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Nature Genetics, ISSN 1061-4036, 12/2017, Volume 49, Issue 12, pp. 1779 - 1784
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 1/2016, Volume 53, Issue 1, pp. 95 - 108
Journal Article
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 06/2019, Volume 10, Issue 1, pp. 2400 - 16
Journal Article
Cell Reports, ISSN 2211-1247, 10/2019, Volume 29, Issue 1, pp. 118 - 134.e8
The mitogen-activated protein kinase (MAPK) pathway is a critical effector of oncogenic RAS signaling, and MAPK pathway inhibition may be an effective... 
synthetic lethal | KRAS | MEK inhibitor | SHOC2 | Ras | CRISPR-Cas9 screen | DRUG | FEEDBACK ACTIVATION | MELANOMA | STRATEGY | ACQUIRED-RESISTANCE | KRAS-MUTANT LUNG | BRAF | MAPK PATHWAY | PROMOTES | REVEALS | CELL BIOLOGY
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 2019, Volume 79, Issue 9, pp. 2352 - 2366
Combinatorial inhibition of MEK1/2 and CDK4/6 is currently undergoing clinical investigation in NRAS-mutant melanoma. To prospectively map the landscape of... 
DEPENDENCY | ONCOLOGY | SENSITIVITY | KRAS | SCALE | COMBINATION | CANCER
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2016, Volume 24, pp. S292 - S293
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2018, Volume 128, Issue 1, pp. 446 - 462
Journal Article
Neurobiology of aging, ISSN 0197-4580, 7/2014, Volume 35, Issue 7, pp. 1712 - 1721
Dopamine (DA) neurons in sporadic Parkinson disease (PD) display dysregulated gene expression networks and signaling pathways that are implicated in PD... 
miR-126 | dopamine neurons | miRNAs | insulin | PI3K | postmortem | IGF-1 signaling | Parkinson disease | cell systems | laser capture microdissection | 6-OHDA neurotoxicity
Journal Article
MOLECULAR CANCER RESEARCH, ISSN 1541-7786, 11/2019, Volume 17, Issue 11, pp. 2281 - 2293
High-grade serous ovarian cancer (HGSOC) is often sensitive to initial treatment with platinum and taxane combination chemotherapy, but most patients relapse... 
BCL-X-L | CELLS | INHIBITION | PREDICTOR | ONCOLOGY | PROGNOSIS | MCL-1 EXPRESSION | SENSITIVITY | CHEMORESISTANCE | CARCINOMA | BCL-X(L) | CELL BIOLOGY
Journal Article