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1. Recent Advances in Lgr5^sup +^sup Stem Cell Research
by Carly Leung and Si Hui Tan and Nick Barker
Trends in Cell Biology, ISSN 0962-8924, 05/2018, Volume 28, Issue 5, p. 380
Research on the adult leucine-rich stem cell is presented. The authors review these recent advances and discuss their impact on efforts to harness the... 
Regeneration | Tissue engineering | Stem cells | Clinical trials | Metastasis | Clinical medicine | Leucine | Clinical outcomes | Cancer | Metastases
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2. Full Text Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition
by Murray, Christopher J L and Barber, Ryan M and Foreman, Kyle J and Ozgoren, Ayse Abbasoglu and Abd-Allah, Foad and Abera, Semaw F and Aboyans, Victor and Abraham, Jerry P and Abubakar, Ibrahim and Abu-Raddad, Laith J and Abu-Rmeileh, Niveen M and Achoki, Tom and Ackerman, Ilana N and Ademi, Zanfina and Adou, Arsène K and Adsuar, José C and Afshin, Ashkan and Agardh, Emilie E and Alam, Sayed Saidul and Alasfoor, Deena and Albittar, Mohammed I and Alegretti, Miguel A and Alemu, Zewdie A and Alfonso-Cristancho, Rafael and Alhabib, Samia and Ali, Raghib and Alla, François and Allebeck, Peter and Almazroa, Mohammad A and Alsharif, Ubai and Alvarez, Elena and Alvis-Guzman, Nelson and Amare, Azmeraw T and Ameh, Emmanuel A and Amini, Heresh and Ammar, Walid and Anderson, H Ross and Anderson, Benjamin O and Antonio, Carl Abelardo T and Anwari, Palwasha and Arnlöv, Johan and Arsenijevic, Valentina S Arsic and Artaman, Al and Asghar, Rana J and Assadi, Reza and Atkins, Lydia S and Avila, Marco A and Awuah, Baffour and Bachman, Victoria F and Badawi, Alaa and Bahit, Maria C and Balakrishnan, Kalpana and Banerjee, Amitava and Barker-Collo, Suzanne L and Barquera, Simon and Barregard, Lars and Barrero, Lope H and Basu, Arindam and Basu, Sanjay and Basulaiman, Mohammed O and Beardsley, Justin and Bedi, Neeraj and Beghi, Ettore and Bekele, Tolesa and Bell, Michelle L and Benjet, Corina and Bennett, Derrick A and Bensenor, Isabela M and Benzian, Habib and Bernabé, Eduardo and Bertozzi-Villa, Amelia and Beyene, Tariku J and Bhala, Neeraj and Bhalla, Ashish and Bhutta, Zulfiqar A and Bienhoff, Kelly and Bikbov, Boris and Biryukov, Stan and Blore, Jed D and Blosser, Christopher D and Blyth, Fiona M and Bohensky, Megan A and Bolliger, Ian W and Başara, Berrak Bora and Bornstein, Natan M and Bose, Dipan and Boufous, Soufiane and Bourne, Rupert R A and Boyers, Lindsay N and Brainin, Michael and Brayne, Carol E and Brazinova, Alexandra and Breitborde, Nicholas J K and Brenner, Hermann and Briggs, Adam D and Brooks, Peter M and Brown, Jonathan C and Brugha, Traolach S and Buchbinder, Rachelle and Buckle, Geoffrey C and ... and HALE Collaborator and GBD 2013 DALYs Collaborator and GBD 2013 DALYs and HALE Collaborators and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
The Lancet, ISSN 0140-6736, 11/2015, Volume 386, Issue 10009, pp. 2145 - 2191
Summary Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement... 
Internal Medicine | LOW SOCIOECONOMIC-STATUS | SYSTEMATIC ANALYSIS | RISK-FACTORS | CHANGING RELATION | EUROPEAN-UNION | ACUTE MYOCARDIAL-INFARCTION | MORTALITY TRENDS | NONCOMMUNICABLE DISEASES | ECONOMIC-DEVELOPMENT | SELF-RATED HEALTH | MEDICINE, GENERAL & INTERNAL | Quality-Adjusted Life Years | Communicable Diseases - epidemiology | Humans | Middle Aged | Chronic Disease - epidemiology | Male | Wounds and Injuries - epidemiology | Health Transition | Socioeconomic Factors | Mortality, Premature | Life Expectancy | Global Health - statistics & numerical data | Female | Aged | Health aspects | Epidemiology | Life expectancy | Studies | Disease | Mortality | Injuries | Age | Global Health | Communicable Diseases | Life Sciences | Wounds and Injuries | Santé publique et épidémiologie | Chronic Disease | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare | Nutrition and Disease | HNE Nutrition and Disease | Chair Nutrition and Disease | Voeding en Ziekte | VLAG | HNE Voeding en Ziekte
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3. Full Text Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
by Lingbeek, Merel and Shakhova, Olga and Liu, James and Leung, Carly and Marino, Silvia and Saremaslani, Parvin and Tanger, Ellen and van Lohuizen, Maarten
Nature, ISSN 0028-0836, 03/2004, Volume 428, Issue 6980, pp. 337 - 341
Overexpression of the polycomb group gene Bmi1 promotes cell proliferation and induces leukaemia through repression of Cdkn2a (also known as ink4a/Arf) tumour... 
TRANSFORMATION | STEM-CELLS | SONIC HEDGEHOG | MULTIDISCIPLINARY SCIENCES | BIOLOGY | N-MYC | C-MYC | PROLIFERATION | MICE | MUTATIONS | EXPRESSION | Oncogene Proteins - genetics | Humans | Repressor Proteins | Gene Expression Regulation, Neoplastic | Receptors, Cell Surface | Stem Cells - cytology | RNA, Messenger - metabolism | Stem Cells - metabolism | Cerebellum - embryology | Hedgehog Proteins | Gene Expression Regulation, Developmental | Cell Division | Gene Deletion | Membrane Proteins - metabolism | Patched Receptors | Medulloblastoma - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins - metabolism | Signal Transduction | Membrane Proteins - genetics | Cerebellum - metabolism | RNA, Messenger - genetics | Oncogene Proteins - metabolism | Intracellular Signaling Peptides and Proteins | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Medulloblastoma - metabolism | Transcription Factors - genetics | Mice, Knockout | Transcription Factors - metabolism | Phenotype | Animals | Polycomb Repressive Complex 1 | Cerebellum - cytology | Trans-Activators - metabolism | Mice | Zinc Finger Protein GLI1 | Patched-1 Receptor | Pathology | Cell culture | Gene expression | Leukemia | Tumors | Bmi1 gene | tumor suppressor genes | medulloblastoma | sonic hedgehog protein
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4. Full Text Recent Advances in Lgr5+ Stem Cell Research
by Leung, Carly and Tan, Si Hui and Barker, Nick
Trends in Cell Biology, ISSN 0962-8924, 05/2018, Volume 28, Issue 5, pp. 380 - 391
The discovery of leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5) as both a marker of adult stem cells and a critical modulator of their... 
COLON-CANCER | PROGENITOR CELLS | LIVER ZONATION | GASTRIC-CANCER | POSTNATAL MAMMARY-GLAND | COLORECTAL-CANCER | IN-VITRO EXPANSION | EPITHELIAL HOMEOSTASIS | LGR5-POSITIVE CELLS | SMALL-INTESTINE | CELL BIOLOGY | Adult Stem Cells | Cell Proliferation - genetics | Lung - pathology | Humans | Neoplastic Stem Cells | beta Catenin - genetics | Animals | Wnt Signaling Pathway - genetics | Regeneration - genetics | Lung - growth & development | Mice | Receptors, G-Protein-Coupled - genetics | Stem Cell Niche - genetics
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5. Full Text Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
by Seishima, Ryo and Leung, Carly and Yada, Swathi and Murad, Katzrin Bte Ahmed and Tan, Liang Thing and Hajamohideen, Amin and Tan, Si Hui and Itoh, Hideki and Murakami, Kazuhiro and Ishida, Yoshihiro and Nakamizo, Satoshi and Yoshikawa, Yusuke and Wong, Esther and Barker, Nick
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 17
Uterine gland development is essential for successful embryo implantation, decidua formation and placental development. Here the authors demonstrate that... 
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6. Full Text Dysregulation of cell adhesion and cell migration genes in Sox10 mutant neural crest
by Li, Zhining and Leung, Carly and Sit, Hon Man and Sham, Mai Har
Mechanisms of Development, ISSN 0925-4773, 07/2017, Volume 145, pp. S120 - S120
Genes
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7. Full Text Effectiveness of a binocular video game vs placebo video game for improving visual functions in older children, teenagers, and adults with amblyopia: A randomized clinical trial
by Gao, Tina Y and Guo, Cindy X and Babu, Raiju J and Black, Joanna M and Bobier, William R and Chakraborty, Arijit and Dai, Shuan and Hess, Robert F and Jenkins, Michelle and Jiang, Yannan and Kearns, Lisa S and Kowal, Lionel and Lam, Carly S. Y and Pang, Peter C. K and Parag, Varsha and Pieri, Roberto and Raveendren, Rajkumar Nallour and South, Jayshree and Staffieri, Sandra Elfride and Wadham, Angela and Walker, Natalie and Thompson, Benjamin and Clavagnier, Simon and Spiegel, Daniel and Ko, Ka Ching and Chu, Geoffrey and Chan, Lily and Leung, Mabel and Kwok, Yee Mui and Ding, Rifeng and Howe, Colin and Von Blaramberg, Taina and Michie, Joanna and Faatui, John Faafetai and Ng, Colleen and Uren, Stuart L and Boswell, Stephen J and BRAVO Study Team and for the BRAVO Study Team
JAMA Ophthalmology, ISSN 2168-6165, 02/2018, Volume 136, Issue 2, pp. 172 - 181
IMPORTANCE Binocular amblyopia treatment using contrast-rebalanced stimuli showed promise in laboratory studies and requires clinical trial investigation in a... 
DIABETIC-RETINOPATHY | PRESCHOOL-CHILDREN | CHILDHOOD AMBLYOPIA | TESTING PROTOCOL | VISION | INTEROCULAR SUPPRESSION | IPAD TREATMENT | OPHTHALMOLOGY | STEREOACUITY | TREATMENT INDEX | Clinical trials | Video games | Care and treatment | Usage | Analysis | Amblyopia | Online First | Original Investigation | Research
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8. Full Text Hiding from the moonlight: Luminosity and temperature affect activity of Asian nocturnal primates in a highly seasonal forest
by Starr, Carly and Nekaris, K.A.I and Leung, Luke
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, p. e36396
The effect of moonlight and temperature on activity of slow lorises was previously little known and this knowledge might be useful for understanding many... 
METABOLISM | BEHAVIOR | MULTIDISCIPLINARY SCIENCES | ACTIVITY PATTERNS | SLOW | CATHEMERAL ACTIVITY | DAILY TORPOR | MICROCEBUS-MURINUS | SOCIAL-ORGANIZATION | LORIS NYCTICEBUS-COUCANG | LEMUR | Trees | Darkness | Temperature | Animals | Moon | Light | Female | Male | Lorisidae - physiology | Seasons | Behavior, Animal - radiation effects | Protection and preservation | Primates | Snakes | Deciduous forests | Forests | Feeding behavior | Wildlife conservation | Bright tempering | Luminosity | Heat loss | Population studies | Males | Forest protection | Predators | Grooming | Animal behavior | Ambient temperature | Temperature effects | Females
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9. Full Text Examining patterns in medication documentation of trade and generic names in an academic family practice training centre
by Summers, Alexander and Ruderman, Carly and Leung, Fok-Han and Slater, Morgan
BMC Medical Education, ISSN 1472-6920, 09/2017, Volume 17, Issue 1, pp. 175 - 7
Background: Studies in the United States have shown that physicians commonly use brand names when documenting medications in an outpatient setting. However,... 
Generic medications | Hidden curriculum | Prescribing habits | Family medicine | Medication documentation | Residency | POTENTIAL SAVINGS | SUBSTITUTION | PHYSICIAN | BRAND-NAME | INDUSTRY | EDUCATION | RESIDENTS LEARN | EDUCATION & EDUCATIONAL RESEARCH | HIDDEN-CURRICULUM | DEFAULT OPTIONS | DRUG NAMES | EDUCATION, SCIENTIFIC DISCIPLINES | Drugs, Generic - classification | Medical Staff, Hospital | United States | Humans | Drugs, Generic - economics | Terminology as Topic | Documentation - statistics & numerical data | Practice Patterns, Physicians | Prescription Fees | Family Practice | Retrospective Studies | Electronic Health Records | Therapeutic Equivalency | Generic drugs | Dosage and administration | Management | Medical societies | Studies | Medical records | Curricula
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10. Full Text Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
by Naghavi, Mohsen and Wang, Haidong and Lozano, Rafael and Davis, Aian and Liang, Xiaofeng and Zhou, Maigeng and Vollset, Stein Emil and Ozgoren, Ayse Abbasoglu and Abdalla, Safa and Abd-Allah, Foad and Aziz, Muna I. Abdel and Abera, Semaw Ferede and Aboyans, Victor and Abraham, Biju and Abraham, Jerry P and Abuabara, Katrina E and Abubakar, Ibrahim and Abu-Raddad, Laith J and Abu-Rmeileh, Niveen M. E and Achoki, Tom and Adelekan, Ademola and Ademi, Zanfi Na and Adofo, Koranteng and Adou, Arsene Kouablan and Adsuar, Jose C and Aernlov, Johan and Agardh, Emilie Elisabet and Akena, Dickens and Al Khabouri, Mazin J and Alasfoor, Deena and Albittar, Mohammed and Alegretti, Miguel Angel and Aleman, Alicia V and Alemu, Zewdie Aderaw and Alfonso-Cristancho, Rafael and Alhabib, Samia and Ali, Mohammed K and Ali, Raghib and Alla, Francois and Al Lami, Faris and Allebeck, Peter and AlMazroa, Mohammad A and Salman, Rustam Al-Shahi and Alsharif, Ubai and Alvarez, Elena and Alviz-Guzman, Nelson and Amankwaa, Adansi A and Amare, Azmeraw T and Ameli, Omid and Hoek, Hans W and GBD Mortal 2013 Causes Death Colla and GBD 2013 Mortality and Causes of Death Collaborators and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
The Lancet, ISSN 0140-6736, 01/2015, Volume 385, Issue 9963, pp. 117 - 171
Summary Background Up-to-date evidence on levels and trends for age-sex-specific all-cause and cause-specific mortality is essential for the formation of... 
Internal Medicine | PNEUMOCOCCAL CONJUGATE VACCINE | CHILDHOOD PNEUMONIA | INFLUENZAE TYPE-B | RISK-FACTORS | PLACEBO-CONTROLLED-TRIAL | CHILDREN YOUNGER | POPULATION HEALTH | 187 COUNTRIES | INTEGRATED APPROACH | ENTERIC MULTICENTER | MEDICINE, GENERAL & INTERNAL | DOUBLE-BLIND | Databases, Factual - standards | Humans | Middle Aged | Child, Preschool | Infant | Male | Mortality - trends | Life Tables | Models, Statistical | Life Expectancy - trends | Young Adult | Global Health - trends | Adolescent | Global Health - statistics & numerical data | Aged, 80 and over | Sex Distribution | Adult | Cause of Death - trends | Female | Aged | Child | Child Mortality - trends | Infant, Newborn | Medicine, Experimental | Medical research | Analysis | Mortality | Global health | Disease | Malaria | Time series | Diarrhea | Epidemiology | Tuberculosis | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Meningitis | Trends | Injuries | Global Health | Cause of Death | Child Mortality | Life Sciences | Life Expectancy | Santé publique et épidémiologie | Databases, Factual | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare | Nutrition and Disease | HNE Nutrition and Disease | Chair Nutrition and Disease | Voeding en Ziekte | VLAG | HNE Voeding en Ziekte
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