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1. Full Text Use of low dose rVSV-ZEBOV: safety issues in a Swiss cohort
by Ledgerwood, Julie E
The Lancet infectious diseases, ISSN 1473-3099, 2015, Volume 15, Issue 10, pp. 1117 - 1119
Infectious Disease | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Vaccination - methods | Hemorrhagic Fever, Ebola - prevention & control | Humans | Ebola Vaccines - administration & dosage | Ebola Vaccines - immunology | Female | Male | Vaccination - adverse effects | Ebola virus | Antigens | Arthritis | Vaccines | Dermatitis | Investigations | Index Medicus
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2. Full Text Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial
by Chang, Lee-Jah, MD and Dowd, Kimberly A, PhD and Mendoza, Floreliz H, RN and Saunders, Jamie G, BSN and Sitar, Sandra, MSc and Plummer, Sarah H, NP and Yamshchikov, Galina, MSc and Sarwar, Uzma N, MD and Hu, Zonghui, PhD and Enama, Mary E, PA-C and Bailer, Robert T, PhD and Koup, Richard A, MD and Schwartz, Richard M, PhD and Akahata, Wataru, PhD and Nabel, Gary J, MD and Mascola, John R, MD and Pierson, Theodore C, PhD and Graham, Barney S, MD and Ledgerwood, Julie E, Dr and the VRC 311 Study Team and VRC 311 Study Team
The Lancet (British edition), ISSN 0140-6736, 2014, Volume 384, Issue 9959, pp. 2046 - 2052
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antibodies, Neutralizing - analysis | Enzyme-Linked Immunosorbent Assay | Humans | Middle Aged | Vaccination | Adolescent | Immune Tolerance | Adult | Female | Male | Chikungunya virus - immunology | Viral Vaccines - administration & dosage | Clinical trials | Viruses | Biomedical research | Vaccines | Viral infections | Immune system | Index Medicus | Abridged Index Medicus
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3. Full Text Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin
by Andrews, Sarah F and Chambers, Michael J and Schramm, Chaim A and Plyler, Jason and Raab, Julie E and Kanekiyo, Masaru and Gillespie, Rebecca A and Ransier, Amy and Darko, Sam and Hu, Jianfei and Chen, Xuejun and Yassine, Hadi M and Boyington, Jeffrey C and Crank, Michelle C and Chen, Grace L and Coates, Emily and Mascola, John R and Douek, Daniel C and Graham, Barney S and Ledgerwood, Julie E and McDermott, Adrian B
Immunity (Cambridge, Mass.), ISSN 1074-7613, 08/2019, Volume 51, Issue 2, pp. 398 - 410.e5
influenza | Ig repertoire | hemagglutinin | activated B cells | Tbet | H7N9 | memory B cells | vaccine response | Life Sciences & Biomedicine | Immunology | Science & Technology | Influenza A Virus, H7N9 Subtype - physiology | Antibodies, Viral - metabolism | Lymphocyte Activation | Humans | Middle Aged | Vaccination | Cells, Cultured | Male | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Epitopes - immunology | Young Adult | Phenotype | B-Lymphocytes - immunology | Influenza Vaccines - immunology | Antibody Formation | Adult | B-Lymphocyte Subsets - immunology | Female | Immunologic Memory | Receptors, Antigen, B-Cell - genetics | Single-Cell Analysis | Influenza, Human - immunology | Influenza vaccines | Medical research | Analysis | Communicable diseases | Influenza | Lectins | Medicine, Experimental | B cells | Antigenic determinants | Flow cytometry | Antigens | Phenotypes | Immunological memory | Immunoglobulins | Memory cells | Statistical analysis | Pandemics | Clinical trials | Viruses | Vaccines | Epitopes | Immunity | Cell activation | Lymphocytes B | Hemagglutinins | Evolution | Influenza A | Kinetics | Biosensors | Human behavior | Binding sites | Index Medicus
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4. Full Text Zika Virus Vaccine Development: Progress in the Face of New Challenges
by Diamond, Michael S and Ledgerwood, Julie E and Pierson, Theodore C
Annual review of medicine, ISSN 0066-4219, 1/2019, Volume 70, Issue 1, pp. 121 - 135
ZIKV | vaccine | antibody | neutralization | dengue virus | Zika virus | antibody-dependent enhancement | flavivirus | Zika Virus - immunology | Humans | Male | Forecasting | Antibodies, Neutralizing - immunology | Animals | Zika Virus Infection - epidemiology | Communicable Diseases, Emerging - prevention & control | Disease Outbreaks | Zika Virus Infection - immunology | Female | Viral Envelope Proteins - immunology | Drug Development | Zika Virus Infection - prevention & control | Viral Vaccines - immunology | Zika Virus - pathogenicity | Medical colleges | Medical research | Analysis | Immunotherapy | Communicable diseases | Dengue viruses | Medicine, Experimental | Vaccines | Research | Vector-borne diseases | Epidemics | Immunization | Animal models | Congenital defects | Pathogenesis | Viruses | Disease control | Pregnancy | Microencephaly | Public health | Index Medicus
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5. Full Text Chimpanzee Adenovirus Vector Ebola Vaccine
by Ledgerwood, Julie E and DeZure, Adam D and Stanley, Daphne A and Coates, Emily E and Novik, Laura and Enama, Mary E and Berkowitz, Nina M and Hu, Zonghui and Joshi, Gyan and Ploquin, Aurélie and Sitar, Sandra and Gordon, Ingelise J and Plummer, Sarah A and Holman, LaSonji A and Hendel, Cynthia S and Yamshchikov, Galina and Roman, Francois and Nicosia, Alfredo and Colloca, Stefano and Cortese, Riccardo and Bailer, Robert T and Schwartz, Richard M and Roederer, Mario and Mascola, John R and Koup, Richard A and Sullivan, Nancy J and Graham, Barney S and VRC 207 Study Team
The New England journal of medicine, ISSN 0028-4793, 03/2017, Volume 376, Issue 10, pp. 928 - 938
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | T-Lymphocytes - physiology | Hemorrhagic Fever, Ebola - prevention & control | Humans | Middle Aged | Ebola Vaccines - administration & dosage | Male | Pan troglodytes | Antibodies, Viral - blood | Ebola Vaccines - adverse effects | Ebolavirus - immunology | Glycoproteins - immunology | Animals | Fever - etiology | Adult | Ebola Vaccines - immunology | Adenoviruses, Simian | Genetic Vectors | Antibodies, Neutralizing - blood | Ebola virus infections | Care and treatment | Usage | Vaccines | Health care | Epidemics | Antigens | Immune response | CD8 antigen | Vaccination | Clinical trials | Glycoproteins | Lymphocytes T | Fever | Antibody response | CD4 antigen | Ebola virus | Immunogenicity | Pharmaceutical industry | Index Medicus | Abridged Index Medicus
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6. Full Text DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials
by Ledgerwood, Julie E, DO and Wei, Chih-Jen, PhD and Hu, Zonghui, PhD and Gordon, Ingelise J, RN and Enama, Mary E, PA-C and Hendel, Cynthia S, CRNP and McTamney, Patrick M, PhD and Pearce, Melissa B, PhD and Yassine, Hadi M, PhD and Boyington, Jeffrey C, PhD and Bailer, Robert, PhD and Tumpey, Terrence M, PhD and Koup, Richard A, MD and Mascola, John R, MD and Nabel, Gary J, MD and Graham, Barney S, MD and the VRC 306 Study Team and VRC 306 Study Team
The Lancet infectious diseases, ISSN 1473-3099, 2011, Volume 11, Issue 12, pp. 916 - 924
Infectious Disease | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Biological and medical sciences | Viral diseases of the respiratory system and ent viral diseases | Infectious diseases | Medical sciences | Human viral diseases | Viral diseases | Cytokines - metabolism | Humans | Middle Aged | Vaccines, DNA - immunology | Influenza A Virus, H5N1 Subtype - genetics | Young Adult | Vaccines, Inactivated - immunology | Influenza Vaccines - immunology | Influenza Vaccines - genetics | Influenza A Virus, H5N1 Subtype - immunology | Adolescent | Adult | Antibodies, Viral - immunology | Influenza, Human - prevention & control | Cytokines - immunology | Influenza vaccines | Clinical trials | Influenza | DNA | Index Medicus | Cytokines | Antibodies | Lymphocytes T | Vaccines | Immunity | Infection | Immunogenicity | Age | Enzyme-linked immunosorbent assay | Immunoassays
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7. Full Text Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial
by Kibuuka, Hannah, MMed and Berkowitz, Nina M, MPH and Millard, Monica, MPH and Enama, Mary E, MA and Tindikahwa, Allan, MPH and Sekiziyivu, Arthur B, MSc and Costner, Pamela, BSN and Sitar, Sandra, MS and Glover, Deline, BS and Hu, Zonghui, PhD and Joshi, Gyan, MPH and Stanley, Daphne, MS and Kunchai, Meghan, MPH and Eller, Leigh Anne, PhD and Bailer, Robert T, PhD and Koup, Richard A, MD and Nabel, Gary J, MD and Mascola, John R, MD and Sullivan, Nancy J, PhD and Graham, Barney S, MD and Roederer, Mario, PhD and Michael, Nelson L, MD and Robb, Merlin L, MD and Ledgerwood, Julie E, Dr and the RV 247 Study Team and RV 247 Study Team
The Lancet (British edition), ISSN 0140-6736, 2015, Volume 385, Issue 9977, pp. 1545 - 1554
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Double-Blind Method | Humans | Vaccines, DNA - immunology | Ebola Vaccines - administration & dosage | Male | Antibodies, Viral - blood | Ebola Vaccines - adverse effects | Vaccines, DNA - administration & dosage | Ebolavirus - immunology | Viral Fusion Proteins - immunology | Young Adult | Vaccines, DNA - adverse effects | Adolescent | Intention to Treat Analysis | Marburgvirus - immunology | Adult | Ebola Vaccines - immunology | Female | Uganda | Ebola virus | Medical research | DNA | Clinical trials | Medicine, Experimental | Glycoproteins | Vaccines | Marburg virus disease | Immunization | Public health | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus
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8. Full Text Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody
by Corti, Davide and Misasi, John and Mulangu, Sabue and Stanley, Daphne A and Kanekiyo, Masaru and Wollen, Suzanne and Ploquin, Aurélie and Doria-Rose, Nicole A and Staupe, Ryan P and Bailey, Michael and Shi, Wei and Choe, Misook and Marcus, Hadar and Thompson, Emily A and Cagigi, Alberto and Silacci, Chiara and Fernandez-Rodriguez, Blanca and Perez, Laurent and Sallusto, Federica and Vanzetta, Fabrizia and Agatic, Gloria and Cameroni, Elisabetta and Kisalu, Neville and Gordon, Ingelise and Ledgerwood, Julie E and Mascola, John R and Graham, Barney S and Muyembe-Tamfun, Jean-Jacques and Trefry, John C and Lanzavecchia, Antonio and Sullivan, Nancy J
Science (American Association for the Advancement of Science), ISSN 0036-8075, 03/2016, Volume 351, Issue 6279, pp. 1339 - 1342
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antibodies, Neutralizing - administration & dosage | Hemorrhagic Fever, Ebola - prevention & control | Humans | Survivors | Molecular Sequence Data | Male | Clinical Trials as Topic | Antibodies, Monoclonal - isolation & purification | Hemorrhagic Fever, Ebola - epidemiology | Ebolavirus - immunology | Antibodies, Viral - isolation & purification | Antibodies, Neutralizing - isolation & purification | Antibodies, Neutralizing - immunology | Animals | Antibodies, Monoclonal - administration & dosage | Disease Outbreaks | Adult | Antibodies, Viral - immunology | Female | Macaca | Antibodies, Viral - administration & dosage | Antibodies, Monoclonal - immunology | Virus diseases | Monoclonal antibodies | Physiological aspects | Ebola virus infections | Care and treatment | Health aspects | Ebola virus | Drug therapy | Index Medicus
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9. Full Text AS03-adjuvanted influenza vaccine in elderly people
by Ledgerwood, Julie E
The Lancet infectious diseases, ISSN 1473-3099, 06/2013, Volume 13, Issue 6, pp. 466 - 467
Influenza Vaccines - administration & dosage | alpha-Tocopherol - administration & dosage | Adjuvants, Immunologic - administration & dosage | Humans | Male | Squalene - administration & dosage | Polysorbates - administration & dosage | Female | Influenza A virus - immunology | Influenza B virus - immunology | Influenza, Human - prevention & control | Drug Combinations | Influenza, Human - immunology | Index Medicus
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10. Full Text Structural and molecular basis for Ebola virus neutralization by protective human antibodies
by Misasi, John and Gilman, Morgan S. A and Kanekiyo, Masaru and Gui, Miao and Cagigi, Alberto and Mulangu, Sabue and Corti, Davide and Ledgerwood, Julie E and Lanzavecchia, Antonio and Cunningham, James and Muyembe-Tamfun, Jean Jacques and Baxa, Ulrich and Graham, Barney S and Xiang, Ye and Sullivan, Nancy J and McLellan, Jason S and Argonne National Lab. (ANL), Argonne, IL (United States)
Science (American Association for the Advancement of Science), ISSN 0036-8075, 03/2016, Volume 351, Issue 6279, pp. 1343 - 1346
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cathepsins - chemistry | Hemorrhagic Fever, Ebola - prevention & control | Humans | Crystallography, X-Ray | Ebolavirus - immunology | Cryoelectron Microscopy | Antibodies, Neutralizing - immunology | Proteolysis | Antibodies, Neutralizing - chemistry | Viral Envelope Proteins - chemistry | Antibodies, Viral - chemistry | Antibodies, Viral - immunology | Protein Conformation | Viral Envelope Proteins - immunology | Hemorrhagic Fever, Ebola - immunology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Ebola virus | Physiological aspects | Monoclonal antibodies | Ebola virus infections | Research | Virus research | Molecular biology | Index Medicus | BASIC BIOLOGICAL SCIENCES
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