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BBA - Molecular Cell Research, ISSN 0167-4889, 08/2019, Volume 1866, Issue 8, pp. 1282 - 1297
Fas-associated factor 1 (FAF1) was originally isolated as a Fas-associated factor and was subsequently found to interact with numerous other proteins that are... 
Ubiquitination | SUMO-interacting motifs | Mineralocorticoid receptor | Fas-associated factor 1
Journal Article
Biochimica et Biophysica Acta - Molecular Cell Research, ISSN 0167-4889, 2014, Volume 1843, Issue 9, pp. 2055 - 2066
Upregulation of Pin1 was shown to advance the functioning of several oncogenic pathways. It was recently shown that Pin1 is potentially an excellent prognostic... 
MiR-296-5p | Pin1 | Prostate cancer | TRANSFORMATION | CELLS | RNA | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPRESSION CONTRIBUTES | miR-296-5p | CELL BIOLOGY | OVEREXPRESSION | CARCINOGENESIS | GENE | DISEASE | PROLYL ISOMERASE PIN1 | MicroRNA | Analysis | Tumors
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2011, Volume 286, Issue 45, pp. 39247 - 39258
The antitumor activities of the novel adenosine monophosphate-activated protein kinase (AMPK) activator, OSU-53, were assessed in in vitro and in vivo models... 
METFORMIN | METASTASIS | MECHANISM | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | STAT3 | CADHERIN GENE-EXPRESSION | RISK | MESENCHYMAL TRANSITION | TRANSLATION | Enzyme Activators - pharmacology | Mitochondria - enzymology | AMP-Activated Protein Kinases - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Breast Neoplasms - enzymology | Mitochondria - genetics | Fatty Acids - genetics | Female | Energy Metabolism - genetics | Neoplasm Proteins - genetics | Thiazolidinediones - pharmacology | STAT3 Transcription Factor - genetics | Interleukin-6 - genetics | AMP-Activated Protein Kinases - antagonists & inhibitors | Protein Phosphatase 2 - genetics | Signal Transduction - genetics | Transcription Factors - genetics | Sulfonamides - pharmacology | Breast Neoplasms - drug therapy | STAT3 Transcription Factor - biosynthesis | Transcription Factors - metabolism | Animals | Breast Neoplasms - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Mice, Nude | Lipopolysaccharides - pharmacology | Protein Phosphatase 2 - metabolism | Cell Line, Tumor | Interleukin-6 - biosynthesis | Mice | AMP-Activated Protein Kinases - genetics | Energy Metabolism - drug effects | Fatty Acids - biosynthesis | Tumor Metabolism | Cancer Therapy | mTOR | Stat3 | AMP-activated Kinase (AMPK) | Metabolism | Akt PKB | Lipogenesis | Breast Cancer | Drug Discovery | IL-6
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 05/2019, Volume 20, Issue 9, p. 2199
Acrylamide (AA) and glycidamide (GA) can be produced in carbohydrate-rich food when heated at a high temperature, which can induce a malignant transformation.... 
prostate cancer | gene signature | cell cycle regulator | glycidamide | EMT | prognosis
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2019, Volume 512, Issue 3, pp. 629 - 634
During brain development, the expression of promyelocytic leukemia zinc finger (Plzf) in neural stem cells is precisely controlled to maintain the balance... 
E2f1 | Plzf | P19 cells | MAINTENANCE | BIOPHYSICS | P19 cells | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPRESSION | FAMILY | Medical colleges | Neurosciences | Diet therapy | Carcinoma | Neurons | Analysis | Leukemia | College graduates | Stem cells | DNA binding proteins | Genetic transcription | Cancer
Journal Article
Journal Article
Scientific reports, ISSN 2045-2322, 09/2018, Volume 8, Issue 1, pp. 13375 - 1
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. 
Glioblastoma multiforme | p53 Protein | Glioblastoma | Cell cycle
Journal Article
Experimental Biology and Medicine, ISSN 1535-3702, 3/2015, Volume 240, Issue 3, pp. 403 - 408
Journal Article
Scientific Reports, ISSN 2045-2322, 2014, Volume 4, Issue 1, p. 6394
Berberine (BBR), a traditional Chinese herbal medicine, was shown to display anticancer activity. In this study, we attempted to provide a global view of the... 
DRUG | BREAST-CANCER CELLS | APOPTOSIS | HEPATOCELLULAR-CARCINOMA | ACTIVATED PROTEIN-KINASE | NETWORK PHARMACOLOGY | MULTIDISCIPLINARY SCIENCES | AUTOPHAGY | HISTONE DEACETYLASE INHIBITORS | AMPK ACTIVATION | MAMMALIAN-CELLS | AMP-Activated Protein Kinases - metabolism | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Humans | Tubulin - genetics | Gene Expression Profiling | Breast Neoplasms - metabolism | Tubulin - metabolism | Flow Cytometry | Biomarkers, Tumor - metabolism | Female | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Drugs, Chinese Herbal | Histone Deacetylases - genetics | RNA, Messenger - genetics | Histone Deacetylases - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Breast Neoplasms - drug therapy | Blotting, Western | Berberine - pharmacology | Cell Movement - drug effects | Breast Neoplasms - genetics | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Cell Cycle - drug effects | AMP-Activated Protein Kinases - genetics | TOR protein | Cell proliferation | Biotechnology | Berberine | Histone deacetylase | AMP | Protein biosynthesis | AKT protein | Rapamycin | Kinases | Gene expression | AMP-activated protein kinase | Proteins | Herbal medicine | Databases | Tubulin | Protein synthesis | Cell cycle | Antitumor activity | Acetylation | Protein interaction | Endoplasmic reticulum | Phagocytosis | Cancer
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1661-6596, 08/2019, Volume 20, Issue 16, p. 3849
Colorectal cancer (CRC) is a heterogeneous disease resulting from the combined influence of many genetic factors. This complexity has caused the molecular... 
BIOMARKERS | colorectal cancer | gene signature | BIOCHEMISTRY & MOLECULAR BIOLOGY | metallothionein | prognosis | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Genes, ISSN 2073-4425, 09/2019, Volume 10, Issue 10, p. 766
Pancreatic ductal adenocarcinoma (PDAC) is the most common and aggressive type of pancreatic cancer. The five-year survival rate of PDAC is very low (less than... 
SMAD4 | in silico | cell cycle | bioinformatics | pancreatic ductal adenocarcinoma
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0181034
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 11006 - 16
Concomitant expressions of glycan-binding proteins and their bound glycans regulate many pathophysiologic processes, but this issue has not been addressed in... 
CANCER-CELLS | MIGRATION | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | COMPLEXES | PROLIFERATION | DEATH | MICE | RECEPTORS | EXPRESSION | BINDING | Oral carcinoma | Stellate cells | Platelet-derived growth factor | Wound healing | Transforming growth factor | Liver | Methionine | Neuropilin | Homeostasis | Galectin-1 | Glycosylation | N-glycans | Gene expression | Cell surface | Polysaccharides | Collagen | Rodents | Choline | Fibrosis | Growth factors
Journal Article