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1. Full Text Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
by Astrup, A and Carraro, R and Finer, N and Harper, A and Kunesova, M and Lean, M.E.J and Niskanen, L and Rasmussen, M.F and Rissanen, A and Rössner, S and Savolainen, M.J and Van Gaal, L and NN8022-1807 Investigators and on behalf of the NN8022-1807 Investigators
International Journal of Obesity, ISSN 0307-0565, 06/2012, Volume 36, Issue 6, pp. 843 - 854
Objective: Having demonstrated short-term weight loss with liraglutide in this group of obese adults, we now evaluate safety/tolerability (primary outcome) and... 
liraglutide | weight loss | GLP-1 analog | OBESITY | NUTRITION & DIETETICS | REDUCTION | DIET | OVERWEIGHT | ENDOCRINOLOGY & METABOLISM | SIBUTRAMINE | LIFE | Obesity - diet therapy | Prediabetic State - diet therapy | Obesity - drug therapy | Humans | Middle Aged | Male | Weight Loss - drug effects | Prediabetic State - drug therapy | Anti-Obesity Agents - therapeutic use | Young Adult | Adult | Female | Prediabetic State - epidemiology | Exercise Therapy - methods | Double-Blind Method | Drug Administration Schedule | Risk Reduction Behavior | Glucagon-Like Peptide 1 - analogs & derivatives | Prediabetic State - prevention & control | Europe - epidemiology | Treatment Outcome | Analysis of Variance | Obesity - epidemiology | Obesity - prevention & control | Adolescent | Aged | Liraglutide | Glucagon-Like Peptide 1 - therapeutic use | Prevention | Body mass index | Weight loss | Physiological aspects | Research | Cardiovascular diseases | Risk factors | Obesity | Sponsorship | Weight control | Cardiorespiratory | Lipids | Adults | Safety | Diet (weight control) | Original
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2. Clinical handbook of weight management
by Lean, Michael E. J
1998, ISBN 9781853175428, vi, 113
Prevention | Obesity | prevention & control | Management | therapy | Weight loss
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3. Full Text Type 2 diabetes remission: economic evaluation of the DiRECT/Counterweight‐Plus weight management programme within a primary care randomized controlled trial
by Xin, Y and Davies, A and McCombie, L and Briggs, A and Messow, C.‐M and Grieve, E and Leslie, W. S and Taylor, R and Lean, M. E. J
Diabetic Medicine, ISSN 0742-3071, 08/2019, Volume 36, Issue 8, pp. 1003 - 1012
Aim The Counterweight‐Plus weight management programme achieved 46% remission of Type 2 diabetes at 1 year in the DiRECT trial. We estimated the implementation... 
SURGERY | INDIVIDUALS | COST-EFFECTIVENESS | OBESITY | LIFE-STYLE | GLUCOSE | ENDOCRINOLOGY & METABOLISM | MELLITUS | ASSOCIATION | CARDIOVASCULAR RISK-FACTORS | Type 2 diabetes | Hypertension | Analysis | Clinical trials | Hypoglycemic agents | Diabetes therapy | Medical care, Cost of | Nutrient deficiency | Diabetes mellitus | Remission | Diabetes | Diabetes mellitus (non-insulin dependent) | Cost control
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4. Full Text Fludrocortisone therapy for persistent hyperkalaemia
by Dobbin, S. J. H and Petrie, J. R and Lean, M. E. J and McKay, G. A
Diabetic Medicine, ISSN 0742-3071, 07/2017, Volume 34, Issue 7, pp. 1005 - 1008
Background Type 4 renal tubular acidosis causes hyperkalaemia, for which diabetes and medications commonly used in this patient group are aetiological factors.... 
DIABETES-MELLITUS | ACIDOSIS | HYPORENINEMIC HYPOALDOSTERONISM | IRBESARTAN | NEPHROPATHY | ENDOCRINOLOGY & METABOLISM | Kidney Failure, Chronic - physiopathology | Kidney Failure, Chronic - immunology | Kidney - drug effects | Comorbidity | Humans | Middle Aged | Kidney - immunology | Treatment Outcome | Acidosis, Renal Tubular - epidemiology | Secondary Prevention | Diabetes Mellitus, Type 2 - epidemiology | Fludrocortisone - therapeutic use | Acidosis, Renal Tubular - drug therapy | Kidney Failure, Chronic - epidemiology | Hyperkalemia - epidemiology | Anti-Inflammatory Agents - therapeutic use | Female | Hyperkalemia - prevention & control | Acidosis, Renal Tubular - etiology | Acidosis, Renal Tubular - physiopathology | Kidney - physiopathology | Hyperkalemia - etiology | Type 2 diabetes | Care and treatment | Kidney diseases | Carbonates | Creatinine | Renal function | Epidermal growth factor receptors | Diabetes mellitus | Albumin | Urinary tract | Renal tubular acidosis | Leg | Urea | Bicarbonate | Renal insufficiency | Sodium | Ulcers | Renal failure | Leg ulcers | Respiratory tract diseases | Sepsis | Diabetes | Acidosis | Potassium | Kidney transplantation
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5. Full Text The DiRECT principles: giving Type 2 diabetes remission programmes the best chance of success
by Hopkins, M. D and Taylor, R and Lean, M. E. J
Diabetic Medicine, ISSN 0742-3071, 12/2019, Volume 36, Issue 12, pp. 1703 - 1704
In 2017, the 12-month primary outcome results of the Diabetes UK-funded Diabetes Remission Clinical Trial (DiRECT) were published, providing randomized... 
Remission | Diabetes mellitus (non-insulin dependent)
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6. Full Text Weight losses with low-energy formula diets in obese patients with and without type 2 diabetes: systematic review and meta-analysis (vol 41, pg 96, 2017)
by Leslie, WS and Taylor, R and Harris, L and Lean, MEJ
INTERNATIONAL JOURNAL OF OBESITY, ISSN 0307-0565, 06/2017, Volume 41, Issue 6, pp. 997 - 997
  This corrects the article DOI: 10.1038/ijo.2016.175 
NUTRITION & DIETETICS | ENDOCRINOLOGY & METABOLISM
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7. Full Text Skeletal muscle mass estimation in Saudi adults – relationship with obesity and hypertension
by Alkhalaf, M. M and Edwards, C. A and Lean, M. E. J and Combet, E
Proceedings of the Nutrition Society, ISSN 0029-6651, 2015, Volume 74, Issue OCE2
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8. Full Text Weight losses with low-energy formula diets in obese patients with and without type 2 diabetes: systematic review and meta-analysis
by Leslie, W S and Taylor, R and Harris, L and Lean, M E J
International journal of obesity (2005), ISSN 0307-0565, 06/2017, Volume 41, Issue 6, pp. 997 - 997
This corrects the article DOI: 10.1038/ijo.2016.175. 
Corrigendum
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9. Full Text Erratum: Weight losses with low-energy formula diets in obese patients with and without type 2 diabetes: systematic review and meta-analysis
by Leslie, W S and Taylor, R and Harris, L and Lean, M E J
International Journal of Obesity, ISSN 0307-0565, 06/2017, Volume 41, Issue 6, pp. 997 - 997
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10. Full Text Erratum: Weight losses with low-energy formula diets in obese patients with and without type 2 diabetes: Systematic review and meta-analysis (International Journal of Obesity (2017) 41 (96-101) DOI: 10.1038/ijo.2016.175)
International Journal of Obesity, ISSN 0307-0565, 06/2017, Volume 41, Issue 6, p. 997
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11. Full Text The stigmata of obesity: thoughts and attitudes of adolescent school children
by Hutch, A and He, M and Costello, C and Reilly, A. M and Lean, M. E. J and Leslie, W. S and Hankey, C. R
Proceedings of the Nutrition Society, ISSN 0029-6651, 2015, Volume 74, Issue OCE1
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12. Full Text Risk classification paradox of anthropometric measurements in Saudi Arabia: need for further consideration
by Alkhalaf, M.M and Edwards, C.A and Lean, M.E.J and Combet, E
Proceedings of the Nutrition Society, ISSN 0029-6651, 2016, Volume 75, Issue OCE3
  Linear regression analysis showed significant increase in body weight, waist circumference and BMI for every 5 years increase in age (p < 0·001):... 
Obesity | Body mass index | Mens health | Womens health | Older people | Age
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13. Full Text Nutritional intervention and impact of polyphenol on glycohaemoglobin in type 2 diabetic subjects: systematic review and meta-analysis
by Palma-Duran, S. A and Vlassopoulos, A and Govan, L and Lean, M. E. J and Combet, E
Proceedings of the Nutrition Society, ISSN 0029-6651, 2015, Volume 74, Issue OCE2
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14. Full Text Roasted instant coffees: analysis of (poly)phenols and melanoidins antioxidant capacity, potassium and sodium contents
by Palma-Duran, S.A and Lean, M.E.J and Combet, E
Proceedings of the Nutrition Society, ISSN 0029-6651, 2016, Volume 75, Issue OCE2
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15. Full Text Protein-phenolic interactions and inhibition of glycation - combining a systematic review and experimental models for enhanced physiological relevance
by Vlassopoulos, A and Lean, M. E. J and Combet, E
Food & Function, ISSN 2042-6496, 9/2014, Volume 5, Issue 1, pp. 2646 - 2655
Background : while antiglycative capacity has been attributed to (poly)phenols, the exact mechanism of action remains unclear. Studies so far are often relying... 
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16. Full Text Altered gut and adipose tissue hormones in overweight and obese individuals: Cause or consequence
by Lean, M.E.J and Malkova, D
International Journal of Obesity, ISSN 0307-0565, 04/2016, Volume 40, Issue 4, pp. 622 - 632
The aim of this article is to review the research into the main peripheral appetite signals altered in human obesity, together with their modifications after... 
NUTRITION & DIETETICS | GASTROINTESTINAL SATIETY SIGNALS | PEPTIDE-YY LEVELS | PLASMA GHRELIN LEVELS | FOOD-INTAKE | DEPENDENT DIABETIC-PATIENTS | ENDOCRINOLOGY & METABOLISM | APPETITE CONTROL | INDUCED WEIGHT-LOSS | NORMAL DIETARY CONSUMPTION | PITUITARY-ADRENAL AXIS | LIBITUM ENERGY-INTAKE | Appetite | Humans | Obesity - physiopathology | Reference Values | Energy Intake | Gastrointestinal Tract - metabolism | Obesity - metabolism | Overweight - therapy | Adipose Tissue - metabolism | Overweight - metabolism | Energy Metabolism | Weight Loss | Gastrointestinal Hormones - metabolism | Obesity - therapy | Postprandial Period | Appetite Regulation - physiology | Satiation | Gastrointestinal Hormones - physiology | Obesity | Overweight persons | Usage | Analysis | Surgery | Weight loss | Health aspects | Risk factors | Review
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17. Full Text Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide (vol 36, pg 843, 2012)
by Astrup, A and Carraro, R and Finer, N and Harper, A and Kunesova, M and Lean, MEJ and Niskanen, L and Rasmussen, MF and Rissanen, A and Rossner, S and Savolainen, MJ and Van Gaal, L and NN8022-1807 Investigators
INTERNATIONAL JOURNAL OF OBESITY, ISSN 0307-0565, 02/2013, Volume 37, Issue 2, pp. 322 - 322
NUTRITION & DIETETICS | ENDOCRINOLOGY & METABOLISM
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18. Full Text Role of oxidative stress in physiological albumin glycation: A neglected interaction
by Vlassopoulos, A and Lean, M.E.J and Combet, E
Free Radical Biology and Medicine, ISSN 0891-5849, 07/2013, Volume 60, pp. 318 - 324
Protein glycation is a key mechanism involved in chronic disease development in both diabetic and nondiabetic individuals. About 12–18% of circulating proteins... 
Oxidative stress | Plasma | Hydrogen peroxide | Free radicals | Albumin | Glucose | Mercaptalbumin | Glycation | VITAMIN-E | METABOLITES | SERUM-ALBUMIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOSYLATED HEMOGLOBIN | SUPPLEMENTATION | INHIBITION | HUMAN-BLOOD | ANTIOXIDANT | ENDOCRINOLOGY & METABOLISM | HYDROGEN-PEROXIDE | PEOPLE | Oxidation-Reduction | Oxidative Stress | Glycated Hemoglobin A - metabolism | Humans | Glycosylation | Serum Albumin, Bovine - metabolism | Glycated Hemoglobin A - chemistry | Hydrogen Peroxide - chemistry | Animals | Cattle | Glucose - chemistry | Glucose - metabolism | Serum Albumin, Bovine - chemistry | Serum Albumin - chemistry | Serum Albumin - metabolism | Glucose metabolism | Analysis | Physiological aspects | Dextrose
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19. Full Text Lower bone turnover and relative bone deficits in men with metabolic syndrome: a matter of insulin sensitivity? The European Male Ageing Study
by Laurent, M R and Cook, M J and Gielen, E and Ward, K A and Antonio, L and Adams, J E and Decallonne, B and Bartfai, G and Casanueva, F F and Forti, G and Giwercman, A and Huhtaniemi, I T and Kula, K and Lean, M E. J and Lee, D M and Pendleton, N and Punab, M and Claessens, F and Wu, F C. W and Vanderschueren, D and Pye, S R and O’Neill, T W and EMAS Grp and EMAS Group and Reproduktionsmedicin, Malmö and Lund University and Reproductive medicine, Malmö and Lunds universitet
Osteoporosis International, ISSN 0937-941X, 11/2016, Volume 27, Issue 11, pp. 3227 - 3237
We examined cross-sectional associations of metabolic syndrome and its components with male bone turnover, density and structure. Greater bone mass in men with... 
Obesity | Medicine & Public Health | Peripheral quantitative computed tomography | Orthopedics | Rheumatology | Male | Bone mineral density | Bone turnover | Metabolic syndrome | Endocrinology | SEX STEROIDS | FRACTURE RISK | WOMEN | MINERAL DENSITY | ENDOCRINOLOGY & METABOLISM | BODY-MASS INDEX | OLDER MEN | COHORT | ELDERLY-MEN | HEALTH | ASSOCIATION | Bone and Bones - pathology | Bone Density | Cross-Sectional Studies | Humans | Middle Aged | Insulin Resistance | Hyperglycemia - complications | Metabolic Syndrome - complications | Aging | Adult | Aged | Bone Remodeling | Complications and side effects | Prognosis | Physiological aspects | Bones | Genetic aspects | Metabolic syndrome X | Research | Density | Radius | Femur | Osteocalcin | Procollagen | Spine (lumbar) | Regression analysis | Insulin | Hip | Body mass index | Hyperglycemia | Bone mass | Computed tomography | Collagen | Ultrasound | Metabolic disorders | Smoking | Clinical Medicine | Other Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Annan klinisk medicin | Klinisk medicin
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20. Full Text Comparisons of Immunoassay and Mass Spectrometry Measurements of Serum Estradiol Levels and Their Influence on Clinical Association Studies in Men
by Ohlsson, Claes and Nilsson, Maria E and Tivesten, Åsa and Ryberg, Henrik and Mellström, Dan and Karlsson, M. K and Ljunggren, O and Labrie, F and Orwoll, E. S and Lee, D. M and Pye, S. R and O'Neill, T. W and Finn, J. D and Adams, J. E and Ward, K. A and Boonen, S and Bartfai, G and Casanueva, F. F and Forti, G and Giwercman, A and Han, T. S and Huhtaniemi, I. T and Kula, K and Lean, M. E. J and Pendleton, N and Punab, M and Vanderschueren, D and Wu, F. C. W and Vandenput, Liesbeth and Wallenberg Laboratory and Institute of Medicine and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Institute of Neuroscience and Physiology and Göteborgs universitet and Gothenburg University and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition and Wallenberglaboratoriet and Institutionen för medicin and Institutionen för neurovetenskap och fysiologi
Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 2013, Volume 98, Issue 6, p. E1097
Context: Immunoassay-based techniques, routinely used to measure serum estradiol (E2), are known Objective: Our objective was to compare immunoassay and MS... 
middle-aged men | testosterone | peripheral arterial-disease | assays | Klinisk medicin | sex-hormones | Clinical Medicine | reactive protein-levels | Endokrinologi och diabetes | sweden | elderly-men | risk | mros | Endocrinology and Diabetes
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