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Cell, ISSN 0092-8674, 2011, Volume 146, Issue 6, pp. 904 - 917
Journal Article
Cancer Cell, ISSN 1535-6108, 2010, Volume 18, Issue 4, pp. 316 - 328
Epigenetic alterations have been increasingly implicated in oncogenesis. Analysis of mutants suggests that Polycomb and SWI/SNF complexes can serve... 
GENOMIC INSTABILITY | DEVELOPMENTAL REGULATORS | CHROMATIN | ONCOLOGY | EMBRYONIC STEM-CELLS | TUMOR-SUPPRESSOR GENE | GROUP PROTEIN EZH2 | RHABDOID TUMOR | SELF-RENEWAL | CANCER | DROSOPHILA | Analysis | Stem cells | Tumors | Polycomb | SNF | SWI | SNF5 | oncogenesis | EZH2
Journal Article
Cancer Cell, ISSN 1535-6108, 2008, Volume 14, Issue 5, pp. 355 - 368
We created a mouse model wherein conditional expression of an Mll-AF4 fusion oncogene induces B precursor acute lymphoblastic (ALL) or acute myeloid leukemias... 
CELLCYCLE | METHYLTRANSFERASE | MLL TRANSLOCATIONS | CHROMATIN | ONCOLOGY | ROLES | ACUTE LYMPHOBLASTIC-LEUKEMIA | GENE-EXPRESSION | CLASSIFICATION | TARGETS | MODEL | TRANSCRIPTIONAL ELONGATION | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Oligonucleotide Array Sequence Analysis | Histones - chemistry | Homeodomain Proteins - metabolism | Humans | Protein Methyltransferases - genetics | Male | Gene Expression Profiling | Protein Methyltransferases - metabolism | Oncogene Proteins, Fusion - physiology | Flow Cytometry | Methyltransferases - physiology | Chromatin Immunoprecipitation | Myeloid-Lymphoid Leukemia Protein - physiology | Biomarkers, Tumor - metabolism | Female | Integrases - metabolism | Transcription, Genetic | Cell Differentiation | Lysine - metabolism | Principal Component Analysis | Histone-Lysine N-Methyltransferase | Leukemia, Myeloid, Acute - pathology | RNA, Small Interfering - pharmacology | Cells, Cultured | Immunophenotyping | Mice, Transgenic | Gene Expression Regulation, Leukemic | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Lysine - genetics | Animals | Histones - genetics | Methyltransferases - antagonists & inhibitors | Gene Rearrangement | Biomarkers, Tumor - genetics | Mice | Histones - metabolism | Lysine - chemistry | Methylation | Leukemia, Myeloid, Acute - genetics | Gene expression | Lysine | Analysis | Transferases | Leukemia
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 2014, Volume 15, Issue 4, pp. 373 - 383
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 21, pp. E4184 - E4192
Journal Article