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asthma (254) 254
humans (223) 223
male (143) 143
index medicus (126) 126
allergy (122) 122
female (122) 122
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children (107) 107
child (103) 103
allergy and immunology (100) 100
abridged index medicus (88) 88
article (85) 85
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asthma - drug therapy (74) 74
asthma in children (69) 69
respiratory system (64) 64
risk factors (60) 60
studies (57) 57
asthma - physiopathology (53) 53
adult (52) 52
age (52) 52
childhood asthma (52) 52
infant (51) 51
pediatrics (50) 50
adolescent (45) 45
animals (44) 44
asthma - genetics (43) 43
allergies (39) 39
asthma - immunology (39) 39
drug therapy (38) 38
health aspects (37) 37
inhaled corticosteroids (37) 37
medical colleges (37) 37
asthma - diagnosis (34) 34
corticosteroids (34) 34
administration, inhalation (33) 33
public health (33) 33
respiratory syncytial virus (33) 33
rhinovirus (33) 33
double-blind method (32) 32
fluticasone (31) 31
treatment outcome (31) 31
research (30) 30
wheezing (30) 30
children & youth (28) 28
respiratory tract diseases (28) 28
atopy (27) 27
critical care medicine (27) 27
medicine, general & internal (27) 27
rats (27) 27
asthma - epidemiology (26) 26
asthma - etiology (26) 26
clinical trials (26) 26
infections (26) 26
inflammation (25) 25
disease (24) 24
infant, newborn (24) 24
middle aged (24) 24
persistent asthma (24) 24
viral infections (24) 24
viruses (24) 24
budesonide (23) 23
genetics (23) 23
respiratory tract infections - virology (23) 23
risk (23) 23
analysis (22) 22
cohort studies (22) 22
therapy (22) 22
anti-asthmatic agents - therapeutic use (21) 21
biomarkers (21) 21
albuterol - analogs & derivatives (20) 20
early-life (20) 20
lung-function (20) 20
polymorphism, single nucleotide (20) 20
prospective studies (20) 20
nitric oxide (19) 19
salmeterol (19) 19
allergens (18) 18
association (18) 18
asthma - prevention & control (18) 18
hypersensitivity (18) 18
illnesses (18) 18
medicine (18) 18
montelukast (18) 18
albuterol - therapeutic use (17) 17
allergic sensitization (17) 17
bronchodilator agents - administration & dosage (17) 17
care and treatment (17) 17
genetic predisposition to disease (17) 17
genotype (17) 17
phenotype (17) 17
preschool-children (17) 17
salmeterol xinafoate (17) 17
young-children (17) 17
exhaled nitric-oxide (16) 16
genotype & phenotype (16) 16
time factors (16) 16
wheeze (16) 16
adrenal cortex hormones - therapeutic use (15) 15
adrenergic beta-agonists - therapeutic use (15) 15
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1. Asthma prevention
by Busse, W. W. (William W.) and Lemanske, Robert F
2005, Lung biology in health and disease, ISBN 0824754093, Volume 195, xviii, 661
Collecting research from leading specialists in the field, this reference contains the latest studies on the genetic and environmental origins, pathogenesis,... 
Prevention | Asthma in children | Asthma | Allergology & Clinical Immunology | Pulmonary Medicine | Asthma - Prevention
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2. Full Text Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial
by Israel, Elliot and Chinchilli, Vernon M and Ford, Jean G and Boushey, Homer A and Cherniack, Reuben and Craig, Timothy J and Deykin, Aaron and Fagan, Joanne K and Fahy, John V and Fish, James and Kraft, Monica and Kunselman, Susan J and Lazarus, Stephen C and Lemanske, Robert F and Liggett, Stephen B and Martin, Richard J and Mitra, Nandita and Peters, Stephen P and Silverman, Eric and Sorkness, Christine A and Szefler, Stanley J and Wechsler, Michael E and Weiss, Scott T and Drazen, Jeffrey M and Natl Heart Lung Blood Inst Asthma and National Heart, Lung, and Blood Institute's Asthma Clinical Research Network
The Lancet, ISSN 0140-6736, 10/2004, Volume 364, Issue 9444, pp. 1505 - 1512
The issue of whether regular use of an inhaled β -adrenergic agonist worsens airflow and clinical outcomes in asthma is controversial. Retrospective studies... 
MILD | BETA-ADRENERGIC RECEPTOR HAPLOTYPES | MODERATE | MEDICINE, GENERAL & INTERNAL | POLYMORPHISMS | INHALED BETA-AGONIST | EXACERBATIONS | Single-Blind Method | Asthma - physiopathology | Double-Blind Method | Drug Administration Schedule | Receptors, Adrenergic, beta-2 - genetics | Humans | Middle Aged | Administration, Inhalation | Genotype | Male | Asthma - drug therapy | Asthma - genetics | Polymorphism, Genetic | Cross-Over Studies | Forced Expiratory Volume | Adolescent | Adrenergic beta-Agonists - administration & dosage | Albuterol - administration & dosage | Metered Dose Inhalers | Adult | Female | Peak Expiratory Flow Rate | Dosage and administration | Albuterol | Drug therapy | Asthma | Patient outcomes | Genetic aspects | Research | Health aspects | Genetic polymorphisms | Clinical trials | Genotype & phenotype | Prescription drugs | Medical treatment | Drugs | Flow rates | Homozygosity | Glycine | Patients | Gene polymorphism | Air flow | Airway management | Randomization | Motivation | Arginine | Flow velocity | Adrenergic receptors | Genotypes | Polymorphism
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3. Clinical immunology
by Graziano, Frank M and Lemanske, Robert F
1989, ISBN 9780683035513, xiii, 319
Immunologic diseases | Immunology
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4. Full Text In person with: Robert F. Lemanske, Jr., MD, FAAAAI
by Lemanske Jr, Robert F
The Journal of allergy and clinical immunology, 05/2013, Volume 131, Issue 5, p. 34A
Asthma - diagnosis | Societies, Medical | Asthma - prevention & control | United States | Humans | Allergy and Immunology | Adult | Asthma - therapy | Clinical Trials as Topic | Child | Periodicals as Topic
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5. Full Text Asthma
by Busse, William W and Lemanske Jr, Robert F
New England Journal of Medicine, ISSN 0028-4793, 02/2001, Volume 344, Issue 5, pp. 350 - 362
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6. Full Text Bronchiolitis to Asthma: A Review and Call for Studies of Gene-Virus Interactions in Asthma Causation
by Singh, Anne Marie and Moore, Paul E and Gern, James E and Lemanske, Robert F., Jr and Hartert, Tina V
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 01/2007, Volume 175, Issue 2, pp. 108 - 119
Viral infections are important causes of asthma exacerbations in children, and lower respiratory tract infections (LRTIs), caused by viruses such as... 
Genetics | Respiratory syncytial virus | Asthma | Bronchiolitis | Rhinovirus | RISK-FACTORS | ENVIRONMENT INTERACTIONS | asthma | rhinovirus | HLA-G | bronchiolitis | genetics | INTERFERON-GAMMA | RESPIRATORY SYSTEM | RSV BRONCHIOLITIS | HOSPITAL ADMISSION | RESPIRATORY-SYNCYTIAL-VIRUS | AIRWAY HYPERRESPONSIVENESS | RHINOVIRUS INFECTION | SUSCEPTIBILITY LOCUS | respiratory syncytial virus | CRITICAL CARE MEDICINE | Genetic Predisposition to Disease - etiology | Bronchiolitis, Viral - genetics | Animals | Humans | Environment | Asthma - virology | Respiratory Sounds - etiology | Child | Asthma - genetics | Bronchiolitis, Viral - complications | Bronchiolitis, Viral - immunology
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7. Full Text Classifying Asthma Severity in Children: Mismatch Between Symptoms, Medication Use, and Lung Function
by Bacharier, Leonard B and Strunk, Robert C and Mauger, David and White, Deborah and Lemanske, Robert F., Jr and Sorkness, Christine A
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 08/2004, Volume 170, Issue 4, pp. 426 - 432
Current guidelines for asthma care categorize asthma severity based on the frequency of asthma symptoms, medication use, and lung function measures. The... 
Severity | Lung function | Children | Asthma | severity | VARIABILITY | lung function | EXPIRATORY FLOW | children | RESPIRATORY SYSTEM | asthma | PULMONARY-FUNCTION | AIRWAY-OBSTRUCTION | CHILDHOOD ASTHMA | CRITICAL CARE MEDICINE | Prospective Studies | Age Factors | Asthma - physiopathology | Anti-Asthmatic Agents - therapeutic use | Humans | Child, Preschool | Male | Asthma - drug therapy | Adolescent | Sex Factors | Female | Respiratory Function Tests | Asthma - classification | Child
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8. Full Text Early Life Risk Factors for Asthma at Early Adulthood
by Peloza, David and Evans, Michael D and Gangnon, Ronald E and Gern, James E and Lemanske, Robert F and Jackson, Daniel J
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 02/2019, Volume 143, Issue 2, pp. AB78 - AB78
Tobacco smoke | Respiratory syncytial virus | Risk analysis | Risk factors | Age | Asthma
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9. Full Text Role of viral respiratory infections in asthma and asthma exacerbations
by Busse, William W, Prof and Lemanske, Robert F, MD and Gern, James E, MD
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9743, pp. 826 - 834
Summary Viral respiratory tract infections are common and usually selflimited illnesses. For patients at risk of asthma, or with existing asthma, viral... 
Internal Medicine | IDENTIFIED HUMAN RHINOVIRUS | RESPONSES | MEDICINE, GENERAL & INTERNAL | SYNCYTIAL VIRUS-INFECTION | EARLY-LIFE | EPITHELIAL-CELLS | RISK | 1ST 6 YEARS | ILLNESSES | TRACT INFECTIONS | CHILDREN | Genetic Predisposition to Disease | Asthma - physiopathology | Antiviral Agents - therapeutic use | Dendritic Cells - immunology | Humans | Risk Factors | Child, Preschool | Infant | Inflammation | Virus Diseases - complications | Respiratory System - virology | Virus Diseases - drug therapy | Asthma - immunology | Respiratory System - physiopathology | Respiratory Tract Infections - complications | Asthma - virology | Respiratory Sounds | Respiratory Tract Infections - virology | Child | Cytokines - biosynthesis | Prevention | Respiratory tract infections | Complications and side effects | Care and treatment | Diagnosis | Research | Risk factors | Asthma | Studies | Disease | Pathogenesis | Viruses | Family medical history | Grants | Gene expression | Viral infections | Age
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10. Full Text Asthma in Siblings and Risk for Childhood Asthma
by Peloza, David L and Evans, Michael D and Gern, James E and Lemanske, Robert F and Jackson, Daniel J
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 02/2018, Volume 141, Issue 2, pp. AB9 - AB9
Results Rates of asthma according to family history at ages 6-13 years were 19-23%, 27-31%, 36-40%, and 40-49% for children without family history of asthma,... 
Disease management | Children | Asthma | Siblings
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11. Full Text Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis—PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology
by Muraro, Antonella, MD and Lemanske, Robert F., MD and Hellings, Peter W., MD and Akdis, Cezmi A., MD and Bieber, Thomas, MD and Casale, Thomas B., MD and Jutel, Marek, MD and Ong, Peck Y., MD and Poulsen, Lars K., PhD and Schmid-Grendelmeier, Peter, MD and Simon, Hans-Uwe, MD and Seys, Sven F., PhD and Agache, Ioana, MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 137, Issue 5, pp. 1347 - 1358
In this consensus document we summarize the current knowledge on major asthma, rhinitis, and atopic dermatitis endotypes under the auspices of the PRACTALL... 
Allergy and Immunology | phenotype | allergic skin disease | Precision medicine | allergic asthma | endotype | personalized care | allergic rhinitis | biomarker | Key words Precision medicine | CORTICOSTEROID RESPONSIVENESS | IL-13 EXPRESSION | SURROGATE END-POINTS | SEVERE EOSINOPHILIC ASTHMA | BARRIER FUNCTION | IMMUNOLOGY | CHRONIC RHINOSINUSITIS | ALLERGY | INTERNATIONAL CONSENSUS | DOUBLE-BLIND | GENE-EXPRESSION | EVALUATE SAFETY | Rhinitis - immunology | Dermatitis, Atopic - drug therapy | Europe | Humans | Asthma - immunology | Dermatitis, Atopic - immunology | Societies, Scientific | Asthma - drug therapy | Respiratory System - immunology | Rhinitis - drug therapy | Precision Medicine | Skin - immunology | Food allergy | Care and treatment | Atopic dermatitis | Asthma | Food allergies | Disease | Cytokines | Inflammation | Metabolism | Patients | Blood | Quality of life | Medicine | Genotype & phenotype | Immunology | Biomarkers | Volatile organic compounds--VOCs
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12. Full Text Asthma: Clinical expression and molecular mechanisms
by Lemanske, Robert F., MD and Busse, William W., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 125, Issue 2, pp. S95 - S102
Asthma is a complex disorder that displays heterogeneity and variability in its clinical expression both acutely and chronically. This heterogeneity is... 
Allergy and Immunology | allergen | treatment | inception | respiratory syncytial virus | rhinovirus | prevention | Asthma | exacerbation | EXHALED BREATH CONDENSATE | INHALED CORTICOSTEROIDS | AIRWAY INFLAMMATION | IMMUNOLOGY | CHILDHOOD ASTHMA | PRESCHOOL-CHILDREN | DIFFICULT ASTHMA | OBSTRUCTIVE PULMONARY-DISEASE | ALLERGY | LUNG-FUNCTION DECLINE | ACTING BETA-AGONISTS | YOUNG-CHILDREN | Asthma - diagnosis | Immunization | Asthma - physiopathology | Humans | Risk Factors | Disease Progression | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Allergens - immunology | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Airway Obstruction - immunology | Asthma - immunology | Adult | Asthma - therapy | Child | Asthma - epidemiology | Practice Guidelines as Topic | Gastroesophageal reflux | Medical colleges | Corticosteroids | Health aspects | Studies | Disease prevention | Child development | Nitric oxide | Drug therapy | Viral infections | Age | Prevention | Exacerbation | Respiratory syncytial virus | Treatment | Inception | Rhinovirus | Allergen
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13. Full Text Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome
by Lötvall, Jan, MD and Akdis, Cezmi A., MD and Bacharier, Leonard B., MD and Bjermer, Leif, MD and Casale, Thomas B., MD and Custovic, Adnan, MD and Lemanske, Robert F., MD and Wardlaw, Andrew J., MD and Wenzel, Sally E., MD and Greenberger, Paul A., MD and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Krefting Research Centre and Sahlgrenska Academy
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 127, Issue 2, pp. 355 - 360
It is increasingly clear that asthma is a complex disease made up of number of disease variants with different underlying pathophysiologies. Limited knowledge... 
Allergy and Immunology | phenotype | epidemiology | cluster analysis | endotype | pathophysiology | Asthma | RISK | PHENOTYPES | IMMUNOLOGY | CROSS-COUNTRY SKIERS | CLUSTER-ANALYSIS | PRESCHOOL-CHILDREN | ALLERGY | INFLAMMATION | BIRTH COHORT | BIOPSIES | ONSET | LONG | Invasive Pulmonary Aspergillosis | Phenotype | Asthma - physiopathology | Humans | Asthma - classification | Asthma - drug therapy | Aspergillosis, Allergic Bronchopulmonary - etiology | Medical colleges | Analysis | Mycoses | Respiratory agents | Cross infection | Nosocomial infections | Studies | Obesity | Genotype & phenotype | Disease | Biomarkers | Drug therapy | Epidemiology | Asthma; endotype; phenotype; cluster analysis; pathophysiology; epidemiology | Immunology in the medical area | Immunologi inom det medicinska området
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14. Full Text Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations
by Kloepfer, Kirsten M., MD, MS and Lee, Wai Ming, PhD and Pappas, Tressa E., BS and Kang, Theresa J., BS and Vrtis, Rose F., BS and Evans, Michael D., MS and Gangnon, Ronald E., PhD and Bochkov, Yury A., PhD and Jackson, Daniel J., MD and Lemanske, Robert F., MD and Gern, James E., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 133, Issue 5, pp. 1301 - 1307.e3
Background Detection of either viral or bacterial pathogens is associated with wheezing in children; however, the influence of both bacteria and viruses on... 
Allergy and Immunology | bacteria | asthma | Rhinovirus | STREPTOCOCCUS-PNEUMONIAE | AIRWAY | ALLERGY | MORAXELLA-CATARRHALIS | INFLUENZA-VIRUS | IMMUNOLOGY | YOUNG-CHILDREN | PCR | Asthma - microbiology | Humans | Child, Preschool | Male | Picornaviridae Infections - microbiology | Bacteria - genetics | Asthma - genetics | Bacteria - isolation & purification | Bacterial Infections - genetics | DNA, Bacterial - genetics | Asthma - complications | Polymerase Chain Reaction | Female | Picornaviridae Infections - genetics | Asthma - virology | Child | Bacterial Infections - microbiology | Medical colleges | Bacteria | Health aspects | Public health | Medical informatics | Asthma | Illnesses | Sleep | Colleges & universities | Viruses | Viral infections | Deoxyribonucleic acid--DNA | Streptococcus infections
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15. Full Text Trajectories of childhood immune development and respiratory health relevant to asthma and allergy
by Tang, Howard H. F and Tang, Howard Hf and Teo, Shu Mei and Teo, Shu Mei and Belgrave, Danielle C. M and Belgrave, Danielle Cm and Evans, Michael D and Jackson, Daniel J and Brozynska, Marta and Kusel, Merci Mh and Kusel, Merci M. H and Johnston, Sebastian L and Gern, James E and Gern, James E and Lemanske, Robert F and Simpson, Angela and Simpson, Angela and Custovic, Adnan and Sly, Peter D and Sly, Peter D and Holt, Patrick G and Holt, Patrick G and Holt, Kathryn E and Holt, Kathryn E and Inouye, Michael and Inouye, Michael
eLife, ISSN 2050-084X, 10/2018, Volume 7
Events in early life contribute to subsequent risk of asthma; however, the causes and trajectories of childhood wheeze are heterogeneous and do not always... 
computational biology | systems biology | immune development | respiratory disease | bioinformatics | allergy | human | Asthma - physiopathology | Humans | Risk Factors | Child, Preschool | Hypersensitivity - immunology | Infant | Male | Immune System - growth & development | Australia - epidemiology | Respiratory System - growth & development | Hypersensitivity - physiopathology | Asthma - immunology | Female | Respiratory System - physiopathology | Hypersensitivity - epidemiology | Child | Respiratory System - immunology | Asthma - epidemiology | Cluster analysis | Risk groups | Pathogenesis | Genomics | Hypersensitivity | Infections | Allergic diseases | Allergies | Atopy | Asthma | Datasets | Variables | Phenotyping | Classification | Children | Hygiene | Age | Public health
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