to Disease | Genome-Wide Association Study | Epigenomics | Humans | Male | Chromosome Mapping | Transcription Factors - genetics | DNA-Binding Proteins - genetics | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Regulatory Factor X Transcription Factors | Chromosomes, Human, Pair 6 - genetics | Homeodomain Proteins - genetics | Prostatic Neoplasms - genetics | Alleles | Cell Line, Tumor | Histone Code | Polymorphism, Single Nucleotide | Histones - metabolism | Gene Expression Regulation, Neoplastic - genetics | Genome-wide association studies | Usage | Genetic aspects | Single nucleotide polymorphisms | Research | Prostate cancer | Genetic screening | Epigenetics | Genotype & phenotype | Genomics | Polymorphism | Index Medicus
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8. Full Text Transcription factors in epithelial ovarian cancer: histotype-specific drivers and novel therapeutic targets
by Nameki, Robbin and Chang, Heidi and Reddy, Jessica and Corona, Rosario I and Lawrenson, Kate
Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 2020, pp. 107722 - 107722
PAX8 | FOXM1 | Transcription factor | Epithelial ovarian cancer | Gene regulation | MYC | Index Medicus
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9. Full Text Senescent Fibroblasts Promote Neoplastic Transformation of Partially Transformed Ovarian Epithelial Cells in a Three-dimensional Model of Early Stage Ovarian Cancer
by Lawrenson, Kate and Grun, Barbara and Benjamin, Elizabeth and Jacobs, Ian J and Dafou, Dimitra and Gayther, Simon A
Neoplasia (New York, N.Y.), ISSN 1476-5586, 04/2010, Volume 12, Issue 4, pp. 317,IN3 - 325,IN3
Life Sciences & Biomedicine | Oncology | Science & Technology | Cell Proliferation | Epithelial Cells - metabolism | Fibroblasts - physiology | Humans | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Neoplasms, Glandular and Epithelial - metabolism | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Telomerase - genetics | Cell Transformation, Neoplastic - genetics | Female | Telomerase - metabolism | Ovarian Neoplasms - metabolism | Cell Culture Techniques | Fibroblasts - metabolism | Ovary - metabolism | Cellular Senescence - genetics | Neoplasms, Glandular and Epithelial - pathology | Ovary - pathology | Cells, Cultured | Cellular Senescence - physiology | Epithelial Cells - pathology | Fibroblasts - pathology | Cell Transformation, Neoplastic - metabolism | Cell Line, Transformed - pathology | Genes, myc - genetics | Cell Transformation, Neoplastic - pathology | Neoplasm Staging | Index Medicus
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