Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (17) 17
life sciences & biomedicine (13) 13
chemistry (10) 10
humans (9) 9
animals (8) 8
organic chemistry (8) 8
acyclic or carbocyclic compounds (6) 6
human necessities (6) 6
hygiene (6) 6
male (6) 6
medical or veterinary science (6) 6
metallurgy (6) 6
specific therapeutic activity of chemical compounds ormedicinal preparations (6) 6
biochemistry & molecular biology (5) 5
heterocyclic compounds (5) 5
mice (5) 5
preparations for medical, dental, or toilet purposes (5) 5
biological and medical sciences (3) 3
dairy cattle (3) 3
female (3) 3
lipids (3) 3
methyltransferases - metabolism (3) 3
milk production (3) 3
molecular structure (3) 3
multidisciplinary sciences (3) 3
physical sciences (3) 3
science & technology - other topics (3) 3
sterols - chemistry (3) 3
acetylation (2) 2
acetylieren (2) 2
agriculture (2) 2
agriculture, dairy & animal science (2) 2
analysis (2) 2
anti-bacterial agents - administration & dosage (2) 2
behaviour (2) 2
biochemistry (2) 2
biosynthesis (2) 2
chemistry, multidisciplinary (2) 2
child (2) 2
cholesterol (2) 2
chromatin (2) 2
cystic fibrosis - complications (2) 2
drug delivery systems (2) 2
drug development (2) 2
drug discovery (2) 2
enterobacter cloacae - growth & development (2) 2
enterobacter cloacae - metabolism (2) 2
fundamental and applied biological sciences. psychology (2) 2
gen (2) 2
gene expression (2) 2
hek293 cells (2) 2
histone acetyltransferases - antagonists & inhibitors (2) 2
histone acetyltransferases - genetics (2) 2
histones (2) 2
home infusion therapy - adverse effects (2) 2
home infusion therapy - methods (2) 2
housing systems (2) 2
infusions, intravenous (2) 2
inhibitors (2) 2
leukemia (2) 2
maus (2) 2
methylation (2) 2
mice, inbred c57bl (2) 2
microbiology (2) 2
models, molecular (2) 2
molecular biology (2) 2
molybdenum (2) 2
nitrate reductase (2) 2
opportunistic infections - complications (2) 2
opportunistic infections - drug therapy (2) 2
oxidation-reduction (2) 2
oxidoreductases - metabolism (2) 2
parents - education (2) 2
patient selection (2) 2
physiological aspects (2) 2
polycyclic compounds (2) 2
protozoan proteins - metabolism (2) 2
research article (2) 2
research articles (2) 2
respiratory tract infections - complications (2) 2
respiratory tract infections - drug therapy (2) 2
selenic acid (2) 2
selenium (2) 2
selenium compounds - metabolism (2) 2
stem cells (2) 2
sterol 14-demethylase - metabolism (2) 2
sterols (2) 2
synthesis (2) 2
temperature (2) 2
transcription (2) 2
transferases (2) 2
trypanosoma brucei brucei - drug effects (2) 2
trypanosoma brucei brucei - metabolism (2) 2
14-alpha demethylase inhibitors - chemical synthesis (1) 1
14-alpha demethylase inhibitors - chemistry (1) 1
14-alpha demethylase inhibitors - therapeutic use (1) 1
8-lophenol (1) 1
acetylation - drug effects (1) 1
activity (1) 1
administration, oral (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Synthesis and Biological Activity of Sterol 14α-Demethylase and Sterol C24-Methyltransferase Inhibitors
by Leaver, David J
Molecules (Basel, Switzerland), ISSN 1420-3049, 07/2018, Volume 23, Issue 7, p. 1753
synthesis | mechanism-based inactivators | azoles | antiparasitic drugs | Chagas disease | human African trypanosomiasis | antifungals | sterol 14α-demethylase | sterol C24-methyltransferase | sterol biosynthesis | Fungal Proteins - chemistry | Methyltransferases - chemistry | 14-alpha Demethylase Inhibitors - chemistry | Protozoan Proteins - antagonists & inhibitors | Humans | Methyltransferases - metabolism | Fungal Proteins - antagonists & inhibitors | Mycoses - enzymology | 14-alpha Demethylase Inhibitors - chemical synthesis | Protozoan Infections - drug therapy | Animals | Methyltransferases - antagonists & inhibitors | Protozoan Proteins - metabolism | Mycoses - drug therapy | Protozoan Proteins - chemistry | Sterol 14-Demethylase - metabolism | 14-alpha Demethylase Inhibitors - therapeutic use | Sterol 14-Demethylase - chemistry | Fungal Proteins - metabolism | Protozoan Infections - enzymology | Vector-borne diseases | Protozoa | Ergosterol | Methyltransferase | Biosynthesis | Leishmaniasis | Metabolism | Drug development | Biological activity | Tropical diseases | Fungi | Inhibitors | Sterols | Chagas' disease | African trypanosomiasis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells
by Santori, Fabio R and Huang, Pengxiang and van de Pavert, Serge A and Douglass, Eugene F and Leaver, David J and Haubrich, Brad A and Keber, Rok and Lorbek, Gregor and Konijn, Tanja and Rosales, Brittany N and Rozman, Damjana and Horvat, Simon and Rahier, Alain and Mebius, Reina E and Rastinejad, Fraydoon and Nes, W. David and Littman, Dan R
Cell metabolism, ISSN 1550-4131, 02/2015, Volume 21, Issue 2, pp. 286 - 298
Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Lymphocytes - metabolism | Cell Line | Sterols - metabolism | Sterols - chemistry | Humans | Drosophila melanogaster - cytology | Male | Mice, Transgenic | Mice, Knockout | Sterol 14-Demethylase - deficiency | Animals | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | HEK293 Cells | Ligands | Mice | Sterol 14-Demethylase - metabolism | Th17 Cells | Cholesterol - biosynthesis | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth
by Baell, Jonathan B and Leaver, David J and Hermans, Stefan J and Kelly, Gemma L and Brennan, Margs S and Downer, Natalie L and Nguyen, Nghi and Wichmann, Johannes and McRae, Helen M and Yang, Yuqing and Cleary, Ben and Lagiakos, H. Rachel and Mieruszynski, Stephen and Pacini, Guido and Vanyai, Hannah K and Bergamasco, Maria I and May, Rose E and Davey, Bethany K and Morgan, Kimberly J and Sealey, Andrew J and Wang, Beinan and Zamudio, Natasha and Wilcox, Stephen and Garnham, Alexandra L and Sheikh, Bilal N and Aubrey, Brandon J and Doggett, Karen and Chung, Matthew C and de Silva, Melanie and Bentley, John and Pilling, Pat and Hattarki, Meghan and Dolezal, Olan and Dennis, Matthew L and Falk, Hendrik and Ren, Bin and Charman, Susan A and White, Karen L and Rautela, Jai and Newbold, Andrea and Hawkins, Edwin D and Johnstone, Ricky W and Huntington, Nicholas D and Peat, Thomas S and Heath, Joan K and Strasser, Andreas and Parker, Michael W and Smyth, Gordon K and Street, Ian P and Monahan, Brendon J and Voss, Anne K and Thomas, Tim
Nature (London), ISSN 0028-0836, 08/2018, Volume 560, Issue 7717, pp. 253 - 257
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Histone Acetyltransferases - deficiency | Histones - chemistry | Mice, Inbred C57BL | Cells, Cultured | Cellular Senescence - drug effects | Histone Acetyltransferases - genetics | Lymphoma - genetics | Models, Molecular | Male | Acetylation - drug effects | Lymphoma - drug therapy | Animals | Histone Acetyltransferases - antagonists & inhibitors | Fibroblasts | Lymphoma - enzymology | Lymphoma - pathology | Cell Proliferation - drug effects | Lysine - metabolism | Mice | Drug Development | Gene Expression Regulation, Neoplastic - drug effects | Histones - metabolism | Lysine - chemistry | Analysis | Transferases | Oncology, Experimental | Histones | Physiological aspects | Acetylation | Research | Gene expression | Tumors | Cancer | Chromatin | Senescence | Transcription | Leukemia | DNA damage | Hepatocellular carcinoma | Myc protein | Drug development | Proteins | Cell cycle | Coenzyme A | Cyclin-dependent kinase inhibitors | Deoxyribonucleic acid--DNA | Zebrafish | INK4 protein | Bioavailability | Lymphoma | Suppressors | Chromosome translocations | Inhibitors | Lysine | Stem cells | Kinetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text HBO1 is required for the maintenance of leukaemia stem cells
by MacPherson, Laura and Anokye, Juliana and Yeung, Miriam M and Lam, Enid Y. N and Chan, Yih-Chih and Weng, Chen-Fang and Yeh, Paul and Knezevic, Kathy and Butler, Miriam S and Hoegl, Annabelle and Chan, Kah-Lok and Burr, Marian L and Gearing, Linden J and Willson, Tracy and Liu, Joy and Choi, Jarny and Yang, Yuqing and Bilardi, Rebecca A and Falk, Hendrik and Nghi Nguyen and Stupple, Paul A and Peat, Thomas S and Zhang, Ming and de Silva, Melanie and Carrasco-Pozo, Catalina and Avery, Vicky M and Khoo, Poh Sim and Dolezal, Olan and Dennis, Matthew L and Nuttall, Stewart and Surjadi, Regina and Newman, Janet and Ren, Bin and Leaver, David J and Sun, Yuxin and Baell, Jonathan B and Dovey, Oliver and Vassiliou, George S and Grebien, Florian and Dawson, Sarah-Jane and Street, Ian P and Monahan, Brendon J and Burns, Christopher J and Choudhary, Chunaram and Blewitt, Marnie E and Voss, Anne K and Thomas, Tim and Dawson, Mark A
Nature (London), ISSN 0028-0836, 01/2020, Volume 577, Issue 7789, pp. 266 - 270
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein Structure, Tertiary | Histone Acetyltransferases - chemistry | Humans | Leukemia, Myeloid, Acute - metabolism | Mice, Inbred C57BL | Histone Acetyltransferases - genetics | Models, Molecular | Animals | Neoplastic Stem Cells - metabolism | Histone Acetyltransferases - metabolism | Cell Line, Tumor | Mice | Leukemia, Myeloid, Acute - genetics | Epigenetic inheritance | Chromatin | RNA | Analysis | Stem cells | Histones | Biotechnology industry | Transcriptional coactivators | Control | Usage | Chemical properties | Acetylation | Methods | Regulators | Transcription | Leukemia | Genes | Clinical trials | Stem cell transplantation | MYST acetyltransferase | DNA-directed RNA polymerase | Population | CRISPR | Therapeutic applications | Mass spectroscopy | RNA polymerase | Maintenance | Gene expression | Histone acetyltransferase | Domains | Organic chemistry | HBO1 protein | Cell lines | Epigenetics | Mass spectrometry | RNA polymerase II | Histone H3 | Apoptosis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Enterobacter cloacae SLD1a-1 gains a selective advantage from selenate reduction when growing in nitrate-depleted anaerobic environments
by Leaver, James T and Richardson, David J and Butler, Clive S
Journal of industrial microbiology & biotechnology, ISSN 1367-5435, 8/2008, Volume 35, Issue 8, pp. 867 - 873
Biochemistry, general | Electron transport chain | Biotechnology | Chemistry | Bioreactor | Genetic Engineering | Nitrate | Microbiology | Microbial Genetics and Genomics | Terminal electron acceptor | Selenate | Bioinformatics | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Methods. Procedures. Technologies | Bioreactors | Various methods and equipments | Anaerobiosis | Selenic Acid | Nitrates - metabolism | Enterobacter cloacae - growth & development | Selenium - metabolism | Enterobacter cloacae - metabolism | Oxidation-Reduction | Oxidoreductases - metabolism | Models, Biological | Bacterial Proteins - metabolism | Selenium Compounds - metabolism | Microbial Viability | Catalysis | Selenium | Studies | Chemical reactors | Bioremediation | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text X-Ray Crystal Structure Determinations of Galactosylacetylene Building Blocks
by Leaver, David J and Hughes, Andrew B and Polyzos, Anastasios and White, Jonathan M
Journal of carbohydrate chemistry, ISSN 0732-8303, 11/2010, Volume 29, Issue 8-9, pp. 379 - 385
X-ray crystal structure | Synthesis | Structure | Galactosylacetylene | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Science & Technology | Biochemistry | Crystal structure | Carbohydrates | Ionizing radiation | Reviews
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Herbage intake handbook
by Leaver, J. D and British Grassland Society
1982, ISBN 0905944062, vi, 143
Cattle | Alimentation | Bovins | Efficacité | Feed utilization efficiency | Pâturages | Grazing | Feeding and feeds
Book
Details down arrow
8. Full Text Pharmacokinetics of oral cyclosporine (Neoral) in heart transplant recipients during the immediate period after surgery
by Banner, Nicholas R and David, Olivier J and Leaver, Neil and Davis, Julie and Breen, Jane and Johnston, Atholl and Yacoub, Magdi H
Transplant international, ISSN 0934-0874, 12/2002, Volume 15, Issue 12, pp. 649 - 654
Heart transplant Cyclosporine Pharmacokinetics Therapeutic drug monitoring | Transplantation | Life Sciences & Biomedicine | Surgery | Science & Technology | Biological and medical sciences | Medical sciences | Immunomodulators | Pharmacology. Drug treatments | Colorimetry - methods | Heart Transplantation - immunology | Administration, Oral | Area Under Curve | Humans | Immunosuppressive Agents - pharmacokinetics | Immunosuppressive Agents - therapeutic use | Middle Aged | Postoperative Period | Male | Metabolic Clearance Rate | Cyclosporine - blood | Cyclosporine - therapeutic use | Immunosuppressive Agents - blood | Cyclosporine - administration & dosage | Heart Transplantation - physiology | Cyclosporine - pharmacokinetics | Monitoring, Intraoperative - methods | Adult | Female | Continental Population Groups | Immunosuppressive Agents - administration & dosage | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text A nematode sterol C4 alpha-methyltransferase catalyzes a new methylation reaction responsible for sterol diversity
by Zhou, Wenxu and Fisher, Paxtyn M and Vanderloop, Boden H and Shen, Yun and Shi, Huazhong and Maldonado, Adrian J and Leaver, David J and Nes, W. David
Journal of lipid research, ISSN 0022-2275, 02/2020, Volume 61, Issue 2, pp. 192 - 204
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Animals | Biocatalysis | Caenorhabditis elegans - growth & development | Sterols - chemistry | Methyltransferases - metabolism | Methylation | Sterols - biosynthesis | Caenorhabditis elegans - enzymology | Index Medicus | 8-lophenol | Caenorhabditis elegans • biosynthesis | evolution
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Synthesis and Biological Activity of Sterol 14-Demethylase and Sterol C24-Methyltransferase Inhibitors
by Leaver, David J
Molecules (Basel, Switzerland), ISSN 1420-3049, 07/2018, Volume 23, Issue 7
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Discovery of an ergosterol-signaling factor that regulates trypanosoma brucei growth
by Haubrich, Brad A and Singha, Ujjal K and Miller, Matthew B and Nes, Craigen R and Anyatonwu, Hosanna and Lecordier, Laurence and Patkar, Presheet and Leaver, David J and Villalta, Fernando and Vanhollebeke, Benoit and Chaudhuri, Minu and Nes, W. David
Journal of lipid research, ISSN 0022-2275, 02/2015, Volume 56, Issue 2, pp. 331 - 341
Knockdown | Ribonucleic acid interference | Anti-parasite drugs | Sparking function | Inhibitor | Ergosterol biosynthesis | Cholesterol | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Ergosterol - metabolism | Trypanosoma brucei brucei - metabolism | Methyltransferases - metabolism | Methyltransferases - genetics | Male | Cholesterol - metabolism | Protozoan Proteins - genetics | Trypanosoma brucei brucei - drug effects | Itraconazole - pharmacology | Animals | Protozoan Proteins - metabolism | RNA - pharmacology | Mice | Mice, Inbred BALB C | Index Medicus | s | inhibitor | knockdown | sparking function | cholesterol | anti-parasite drugs | ergosterol biosynthesis | ribonucleic acid interference
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A
by Leaver, David J and Cleary, Benjamin and Nguyen, Nghi and Priebbenow, Daniel L and Lagiakos, H. Rachel and Sanchez, Julie and Xue, Lian and Huang, Fei and Sun, Yuxin and Mujumdar, Prashant and Mudududdla, Ramesh and Varghese, Swapna and Teguh, Silvia and Charman, Susan A and White, Karen L and Katneni, Kasiram and Cuellar, Matthew and Strasser, Jessica M and Dahlin, Jayme L and Walters, Michael A and Street, Ian P and Monahan, Brendon J and Jarman, Kate E and Sabroux, Helene Jousset and Falk, Hendrik and Chung, Matthew C and Hermans, Stefan J and Parker, Michael W and Thomas, Tim and Baell, Jonathan B
Journal of medicinal chemistry, ISSN 0022-2623, 08/2019, Volume 62, Issue 15, pp. 7146 - 7159
Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights