X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (38) 38
human necessities (29) 29
hygiene (29) 29
medical or veterinary science (29) 29
preparations for medical, dental, or toilet purposes (29) 29
humans (27) 27
apoptosis (17) 17
specific therapeutic activity of chemical compounds ormedicinal preparations (17) 17
chemistry (16) 16
testing (16) 16
investigating or analysing materials by determining theirchemical or physical properties (15) 15
measuring (15) 15
metallurgy (15) 15
organic chemistry (15) 15
physics (15) 15
cancer (14) 14
cell line, tumor (14) 14
lung cancer, non-small cell (14) 14
pharmacology & pharmacy (14) 14
animals (12) 12
cell biology (12) 12
lung cancer (12) 12
proteins (12) 12
microbiology (11) 11
oncology (11) 11
phosphorylation (11) 11
beer (10) 10
biochemistry (10) 10
biochemistry & molecular biology (10) 10
compositions or test papers therefor (10) 10
condition-responsive control in microbiological orenzymological processes (10) 10
enzymology (10) 10
heterocyclic compounds (10) 10
measuring or testing processes involving enzymes, nucleicacids or microorganisms (10) 10
mutation or genetic engineering (10) 10
processes of preparing such compositions (10) 10
spirits (10) 10
vinegar (10) 10
wine (10) 10
apoptosis - drug effects (9) 9
care and treatment (9) 9
egfr (9) 9
female (9) 9
gefitinib (9) 9
genetic aspects (9) 9
growth (9) 9
male (9) 9
mutation (9) 9
pharmacology (9) 9
research (9) 9
signal transduction (9) 9
analysis (8) 8
antineoplastic agents - pharmacology (8) 8
carcinoma, non-small-cell lung - genetics (8) 8
epidermal growth factor (8) 8
mice (8) 8
mutations (8) 8
nsclc (8) 8
autophagy (7) 7
expression (7) 7
health aspects (7) 7
inhibitors (7) 7
lung neoplasms - genetics (7) 7
lung neoplasms - pathology (7) 7
quinazolines - pharmacology (7) 7
research paper (7) 7
respiratory tract diseases (7) 7
carcinoma, non-small-cell lung - pathology (6) 6
cells (6) 6
chemistry, organic (6) 6
gene expression (6) 6
identification (6) 6
inflammation (6) 6
kinases (6) 6
lung neoplasms - metabolism (6) 6
receptor, epidermal growth factor - metabolism (6) 6
tumors (6) 6
carcinoma, non-small-cell lung - drug therapy (5) 5
carcinoma, non-small-cell lung - metabolism (5) 5
cell cycle (5) 5
cell proliferation (5) 5
cell proliferation - drug effects (5) 5
development and progression (5) 5
discovery (5) 5
lung (5) 5
lung neoplasms - drug therapy (5) 5
medicine (5) 5
metabolism (5) 5
multidisciplinary sciences (5) 5
non-small cell lung cancer (5) 5
proliferation (5) 5
protein kinase inhibitors - pharmacology (5) 5
rheumatoid arthritis (5) 5
therapy (5) 5
aconitum carmichaelii (4) 4
activation (4) 4
arthritis (4) 4
article (4) 4
cell lines (4) 4
cell survival - drug effects (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
International Journal of Cancer, ISSN 0020-7136, 09/2019, Volume 145, Issue 5, pp. 1334 - 1345
Oncogenic KRAS is considered a promising target for anti‐cancer therapy. However, direct pharmacological strategies targeting KRAS‐driven cancers remained... 
TRANSPORT | ONCOLOGY | RAS ISOFORMS | GEFS | MUTATIONS | PROTEINS | GAPS | Target recognition | Lung cancer | Xenotransplantation | Pharmacology | K-Ras protein | Signal transduction | Signaling | Inhibitors | Xenografts | Docking | In vivo methods and tests | Disruption | Mutation | Protein transport | Localization | Transporter | Apoptosis
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 04/2017, Volume 58, Issue 16, pp. 1622 - 1626
is a widely used traditional Chinese medicine and important source of clinical drugs. The parent roots of were investigated resulting in the isolation and... 
8-Benzoyloxy group | Aconitum carmichaelii | 8-Butoxy group | C19-diterpenoid alkaloids | diterpenoid alkaloids
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 04/2017, Volume 58, Issue 16, p. 1622
Display Omitted 
Alkaloids | Medicine, Chinese
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 02/2018, Volume 28, Issue 5, pp. 339 - 357
Aims: Systemic diseases often have common characteristics. The aim of this study was to investigate the feasibility of targeting common pathological metabolism... 
Original Research Communications | lipogenesis | SREBP1 | rheumatoid arthritis | gefitinib-resistant NSCLC | ROS | berberine | RHEUMATOID-ARTHRITIS | CANCER-CELLS | APOPTOSIS | LOCALIZATION | ACTIVATED PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ATHEROSCLEROSIS | TRANSDUCTION | METABOLISM | LIPID RAFTS | ENDOCRINOLOGY & METABOLISM | Berberine - administration & dosage | Reactive Oxygen Species - metabolism | Humans | Synovial Fluid - metabolism | Synovial Fluid - drug effects | Arthritis, Rheumatoid - metabolism | Lipogenesis - genetics | Arthritis, Rheumatoid - drug therapy | Quinazolines - administration & dosage | Gefitinib | Carcinoma, Non-Small-Cell Lung - pathology | Oxidation-Reduction | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Fibroblasts - pathology | Arthritis, Rheumatoid - pathology | Gene Expression Regulation - drug effects | Arthritis, Rheumatoid - genetics | Drug Resistance, Neoplasm - genetics | Signal Transduction - drug effects | Sterol Regulatory Element Binding Protein 1 - genetics | Fibroblasts - drug effects | Quinazolines - adverse effects | Cell Line, Tumor | Cell Proliferation - drug effects | Carcinoma, Non-Small-Cell Lung - drug therapy | AMP-Activated Protein Kinases - genetics | Cell proliferation | Berberine | Oxygen | Lung cancer | Feasibility studies | Innovations | Rats | Arthritis | Metabolism | Palmitic acid | Diseases | Signal transduction | Signaling | Mitochondria | Rheumatoid arthritis | Rodents | Sterol regulatory element-binding protein | Xenografts | Fibroblasts | In vivo methods and tests | Inhibition | Lipogenesis | Cancer | Xenotransplantation | Proteins | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 12/2011, Volume 480, Issue Suppl. 7378, p. S100
  [...] this concept of personalized medicine has similarities with the individualized diagnostic and treatment methods of traditional Asian medicines... 
Medicine | Design | Genotype & phenotype | Biomedical research | Clinical trials | Pharmaceutical industry
Journal Article
Frontiers in pharmacology, ISSN 1663-9812, 2018, Volume 9, p. 728
Overexpression of epidermal growth factor receptor (EGFR) has been reported to be implicated in the pathogenesis of non-small cell lung cancer (NSCLC). Several... 
Journal Article
Frontiers of medicine, ISSN 2095-0217, 05/2019, pp. 1 - 8
Bromodomain PHD-finger transcription factor (BPTF) is the largest subunit of the nucleosome remodeling factor and plays an important role in chromatin... 
Thoracic surgery | Transcription factors | Laboratories | Lung cancer | Clinical trials | Breast cancer | Gene expression | Medicine | Cell growth | Medical prognosis | Cell cycle | DNA methylation | Epigenetics | Tumorigenesis | Deoxyribonucleic acid--DNA | Interferometry
Journal Article
by Pan, HD and Guo, RJ and Ju, YM and Wang, Q and Zhu, J and Xie, Y and Zheng, YF and Li, T and Liu, ZQ and Lu, LL and Li, F and Tong, B and Xiao, L and Xu, X and Leung, ELH and Li, RZ and Yang, HM and Wang, J and Zhou, H and Jia, HJ and Liu, L
MICROBIOME, ISSN 2049-2618, 07/2019, Volume 7, Issue 1, pp. 107 - 107
Background: Early treatment is key for optimizing the therapeutic success of drugs, and the current initiating treatment that blocks the progression of bone... 
SUPPLEMENTATION | IMMUNITY | MICROBIOLOGY | METABOLITES | MECHANISMS | INFLAMMATION | Antiarthritic agents | Rheumatoid factor | Oxidative stress | Usage | Research | Microbiota (Symbiotic organisms)
Journal Article
MedChemComm, ISSN 2040-2503, 2017, Volume 8, Issue 3, pp. 621 - 624
Mitoxantrone, an FDA-approved drug for multiple sclerosis and hormone refractory prostate cancer, is identified as a potent inhibitor of ROS1 fusion protein by... 
POTENT INHIBITOR | CHEMISTRY, MEDICINAL | OLD DRUGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRIZOTINIB | TARGETS | TRICKS | DISCOVERY
Journal Article
ISSN 1477-0520, 9/2018, Volume 16, Issue 35, pp. 6521 - 653
The selective modulation of individual bromodomains (BDs) by small molecules represents an important strategy for the treatment of various cancers, considering... 
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e14062 - e14062
Background: The cancer stem cell theory hypothesizes that cancers are perpetuated by cancer stem cells (CSC) or tumor initiating cells (TIC) possessing... 
COLON-CANCER | POPULATION | MARKER | MULTIDISCIPLINARY SCIENCES | GROWTH | HYALURONAN | PLURIPOTENCY | FLOW-CYTOMETRY | IDENTIFICATION | CD133(+) | TUMORS | Immunohistochemistry | Humans | Lung Neoplasms - metabolism | Middle Aged | Glycoproteins - metabolism | Peptides - genetics | Immunoblotting | Lung Neoplasms - pathology | Male | Transplantation, Heterologous | Gene Expression Profiling | Antigens, CD - genetics | Antigens, CD - metabolism | Neoplasms, Experimental - pathology | Octamer Transcription Factor-3 - genetics | Flow Cytometry | Peptides - metabolism | Neoplastic Stem Cells - metabolism | Hyaluronan Receptors - metabolism | Neoplasms, Experimental - genetics | Neoplastic Stem Cells - pathology | Female | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Glycoproteins - genetics | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | AC133 Antigen | Hyaluronan Receptors - genetics | Animals | Polycomb Repressive Complex 1 | Mice, Nude | Octamer Transcription Factor-3 - metabolism | Cell Line, Tumor | Aged | Mice | Neoplasms, Experimental - metabolism | Squamous cell carcinoma | Lung cancer, Non-small cell | Analysis | Stem cells | Flow cytometry | Biotechnology | Laboratories | Heart surgery | Oct-4 protein | Lung | Lung cancer | Colorectal cancer | Stem cell transplantation | Proteins | Allografts | Epidermal growth factor | CD44 antigen | Xenografts | Cell cycle | CD34 antigen | Subpopulations | Cell survival | Tumor cells | Markers | Non-small cell lung carcinoma | Tumor cell lines | Cisplatin | Studies | Polymerase chain reaction | Pathology | Cytometry | Properties (attributes) | Medical prognosis | Cell lines | In vivo methods and tests | Pluripotency | Tumors | Apoptosis | Cancer | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 1121 - 1121
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 8857 - 8857
RVX-208 is a recently reported inhibitor of bromo and extraterminal (BET) family proteins (including BRD2-4 and BRDT) with selectivity for the second... 
NETWORK ANALYSIS | LIGAND-BINDING | MULTIDISCIPLINARY SCIENCES | LYSINE ACETYLATION | TARGETING BROMODOMAINS | HISTONE RECOGNITION | FREE-ENERGY | CANCER | DISCOVERY | BET BROMODOMAINS | FAMILY | Proteins | Clinical trials | Antitumor activity | Free energy | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 03/2018, Volume 37, Issue 10, pp. 1354 - 1368
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.