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by Howson, Joanna M M and Zhao, Wei and Barnes, Daniel R and Ho, Weang-Kee and Young, Robin and Paul, Dirk S and Waite, Lindsay L and Freitag, Daniel F and Fauman, Eric B and Salfati, Elias L and Sun, Benjamin B and Eicher, John D and Johnson, Andrew D and Sheu, Wayne H H and Nielsen, Sune F and Lin, Wei-Yu and Surendran, Praveen and Malarstig, Anders and Wilk, Jemma B and Tybjærg-Hansen, Anne and Rasmussen, Katrine L and Kamstrup, Pia R and Deloukas, Panos and Erdmann, Jeanette and Kathiresan, Sekar and Samani, Nilesh J and Schunkert, Heribert and Watkins, Hugh and Do, Ron and Rader, Daniel J and Johnson, Julie A and Hazen, Stanley L and Quyyumi, Arshed A and Spertus, John A and Pepine, Carl J and Franceschini, Nora and Justice, Anne and Reiner, Alex P and Buyske, Steven and Hindorff, Lucia A and Carty, Cara L and North, Kari E and Kooperberg, Charles and Boerwinkle, Eric and Young, Kristin and Graff, Mariaelisa and Peters, Ulrike and Absher, Devin and Hsiung, Chao A and Lee, Wen-Jane and Taylor, Kent D and Chen, Ying-Hsiang and Lee, I-Te and Guo, Xiuqing and Chung, Ren-Hua and Hung, Yi-Jen and Rotter, Jerome I and Juang, Jyh-Ming J and Quertermous, Thomas and Wang, Tzung-Dau and Rasheed, Asif and Frossard, Philippe and Alam, Dewan S and Majumder, Abdulla al Shafi and Di Angelantonio, Emanuele and Chowdhury, Rajiv and Chen, Yii-Der Ida and Nordestgaard, Børge G and Assimes, Themistocles L and Danesh, John and Butterworth, Adam S and Saleheen, Danish and EPIC-CVD and CARDIoGRAMplusC4D
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 7, pp. 1113 - 1119
Journal Article
PloS one, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0154672
...Author(s): Wei-Ming Chen [sup.1] [sup.2] [sup.3], Wayne H-H Sheu [sup.4] [sup.5] [sup.6] [sup.7], Pei-Chi Tseng [sup.1], Tzong-Shyuan Lee [sup.8], Wen-Jane Lee... 
ABCA1 | HDL | DENSITY-LIPOPROTEIN CHOLESTEROL | METAANALYSIS | PITAVASTATIN | PATHWAY | MULTIDISCIPLINARY SCIENCES | RISK | FLUVASTATIN | PRAVASTATIN | ATORVASTATIN | Gene Expression Regulation - genetics | Humans | Middle Aged | Male | Metabolic Syndrome - metabolism | Glucose - pharmacology | Cholesterol - metabolism | Down-Regulation - drug effects | Down-Regulation - genetics | Gene Expression Regulation - drug effects | Macrophages - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Metabolic Syndrome - genetics | Female | Macrophages - drug effects | RAW 264.7 Cells | Biological Transport - drug effects | Mice | MicroRNAs - genetics | Homeostasis - drug effects | ATP Binding Cassette Transporter 1 - genetics | Complications and side effects | MicroRNA | Physiological aspects | Development and progression | Dosage and administration | Genetic aspects | Research | Metabolic syndrome X | Macrophages | Statins | Drugs | Lipoproteins (low density) | Post-transcription | Regulations | Systemic diseases | Gene regulation | Homeostasis | Cardiovascular disease | Biochemistry | Glucose | Metabolic syndrome | ABCA1 protein | Proteins | Hyperglycemia | Modulation | Hepatology | Gastroenterology | Atherosclerosis | Bone marrow | Hemoglobin | miRNA | ABC transporters | Lipoproteins (high density) | Efflux | Internal medicine | Abnormalities | Federal regulation | Gene expression | Ribonucleic acid--RNA | Cholesterol | Medicine | Hospitals | 3' Untranslated regions | MicroRNAs | Atorvastatin | ATP-binding protein | Diabetes | Molecular biology | ATP | Transporter | Metabolic disorders | Endocrinology | RNA | Ribonucleic acid
Journal Article
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 5485 - 9
... reduction in pulse pressure after a one-hour rest in nurses working night shifts I-Te Lee1,2,3, Wayne Huey-Herng Sheu1,2,3, Wen-Jane Lee4 & Der-Yuan Chen2,5,6 Night... 
RECOVERY | DEPRESSION | COFFEE | MULTIDISCIPLINARY SCIENCES | DISEASE | CARDIOVASCULAR MORTALITY | CAFFEINE | RISK | HYPERTENSION | STRESS | BLOOD-PRESSURE | Blood pressure | Brain-derived neurotrophic factor | Nighttime | Nurses | Central nervous system | Shift work
Journal Article
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 3, p. e0138014
Journal Article
Journal of vascular surgery, ISSN 0741-5214, 2010, Volume 52, Issue 5, pp. 1290 - 1300
Background LOX-1, a lectin-like receptor on endothelial cells, facilitates the uptake of oxidized low-density lipoprotein (oxLDL). Expression of LOX-1 is... 
Surgery | SURGERY | APOPTOSIS | NAD(P)H OXIDASE | ACTIVATION | THERAPY | LOW-DENSITY-LIPOPROTEIN | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | PROLIFERATION | NF-KAPPA-B | RECEPTOR-1 | BIOAVAILABILITY | Phosphorylation | Reactive Oxygen Species - metabolism | Humans | NADPH Oxidases - metabolism | NF-kappa B - metabolism | Dose-Response Relationship, Drug | Inflammation - metabolism | Inflammation Mediators - metabolism | Superoxides - metabolism | Lipoproteins, LDL - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-8 - metabolism | Nitric Oxide Synthase Type III - metabolism | Interleukin-6 - metabolism | Ellagic Acid - pharmacology | Anti-Inflammatory Agents - pharmacology | Endothelial Cells - metabolism | Down-Regulation | NADPH Oxidases - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Inflammation - immunology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Cell Adhesion Molecules - metabolism | Endothelial Cells - immunology | Scavenger Receptors, Class E - metabolism | Signal Transduction - drug effects | Inflammation - prevention & control | Nitric Oxide - metabolism | Endothelial Cells - drug effects | Nitric Oxide Synthase Type II - metabolism | Antioxidants | Medical colleges | Ellagic acid | Low density lipoproteins | Nitric oxide | Atherosclerosis | Therapeutics, Physiological | Physical therapy | Endothelium
Journal Article
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 7378 - 9
... on endothelin-1 in patients with coronary artery disease ‒ a cross-sectional study Yu-Hsuan Li1, Wayne Huey-Herng Sheu1,2, Wen-Jane Lee3, Jun -Sing Wang1,2, Chia-Po Fu1, Kae... 
C-REACTIVE PROTEIN | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | CARDIOVASCULAR-DISEASE | ANGIOTENSIN-ALDOSTERONE SYSTEM | RISK | TRANSPLANT RECIPIENTS | PLASMA ENDOTHELIN-1 | DYSFUNCTION | HYPERTENSION | BLOOD-PRESSURE | Kidneys | Diabetes mellitus | Coronary vessels | Coronary artery | Vasoconstriction | Cardiovascular disease | Catecholamines | Blood pressure | Endothelin 1 | Kidney diseases | Cardiovascular diseases | Heart diseases
Journal Article
by Wu, Ying and Waite, Lindsay L and Jackson, Anne U and Sheu, Wayne H-H and Buyske, Steven and Absher, Devin and Arnett, Donna K and Boerwinkle, Eric and Bonnycastle, Lori L and Carty, Cara L and Cheng, Iona and Cochran, Barbara and Croteau-Chonka, Damien C and Dumitrescu, Logan and Eaton, Charles B and Franceschini, Nora and Guo, Xiuqing and Henderson, Brian E and Hindorff, Lucia A and Kim, Eric and Kinnunen, Leena and Komulainen, Pirjo and Lee, Wen-Jane and Le Marchand, Loic and Lin, Yi and Lindström, Jaana and Lingaas-Holmen, Oddgeir and Mitchell, Sabrina L and Narisu, Narisu and Robinson, Jennifer G and Schumacher, Fred and Stančáková, Alena and Sundvall, Jouko and Sung, Yun-Ju and Swift, Amy J and Wang, Wen-Chang and Wilkens, Lynne and Wilsgaard, Tom and Young, Alicia M and Adair, Linda S and Ballantyne, Christie M and Bůžková, Petra and Chakravarti, Aravinda and Collins, Francis S and Duggan, David and Feranil, Alan B and Ho, Low-Tone and Hung, Yi-Jen and Hunt, Steven C and Hveem, Kristian and Juang, Jyh-Ming J and Kesäniemi, Antero Y and Kuusisto, Johanna and Laakso, Markku and Lakka, Timo A and Lee, I-Te and Leppert, Mark F and Matise, Tara C and Moilanen, Leena and Njølstad, Inger and Peters, Ulrike and Quertermous, Thomas and Rauramaa, Rainer and Rotter, Jerome I and Saramies, Jouko and Tuomilehto, Jaakko and Uusitupa, Matti and Wang, Tzung-Dau and Boehnke, Michael and Haiman, Christopher A and Chen, Yii-Der I and Kooperberg, Charles and Assimes, Themistocles L and Crawford, Dana C and Hsiung, Chao A and North, Kari E and Mohlke, Karen L
PLoS genetics, ISSN 1553-7404, 2013, Volume 9, Issue 3, p. e1003379
Genome-wide association studies (GWAS) have identified similar to 100 loci associated with blood lipid levels, but much of the trait heritability remains... 
COMMON VARIANTS | DENSITY-LIPOPROTEIN CHOLESTEROL | FUNCTIONAL POLYMORPHISM | GENE | GENOTYPE IMPUTATION | GENETICS & HEREDITY | RISK | LIPASE | COMPLEX TRAITS | CORONARY-ARTERY-DISEASE | GENOME-WIDE ASSOCIATION | Apolipoprotein A-V | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Apolipoproteins A - genetics | Lipoproteins, HDL - genetics | Lipoproteins, HDL - blood | Humans | African Americans - genetics | Cholesterol, HDL - genetics | Lipoproteins, LDL - genetics | Proprotein Convertases - genetics | Cholesterol, LDL - genetics | Serine Endopeptidases - genetics | Triglycerides - blood | Cholesterol, HDL - blood | Cholesterol, LDL - blood | Triglycerides - genetics | Lipoproteins, LDL - blood | Proprotein Convertase 9 | Quantitative genetics | Genetic variation | Physiological aspects | Cholesterol, LDL | Genetic aspects | Research | Population genetics | Health aspects | Medisinsk genetikk: 714 | VDP | Basic medical, dental and veterinary science disciplines: 710 | Medical molecular biology: 711 | Medical genetics: 714 | Medisinske Fag: 700 | Medisinsk molekylærbiologi: 711 | Medical disciplines: 700 | Basale medisinske, odontologiske og veterinærmedisinske fag: 710 | Medical research | Genealogy | Womens health | African Americans | Population | Genomes | Gene loci | Gene expression | Epidemiology | Cholesterol
Journal Article
by Wen, Wanqing and Zheng, Wei and Okada, Yukinori and Takeuchi, Fumihiko and Tabara, Yasuharu and Hwang, Joo-Yeon and Dorajoo, Rajkumar and Li, Huaixing and Tsai, Fuu-Jen and Yang, Xiaobo and He, Jiang and Wu, Ying and He, Meian and Zhang, Yi and Liang, Jun and Guo, Xiuqing and Sheu, Wayne H.uey-Herng and Delahanty, Ryan and Guo, Xingyi and Kubo, Michiaki and Yamamoto, Ken and Ohkubo, Takayoshi and Go, Min J.in and Liu, Jian J.un and Gan, Wei and Chen, Ching-Chu and Gao, Yong and Li, Shengxu and Lee, Nanette R and Wu, Chen and Zhou, Xueya and Song, Huaidong and Yao, Jie and Lee, I-Te and Long, Jirong and Tsunoda, Tatsuhiko and Akiyama, Koichi and Takashima, Naoyuki and Cho, Yoon S.hin and Ong, Rick T.h and Lu, Ling and Chen, Chien-Hsiun and Tan, Aihua and Rice, Treva K and Adair, Linda S and Gui, Lixuan and Allison, Matthew and Lee, Wen-Jane and Cai, Qiuyin and Isomura, Minoru and Umemura, Satoshi and Kim, Young J.in and Seielstad, Mark and Hixson, James and Xiang, Yong-Bing and Isono, Masato and Kim, Bong-Jo and Sim, Xueling and Lu, Wei and Nabika, Toru and Lee, Juyoung and Lim, Wei-Yen and Gao, Yu-Tang and Takayanagi, Ryoichi and Kang, Dae-Hee and Wong, Tien Y.in and Hsiung, Chao A.gnes and Wu, I-Chien and Juang, Jyh-Ming J.immy and Shi, Jiajun and Choi, Bo Y.oul and Aung, Tin and Hu, Frank and Kim, Mi K.yung and Lim, Wei Y.en and Wang, Tzung-Dao and Shin, Min-Ho and Lee, Jeannette and Ji, Bu-Tian and Lee, Young-Hoon and Young, Terri L and Shin, Dong H.oon and Chun, Byung-Yeol and Cho, Myeong-Chan and Han, Bok-Ghee and Hwu, Chii-Min and Assimes, Themistocles L and Absher, Devin and Yan, Xiaofei and Kim, Eric and Kuo, Jane Z and Kwon, Soonil and Taylor, Kent D and Chen, Yii-Der I and Rotter, Jerome I and Qi, Lu and Zhu, Dingliang and Wu, Tangchun and Mohlke, Karen L and Gu, Dongfeng and ...
Human molecular genetics, ISSN 0964-6906, 10/2014, Volume 23, Issue 20, pp. 5492 - 5504
Journal Article