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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 29, pp. 13075 - 13080
Activation of the B-cell antigen receptor (BCR) signaling pathway contributes to the initiation and maintenance of B-cell malignancies and autoimmune diseases.... 
T lymphocytes | Animal models | Disease models | Gels | B lymphocytes | B cell lymphoma | Arthritis | Mice | Autoimmune diseases | Tumors | X-linked agammaglobulinemia | Lymphoma | COLLAGEN-INDUCED ARTHRITIS | THERAPY | RITUXIMAB | MULTIDISCIPLINARY SCIENCES | lymphoma | DOGS | FAMILY KINASES | BTK | RECEPTOR | DEPLETION | MICE | Arthritis, Experimental - drug therapy | Pyrazoles - therapeutic use | Humans | Benzofurans - administration & dosage | Benzofurans - pharmacology | Autoantibodies - biosynthesis | Pyrimidines - chemistry | Benzofurans - chemistry | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Lymphoma, B-Cell - enzymology | Autoimmune Diseases - drug therapy | Disease Models, Animal | Lymphoma, B-Cell - drug therapy | Pyrazoles - pharmacology | B-Lymphocytes - enzymology | Benzofurans - therapeutic use | Autoimmune Diseases - enzymology | Administration, Oral | Pyrimidines - administration & dosage | Treatment Outcome | Pyrimidines - pharmacology | Receptors, Antigen, B-Cell - immunology | B-Lymphocytes - drug effects | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Animals | B-Lymphocytes - immunology | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Dogs | Protein Kinase Inhibitors - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | Tyrosine | Cell receptors | Models | Lymphomas | Research | Properties | Biological Sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2006, Volume 281, Issue 16, pp. 11002 - 11010
Journal Article
PROTEOMICS – Clinical Applications, ISSN 1862-8346, 08/2015, Volume 9, Issue 7-8, pp. 715 - 731
Journal Article
Alzheimer's Research & Therapy, ISSN 1758-9193, 12/2018, Volume 10, Issue 1, pp. 1 - 13
Abstract Background We investigated the effect of crenezumab, a humanized anti-amyloid-beta (Aβ) immunoglobulin (Ig)G4 monoclonal antibody, on biomarkers of... 
Biomarkers | Monoclonal antibodies | Antibodies | Humanized | Alzheimer’s disease | Positron emission tomography
Journal Article
Neurology, ISSN 0028-3878, 04/2018, Volume 90, Issue 21, pp. E1889 - E1897
OBJECTIVETo evaluate the safety and efficacy of crenezumab in patients with mild to moderate Alzheimer disease (AD). METHODSIn this phase 2 trial, 431 patients... 
DEMENTIA | CLINICAL-TRIALS | A-BETA | NEURODEGENERATION | ANTIBODY | BAPINEUZUMAB | ASSESSMENT SCALE | PNEUMONIA | OLIGOMERS | CLINICAL NEUROLOGY | 322
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2010, Volume 107, Issue 29, p. 13075
  Activation of the B-cell antigen receptor (BCR) signaling pathway contributes to the initiation and maintenance of B-cell malignancies and autoimmune... 
Antigens | Biochemistry | Mutation | Kinases | Autoimmune diseases | Cells | Cancer
Journal Article
Journal Article
ALZHEIMERS RESEARCH & THERAPY, ISSN 1758-9193, 11/2018, Volume 10, Issue 1
BackgroundAmyloid- 1-42 (A(1-42)) peptide is a well-established cerebrospinal fluid (CSF) biomarker for Alzheimer's disease (AD). Reduced levels of A(1-42) are... 
Multiple-reaction monitoring (MRM) | RATIOS | Immunoassay | BETA-AMYLOID((1-42)) | ALZHEIMERS-DISEASE | QUANTIFICATION | VALIDATION | TOTAL TAU | Cerebrospinal fluid | CEREBROSPINAL-FLUID | BETA 1-42 | NEUROSCIENCES | CLINICAL NEUROLOGY | LC-MS | COLLECTION TUBES | Adsorption | Biomarkers | Amyloid | Diagnosis | Alzheimer's disease | ASSOCIATION | Preanalytical | Care and treatment | Usage | Research | Mass spectrometry
Journal Article
Alzheimer's Research and Therapy, ISSN 1758-9193, 09/2018, Volume 10, Issue 1, p. 96
Journal Article