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Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2013, Volume 190, Issue 5, pp. 2362 - 2371
We showed that IgA induces IL-10 in monocytes and dendritic cells. Because reciprocal inhibition exists between IL-10 and IL-12, we explored whether IgA could... 
TRANSCRIPTION FACTORS | ACTIVATED PROTEIN-KINASE | INTERFERON-GAMMA | INTERLEUKIN-12 PRODUCTION | NITRIC-OXIDE SYNTHASE | GENE-EXPRESSION | RECEPTOR LIGATION | IMMUNOLOGY | NF-KAPPA-B | TERMINAL KINASE | SIGNAL TRANSDUCER | Antigens, CD - immunology | I-kappa B Proteins - immunology | Interleukin-12 - genetics | Monocytes - cytology | Dendritic Cells - immunology | Humans | Monocytes - immunology | Antigens, CD - genetics | I-kappa B Proteins - genetics | Receptors, IgG - genetics | Flow Cytometry | Interleukin-12 - antagonists & inhibitors | Chemokine CXCL10 - immunology | Dendritic Cells - drug effects | Phosphorylation - drug effects | Interleukin-12 - biosynthesis | NF-KappaB Inhibitor alpha | Cells, Cultured | Chemokine CXCL10 - antagonists & inhibitors | Immunoglobulin A - pharmacology | Receptors, IgG - immunology | STAT1 Transcription Factor - genetics | STAT1 Transcription Factor - immunology | Gene Expression Regulation - drug effects | Monocytes - drug effects | Receptors, Fc - immunology | Signal Transduction - drug effects | Chemokine CXCL10 - genetics | Immunoglobulin A - immunology | Interferon-gamma - immunology | Interleukin-10 - antagonists & inhibitors | Interleukin-10 - genetics | Interleukin-12 - immunology | Lipopolysaccharides - pharmacology | Receptors, Fc - genetics | Dendritic Cells - cytology | Interleukin-10 - immunology | Interferon-gamma - pharmacology | Index Medicus | Abridged Index Medicus
Journal Article
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, ISSN 1073-449X, 03/2019, Volume 199, Issue 5, pp. 592 - 602
Rationale: Accumulation of B cells and lymphoid follicles (LFs) has been described in chronic obstructive pulmonary disease (COPD) airways, but the functional... 
IMMUNITY | IgA | NEOGENESIS | B lymphocytes | SMALL AIRWAYS | RECEPTOR | lymphoid follicles | CXCL13 | B-CELLS | EPITHELIUM | CELL-ACTIVATING FACTOR | RESPIRATORY SYSTEM | INFLAMMATION | COPD | CRITICAL CARE MEDICINE | Immunoglobulins | Tobacco smoke | Dendritic cells | Cytokines | Lung cancer | Lung diseases | Infections | Cigarettes | Lymphocytes | Surgery | Ligands | Chronic obstructive pulmonary disease | Smoking
Journal Article
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 01/2017, Volume 12, Issue 1, p. S713
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 01/2017, Volume 12, Issue 1, pp. S713 - S713
Journal Article
Clinical Immunology, ISSN 1521-6616, 2015, Volume 168, pp. 37 - 46
Abstract We aimed to study whether IgA or IgG could modulate dendritic cells through the Notch pathway. Blood myeloid DC were isolated from controls or... 
Allergy and Immunology | DLL4 | Notch ligand | IgG | IgA | Myeloid dendritic cells | TH2 IMMUNITY | FC-GAMMA RECEPTORS | NOTCH LIGANDS | ALLERGIC RHINITIS | INDUCTION | IMMUNOLOGY | HUMAN MONOCYTES | RESPONSES | DISEASE | REGULATORY T-CELLS | ALPHA-RI | Rhinitis, Allergic - genetics | Receptors, Notch - metabolism | Rhinitis, Allergic - immunology | Coculture Techniques | Dendritic Cells - immunology | Humans | Middle Aged | Male | Rhinitis, Allergic - metabolism | Th2 Cells - immunology | Th1 Cells - immunology | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Signal Transduction - immunology | Flow Cytometry | Immunoglobulin G - immunology | Gene Expression - immunology | Adult | Female | Dendritic Cells - metabolism | Cytokines - immunology | Immunoglobulin A - metabolism | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | CD4-Positive T-Lymphocytes - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Th2 Cells - metabolism | Models, Immunological | Immunoglobulin A - immunology | Aged | Intercellular Signaling Peptides and Proteins - immunology | Receptors, Notch - immunology | Dendritic cells | T cells | Immunoglobulin A | Immunoglobulin G | Antigens | Index Medicus
Journal Article
EUROPEAN RESPIRATORY JOURNAL, ISSN 0903-1936, 09/2016, Volume 48, Issue suppl 60, p. PA3992
Conference Proceeding
Clinical and Translational Allergy, ISSN 2045-7022, 07/2013, Volume 3, Issue S2, pp. O8 - O8
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 09/2014, Volume 190, Issue 5, p. 509
The generation of protective secretory IgA relies on the epithelial polymeric immunoglobulin receptor (pIgR). pIgR expression is reduced in chronic obstructive... 
Journal Article
Molecular cancer therapeutics, ISSN 1535-7163, 01/2019, Volume 18, Issue 1, pp. 17 - 27
Small cell lung cancer (SCLC) has a poor prognosis. Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase regulating cell proliferation, survival,... 
UNITED-STATES | SURVIVAL | ACTIVATION | TYROSINE PHOSPHORYLATION | ONCOLOGY | SAFETY | GROWTH | FAK INHIBITOR | PROLIFERATION | V-SRC | TRENDS | PF-573,228 | FRNK | Rac1 | small cell lung cancer | FAK inhibition | FAK shRNA
Journal Article
Journal Article
EUROPEAN RESPIRATORY JOURNAL, ISSN 0903-1936, 09/2015, Volume 46, Issue suppl 59, p. PA5104
Conference Proceeding
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 12/2011, Volume 184, Issue 11, p. 1270
There is evidence that CD4(+) effector T lymphocytes (T eff) participate in the development of lung fibrosis, but the role of their CD4(+) regulatory T-cell (T... 
Journal Article
American journal of respiratory and critical care medicine, 10/2018
Accumulation of B cells and lymphoid follicles (LF) has been described in chronic obstructive pulmonary disease (COPD) airways, but the functional status of... 
Journal Article
Toxicology Letters, ISSN 0378-4274, 09/2009, Volume 189, pp. S45 - S45
Journal Article
Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, ISSN 1871-5222, 2010, Volume 10, Issue 3, pp. 123 - 141
Several epidemiological, pathophysiologic and clinical data demonstrate the interrelationship between upper and lower airways, and common features between... 
Mucosal immunity | Airway inflammation | Lower airway | Chronic respiratory disease | Upper airway
Journal Article
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