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1. Full Text Randomized, Placebo-Controlled, Phase III Trial of Yeast-Derived Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Versus Peptide Vaccination Versus GM-CSF Plus Peptide Vaccination Versus Placebo in Patients With No Evidence of Disease After Complete Surgical Resection of Locally Advanced and/or Stage IV Melanoma: A Trial of the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group (E4697)
by Lawson, DH and Lee, S and Zhao, FM and Tarhini, AA and Margolin, KA and Ernstoff, MS and Atkins, MB and Cohen, GI and Whiteside, TL and Butterfield, LH and Kirkwood, JM
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 12/2015, Volume 33, Issue 34, pp. 4066 - 4066
Purpose We conducted a double-blind, placebo-controlled trial to evaluate the effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) and peptide... 
METASTATIC MELANOMA | DENDRITIC CELLS | ONCOLOGY | HIGH-DOSE INTERFERON-ALPHA-2B | ADJUVANT THERAPY | INTERGROUP | SARGRAMOSTIM | Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage | Prognosis | Double-Blind Method | Follow-Up Studies | HLA-A2 Antigen - immunology | Humans | Middle Aged | Vaccination | Male | Survival Rate | Vaccines, Subunit - immunology | Melanoma - pathology | Young Adult | Skin Neoplasms | Aged, 80 and over | Adult | Female | Aged | Peptide Fragments - therapeutic use | Melanoma - therapy | Neoplasm Staging | Cohort Studies | Melanoma - mortality | Mela5 | Original Reports
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2. Full Text Oncogenic Kras-Induced GM-CSF Production Promotes the Development of Pancreatic Neoplasia
by Pylayeva-Gupta, Yuliya and Lee, Kyoung Eun and Hajdu, Cristina H and Miller, George and Bar-Sagi, Dafna
Cancer Cell, ISSN 1535-6108, 06/2012, Volume 21, Issue 6, pp. 836 - 847
Stromal responses elicited by early stage neoplastic lesions can promote tumor growth. However, the molecular mechanisms that underlie the early recruitment of... 
COLONY-STIMULATING FACTORS | T-CELL RESPONSES | TUMOR PROGRESSION | P21 RAS | ONCOLOGY | DUCTAL ADENOCARCINOMA | INFLAMMATION | MOUSE | MICE | SUPPRESSOR-CELLS | CANCER | CELL BIOLOGY | Immunohistochemistry | Adenocarcinoma - pathology | Epithelial Cells - metabolism | Pancreatic Neoplasms - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Immunoblotting | Green Fluorescent Proteins - genetics | Pancreatic Ducts - metabolism | Carcinoma, Pancreatic Ductal - genetics | Adenocarcinoma - metabolism | RNA Interference | HEK293 Cells | CD8-Positive T-Lymphocytes - metabolism | Adenocarcinoma - genetics | Proto-Oncogene Proteins p21(ras) - metabolism | Green Fluorescent Proteins - metabolism | Pancreatic Ducts - cytology | Mice, Inbred C57BL | Pancreatic Neoplasms - pathology | Receptors, Chemokine - metabolism | Cells, Cultured | Mice, Transgenic | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Animals | Cell Transformation, Neoplastic | Myeloid Cells - metabolism | Mice | CD11b Antigen - metabolism | Microscopy, Fluorescence | T cells | Tumors | granulocyte-macrophage colony stimulating factor | immunosuppression | Kras | cancer | inflammation | pancreas
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3. Full Text IL-17A(+)GM-CSF+ Neutrophils Are the Major Infiltrating Cells in Interstitial Lung Disease in an Autoimmune Arthritis Model
by Kwon, OC and Lee, EJ and Chang, EJ and Youn, J and Ghang, B and Hong, S and Lee, CK and Yoo, B and Kim, YG
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 07/2018, Volume 9, p. 1544
Objective: To gain a better understanding of the pathogenesis of autoimmune arthritis-associated interstitial lung disease (ILD), we sought to identify the... 
RHEUMATOID-ARTHRITIS | IL-17A | COLONY-STIMULATING FACTOR | SKG MICE | IMMUNOLOGY | autoimmune arthritis | neutrophil | THYMIC STROMAL LYMPHOPOIETIN | BRONCHOALVEOLAR LAVAGE | SIGNAL-TRANSDUCTION | ZAP-70 | THERAPY | GM-CSF | interstitial lung disease | INFLAMMATION | Usage | Magnetic resonance imaging | Glucans | Lung diseases | Rheumatoid arthritis | Neutrophils | Diagnosis | Research
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4. Full Text GM-CSF Autoantibodies and Neutrophil Dysfunction in Pulmonary Alveolar Proteinosis
by Uchida, Kanji and Beck, David C and Yamamoto, Takashi and Berclaz, Pierre-Yves and Abe, Shuichi and Staudt, Margaret K and Carey, Brenna C and Filippi, Marie-Dominique and Wert, Susan E and Denson, Lee A and Puchalski, Jonathan T and Hauck, Diane M and Trapnell, Bruce C
The New England Journal of Medicine, ISSN 0028-4793, 02/2007, Volume 356, Issue 6, pp. 567 - 579
Infection, especially with opportunistic microbes, is a prominent feature of pulmonary alveolar proteinosis; extrapulmonary infection suggests a systemic... 
LUNG | MEDICINE, GENERAL & INTERNAL | PHAGOCYTOSIS | ACTIVATION | COLONY-STIMULATING FACTOR | BONE-MARROW | INNATE | MICE | MACROPHAGE DIFFERENTIATION | AUTOIMMUNE-DISEASE | PU.1 | Liver Diseases - immunology | Humans | Middle Aged | Neutrophils - physiology | Neutrophils - ultrastructure | Male | Granulocyte-Macrophage Colony-Stimulating Factor - physiology | Mice, Inbred Strains | Case-Control Studies | Cystic Fibrosis - immunology | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Autoantibodies - physiology | Pulmonary Alveolar Proteinosis - immunology | Adolescent | Adult | Female | Aged | Leukocyte Count | Mice | Child | Complications and side effects | Research | Pulmonary alveolar proteinosis | Granulocyte-macrophage colony stimulating factor | Health aspects | Flow cytometry | Infections | Lungs | Surfactants | Mortality | Apoptosis
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5. Full Text High‐gain mixer using cascode current bleeding and gm‐boosting techniques
by Lee, Ji‐Young and Yun, Tae‐Yeoul
Microwave and Optical Technology Letters, ISSN 0895-2477, 01/2017, Volume 59, Issue 1, pp. 1 - 6
ABSTRACT This paper presents a high‐gain down‐conversion mixer using a cascode current bleeding technique and a transconductance (gm)‐boosting technique.... 
current reuse | gm boosting | cascade | current bleeding
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6. Full Text Piglets produced from cloned blastocysts cultured in vitro with GM‐CSF
by Lee, Kiho and Redel, Bethany K and Spate, Lee and Teson, Jennifer and Brown, Alana N and Park, Kwang‐Wook and Walters, Eric and Samuel, Melissa and Murphy, Clifton N and Prather, Randall S
Molecular Reproduction and Development, ISSN 1040-452X, 02/2013, Volume 80, Issue 2, pp. 145 - 154
In general, pig embryos established by somatic cell nuclear transfer (SCNT) are transferred at the one‐cell stage because of suboptimal embryo culture... 
somatic cell nuclear transfer | GM‐CSF | embryo transfer | embryo culture | Embryo transfer | GM-CSF | Somatic cell nuclear transfer | Embryo culture | PIGS | SOMATIC-CELLS | APOPTOSIS | COLONY-STIMULATING FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL NUCLEAR TRANSFER | DEVELOPMENTAL BIOLOGY | CELL BIOLOGY | REPRODUCTIVE BIOLOGY | DISRUPTION | GENE | PORCINE EMBRYOS | MICE | BIRTH | Embryo Culture Techniques - veterinary | Cloning, Organism - methods | Nuclear Transfer Techniques - veterinary | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Reverse Transcriptase Polymerase Chain Reaction - veterinary | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Reproductive Techniques, Assisted - veterinary | Linear Models | DNA Primers - genetics | Real-Time Polymerase Chain Reaction - veterinary | Cloning, Organism - veterinary | Animals | Embryo Culture Techniques - methods | Sus scrofa - embryology | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Gene Expression Regulation, Developmental - physiology | Macrophage colony stimulating factor | Swine | Analysis | Cloning
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7. Full Text Heterogeneity of porcine bone marrow-derived dendritic cells induced by GM-CSF
by Kim, Sang Eun and Hwang, Jeong Ho and Kim, Young Kyu and Lee, Hoon Taek
PLoS ONE, ISSN 1932-6203, 11/2019, Volume 14, Issue 11, p. e0223590
In vitro generation of dendritic cells (DCs) is advantageous for overcoming the low frequency of primary DCs and the difficulty of applying isolation... 
Usage | Research | Dendritic cells | Gene expression | Granulocyte-macrophage colony stimulating factor | Cell culture | Flow cytometry | Biotechnology | Cytology | Infections | Lymphocytes T | Biology | Heterogeneity | Immunology | Swine | Lymphocytes | Bone marrow | Colony-stimulating factor | Immune system | Phenotypes | Granulocyte-macrophage colony-stimulating factor | Priming | Costimulator | Hogs | Morphology | Adenoviruses | Laboratory animals | Dendritic structure
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8. Full Text GM-CSF- and IRF4-Dependent Signaling Can Regulate Myeloid Cell Numbers and the Macrophage Phenotype during Inflammation
by Lee, MC and Lacey, DC and Fleetwood, AJ and Achuthan, A and Hamilton, JA and Cook, AD
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 05/2019, Volume 202, Issue 10, pp. 3033 - 3040
Studies have demonstrated the importance of a GM-CSF -> IFN regulatory factor 4 (IRF4)-> CCL17 pathway, first identified in monocytes/macrophages, for... 
RESPONSES | COLONY-STIMULATING FACTOR | DENDRITIC CELLS | IRF4 | IN-VIVO | DYNAMICS | RECEPTOR | CHEMOKINE | IMMUNOLOGY | CCL17 | MHC CLASS-II
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9. Full Text GM-CSF promotes macrophage alternative activation after renal ischemia/reperfusion injury
by Huen, Sarah C and Huynh, Larry and Marlier, Arnaud and Lee, Yashang and Moeckel, Gilbert W and Cantley, Lloyd G
Journal of the American Society of Nephrology, ISSN 1046-6673, 06/2015, Volume 26, Issue 6, pp. 1334 - 1345
After kidney ischemia/reperfusion (I/R) injury, nnonocytes home to the kidney and differentiate into activated macrophages. Whereas proinflammatory macrophages... 
ACUTE KIDNEY INJURY | CELLS | REPAIR | CONTRIBUTE | COLONY-STIMULATING FACTOR | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | HOUSE-DUST MITE | ISCHEMIA-REPERFUSION | POLARIZATION | STAT5 ACTIVATION | Immunohistochemistry | Multivariate Analysis | Up-Regulation | Cell Proliferation | Macrophage Activation - genetics | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Real-Time Polymerase Chain Reaction - methods | Male | Reperfusion Injury - metabolism | Disease Models, Animal | Kidney Tubules, Proximal - pathology | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Random Allocation | Acute Kidney Injury - physiopathology | Blotting, Western | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Phenotype | Animals | Analysis of Variance | Kidney Tubules, Proximal - metabolism | Reperfusion Injury - physiopathology | Mice | Acute Kidney Injury - metabolism | macrophages | cell signaling | renal proximal tubule cell | reperfusion | immunology | Basic Research | ischemic renal failure | ischemia
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10. Full Text Randomized, placebo-controlled, phase III trial of yeast- derIVed granulocyte-macrophage colony-stimulating factor (GM-CSF) versus peptide vaccination versus GM-CSF plus peptide vaccination versus placebo in patients with no evidence of disease after complete surgical resection of locally advanced and/or stage IV melanoma: A trial of the eastern cooperatIVe oncology groupâ€"American college of radiology imaging network cancer research group (E4697)
by Lawson, David H and Lee, Sandra and Zhao, Fengmin and Tarhini, Ahmad A and Margolin, Kim A and Ernstoff, Marc S and Atkins, Michael B and Cohen, Gary I and Whiteside, Theresa L and Butterfield, Lisa H and Kirkwood, John M
Journal of Clinical Oncology, ISSN 0732-183X, 12/2015, Volume 33, Issue 34, pp. 4066 - 4076
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11. Full Text THU0089 Il-17a+gm-csf+ neutrophils are the major infiltrating cells in interstitial lung disease in an autoimmune arthritis model
by Kwon, O.C and Lee, E.-J and Chang, E.-J and Seo, W.J and Oh, J.S and Hong, S and Lee, C.-K and Yoo, B and Kim, Y.-G
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2018, Volume 77, Issue Suppl 2, p. 267
BackgroundInterstitial lung disease (ILD) is a common extra-articular manifestation of rheumatoid arthritis (RA). Discrepancy in the effect of biologic agents... 
Flow cytometry | CD11b antigen | Cytokines | Granulocyte-macrophage colony-stimulating factor | Lung diseases | Neutrophils | Interleukin 22 | Interleukin 23 | Leukocytes (neutrophilic) | Inflammation | Injection | Tumor necrosis factor-α | Synovium | Interleukin 6 | Serum levels | Thymic stromal lymphopoietin | Magnetic resonance imaging | Lungs | Rheumatoid arthritis | γ-Interferon | Fibrosis
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12. Full Text Distinct role of FoxO1 in M‐CSF‐ and GM‐CSF‐differentiated macrophages contributes LPS‐mediated IL‐10: implication in hyperglycemia
by Chung, Sangwoon and Ranjan, Ravi and Lee, Yong Gyu and Park, Gye Young and Karpurapu, Manjula and Deng, Jing and Xiao, Lei and Kim, Ji Young and Unterman, Terry G and Christman, John W
Journal of Leukocyte Biology, ISSN 0741-5400, 02/2015, Volume 97, Issue 2, pp. 327 - 339
A novel role for FoxO1 in regulating macrophage phenotypic polarization and therapeutic interventions for chronic inflammatory conditions. Macrophages are a... 
monocyte | M1‐like | metabolic stress | M2‐like | inflammation | M2-like | Inflammation | M1-like | Monocyte | Metabolic stress | TRANSCRIPTION FACTORS | METABOLIC SYNDROME | COLONY-STIMULATING FACTOR | HIGH-FAT-DIET | INDUCED INFLAMMATION | IMMUNOLOGY | CELL BIOLOGY | INSULIN-RESISTANCE | HEMATOLOGY | NF-KAPPA-B | ALTERNATIVE ACTIVATION | LUNG INFLAMMATION | ADIPOSE-TISSUE | Forkhead Transcription Factors - immunology | Macrophage Activation - genetics | Humans | Male | Hyperglycemia - genetics | Cell Differentiation - genetics | Hyperglycemia - pathology | Macrophage Colony-Stimulating Factor - pharmacology | Female | Macrophages - immunology | Cell Line | Macrophages - pathology | Macrophage Activation - immunology | Hyperglycemia - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Forkhead Transcription Factors - genetics | Mice, Knockout | Cell Differentiation - immunology | Animals | Cell Differentiation - drug effects | Interleukin-10 - genetics | Lipopolysaccharides - pharmacology | Mice, Obese | Forkhead Box Protein O1 | Mice | Macrophage Activation - drug effects | Interleukin-10 - immunology | Inflammation, Extracellular Mediators, & Effector Molecules
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