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Nature Medicine, ISSN 1078-8956, 05/2017, Volume 23, Issue 5, pp. 579 - 589
Journal Article
Gut, ISSN 0017-5749, 01/2013, Volume 62, Issue 1, pp. 83 - 93
Objective Wnt signalling is critical for normal intestinal development and homeostasis. Wnt dysregulation occurs in almost all human and murine intestinal... 
LOCATION | SUPPRESSOR | COLORECTAL TUMORS | MUTATION CLUSTER REGION | APC GENE | FAMILIAL ADENOMATOUS POLYPOSIS | COLON | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | CANCER | SOMATIC MUTATIONS | Intestinal Mucosa - metabolism | Cell Count | Humans | Homeostasis | Wnt Signaling Pathway - physiology | Intestines - metabolism | Wnt Proteins - metabolism | Genes, APC | Intestinal Mucosa - cytology | In Situ Hybridization | Wnt Proteins - genetics | Biomarkers, Tumor - metabolism | Intestinal Neoplasms - genetics | Intestines - pathology | Intestinal Neoplasms - metabolism | Mice, Transgenic | Genetic Markers | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | Intestinal Neoplasms - pathology | Animals | Stem Cells - physiology | Biomarkers, Tumor - genetics | Mice | Mutation | Intestinal Mucosa - pathology | Intestines - cytology | Physiological aspects | Development and progression | Genetic aspects | Research | Wnt proteins | Gastrointestinal tumors | Medical research | Transcription factors | Genes | Rodents | Colorectal cancer | Epigenetics | Ligands | Physiology | Kinases | Tumors | IBD basic research | colonic neoplasms | microsatellite instability | colorectal adenomas | Wnt signalling | colonic adenomas | 5-aminosalicylic acid (5-ASA) | gastrointestinal immune response | infliximab | histopathology | IBD | just-right hypothesis | colonic polyps | mucosal defense | necrotising enterocolitis | adenoma | cancer genetics | carcinogenesis | colorectal function | inflammation | celiac disease | cancer syndromes | clinical trials | Barretts carcinoma | colorectal cancer genes | mucosal immunity | stem cells | colorectal cancer | colorectal diseases | colorectal neogenesis | epithelial cells | Crohn's disease | colorectal carcinoma | paneth cells | Barrett's oesophagus | colon carcinogenesis | mathematical modelling | epithelial barrier | gastrointestinal cancer | cancer | 1506 | Original
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2015, Volume 21, Issue 1, pp. 62 - 70
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2015, Volume 373, Issue 16, pp. 1578 - 1579
To the Editor: Luzzatto and Pandolfi (July 2 issue) 1 highlight the combined role of stem-cell turnover, stochastic mutation, and environmental mutagens in the... 
MEDICINE, GENERAL & INTERNAL | INFLAMMATORY-BOWEL-DISEASE | Neoplasms - etiology | Cell Transformation, Neoplastic - genetics | Humans | Carcinogenesis - genetics | Adenocarcinoma | Inflammatory bowel diseases | Mutagens | Intestine | Stem cells | Crohn's disease | Inflammation | Stochasticity | Cancer | Crohns disease | Colon | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of Pathology, ISSN 0022-3417, 11/2014, Volume 234, Issue 3, pp. 292 - 295
The last decade has seen huge improvements in our understanding of intestinal stem cell biology, with major advances arising from the ability to transgenically... 
intestine | stem cell | FAP | mtDNA | Invited | cytochome c oxidase | crypt map
Journal Article
The Journal of Pathology, ISSN 0022-3417, 11/2014, Volume 234, Issue 3, pp. 292 - 295
The last decade has seen huge improvements in our understanding of intestinal stem cell biology, with major advances arising from the ability to transgenically... 
cytochome c oxidase | crypt map | intestine | stem cell | FAP | mtDNA | MITOCHONDRIAL-DNA MUTATIONS | TUMOR | PATHOLOGY | CANCER | ORIGIN | PROGENITOR | EVOLUTION | ONCOLOGY | IN-VIVO | EXPANSION | CRYPT | LGR5 | Colon - cytology | Stem Cells - cytology | Animals | Cell Differentiation - physiology | Humans | Measurement | Gene mutations | Analysis | Stem cells | Cytochrome oxidase | Genetic engineering | Mitochondrial DNA | Genetic polymorphisms
Journal Article
The Journal of Pathology, ISSN 0022-3417, 11/2014, Volume 234, Issue 3, pp. 292 - 295
Journal Article
The Journal of Pathology, ISSN 0022-3417, 08/2016, Volume 239, Issue 4, pp. 387 - 390
Journal Article
The Journal of Pathology, ISSN 0022-3417, 08/2016, Volume 239, Issue 4, pp. 387 - 390
The adenoma–carcinoma sequence describes the development of colorectal carcinoma (CRC) from benign colorectal precursor lesions. Molecular classification of... 
traditional serrated adenoma | colorectal polyps | Wnt signalling | CELLS | APC | ONCOLOGY | NEOPLASIA | GROWTH | COLON | PATHOLOGY | CANCER | Intestinal Polyps | United Kingdom | Colonic Polyps - genetics | Adenoma - genetics | Colorectal Neoplasms - genetics | Humans | Development and progression | Polyps (Pathology) | Adenoma | Colorectal cancer | Index Medicus
Journal Article
Virchows Archiv, ISSN 0945-6317, 1/2018, Volume 472, Issue 1, pp. 43 - 54
Barrett’s oesophagus surveillance biopsies represent a significant share of the daily workload for a busy histopathology department. Given the emphasis on... 
Pathology | Metaplasia | Inflammation | Medicine & Public Health | Lineage tracing | Barrett’s oesophagus | Adenocarcinoma | Dysplasia | Histopathology | Endoscopes | Wound healing | Surveillance | Intestine | Patients | Esophagus | Cancer | Invited Annual Review Issue
Journal Article
Journal Article
Cell Stem Cell, ISSN 1934-5909, 02/2017, Volume 20, Issue 2, pp. 153 - 154
The existence and interaction of proliferating and quiescent intestinal stem cells have been debated since their discovery in the 1970s. In this issue of ,... 
SMALL-INTESTINE | MARKER | LGR5 | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Animals | Organoids - cytology | Cell Differentiation | Mice | Stem Cells - cytology | Enteroendocrine Cells - cytology | Intestines - cytology
Journal Article
Gut, ISSN 0017-5749, 04/2019, Volume 68, Issue 4, pp. 684 - 692
Journal Article