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American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 04/2014, Volume 189, Issue 7, pp. 832 - 844
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2011, Volume 7, Issue 2, p. e1001284
Cell-free HIV-1 virions are poor stimulators of type I interferon (IFN) production. We examined here how HIV-infected cells are recognized by plasmacytoid... 
CD4(+) T-CELLS | RIG-I | MICROBIOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | ALPHA-INTERFERON | VIRAL-INFECTION | PLASMACYTOID DENDRITIC CELLS | ANTIVIRAL RESPONSES | VIROLOGY | ADAPTER PROTEIN | I INTERFERON-PRODUCTION | PARASITOLOGY | IFN-ALPHA | Virion - pathogenicity | Dendritic Cells - immunology | Humans | Glycoproteins - metabolism | Interferon Regulatory Factor-3 - genetics | HIV Infections - immunology | Lymphocytes - immunology | Lymphocytes - virology | Dendritic Cells - virology | Dendritic Cells - metabolism | Glycoproteins - genetics | Lymphocytes - metabolism | Toll-Like Receptor 7 - genetics | Interferon-alpha - metabolism | Toll-Like Receptor 7 - metabolism | HIV Seropositivity | HIV Infections - virology | RNA, Messenger - genetics | Cells, Cultured | Hematopoietic Stem Cells - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | HIV | Virus Replication | Interferon Regulatory Factor-3 - metabolism | HIV Infections - metabolism | Dendritic cells | Lymphocytes | Physiological aspects | Interferon | Research | HIV (Viruses) | Health aspects | Proteins | Medical research | Infections | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Immune system | Life Sciences | Microbiology and Parasitology | Acquired immune deficiency syndrome | AIDS | Human immunodeficiency virus
Journal Article
Annual Review of Immunology, ISSN 0732-0582, 4/2019, Volume 37, Issue 1, pp. 247 - 267
Recognition of foreign nucleic acids is the primary mechanism by which a type I interferon-mediated antiviral response is triggered. Given that human cells are... 
type I interferon | innate immunity | interferonopathies | MAMMALIAN DNA | RIG-I | IMMUNOLOGY | MITOCHONDRIAL-DNA | VIRAL-INFECTION | AICARDI-GOUTIERES-SYNDROME | REVERSE-TRANSCRIPTASE INHIBITORS | RNA EXOSOME | PROTEASOME SUBUNIT | MUTATIONS | AUTOIMMUNE-DISEASE | Interferon | Inflammation | Nucleic acids | Biological response modifiers
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2016, Volume 61, Issue 5, pp. 644 - 645
NLRP3 inflammasome activation is accompanied by induction of mitochondrial damage. In the current issue of , Zhong et al. describe an intracellular mechanism... 
IKK | MITOPHAGY | AUTOPHAGY | NF-KAPPA-B | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Mitochondria - metabolism | Animals | Inflammasomes - metabolism | NF-kappa B p50 Subunit - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Heat-Shock Proteins - metabolism | Mitochondrial DNA
Journal Article
Cell, ISSN 0092-8674, 2006, Volume 126, Issue 6, pp. 1121 - 1133
IL-17-producing T lymphocytes have been recently shown to comprise a distinct lineage of proinflammatory T helper cells, termed Th17 cells, that are major... 
LINEAGE COMMITMENT | IMMUNE | ISOLATED LYMPHOID FOLLICLES | TGF-BETA | INTERLEUKIN-17 | INFLAMMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCTION | IL-23 | TRANSCRIPTION FACTOR | AUTOIMMUNE ENCEPHALOMYELITIS | CELL BIOLOGY
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2018, Volume 379, Issue 23, pp. 2275 - 2277
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e52003
Neonates are highly susceptible to infectious diseases and defective antiviral pDC immune responses have been proposed to contribute to this phenomenon.... 
B-CELLS | CAPACITY | IMMUNITY | MULTIDISCIPLINARY SCIENCES | DEFECT | PREDENDRITIC CELLS | INFECTION | Tumor Necrosis Factor-alpha - metabolism | Dendritic Cells - immunology | Humans | Middle Aged | Toll-Like Receptor 9 - immunology | Flow Cytometry | Toll-Like Receptor 7 - immunology | CD5 Antigens - immunology | Tumor Necrosis Factor-alpha - immunology | Adult | CD2 Antigens - metabolism | Interleukin-12 Subunit p40 - immunology | Dendritic Cells - virology | Dendritic Cells - metabolism | Infant, Newborn | Chemokines - immunology | Interferon-alpha - metabolism | Interleukin-12 Subunit p40 - metabolism | Oligodeoxyribonucleotides - immunology | Toll-Like Receptor 7 - metabolism | Immunity, Innate - drug effects | Cells, Cultured | CD5 Antigens - metabolism | Interferon-alpha - immunology | Immunity, Innate - immunology | Adolescent | Chemokines - metabolism | Oligodeoxyribonucleotides - pharmacology | Toll-Like Receptor 9 - metabolism | CD2 Antigens - immunology | Infants (Newborn) | Antiviral agents | Disease susceptibility | Dendritic cells | HIV (Viruses) | Tumor necrosis factor | Neonates | Laboratories | Viruses | Infections | Blood | Cell adhesion & migration | Defects | Immunology | Cord blood | Human immunodeficiency virus--HIV | Toll-like receptors | Antigens | Cytomegalovirus | Immune response | TLR7 protein | Cytokines | Blood & organ donations | Phenotypic variations | Interleukin 12 | T cell receptors | Tumor necrosis factor-α | TLR9 protein | Virology | CD5 antigen | Infectious diseases | Interferon | Chemokines | Life Sciences | Adaptive immunology | HIV | Human immunodeficiency virus
Journal Article
ISSN 2211-1247, 2018
ECSIT is a mitochondrial complex I (CI)-associated protein that has been shown to regulate the production of mitochondrial reactive oxygen species (mROS)... 
Proteins | Mitochondria | Cytology | Glycolysis | Molecular biology | Macrophages
Journal Article
ISSN 1932-6203, 2016
Toll-like receptors (TLRs) are innate immune receptors that sense a variety of pathogen-associated molecular patterns (PAMPs) by interacting with them and... 
Pathology | Immune response--Molecular aspects | Toxoplasma gondii | Immunology | Microbiology | Protozoan diseases
Journal Article
CANCERS, ISSN 2072-6694, 09/2019, Volume 11, Issue 9, p. 1323
ABCB1 is a member of the ATP binding cassette transporter family and high ABCB1 activity is considered as a poor prognostic factor in acute myeloid leukemia... 
GEMTUZUMAB OZOGAMICIN | ABCB1 | NORMAL CYTOGENETICS | P-GLYCOPROTEIN EXPRESSION | DRUG-RESISTANCE | CYTARABINE | DAUNORUBICIN | prognosis | PSC-833 | acute myeloid leukemia | ONCOLOGY | MDR1 GENE-EXPRESSION | drug resistance | MULTIDRUG-RESISTANCE | GROUP-B | gene expression
Journal Article
Retrovirology, ISSN 1742-4690, 12/2011, Volume 8, Issue S1, pp. A239 - A239
Journal Article