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1. Full Text Tracking the Evolution of Non–Small-Cell Lung Cancer
by Jamal-Hanjani, Mariam and Wilson, Gareth A and McGranahan, Nicholas and Birkbak, Nicolai J and Watkins, Thomas B.K and Veeriah, Selvaraju and Shafi, Seema and Johnson, Diana H and Mitter, Richard and Rosenthal, Rachel and Salm, Max and Horswell, Stuart and Escudero, Mickael and Matthews, Nik and Rowan, Andrew and Chambers, Tim and Moore, David A and Turajlic, Samra and Xu, Hang and Lee, Siow-Ming and Forster, Martin D and Ahmad, Tanya and Hiley, Crispin T and Abbosh, Christopher and Falzon, Mary and Borg, Elaine and Marafioti, Teresa and Lawrence, David and Hayward, Martin and Kolvekar, Shyam and Panagiotopoulos, Nikolaos and Janes, Sam M and Thakrar, Ricky and Ahmed, Asia and Blackhall, Fiona and Summers, Yvonne and Shah, Rajesh and Joseph, Leena and Quinn, Anne M and Crosbie, Phil A and Naidu, Babu and Middleton, Gary and Langman, Gerald and Trotter, Simon and Nicolson, Marianne and Remmen, Hardy and Kerr, Keith and Chetty, Mahendran and Gomersall, Lesley and Fennell, Dean A and Nakas, Apostolos and Rathinam, Sridhar and Anand, Girija and Khan, Sajid and Russell, Peter and Ezhil, Veni and Ismail, Babikir and Irvin-Sellers, Melanie and Prakash, Vineet and Lester, Jason F and Kornaszewska, Malgorzata and Attanoos, Richard and Adams, Haydn and Davies, Helen and Dentro, Stefan and Taniere, Philippe and O’Sullivan, Brendan and Lowe, Helen L and Hartley, John A and Iles, Natasha and Bell, Harriet and Ngai, Yenting and Shaw, Jacqui A and Herrero, Javier and Szallasi, Zoltan and Schwarz, Roland F and Stewart, Aengus and Quezada, Sergio A and Le Quesne, John and Van Loo, Peter and Dive, Caroline and Hackshaw, Allan and Swanton, Charles and TRACERx Consortium
The New England journal of medicine, ISSN 0028-4793, 06/2017, Volume 376, Issue 22, pp. 2109 - 2121
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Lung Neoplasms - genetics | Prognosis | Prospective Studies | Carcinoma, Non-Small-Cell Lung - genetics | Lung Neoplasms - mortality | Humans | Risk Factors | Male | Phylogeny | Carcinoma, Non-Small-Cell Lung - mortality | Genetic Heterogeneity | DNA Copy Number Variations | Exome | Disease-Free Survival | Female | Neoplasm Recurrence, Local - genetics | Mutation | Chromosomal Instability | Sequence Analysis, DNA - methods | Evolution, Molecular | Lung cancer, Non-small cell | Chromosomes | Research | Medical research | Chromatin | Epidermal growth factor receptors | Transcription | p53 Protein | Lung cancer | DNA damage | Non-small cell lung carcinoma | Oncology | Genomes | Multivariate analysis | DNA repair | Survival | Cyclin-dependent kinase 4 | Genomic instability | Pathology | Census | Lungs | Evolution | Death | Tumors | Index Medicus | Abridged Index Medicus
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2. Full Text Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H 2 S Production
by Longchamp, Alban and Mirabella, Teodelinda and Arduini, Alessandro and MacArthur, Michael R and Das, Abhirup and Treviño-Villarreal, J. Humberto and Hine, Christopher and Ben-Sahra, Issam and Knudsen, Nelson H and Brace, Lear E and Reynolds, Justin and Mejia, Pedro and Tao, Ming and Sharma, Gaurav and Wang, Rui and Corpataux, Jean-Marc and Haefliger, Jacques-Antoine and Ahn, Kyo Han and Lee, Chih-Hao and Manning, Brendan D and Sinclair, David A and Chen, Christopher S and Ozaki, C. Keith and Mitchell, James R
Cell (Cambridge), ISSN 0092-8674, 03/2018, Volume 173, Issue 1, pp. 117 - 129.e14
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3. Full Text Biological insights from 108 schizophrenia-associated genetic loci
by Ripke, Stephan and Neale, Benjamin M and Corvin, Aiden and Walters, James T. R and Farh, Kai-How and Holmans, Peter A and Lee, Phil and Bulik-Sullivan, Brendan and Collier, David A and Huang, Hailiang and Pers, Tune H and Agartz, Ingrid and Agerbo, Esben and Albus, Margot and Alexander, Madeline and Amin, Farooq and Bacanu, Silviu A and Begemann, Martin and Belliveau Jr, Richard A and Bene, Judit and Bergen, Sarah E and Bevilacqua, Elizabeth and Bigdeli, Tim B and Black, Donald W and Bruggeman, Richard and Buccola, Nancy G and Buckner, Randy L and Byerley, William and Cahn, Wiepke and Cai, Guiqing and Campion, Dominique and Cantor, Rita M and Carr, Vaughan J and Carrera, Noa and Catts, Stanley V and Chambert, Kimberly D and Chan, Raymond C. K and Chen, Ronald Y. L and Chen, Eric Y. H and Cheng, Wei and Cheung, Eric F. C and Chong, Siow Ann and Cloninger, C. Robert and Cohen, David and Cohen, Nadine and Cormican, Paul and Craddock, Nick and Crowley, James J and Curtis, David and Davidson, Michael and Davis, Kenneth L and Degenhardt, Franziska and Del Favero, Jurgen and Demontis, Ditte and Dikeos, Dimitris and Dinan, Timothy and Djurovic, Srdjan and Donohoe, Gary and Drapeau, Elodie and Duan, Jubao and Dudbridge, Frank and Durmishi, Naser and Eichhammer, Peter and Eriksson, Johan and Escott-Price, Valentina and Essioux, Laurent and Fanous, Ayman H and Farrell, Martilias S and Frank, Josef and Franke, Lude and Freedman, Robert and Freimer, Nelson B and Friedl, Marion and Friedman, Joseph I and Fromer, Menachem and Genovese, Giulio and Georgieva, Lyudmila and Giegling, Ina and Giusti-Rodríguez, Paola and Godard, Stephanie and Goldstein, Jacqueline I and Golimbet, Vera and Gopal, Srihari and Gratten, Jacob and De Haan, Lieuwe and Hammer, Christian and Hamshere, Marian L and Hansen, Mark and Hansen, Thomas and Haroutunian, Vahram and Hartmann, Annette M and Henskens, Frans A and Herms, Stefan and Hirschhorn, Joel N and Hoffmann, Per and Hofman, Andrea and Hollegaard, Mads V and Hougaard, David M and Ikeda, Masashi and Joa, Inge and ... and Psychiat Genomics Consortium and Wellcome Trust Case-Control Consor and Psychosis Endophenotypes Int Conso and Schizophrenia Working Group of the Psychiatric Genomics Consortium
Nature (London), ISSN 0028-0836, 2014, Volume 511, Issue 7510, pp. 421 - 427
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Schizophrenia | Genetic research | Research | Health aspects | Analysis | Studies | Confidence intervals | Hypotheses | Genealogy | Sample size | Genomics | Genetics | Trends | Index Medicus | Medicin och hälsovetenskap
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4. Full Text A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
by Fritsche, Lars and Igl, Wilmar and Cooke Bailey, Jessica N and Grassmann, Felix and Sengupta, Sebanti and Bragg-Gresham, Jennifer L and Burdon, K.P and Hebbring, Scott J and Wen, C and Gorski, Mathias and Kim, Ivana and Cho, D and Zack, D and Souied, Eric and Scholl, Henik and Bala, Elisa and ELee, K and Hunter, David and Sardell, R.J and Mitchell, Paul and Merriam, Joanna and Cipriani, Francesco and Hoffman, J.D and Schick, Tina and Lechanteur, Yara T. E and Guymer, Robyn and Johnson, Matthew and Jiang, Y and Stanton, Chloe and Buitendijk, Gabrielle and Zhan, Xiaowei and Kwong, A.M and Boleda, Alexis and Brooks, Matthew and Gieser, Linn and Ratna Priya, Rinki and Branham, Kari and Foerster, J.R and Heckenlively, John and Othman, Mohammad and Vote, Brendan J and Liang, H.H and Souzeau, Emmanuelle and McAllister, I.L and Isaacs, Timothy and Hall, J and Lake, S and Mackey, David and Constable, I.J and Craig, Jamie E and Kitchner, Terrie E and Yang, Z and Su, Z and Luo, H and Chen, D and Ouyang, H and Flagg, Ken and Lin, D and Mao, G and Ferreyra, Henry and Stark, Klaus and Strachwitz, Claudia and Wolf, A and Brandl, Caroline and Rudolph, G and Olden, Matthias and Morrison, Margaux and Morgan, Denise and Schu, Matthew and Ahn, J and Silvestri, Giuliana and Tsironi, Evangelia and Park, K.H and Farrer, Lindsay and Orlin, Anton and Brucker, A and Curcio, Christine A and Mohand-Sa'd, S and Sahel, José-Alain and Audo, Isabelle and Benchaboune, Mustapha and Cree, Angela and Rennie, C.A and Goverdhan, S.V and Grunin, Michelle and Hagbi-Levi, Shira and Campochiaro, Betsy and Katsanis, Nicholas and Holz, Frank and Blond, Frédéric and Blanché, H and Deleuze, J.-F and Igo, Robert and Truitt, Barbara and Peachey, Neal and Meuer, Stacy and Myers, Chelsea and Moore, E.L and Klein, Ronald and Hauser, Michael and ...
Nature genetics, ISSN 1061-4036, 02/2016, Volume 48, Issue 2, pp. 134 - 143
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Mutation | Macular Degeneration - genetics | Humans | Macular degeneration | Genetic variation | Development and progression | Genetic aspects | Gene expression | Identification and classification | Health aspects | Proteins | Studies | Confidence intervals | Datasets | Angiogenesis | Data analysis | Genealogy | Disease | Genomics | Quality control | Genomes | Index Medicus
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5. Full Text LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
by Bulik-Sullivan, Brendan K and Loh, Po-Ru and Finucane, Hilary K and Ripke, Stephan and Yang, Jian and Patterson, Nick and Daly, Mark J and Price, Alkes L and Neale, Benjamin M and Schizophrenia Working Grp and Schizophrenia Working Group of the Psychiatric Genomics Consortium
Nature genetics, ISSN 1061-4036, 2015, Volume 47, Issue 3, pp. 291 - +
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Regression Analysis | Sample Size | Computer Simulation | Humans | Polymorphism, Single Nucleotide | Genome, Human | Genome-Wide Association Study - methods | Linkage Disequilibrium | Usage | Genomes | Research | Regression analysis | Multifactorial traits | Studies | Heart attacks | Genealogy | Bias | Coronary vessels | Cardiovascular disease | Bone density | Software | Statistics | Methods | Index Medicus | Medicin och hälsovetenskap
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6. Full Text Mutations impairing GSK3-mediated MAF phosphorylation cause cataract, deafness, intellectual disability, seizures, and a down syndrome-like facies
by Niceta, Marcello and Stellacci, Emilia and Gripp, Karen W and Zampino, Giuseppe and Kousi, Maria and Anselmi, Massimiliano and Traversa, Alice and Ciolfi, Andrea and Stabley, Deborah and Bruselles, Alessandro and Caputo, Viviana and Cecchetti, Serena and Prudente, Sabrina and Fiorenza, Maria T and Boitani, Carla and Philip, Nicole and Niyazov, Dmitriy and Leoni, Chiara and Nakane, Takaya and Keppler-Noreuil, Kim and Braddock, Stephen R and Gillessen-Kaesbach, Gabriele and Palleschi, Antonio and Campeau, Philippe M and Lee, Brendan H.L and Pouponnot, Celio and Stella, Lorenzo and Bocchinfuso, Gianfranco and Katsanis, Nicholas and Sol-Church, Katia and Tartaglia, Marco
American journal of human genetics, ISSN 0002-9297, 05/2015, Volume 96, Issue 5, pp. 816 - 825
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Down Syndrome - pathology | Phosphorylation | Deafness - genetics | Seizures - genetics | Humans | Proto-Oncogene Proteins c-maf - genetics | Cataract - pathology | Intellectual Disability - pathology | Intellectual Disability - genetics | Phenotype | Seizures - pathology | Glycogen Synthase Kinase 3 - genetics | Down Syndrome - genetics | Cataract - genetics | Mutation | Deafness | Cataract | Gene mutations | Genetic aspects | Identification and classification | Mental retardation | Proteins | Genotype & phenotype | Amino acids | Index Medicus | Report
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7. Full Text Proteoglycan 4 expression protects against the development of osteoarthritis
by Ruan, Merry Z.C and Erez, Ayelet and Guse, Kilian and Dawson, Brian and Bertin, Terry and Chen, Yuqing and Jiang, Ming-Ming and Yustein, Jason and Gannon, Francis and Lee, Brendan H.L
Science translational medicine, ISSN 1946-6234, 03/2013, Volume 5, Issue 176, pp. 176ra34 - 176ra34
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Cell Line | Osteoarthritis - prevention & control | Humans | Laser Capture Microdissection | Osteoarthritis - metabolism | Proteoglycans - metabolism | Male | Mice, Transgenic | Promoter Regions, Genetic - genetics | Collagen Type II - genetics | Osteoarthritis - genetics | Animals | Mice | Proteoglycans - genetics | Index Medicus
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8.