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1. Full Text French Intensive Care Society, International congress – Réanimation 2016
by Jaillette, Emmanuelle and Girault, Christophe and Brunin, Guillaume and Zerimech, Farid and Chiche, Arnaud and Broucqsault-Dedrie, Céline and Fayolle, Cyril and Minacori, Franck and Alves, Isabelle and Barrailler, Stephanie and Robriquet, Laurent and Delaporte, Emmanuel and Thellier, Damien and Delcourte, Claire and Duhamel, Alain and Nseir, Saad and Valette, Xavier and Desmeulles, Isabelle and Savary, Benoit and Masson, Romain and Seguin, Amélie and Daubin, Cédric and Sauneuf, Bertrand and Verrier, Pierre and Pottier, Véronique and Orabona, Marie and Samba, Désiré and Viquesnel, Gérald and Lermuzeaux, Mathilde and Hazera, Pascal and Hanouz, Jean-Luc and Parienti, Jean-Jacques and Du Cheyron, Damien and Demoule, Alexandre and Clavel, Marc and Rolland-Debord, Camille and Perbet, Sébastien and Terzi, Nicolas and Kouatchet, Achille and Wallet, Florent and Roze, Hadrien and Vargas, Frédéric and Guérin, Claude and Dellamonica, Jean and Jaber, Samir and Similowski, Thomas and Quenot, Jean-Pierre and Binquet, Christine and Vinsonneau, Christophe and Barbar, Saber-Davide and Vinault, Sandrine and Deckert, Valérie and Lemaire, Stephanie and Hssain, Ali Ait and Bruyère, Rémi and Souweine, Bertrand and Lagrost, Laurent and Adrie, Christophe and Jung, Boris and Daurat, Aurelien and De Jong, Audrey and Chanques, Gérald and Mahul, Martin and Monnin, Marion and Molinari, Nicolas and Lheureux, Olivier and Trepo, Eric and Hites, Maya and Cotton, Frederic and Wolff, Fleur and Surin, Rudy and Créteur, Jacques and Vincent, Jean-Louis and Gustot, Thierry and Jacobs, Frederique and Taccone, Fabio Silvio and Neuville, Mathilde and Timsit, Jean-François and El-Helali, Najoua and Le Monnier, Alban and Magalhaes, Eric and Radjou, Aguila and Smonig, Roland and Soubirou, Jean-François and Voiriot, Guillaume and Sonneville, Romain and Bouadma, Lila and Mourvillier, Bruno and Gélisse, Elodie and Brasseur, Alexandre and Roisin, Sandrine and De Backer, Daniel and Van Ruychevelt, Valerie and Carlier, Eric and Piagnerelli, Michael and Vanhaeverbeek, Michel and Danguy, Christine and Biston, Patrick and Au, Siu-Ming and Begot, Emmanuelle and ... and Qualité et Sécurité des Soins - CBPR-CFAR and Brain Liver Pitié-Salpêtrière Study Group (BLIPS), Paris, France and Working Group on Mechanical Ventilation and Outcomerea Study Group and COCOONs Study Group and Groupe ALIVE and For the GrrrOH: Groupe de recherche en réanimation respiratoire en Onco-Hématologie (Group for Research in Respiratory Intensive Care Onco-Hematology and EPURE Study Group and For the OUTCOMEREA Study Group and For the BIBLIOFLASH Study Group and Groupe de Recherche en Réanimation Respiratoire et Onco-Hematologique (GRRROH) and RETROMARS Study Group and BoReal study group and ABDOMIX Group and Groupe de travail sur la ventilation and Groupe de Recherche en Reanimation Respiratoire du patient d’Onc-hématologie and Groupe RMM and Université Paris 6 —Pierre et Marie Curie and Institut National pour la Santé et la Recherche Médicale, UMRS1158, Paris and Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologie and ABLE French Investigators and ENCEPHALITICA Study Group and Septiflux trial Group and CRICS Network and OutcomeRéa and Committee of young intensivists of the French Society for Intensive Care Medicine (FICS) and NutriSIP and CNER DESC réanimation grand ouest and Phase Angle Project Investigators
Annals of Intensive Care, ISSN 2110-5820, 6/2016, Volume 6, Issue S1, pp. 1 - 236
PHYSICIANS ABSTRACTSO1 Impact of tracheal cuff shape on microaspiration of gastric contents in intubated critically ill patients: a multicenter randomized... 
Intensive / Critical Care Medicine | Emergency Medicine | Anesthesiology | Medicine & Public Health | Life Sciences | Human health and pathology
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2. Full Text Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study
by Moreau, Philippe, Prof and Pylypenko, Halyna, MD and Grosicki, Sebastian, MD and Karamanesht, Ievgenii, MD and Leleu, Xavier, MD and Grishunina, Maria, MD and Rekhtman, Grigoriy, MD and Masliak, Zvenyslava, MD and Robak, Tadeusz, Prof and Shubina, Anna, MD and Arnulf, Bertrand, MD and Kropff, Martin, MD and Cavet, James, MBBS and Esseltine, Dixie-Lee, MD and Feng, Huaibao, PhD and Girgis, Suzette, PhD and van de Velde, Helgi, MD and Deraedt, William, MSc and Harousseau, Jean-Luc, Prof
Lancet Oncology, The, ISSN 1470-2045, 2011, Volume 12, Issue 5, pp. 431 - 440
Summary Background Intravenous injection is the standard administration route of bortezomib; however, subcutaneous administration is an important alternative.... 
Hematology, Oncology and Palliative Medicine | IMPACT | THERAPY | PLUS DEXAMETHASONE | ONCOLOGY | EXTENDED FOLLOW-UP | APEX TRIAL | REFRACTORY MYELOMA | TIME | II TRIAL | STEM-CELL TRANSPLANTATION | COMBINATION | South America | Recurrence | Peripheral Nervous System Diseases - chemically induced | Humans | Middle Aged | Pyrazines - administration & dosage | Boronic Acids - adverse effects | Male | Multiple Myeloma - ethnology | Antineoplastic Agents - administration & dosage | Multiple Myeloma - drug therapy | Antineoplastic Agents - adverse effects | Injections, Subcutaneous | Aged, 80 and over | Protease Inhibitors - administration & dosage | Protease Inhibitors - adverse effects | Adult | Boronic Acids - administration & dosage | Blood Cells - drug effects | Multiple Myeloma - blood | Bortezomib | Drug Administration Schedule | Europe | Kaplan-Meier Estimate | Treatment Outcome | Disease-Free Survival | Multiple Myeloma - pathology | Asia | Pyrazines - adverse effects | Aged | Infusions, Intravenous | Neoplasm Staging | Medical colleges | Medical research | Relapse | Multiple myeloma | Medicine, Experimental | Diseases | Index Medicus
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3. Full Text New hope for relapsed and refractory multiple myeloma
by Leleu, Xavier
Lancet Oncology, The, ISSN 1470-2045, 2013, Volume 14, Issue 11, pp. 1028 - 1029
Hematology, Oncology and Palliative Medicine | SURVIVAL | LENALIDOMIDE | BORTEZOMIB | CC-4047 | ONCOLOGY | Multiple Myeloma - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Humans | Salvage Therapy | Neoplasm Recurrence, Local - drug therapy | Female | Male | Drug Resistance, Neoplasm - drug effects | Relapse | Multiple myeloma | Diseases | Index Medicus
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4. Full Text A key to the quest?
by Leleu, Xavier
Blood, ISSN 0006-4971, 10/2014, Volume 124, Issue 14, pp. 2162 - 2163
MULTIPLE-MYELOMA | ONCOGENE | AKT | HEMATOLOGY | CANCER | KINASE | Protein Kinase Inhibitors - pharmacokinetics | Protein Kinase Inhibitors - administration & dosage | Thiophenes - pharmacokinetics | Multiple Myeloma - drug therapy | Pyrazoles - administration & dosage | Humans | Female | Male | Thiophenes - administration & dosage | Proto-Oncogene Proteins c-akt - metabolism | Pyrazoles - pharmacokinetics | Index Medicus | Abridged Index Medicus
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5. Full Text Lenalidomide, Bortezomib, and Dexamethasone with Transplantation for Myeloma
by Attal, Michel and Lauwers-Cances, Valerie and Hulin, Cyrille and Leleu, Xavier and Caillot, Denis and Escoffre, Martine and Arnulf, Bertrand and Macro, Margaret and Belhadj, Karim and Garderet, Laurent and Roussel, Murielle and Payen, Catherine and Mathiot, Claire and Fermand, Jean P and Meuleman, Nathalie and Rollet, Sandrine and Maglio, Michelle E and Zeytoonjian, Andrea A and Weller, Edie A and Munshi, Nikhil and Anderson, Kenneth C and Richardson, Paul G and Facon, Thierry and Avet-Loiseau, Hervé and Harousseau, Jean-Luc and Moreau, Philippe and IFM 2009 Study
The New England Journal of Medicine, ISSN 0028-4793, 04/2017, Volume 376, Issue 14, pp. 1311 - 1320
In this trial, 700 patients with myeloma were randomly assigned to receive RVD therapy (lenalidomide, bortezomib, and dexamethasone) with or without autologous... 
DIAGNOSED MULTIPLE-MYELOMA | MEDICINE, GENERAL & INTERNAL | PHASE-III | AUTOLOGOUS TRANSPLANTATION | DARATUMUMAB MONOTHERAPY | INITIAL TREATMENT | FOLLOW-UP | PREDNISONE PLUS THALIDOMIDE | RANDOMIZED CONTROLLED-TRIAL | STEM-CELL TRANSPLANTATION | ELDERLY-PATIENTS | Humans | Middle Aged | Salvage Therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Dexamethasone - adverse effects | Induction Chemotherapy | Male | Transplantation, Autologous | Stem Cell Transplantation | Thalidomide - analogs & derivatives | Multiple Myeloma - drug therapy | Adult | Female | Maintenance Chemotherapy | Thalidomide - adverse effects | Dexamethasone - administration & dosage | Lenalidomide | Kaplan-Meier Estimate | Combined Modality Therapy | Thalidomide - administration & dosage | Disease-Free Survival | Bortezomib - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Bortezomib - adverse effects | Aged | Usage | Care and treatment | Bortezomib | Dexamethasone | Patient outcomes | Multiple myeloma | Transplantation of organs, tissues, etc | Dosage and administration | Autografts | Gastrointestinal tract diseases | Minimal residual disease | Stem cell transplantation | Peripheral neuropathy | Patients | Chemotherapy | Melphalan | Thromboembolism | Neutropenia | Index Medicus | Abridged Index Medicus | Life Sciences | Cancer
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6. Full Text Occupational risk factors for COPD: A case-control study
by Kraïm-Leleu, Marie and Lesage, Francois-Xavier and Drame, Moustapha and Lebargy, Francois and Deschamps, Frédéric
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, pp. e0158719 - e0158719
Objectives The aim of this research was to examine the occupational risk factors for Chronic Obstructive Pulmonary Diseases (COPD) in a range of occupations.... 
DEFINITION | POPULATION | OBSTRUCTIVE PULMONARY-DISEASE | NONSMOKERS | DUST | MULTIDISCIPLINARY SCIENCES | PREVALENCE | ASSOCIATION | BURDEN | EXPOSURE | EPIDEMIOLOGY | France - epidemiology | Humans | Middle Aged | Risk Factors | Logistic Models | Male | Pulmonary Disease, Chronic Obstructive - physiopathology | Pulmonary Disease, Chronic Obstructive - epidemiology | Case-Control Studies | Occupational Diseases - chemically induced | Occupational Diseases - physiopathology | Occupational Exposure - analysis | Smoking - epidemiology | Pulmonary Disease, Chronic Obstructive - chemically induced | Aged, 80 and over | Adult | Female | Aged | Occupational Diseases - epidemiology | Medicine, Experimental | Medical research | Lung diseases, Obstructive | Exercise | Risk factors | Physical activity | Aluminum | Occupations | Brushing | Iron | Epidemiology | Mining | Ferrous alloys | Smelters | Chronic obstructive pulmonary disease | Resins | Outdoor air quality | Alloy cast iron | Lung diseases | Cast iron | Health risks | Regression analysis | Risk analysis | Casting machines | Heavy metals | Cores | Occupation | Tuberculosis | Compressed air | Workers | Obstructive lung disease | Synthetic resins | Health risk assessment | Smoking | Index Medicus
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7. Full Text Mortality after surgery in Europe: a 7 day cohort study
by Pearse, Rupert M, Dr and Moreno, Rui P, Prof and Bauer, Peter, Prof and Pelosi, Paolo, Prof and Metnitz, Philipp, Prof and Spies, Claudia, Prof and Vallet, Benoit, Prof and Vincent, Jean-Louis, Prof and Hoeft, Andreas, Prof and Rhodes, Andrew, FRCP and Trial Grp European Soc Intensive and Trial Grp European Soc and European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology
Lancet, The, ISSN 0140-6736, 2012, Volume 380, Issue 9847, pp. 1059 - 1065
Summary Background Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and... 
Internal Medicine | POPULATION | MEDICINE, GENERAL & INTERNAL | NONCARDIAC SURGERY | POSTOPERATIVE COMPLICATIONS | CANCER-SURGERY | LONG-TERM SURVIVAL | SURGICAL QUALITY IMPROVEMENT | RISK | INPATIENT SURGERY | CRITICAL-CARE | MAJOR SURGERY | Critical Care - statistics & numerical data | Hospital Mortality | Surgical Procedures, Operative - mortality | Humans | Middle Aged | Europe - epidemiology | Hospitalization - statistics & numerical data | Male | Treatment Outcome | Postoperative Care - methods | Adult | Female | Postoperative Care - statistics & numerical data | Aged | Length of Stay - statistics & numerical data | Cohort Studies | Austria | Demographic aspects | Mortality | United Kingdom | Portugal | Postoperative care | Health aspects | Risk factors | Index Medicus | Abridged Index Medicus
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