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by Thompson, Eric M, MD and Hielscher, Thomas, MSc and Bouffet, Eric, Prof and Remke, Marc, MD and Luu, Betty, BSc and Gururangan, Sridharan, Prof and McLendon, Roger E, Prof and Bigner, Darell D, Prof and Lipp, Eric S, MD and Perreault, Sebastien, MD and Cho, Yoon-Jae, MD and Grant, Gerald, MD and Kim, Seung-Ki, Prof and Lee, Ji Yeoun, MD and Rao, Amulya A Nageswara, MD and Giannini, Caterina, Prof and Li, Kay Ka Wai, MD and Ng, Ho-Keung, Prof and Yao, Yu, MD and Kumabe, Toshihiro, MD and Tominaga, Teiji, Prof and Grajkowska, Wieslawa A, Prof and Perek-Polnik, Marta, Prof and Low, David C Y, MBBCh and Seow, Wan Tew, MBBS and Chang, Kenneth T E, MBBCh and Mora, Jaume, Prof and Pollack, Ian F, Prof and Hamilton, Ronald L, MD and Leary, Sarah, MD and Moore, Andrew S, PhD and Ingram, Wendy J, PhD and Hallahan, Andrew R, MBBS and Jouvet, Anne, MD and Fèvre-Montange, Michelle, PhD and Vasiljevic, Alexandre, MD and Faure-Conter, Cecile, MD and Shofuda, Tomoko, PhD and Kagawa, Naoki, MD and Hashimoto, Naoya, MD and Jabado, Nada, MD and Weil, Alexander G, MD and Gayden, Tenzin, PhD and Wataya, Takafumi, MD and Shalaby, Tarek, MD and Grotzer, Michael, Prof and Zitterbart, Karel, PhD and Sterba, Jaroslav, Prof and Kren, Leos, MD and Hortobágyi, Tibor, Prof and Klekner, Almos, PhD and László, Bognár, Prof and Pócza, Tímea, MSc and Hauser, Peter, MD and Schüller, Ulrich, MD and Jung, Shin, Prof and Jang, Woo-Youl, MD and French, Pim J, Prof and Kros, Johan M, Prof and van Veelen, Marie-Lise C, MD and Massimi, Luca, MD and Leonard, Jeffrey R, Prof and Rubin, Joshua B, MD and Vibhakar, Rajeev, MD and Chambless, Lola B, MD and Cooper, Michael K, MD and Thompson, Reid C, Prof and Faria, Claudia C, MD and Carvalho, Alice, MD and Nunes, Sofia, MD and Pimentel, José, MD and Fan, Xing, MD and Muraszko, Karin M, Prof and López-Aguilar, Enrique, MD and Lyden, David, Prof and Garzia, Livia, PhD and Shih, David J H, PhD and Kijima, Noriyuki, MD and Schneider, Christian, MD and Adamski, Jennifer, PhD and Northcott, Paul A, PhD and Kool, Marcel, PhD and Jones, David T W, PhD and Chan, Jennifer A, MD and Nikolic, Ana, MD and Garre, Maria Luisa, MD and Van Meir, Erwin G, Prof and Osuka, Satoru, MD and Olson, Jeffrey J, Prof and Jahangiri, Arman, BSc and Castro, Brandyn A, BSc and Gupta, Nalin, MD and Weiss, William A, Prof and Moxon-Emre, Iska, MSc and Mabbott, Donald J, PhD and Lassaletta, Alvaro, MD and Hawkins, Cynthia E, Prof and Tabori, Uri, MD and Drake, James, Prof and Kulkarni, Abhaya, Prof and ...
The Lancet Oncology, ISSN 1470-2045, 2016, Volume 17, Issue 4, pp. 484 - 495
Journal Article
by Morrissy, A. Sorana and Garzia, Livia and Shih, David J. H and Zuyderduyn, Scott and Huang, Xi and Skowron, Patryk and Remke, Marc and Cavalli, Florence M. G and Ramaswamy, Vijay and Lindsay, Patricia E and Jelveh, Salomeh and Donovan, Laura K and Wang, Xin and Luu, Betty and Zayne, Kory and Li, Yisu and Mayoh, Chelsea and Thiessen, Nina and Mercier, Eloi and Mungall, Karen L and Ma, Yusanne and Tse, Kane and Zeng, Thomas and Shumansky, Karey and Roth, Andrew J. L and Shah, Sohrab and Farooq, Hamza and Kijima, Noriyuki and Holgado, Borja L and Lee, John J. Y and Matan-Lithwick, Stuart and Liu, Jessica and Mack, Stephen C and Manno, Alex and Michealraj, K.A and Nor, Carolina and Peacock, John and Qin, Lei and Reimand, Juri and Rolider, Adi and Thompson, Yuan Y and Wu, Xiaochong and Pugh, Trevor and Ally, Adrian and Bilenky, Mikhail and Butterfield, Yaron S. N and Carlsen, Rebecca and Cheng, Young and Chuah, Eric and Corbett, Richard D and Dhalla, Noreen and He, An and Lee, Darlene and Li, Haiyan I and Long, William and Mayo, Michael and Plettner, Patrick and Qian, Jenny Q and Schein, Jacqueline E and Tam, Angela and Wong, Tina and Birol, Inanc and Zhao, Yongjun and Faria, Claudia C and Pimentel, José and Nunes, Sofia and Shalaby, Tarek and Grotzer, Michael and Pollack, Ian F and Hamilton, Ronald L and Li, Xiao-Nan and Bendel, Anne E and Fults, Daniel W and Walter, Andrew W and Kumabe, Toshihiro and Tominaga, Teiji and Collins, V. Peter and Cho, Yoon-Jae and Hoffman, Caitlin and Lyden, David and Wisoff, Jeffrey H and Garvin, James H and Stearns, Duncan S and Massimi, Luca and Schüller, Ulrich and Sterba, Jaroslav and Zitterbart, Karel and Puget, Stephanie and Ayrault, Olivier and Dunn, Sandra E and Tirapelli, Daniela P. C and Carlotti, Carlos G and Wheeler, Helen and Hallahan, Andrew R and Ingram, Wendy and MacDonald, Tobey J and Olson, Jeffrey J and Van Meir, Erwin G and Lee, Ji-Yeoun and Wang, Kyu-Chang and ...
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7586, pp. 351 - 357
The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related... 
HETEROGENEITY | CANCER EVOLUTION | CELLS | IMPACT | MULTIDISCIPLINARY SCIENCES | SUBGROUP MEDULLOBLASTOMA | DYNAMICS | MUTATIONS | SEQUENCING DATA | LYMPHOBLASTIC-LEUKEMIA | GENOME | Clone Cells - drug effects | Humans | Male | Medulloblastoma - therapy | Radiotherapy, Image-Guided | Selection, Genetic - drug effects | Drosophila melanogaster - genetics | Neoplasm Recurrence, Local - pathology | Medulloblastoma - radiotherapy | DNA Mutational Analysis | Medulloblastoma - pathology | Female | Medulloblastoma - surgery | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Molecular Targeted Therapy - methods | Disease Models, Animal | Signal Transduction | Neoplasm Recurrence, Local - therapy | Drosophila melanogaster - cytology | Cerebellar Neoplasms - genetics | Clone Cells - metabolism | Genome, Human - genetics | Xenograft Model Antitumor Assays | Animals | Clone Cells - pathology | Craniospinal Irradiation | Neoplasm Recurrence, Local - genetics | Mice | Cerebellar Neoplasms - therapy | Cerebellar Neoplasms - surgery | Cerebellar Neoplasms - radiotherapy | Clonal selection theory | Care and treatment | Medulloblastoma | Oncology, Experimental | Genetic aspects | Research | Cancer | Genes | Cloning | Clinical trials | Cytotoxicity | Genomes | Radiation therapy | Metastasis | Cancer therapies | Rodents | Medical prognosis | Mutation | Tumors | Index Medicus
Journal Article
by Shih, David J H and Shih, David J. H and Northcott, Paul A and Northcott, Paul A and Remke, Marc and Remke, Marc and Korshunov, Andrey and Korshunov, Andrey and Ramaswamy, Vijay and Ramaswamy, Vijay and Kool, Marcel and Kool, Marcel and Luu, Betty and Luu, Betty and Yao, Yuan and Yao, Yuan and Wang, Xin and Wang, Xin and Dubuc, Adrian M and Dubuc, Adrian M and Garzia, Livia and Garzia, Livia and Peacock, John and Peacock, John and Mack, Stephen C and Mack, Stephen C and Wu, Xiaochong and Wu, Xiaochong and Rolider, Adi and Rolider, Adi and Morrissy, A. Sorana and Morrissy, A Sorana and Cavalli, Florence M. G and Cavalli, Florence M G and Jones, David T. W and Jones, David T W and Zitterbart, Karel and Zitterbart, Karel and Faria, Claudia C and Faria, Claudia C and Schüller, Ulrich and Schüller, Ulrich and Kren, Leos and Kren, Leos and Kumabe, Toshihiro and Kumabe, Toshihiro and Tominaga, Teiji and Tominaga, Teiji and Ra, Young Shin and Shin Ra, Young and Garami, Miklós and Garami, Miklós and Hauser, Peter and Hauser, Peter and Chan, Jennifer A and Chan, Jennifer A and Robinson, Shenandoah and Robinson, Shenandoah and Bognár, László and Bognár, László and Klekner, Almos and Klekner, Almos and Saad, Ali G and Saad, Ali G and Liau, Linda M and Liau, Linda M and Albrecht, Steffen and Albrecht, Steffen and Fontebasso, Adam and Fontebasso, Adam and Cinalli, Giuseppe and Cinalli, Giuseppe and De Antonellis, Pasqualino and De Antonellis, Pasqualino and Zollo, Massimo and Zollo, Massimo and Cooper, Michael K and Cooper, Michael K and Thompson, Reid C and Thompson, Reid C and Bailey, Simon and Bailey, Simon and Lindsey, Janet C and Lindsey, Janet C and Di Rocco, Concezio and Di Rocco, Concezio and Massimi, Luca and Massimi, Luca and Michiels, Erna M. C and Michiels, Erna M C and Scherer, Stephen W and Scherer, Stephen W and Phillips, Joanna J and Phillips, Joanna J and Gupta, Nalin and Gupta, Nalin and Fan, Xing and Fan, Xing and Muraszko, Karin M and Muraszko, Karin M and ...
Journal of Clinical Oncology, ISSN 0732-183X, 2014, Volume 32, Issue 9, pp. 886 - 896
Journal Article
BMC CANCER, ISSN 1471-2407, 06/2019, Volume 19, Issue 1, pp. 571 - 15
BackgroundUsing a pathway-focused approach, we aimed to provide a subgroup-specific basis for finding novel therapeutic strategies and further refinement of... 
Prognosis | Targeted therapy | MOLECULAR SUBGROUPS | Subgroup | Metabolic pathway | FOXM1 | POLO-LIKE KINASE | CANCER | Signaling pathway | ONCOLOGY | Medulloblastoma | CHILDHOOD MEDULLOBLASTOMA | TARGETS | INHIBITOR | EXPRESSION | STRATIFICATION | PROGRAM | Platelet-derived growth factor | Fibroblast growth factors | Genetic aspects | Research | Tumor proteins | Pediatric research
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 11/2018, Volume 29, Issue 11, pp. 3614 - 3625
Journal Article
by Cavalli, Florence M.G and Remke, Marc and Rampasek, Ladislav and Peacock, John and Shih, David J.H and Luu, Betty and Garzia, Livia and Torchia, Jonathon and Nor, Carolina and Morrissy, A. Sorana and Agnihotri, Sameer and Thompson, Reid C and Thompson, Yuan Yao and Kuzan-Fischer, Claudia M and Farooq, Hamza and Isaev, Keren and Daniels, Craig and Cho, Byung-Kyu and Kim, Seung-Ki and Wang, Kyu-Chang and Lee, Ji Yeoun and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Vasiljevic, Alexandre and Faure-Conter, Cecile and Jouvet, Anne and Giannini, Caterina and Nageswara Rao, Amulya A and Li, Kay Ka Wai and Ng, Ho-Keung and Eberhart, Charles G and Pollack, Ian F and Hamilton, Ronald L and Gillespie, G. Yancey and Olson, James M and Leary, Sarah and Weiss, William A and Lach, Boleslaw and Chambless, Lola B and Cooper, Michael K and Vibhakar, Rajeev and Hauser, Peter and van Veelen, Marie-Lise C and Kros, Johan M and French, Pim J and Ra, Young Shin and Kumabe, Toshihiro and López-Aguilar, Enrique and Zitterbart, Karel and Sterba, Jaroslav and Finocchiaro, Gaetano and Massimino, Maura and Van Meir, Erwin G and Osuka, Satoru and Shofuda, Tomoko and Klekner, Almos and Zollo, Massimo and Leonard, Jeffrey R and Rubin, Joshua B and Jabado, Nada and Albrecht, Steffen and Mora, Jaume and Van Meter, Timothy E and Jung, Shin and Moore, Andrew S and Hallahan, Andrew R and Chan, Jennifer A and Tirapelli, Daniela P.C and Carlotti, Carlos G and Fouladi, Maryam and Pimentel, José and Faria, Claudia C and Saad, Ali G and Massimi, Luca and Liau, Linda M and Wheeler, Helen and Nakamura, Hideo and Elbabaa, Samer K and Perezpeña-Diazconti, Mario and Chico Ponce de León, Fernando and Robinson, Shenandoah and Zapotocky, Michal and Lassaletta, Alvaro and Huang, Annie and Hawkins, Cynthia E and Tabori, Uri and Bouffet, Eric and Bartels, Ute and Dirks, Peter B and Rutka, James T and Bader, Gary D and Reimand, Jüri and Goldenberg, Anna and Ramaswamy, Vijay and Taylor, Michael D
Cancer Cell, ISSN 1535-6108, 06/2017, Volume 31, Issue 6, pp. 737 - 754.e6
Journal Article
by Ramaswamy, Vijay and Hielscher, Thomas and Mack, Stephen C and Lassaletta, Alvaro and Lin, Tong and Pajtler, Kristian W and Jones, David T.W and Luu, Betty and Cavalli, Florence M.G and Aldape, Kenneth and Remke, Marc and Mynarek, Martin and Rutkowski, Stefan and Gururangan, Sridharan and McLendon, Roger E and Lipp, Eric S and Dunham, Christopher and Hukin, Juliette and Eisenstat, David D and Fulton, Dorcas and Van Landeghem, Frank K.H and Santi, Mariarita and Van Veelen, Marie-Lise C and Van Meir, Erwin G and Osuka, Satoru and Fan, Xing and Muraszko, Karin M and Tirapelli, Daniela P.C and Oba-Shinjo, Sueli M and Marie, Suely K.N and Carlotti, Carlos G and Lee, Ji Yeoun and Rao, Amulya A. Nageswara and Giannini, Caterina and Faria, Claudia C and Nunes, Sofia and Mora, Jaume and Hamilton, Ronald L and Hauser, Peter and Jabado, Nada and Petrecca, Kevin and Jung, Shin and Massimi, Luca and Zollo, Massimo and Cinalli, Giuseppe and Bognár, László and Klekner, Almos and Hortobágyi, Tibor and Leary, Sarah and Ermoian, Ralph P and Olson, James M and Leonard, Jeffrey R and Gardner, Corrine and Grajkowska, Wieslawa A and Chambless, Lola B and Cain, Jason and Eberhart, Charles G and Ahsan, Sama and Massimino, Maura and Giangaspero, Felice and Buttarelli, Francesca R and Packer, Roger J and Emery, Lyndsey and Yong, William H and Soto, Horacio and Liau, Linda M and Everson, Richard and Grossbach, Andrew and Shalaby, Tarek and Grotzer, Michael and Karajannis, Matthias A and Zagzag, David and Wheeler, Helen and Von Hoff, Katja and Alonso, Marta M and Tuñon, Teresa and Schüller, Ulrich and Zitterbart, Karel and Sterba, Jaroslav and Chan, Jennifer A and Guzman, Miguel and Elbabaa, Samer K and Colman, Howard and Dhall, Girish and Fisher, Paul G and Fouladi, Maryam and Gajjar, Amar and Goldman, Stewart and Hwang, Eugene and Kool, Marcel and Ladha, Harshad and Vera-Bolanos, Elizabeth and Wani, Khalida and Lieberman, Frank and Mikkelsen, Tom and Omuro, Antonio M and Pollack, Ian F and Prados, Michael and Robins, H. Ian and Soffietti, Riccardo and ...
Journal of Clinical Oncology, ISSN 0732-183X, 07/2016, Volume 34, Issue 21, pp. 2468 - 2477
Journal Article
Journal Article