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by Gieger, Christian and Radhakrishnan, Aparna and Cvejic, Ana and Tang, Weihong and Porcu, Eleonora and Pistis, Giorgio and Serbanovic-Canic, Jovana and Elling, Ulrich and Goodall, Alison H and Labrune, Yann and Lopez, Lorna M and Mägi, Reedik and Meacham, Stuart and Okada, Yukinori and Pirastu, Nicola and Sorice, Rossella and Teumer, Alexander and Voss, Katrin and Zhang, Weihua and Ramirez-Solis, Ramiro and Bis, Joshua C and Ellinghaus, David and Gögele, Martin and Hottenga, Jouke-Jan and Langenberg, Claudia and Kovacs, Peter and O’Reilly, Paul F and Shin, So-Youn and Esko, Tõnu and Hartiala, Jaana and Kanoni, Stavroula and Murgia, Federico and Parsa, Afshin and Stephens, Jonathan and van der Harst, Pim and Ellen van der Schoot, C and Allayee, Hooman and Attwood, Antony and Balkau, Beverley and Bastardot, François and Basu, Saonli and Baumeister, Sebastian E and Biino, Ginevra and Bomba, Lorenzo and Bonnefond, Amélie and Cambien, François and Chambers, John C and Cucca, Francesco and D’Adamo, Pio and Davies, Gail and de Boer, Rudolf A and de Geus, Eco J. C and Döring, Angela and Elliott, Paul and Erdmann, Jeanette and Evans, David M and Falchi, Mario and Feng, Wei and Folsom, Aaron R and Frazer, Ian H and Gibson, Quince D and Glazer, Nicole L and Hammond, Chris and Hartikainen, Anna-Liisa and Heckbert, Susan R and Hengstenberg, Christian and Hersch, Micha and Illig, Thomas and Loos, Ruth J. F and Jolley, Jennifer and Khaw, Kay-Tee and Kühnel, Brigitte and Kyrtsonis, Marie-Christine and Lagou, Vasiliki and Lloyd-Jones, Heather and Lumley, Thomas and Mangino, Massimo and Maschio, Andrea and Mateo Leach, Irene and McKnight, Barbara and Memari, Yasin and Mitchell, Braxton D and Montgomery, Grant W and Nakamura, Yusuke and Nauck, Matthias and Navis, Gerjan and Nöthlings, Ute and Nolte, Ilja M and Porteous, David J and Pouta, Anneli and Pramstaller, Peter P and Pullat, Janne and Ring, Susan M and Rotter, Jerome I and Ruggiero, Daniela and Ruokonen, Aimo and Sala, Cinzia and Samani, Nilesh J and Sambrook, Jennifer and Schlessinger, David and ...
Nature (London), ISSN 1476-4687, 11/2011, Volume 480, Issue 7376, pp. 201 - 208
Journal Article
PloS one, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0167195 - e0167195
...Author(s): Minke H. T. Hartman 1, Inge Vreeswijk-Baudoin 1, Hilde E. Groot 1, Kees W. A. van de Kolk 2, Rudolf A. de Boer 1, Irene Mateo Leach 1,*, Rozemarijn... 
RHEUMATOID-ARTHRITIS | HEART | INFARCTION | DISEASE | ANTIBODY | MICE | MECHANISMS | CARDIOMYOCYTES | IL-6 RECEPTOR | TOCILIZUMAB | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Heart - physiopathology | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Male | Myocardium - pathology | Receptors, Interleukin-6 - antagonists & inhibitors | Myocardial Infarction - metabolism | Fibrosis - metabolism | Hypertrophy - metabolism | Myocardial Reperfusion Injury - physiopathology | Myocardial Reperfusion Injury - metabolism | Animals | Time Factors | Interleukin-6 - blood | Myocardial Infarction - pathology | Myocardium - metabolism | Heart - drug effects | Hemodynamics - drug effects | Myocardial Infarction - prevention & control | Interleukin-6 - metabolism | Ventricular Remodeling - drug effects | Microscopy, Fluorescence | Disease Models, Animal | Receptors, Interleukin-6 - metabolism | Prevention | Physiological aspects | Myocardial ischemia | Genetic aspects | Research | Drug therapy | Reperfusion injury | Interleukin-6 | Myocardial infarction | Heart | Animal models | Nuclear magnetic resonance--NMR | Heart attacks | Immunoglobulin G | Interleukin | Cardiovascular disease | Interleukin 6 | Signal transduction | Reperfusion | Ischemia | Rodents | Surgery | Interleukin 6 receptors | Cardiology | Heart diseases | Stretching | Heart failure | Cytokines | Magnetic resonance | Coronary artery | Glycoproteins | Inflammation | Coronary artery disease | Ostomy | Injury prevention | Magnetic resonance imaging | Rheumatoid arthritis | Coronary vessels | Fibrosis | Monoclonal antibodies | Infarction | Mice | Ventricle | Hemodynamics | Cardiovascular diseases | Respiration | Hypertrophy | Apoptosis | Index Medicus | Remodeling | Nuclear magnetic resonance | NMR
Journal Article
Trends in cardiovascular medicine, ISSN 1050-1738, 08/2018, Volume 28, Issue 6, pp. 369 - 379
Many cytokines are currently under investigation as potential target to improve cardiac function and outcome in the setting of acute myocardial infarction (MI)... 
Myocardial infarction | Heart failure | Immune modulation/therapy | Inflammation | Cytokines | C-REACTIVE PROTEIN | RHEUMATOID-ARTHRITIS | INTERLEUKIN-1 RECEPTOR ANTAGONIST | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | PRESERVED EJECTION FRACTION | FACTOR-ALPHA | TUMOR-NECROSIS-FACTOR | PERCUTANEOUS CORONARY INTERVENTION | TNF-ALPHA | ST-SEGMENT ELEVATION | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Inflammation Mediators - immunology | Humans | Translational Medical Research | Heart Failure - physiopathology | Myocardial Infarction - immunology | Heart Failure - drug therapy | Cardiovascular Agents - therapeutic use | Animals | Anti-Inflammatory Agents - adverse effects | Myocardial Infarction - drug therapy | Signal Transduction - drug effects | Heart Failure - immunology | Anti-Inflammatory Agents - therapeutic use | Myocardial Infarction - physiopathology | Inflammation Mediators - antagonists & inhibitors | Cytokines - antagonists & inhibitors | Cardiovascular Agents - adverse effects | Cytokines - immunology | Heart | Rheumatoid factor | Medical research | Interleukins | Analysis | Medicine, Experimental | Arthritis | Heart attack | Animal models | Heart attacks | Clinical trials | Cardiovascular disease | Interleukin 6 | Ischemia | CXC chemokines | Interleukin 6 receptors | Rodents | Interleukin 1 | Tumor necrosis factor-TNF | Experimental research | Heart diseases | Interleukin 8 | Age | Immune system | Antigens | Translation | Interleukin 1 receptor antagonist | Mortality | Cardiomyocytes | Tumor necrosis factor-α | Gene expression | Studies | Monocytes | Monocyte chemoattractant protein | Rheumatoid arthritis | Coronary vessels | Cardiac function | TNF inhibitors | Monocyte chemoattractant protein 1 | Chemokines | Apoptosis | Veins & arteries | Index Medicus
Journal Article
by Lu, Yingchang and Day, Felix R and Gustafsson, Stefan and Buchkovich, Martin L and Na, Jianbo and Bataille, Veronique and Cousminer, Diana L and Dastani, Zari and Drong, Alexander W and Esko, Tõnu and Evans, David M and Falchi, Mario and Feitosa, Mary F and Ferreira, Teresa and Hedman, Åsa K and Haring, Robin and Hysi, Pirro G and Iles, Mark M and Justice, Anne E and Kanoni, Stavroula and Lagou, Vasiliki and Li, Rui and Li, Xin and Locke, Adam and Lu, Chen and Mägi, Reedik and Perry, John R. B and Pers, Tune H and Qi, Qibin and Sanna, Marianna and Schmidt, Ellen M and Scott, William R and Shungin, Dmitry and Teumer, Alexander and Vinkhuyzen, Anna A. E and Walker, Ryan W and Westra, Harm-Jan and Zhang, Mingfeng and Zhang, Weihua and Zhao, Jing Hua and Zhu, Zhihong and Afzal, Uzma and Ahluwalia, Tarunveer Singh and Bakker, Stephan J. L and Bellis, Claire and Bonnefond, Amélie and Borodulin, Katja and Buchman, Aron S and Cederholm, Tommy and Choh, Audrey C and Choi, Hyung Jin and Curran, Joanne E and de Groot, Lisette C. P. G. M and De Jager, Philip L and Dhonukshe-Rutten, Rosalie A. M and Enneman, Anke W and Eury, Elodie and Evans, Daniel S and Forsen, Tom and Friedrich, Nele and Fumeron, Frédéric and Garcia, Melissa E and Gärtner, Simone and Han, Bok-Ghee and Havulinna, Aki S and Hayward, Caroline and Hernandez, Dena and Hillege, Hans and Ittermann, Till and Kent, Jack W and Kolcic, Ivana and Laatikainen, Tiina and Lahti, Jari and Leach, Irene Mateo and Lee, Christine G and Lee, Jong-Young and Liu, Tian and Liu, Youfang and Lobbens, Stéphane and Loh, Marie and Lyytikäinen, Leo-Pekka and Medina-Gomez, Carolina and Michaëlsson, Karl and Nalls, Mike A and Nielson, Carrie M and Oozageer, Laticia and Pascoe, Laura and Paternoster, Lavinia and Polašek, Ozren and Ripatti, Samuli and Sarzynski, Mark A and Shin, Chan Soo and Narančić, Nina Smolej and Spira, Dominik and Srikanth, Priya and Steinhagen-Thiessen, Elisabeth and Sung, Yun Ju and Swart, Karin M. A and Taittonen, Leena and Tanaka, Toshiko and ... and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Nature communications, ISSN 2041-1723, 02/2016, Volume 7, Issue 1, pp. 10495 - 10495
Journal Article
by Codd, Veryan and Nelson, Christopher P and Albrecht, Eva and Mangino, Massimo and Deelen, Joris and Buxton, Jessica L and Hottenga, Jouke Jan and Fischer, Krista and Esko, Tõnu and Surakka, Ida and Broer, Linda and Nyholt, Dale R and Leach, Irene Mateo and Salo, Perttu and Hägg, Sara and Matthews, Mary K and Palmen, Jutta and Norata, Giuseppe D and O'Reilly, Paul F and Saleheen, Danish and Amin, Najaf and Balmforth, Anthony J and Beekman, Marian and de Boer, Rudolf A and Böhringer, Stefan and Braund, Peter S and Burton, Paul R and Craen, Anton J Mde and Denniff, Matthew and Dong, Yanbin and Douroudis, Konstantinos and Dubinina, Elena and Eriksson, Johan G and Garlaschelli, Katia and Guo, Dehuang and Hartikainen, Anna-Liisa and Henders, Anjali K and Houwing-Duistermaat, Jeanine J and Kananen, Laura and Karssen, Lennart C and Kettunen, Johannes and Klopp, Norman and Lagou, Vasiliki and van Leeuwen, Elisabeth M and Madden, Pamela A and Mägi, Reedik and Magnusson, Patrik K E and Männistö, Satu and McCarthy, Mark I and Medland, Sarah E and Mihailov, Evelin and Montgomery, Grant W and Oostra, Ben A and Palotie, Aarno and Peters, Annette and Pollard, Helen and Pouta, Anneli and Prokopenko, Inga and Ripatti, Samuli and Salomaa, Veikko and Suchiman, H Eka D and Valdes, Ana M and Verweij, Niek and Viñuela, Ana and Wang, Xiaoling and Wichmann, H-Erich and Widen, Elisabeth and Willemsen, Gonneke and Wright, Margaret J and Xia, Kai and Xiao, Xiangjun and van Veldhuisen, Dirk J and Catapano, Alberico L and Tobin, Martin D and Hall, Alistair S and Blakemore, Alexandra I F and van Gilst, Wiek H and Zhu, Haidong and Erdmann, Jeanette and Reilly, Muredach P and Kathiresan, Sekar and Schunkert, Heribert and Talmud, Philippa J and Pedersen, Nancy L and Perola, Markus and Ouwehand, Willem and Kaprio, Jaakko and Martin, Nicholas G and van Duijn, Cornelia M and Hovatta, Iiris and Gieger, Christian and Metspalu, Andres and Boomsma, Dorret I and Jarvelin, Marjo-Riitta and Slagboom, P Eline and Thompson, John R and Spector, Tim D and van der Harst, Pim and Samani, Nilesh J and CARDIoGRAM consortium and CARDIoGRAM Consortium
Nature genetics, ISSN 1546-1718, 03/2013, Volume 45, Issue 4, pp. 422 - 427
Journal Article
by van der Harst, Pim and Zhang, Weihua and Mateo Leach, Irene and Rendon, Augusto and Verweij, Niek and Sehmi, Joban and Paul, Dirk S and Elling, Ulrich and Allayee, Hooman and Li, Xinzhong and Radhakrishnan, Aparna and Tan, Sian-Tsung and Voss, Katrin and Weichenberger, Christian X and Albers, Cornelis A and Al-Hussani, Abtehale and Asselbergs, Folkert W and Ciullo, Marina and Danjou, Fabrice and Dina, Christian and Esko, Tõnu and Evans, David M and Franke, Lude and Gögele, Martin and Hartiala, Jaana and Hersch, Micha and Holm, Hilma and Hottenga, Jouke-Jan and Kanoni, Stavroula and Kleber, Marcus E and Lagou, Vasiliki and Langenberg, Claudia and Lopez, Lorna M and Lyytikäinen, Leo-Pekka and Melander, Olle and Murgia, Federico and Nolte, Ilja M and O’Reilly, Paul F and Padmanabhan, Sandosh and Parsa, Afshin and Pirastu, Nicola and Porcu, Eleonora and Portas, Laura and Prokopenko, Inga and Ried, Janina S and Shin, So-Youn and Tang, Clara S and Teumer, Alexander and Traglia, Michela and Ulivi, Sheila and Westra, Harm-Jan and Yang, Jian and Hua Zhao, Jing and Anni, Franco and Abdellaoui, Abdel and Attwood, Antony and Balkau, Beverley and Bandinelli, Stefania and Bastardot, François and Benyamin, Beben and Boehm, Bernhard O and Cookson, William O and Das, Debashish and de Bakker, Paul I. W and de Boer, Rudolf A and de Geus, Eco J. C and de Moor, Marleen H and Dimitriou, Maria and Domingues, Francisco S and Döring, Angela and Engström, Gunnar and Ingi Eyjolfsson, Gudmundur and Ferrucci, Luigi and Fischer, Krista and Galanello, Renzo and Garner, Stephen F and Genser, Bernd and Gibson, Quince D and Girotto, Giorgia and Fannar Gudbjartsson, Daniel and Harris, Sarah E and Hartikainen, Anna-Liisa and Hastie, Claire E and Hedblad, Bo and Illig, Thomas and Jolley, Jennifer and Kähönen, Mika and Kema, Ido P and Kemp, John P and Liang, Liming and Lloyd-Jones, Heather and Loos, Ruth J. F and Meacham, Stuart and Medland, Sarah E and Meisinger, Christa and Memari, Yasin and Mihailov, Evelin and Miller, Kathy and Moffatt, Miriam F and Nauck, Matthias and ...
Nature (London), ISSN 1476-4687, 12/2012, Volume 492, Issue 7429, pp. 369 - 375
Journal Article