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Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2017, Volume 60, Issue 15, pp. 6649 - 6663
Recent data demonstrated that activation of the muscarinic M1 receptor by a subtype-selective positive allosteric modulator (PAM) contributes to the... 
Index Medicus
Journal Article
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ISSN 0960-894X, 01/2016, Volume 26, Issue 2, pp. 650 - 655
Selective activation of the M-1 receptor via a positive allosteric modulator (PAM) is a new approach for the treatment of the cognitive impairments associated... 
ACTIVATION | CHEMISTRY, MEDICINAL | SERIES | ALZHEIMERS-DISEASE | CHEMISTRY, ORGANIC | SCHIZOPHRENIA | XANOMELINE | Azaindole amide | AGONISTS | DISCOVERY | M-1 selective activator | MUSCARINIC ACETYLCHOLINE-RECEPTOR | M-1 positive allosteric modulator (PAM) | Intra-molecular hydrogen bond (IMHB) | IN-VIVO | CENTRAL-NERVOUS-SYSTEM
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 06/2019, Volume 10, Issue 6, pp. 941 - 948
It has been hypothesized that selective muscarinic acetylcholine receptor (mAChR) M4 subtype activation could provide therapeutic benefits to a number of... 
carbamate isosteres | M4 mAChR | selective mAChR agonist | ensemble docking | electrostatic potential isosurface | Muscarinic acetylcholine receptor | CHEMISTRY, MEDICINAL | XANOMELINE | ALLOSTERIC MODULATION | MODEL | M-1 | POTENT | DERIVATIVES
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2014, Volume 57, Issue 3, pp. 861 - 877
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2017, Volume 60, Issue 18, pp. 7764 - 7780
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2015, Volume 58, Issue 10, pp. 4291 - 4308
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2011, Volume 54, Issue 6, pp. 1724 - 1739
Journal Article
Journal of medicinal chemistry, 08/2017, Volume 60, Issue 15, p. 6649
Journal Article
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