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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 6, pp. 2349 - 2354
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 31, pp. 11365 - 11370
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2015, Volume 112, Issue 40, pp. 12480 - 12485
Adult T-cell leukemia (ATL) develops in individuals infected with human T-cell lymphotropic virus-1 (HTLV-1). Presently there is no curative therapy for ATL.... 
Ruxolitinib|navitoclax | Adult t-cell leukemia|janus kinase | INTERLEUKIN-2 | MYELOFIBROSIS | ORAL JAK1 | MULTIDISCIPLINARY SCIENCES | PROLIFERATION | INTERFERON-ALPHA | navitoclax | JAK2 INHIBITOR | THERAPY | adult T-cell leukemia | Janus kinase | LYMPHOMA | MALIGNANCIES | ruxolitinib | Apoptosis - drug effects | Humans | STAT Transcription Factors - metabolism | Janus Kinases - metabolism | Flow Cytometry | Leukemia-Lymphoma, Adult T-Cell - drug therapy | bcl-X Protein - antagonists & inhibitors | Female | Antineoplastic Agents - pharmacology | Pyrazoles - pharmacology | Interleukin-2 - metabolism | Aniline Compounds - pharmacology | Cells, Cultured | Leukemia-Lymphoma, Adult T-Cell - pathology | Mice, SCID | Sulfonamides - pharmacology | Interleukin Receptor Common gamma Subunit - genetics | Blotting, Western | Mice, Knockout | Interleukin Receptor Common gamma Subunit - deficiency | Janus Kinases - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Leukemia-Lymphoma, Adult T-Cell - metabolism | Cell Line, Tumor | Mice, Inbred NOD | STAT Transcription Factors - antagonists & inhibitors | bcl-X Protein - metabolism | Interleukins | Leukemia | Physiological aspects | Cellular signal transduction | Observations | T cells | Health aspects | Biological Sciences
Journal Article
Scientific Reports, ISSN 2045-2322, 09/2015, Volume 5, Issue 1, p. 13891
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e90766
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 06/2017, Volume 25, Issue 6, pp. 1395 - 1407
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2015, Volume 112, Issue 40, p. 12480
  Adult T-cell leukemia (ATL) develops in individuals infected with human T-cell lymphotropic virus-1 (HTLV-1). Presently there is no curative therapy for ATL.... 
Cell growth | Cytokines | Leukemia | Gene expression | Tumors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2014, Volume 111, Issue 31, p. 11365
  In the activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL), NF-kB activity is essential for viability of the malignant cells and is... 
Proteins | Molecules | Rodents | T cell receptors | Lymphomas | Cytoplasm | Cells
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2014, Volume 111, Issue 6, p. 2349
  The clinical development of drug combinations is typically achieved through trial-and-error or via insight gained through a detailed molecular understanding... 
Drugs | Chemotherapy | Matrix | Lymphomas | Drug therapy | Cells
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 10/2019, Volume 9
Knockdown or gene disruption of the ubiquitously expressed cell surface receptor CD47 protects non-malignant cells from genotoxic stress caused by ionizing... 
Physiological aspects | Ionizing radiation | Chemotherapy | Cancer | schlafen-11 | CD47 | thrombospondin-1 | DNA damage response | radioresistance | epigenetics
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2017, Volume 60, Issue 12, pp. 4869 - 4881
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 10/2015, Volume 112, Issue 40, pp. 12480 - 12480
Adult T-cell leukemia (ATL) develops in individuals infected with human T-cell lymphotropic virus-1 (HTLV-1). Presently there is no curative therapy for ATL.... 
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 34, pp. 35247 - 35262
Journal Article