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animals (4) 4
life sciences & biomedicine (4) 4
male (4) 4
radiology, nuclear medicine & medical imaging (4) 4
rats (4) 4
rats, wistar (4) 4
science & technology (4) 4
contrast media - pharmacokinetics (3) 3
brain - metabolism (2) 2
cerebrospinal fluid (2) 2
contrast agent (2) 2
contrast agents (2) 2
contrast media - administration & dosage (2) 2
dose-response relationship, drug (2) 2
gadolinium (2) 2
gadolinium - administration & dosage (2) 2
gadolinium - pharmacokinetics (2) 2
magnetic resonance imaging (2) 2
mass spectrometry (2) 2
models, animal (2) 2
mri (2) 2
original (2) 2
analysis of variance (1) 1
animal experiment (1) 1
attenuation (1) 1
blood (1) 1
blood-brain barrier - physiology (1) 1
bone and bones - drug effects (1) 1
bone and bones - metabolism (1) 1
brain (1) 1
brain - anatomy & histology (1) 1
brain - diagnostic imaging (1) 1
brain - drug effects (1) 1
brain - ultrastructure (1) 1
cerebrospinal fluid - metabolism (1) 1
colony-stimulating factor (1) 1
contrast media (1) 1
contrast media - adverse effects (1) 1
contrast media - chemistry (1) 1
dentate nucleus (1) 1
diffusion magnetic resonance imaging - methods (1) 1
drug administration schedule (1) 1
flow (1) 1
gadobutrol (1) 1
gadodiamide (1) 1
gadolinium - adverse effects (1) 1
gadolinium dtpa - administration & dosage (1) 1
gadolinium dtpa - adverse effects (1) 1
gadolinium dtpa - pharmacokinetics (1) 1
gadolinium retention (1) 1
gadopentetate dimeglumine (1) 1
gadoteridol (1) 1
gbca (1) 1
gehirn (1) 1
globus pallidus (1) 1
heterocyclic compounds - administration & dosage (1) 1
heterocyclic compounds - adverse effects (1) 1
heterocyclic compounds - pharmacokinetics (1) 1
histology (1) 1
image enhancement - methods (1) 1
inductively coupled plasma (1) 1
infiltration (1) 1
injections, intravenous (1) 1
iodine retention (1) 1
iohexol - analogs & derivatives (1) 1
iohexol - chemistry (1) 1
iohexol - pharmacokinetics (1) 1
ioxaglic acid - pharmacokinetics (1) 1
kernspintomographie (1) 1
kidney - drug effects (1) 1
kidney - metabolism (1) 1
kinetics (1) 1
kinetik (1) 1
kontrastmittel (1) 1
liquor cerebrospinalis (1) 1
macrocyclic compounds - administration & dosage (1) 1
magnetic resonance imaging - methods (1) 1
marketing (1) 1
mass spectroscopy (1) 1
massenspektrometrie mit induktiv gekoppeltem plasma (1) 1
muscle, skeletal - drug effects (1) 1
muscle, skeletal - metabolism (1) 1
organometallic compounds - administration & dosage (1) 1
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original articles (1) 1
osmolality (1) 1
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oxygen - blood (1) 1
penetration (1) 1
physicochemical properties (1) 1
pons (1) 1
radiology nuclear medicine and imaging (1) 1
ratte (1) 1
reference values (1) 1
renal oxygenation (1) 1
reproducibility of results (1) 1
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1. Full Text Penetration and distribution of gadolinium-based contrast agents into the cerebrospinal fluid in healthy rats: a potential pathway of entry into the brain tissue
by Jost, Gregor and Frenzel, Thomas and Lohrke, Jessica and Lenhard, Diana Constanze and Naganawa, Shinji and Pietsch, Hubertus
European radiology, ISSN 0938-7994, 07/2017, Volume 27, Issue 7, pp. 2877 - 2885
Brain | Gadolinium | Cerebrospinal fluid | Magnetic resonance imaging | Contrast media | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Brain - diagnostic imaging | Rats, Wistar | Gadolinium - pharmacokinetics | Contrast Media - pharmacokinetics | Magnetic Resonance Imaging - methods | Rats | Male | Reference Values | Brain - metabolism | Animals | Cerebrospinal Fluid - metabolism | Mass Spectrometry | Blood-Brain Barrier - physiology | Models, Animal | Mass spectrometry | Marketing | Mass spectroscopy | Blood | Flow | Contrast agents | Inductively coupled plasma | Penetration | Water analysis | Rodents | Attenuation | Colony-stimulating factor | Infiltration | Kinetics | Physicochemical properties | Index Medicus | Contrast Media
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2. Full Text Signal increase on unenhanced T1-weighted images in the rat brain after repeated, extended doses of gadolinium-based contrast agents comparison of linear and macrocyclic agents
by Jost, Gregor and Lenhard, Diana Constanze and Sieber, Martin Andrew and Lohrke, Jessica and Frenzel, Thomas and Pietsch, Hubertus
Investigative radiology, ISSN 0020-9996, 2016, Volume 51, Issue 2, pp. 83 - 89
Animal experiment | Pons | MRI | Contrast agent | GBCA | Gadolinium | Cerebrospinal fluid | Retention | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gadolinium - administration & dosage | Reproducibility of Results | Brain - anatomy & histology | Drug Administration Schedule | Rats, Wistar | Rats | Male | Dose-Response Relationship, Drug | Animals | Contrast Media - administration & dosage | Sensitivity and Specificity | Image Enhancement - methods | Macrocyclic Compounds - administration & dosage | Diffusion Magnetic Resonance Imaging - methods | Index Medicus | pons | cerebrospinal fluid | Original | contrast agent | retention | animal experiment | gadolinium
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3. Full Text Histology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents
by Lohrke, Jessica and Frisk, Anna-Lena and Frenzel, Thomas and Schöckel, Laura and Rosenbruch, Martin and Jost, Gregor and Lenhard, Diana Constanze and Sieber, Martin A and Nischwitz, Volker and Küppers, Astrid and Pietsch, Hubertus
Investigative radiology, ISSN 0020-9996, 03/2017, Volume 52, Issue 6, pp. 324 - 333
Gadodiamide | Gadobutrol | Gadolinium retention | MRI | Contrast agent | Gadoteridol | Globus pallidus | Histology | Dentate nucleus | Gadopentetate dimeglumine | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gadolinium - administration & dosage | Injections, Intravenous | Rats, Wistar | Gadolinium - pharmacokinetics | Contrast Media - pharmacokinetics | Male | Muscle, Skeletal - metabolism | Bone and Bones - drug effects | Brain - metabolism | Dose-Response Relationship, Drug | Contrast Media - adverse effects | Bone and Bones - metabolism | Contrast Media - administration & dosage | Mass Spectrometry | Muscle, Skeletal - drug effects | Brain - ultrastructure | Gadolinium DTPA - pharmacokinetics | Models, Animal | Gadolinium DTPA - administration & dosage | Retrospective Studies | Gadolinium DTPA - adverse effects | Heterocyclic Compounds - administration & dosage | Organometallic Compounds - adverse effects | Rodentia | Organometallic Compounds - pharmacokinetics | Rats | Gadolinium - adverse effects | Brain - drug effects | Animals | Heterocyclic Compounds - adverse effects | Skin - ultrastructure | Heterocyclic Compounds - pharmacokinetics | Skin - drug effects | Organometallic Compounds - administration & dosage | Index Medicus | gadolinium retention | histology | gadopentetate dimeglumine | gadobutrol | Original | globus pallidus | gadoteridol | contrast agent | dentate nucleus | gadodiamide
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4. Full Text The Effect of Iodinated Contrast Agent Properties on Renal Kinetics and Oxygenation
by Lenhard, Diana Constanze and Frisk, Anna-Lena and Lengsfeld, Philipp and Pietsch, Hubertus and Jost, Gregor
Investigative radiology, ISSN 0020-9996, 04/2013, Volume 48, Issue 4, pp. 175 - 182
Contrast agents | Iodine retention | Renal oxygenation | Urine viscosity | Osmolality | Vacuole formation | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Triiodobenzoic Acids - pharmacokinetics | Kidney - drug effects | Rats, Wistar | Ioxaglic Acid - pharmacokinetics | Contrast Media - pharmacokinetics | Iohexol - chemistry | Rats | Iohexol - pharmacokinetics | Male | Tomography, X-Ray Computed | Oxygen - blood | Magnetic Resonance Imaging | Kidney - metabolism | Animals | Osmolar Concentration | Analysis of Variance | Statistics, Nonparametric | Contrast Media - chemistry | Iohexol - analogs & derivatives | Triiodobenzoic Acids - chemistry | Index Medicus
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