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The New England Journal of Medicine, ISSN 0028-4793, 01/2016, Volume 374, Issue 1, pp. 54 - 61
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2015, Volume 112, Issue 40, pp. E5486 - E5495
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2015, Volume 47, Issue 9, pp. 1047 - 1055
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2018, Volume 24, Issue 5, pp. 679 - 690
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2017, Volume 49, Issue 10, pp. 1476 - 1486
Journal Article
Genetics in Medicine, ISSN 1098-3600, 07/2015, Volume 17, Issue 7, pp. 536 - 544
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1324 - 13
Journal Article
Journal Article
Science, ISSN 0036-8075, 09/2018, Volume 361, Issue 6409, p. 1324
Chen et al. (Reports, 17 February 2017, p. 752) highlight an important problem of sequencing artifacts caused by DNA damage at the time of sample processing.... 
INTEGRATED GENOMIC CHARACTERIZATION | LANDSCAPE | CARCINOMA | MULTIDISCIPLINARY SCIENCES | Artifacts | High-Throughput Nucleotide Sequencing | DNA Damage | Neoplasms - genetics | Sequence Analysis, DNA | Humans | DNA damage | Genomics | DNA | Causes of | Nucleotide sequencing | Analysis | DNA sequencing | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 2185 - 12
Treatment of chronic lymphocytic leukemia (CLL) has shifted from chemo-immunotherapy to targeted agents. To define the evolutionary dynamics induced by... 
B-CELL LYMPHOMA | TUMOR-MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | INITIAL THERAPY | RESISTANCE | CLONAL EVOLUTION | MUTATIONS | SEQUENCING DATA | SINGLE-ARM | GENOME | PROGRESSION | Pyrazoles - therapeutic use | Prognosis | Humans | Middle Aged | Male | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Clonal Evolution - genetics | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Rituximab - therapeutic use | Phospholipase C gamma - genetics | Aged, 80 and over | Adult | Female | Gene Expression Regulation, Neoplastic - drug effects | Molecular Targeted Therapy - methods | Pyrazoles - pharmacology | Signal Transduction | Clonal Evolution - drug effects | Down-Regulation | Treatment Outcome | Pyrimidines - pharmacology | Disease Progression | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Whole Exome Sequencing | Rituximab - pharmacology | Drug Resistance, Neoplasm - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Pyrimidines - therapeutic use | Agammaglobulinaemia Tyrosine Kinase | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - mortality | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Mutation | Longitudinal Studies | Drug Resistance, Neoplasm - drug effects | Protein-Tyrosine Kinases - antagonists & inhibitors | Lymphocyte receptors | Therapy | Energy metabolism | Chronic lymphatic leukemia | Transcription | Leukemia | Lymphatic leukemia | Metabolism | Drug resistance | Gene expression | Bruton's tyrosine kinase | Signaling | Lymphocytes B | Immunotherapy | Cell cycle | Evolution | Cancer | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2019, Volume 25, Issue 9, pp. 1415 - 1421
During cancer therapy, tumor heterogeneity can drive the evolution of multiple tumor subclones harboring unique resistance mechanisms in an individual... 
Therapy | Sequences | Autopsies | Data acquisition | Case reports | Heterogeneity | Alterations | Biopsy | Autopsy | Lesions | Target acquisition | Deoxyribonucleic acid--DNA | Tumors | Index Medicus
Journal Article