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Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3387 - 3391
Addictive diseases, including addiction to heroin, prescription opioids, or cocaine, pose massive personal and public health costs. Addictions are chronic... 
STEADY-STATE METHADONE | FREELY MOVING RATS | MEDICINE, RESEARCH & EXPERIMENTAL | IN-VIVO MICRODIALYSIS | CORTICOTROPIN-RELEASING-FACTOR | MU-OPIOID-RECEPTOR | CHRONIC BINGE COCAINE | HPA-AXIS ACTIVATION | SINGLE-NUCLEOTIDE POLYMORPHISM | METHADONE-MAINTENANCE TREATMENT | MESSENGER-RNA LEVELS | Opioid-Related Disorders - drug therapy | Humans | Methadone - therapeutic use | Stress, Physiological | Cocaine-Related Disorders - genetics | Cocaine-Related Disorders - physiopathology | Neuropeptides - physiology | Receptors, Dopamine - drug effects | Receptors, Opioid - physiology | Dopamine - physiology | Opioid-Related Disorders - genetics | Dopaminergic Neurons - physiology | Limbic System - physiopathology | Hypothalamo-Hypophyseal System - physiopathology | Receptors, Dopamine - physiology | Limbic System - drug effects | Genetic Predisposition to Disease | Pharmacogenetics | Pituitary-Adrenal System - physiopathology | Basal Ganglia - physiopathology | Receptors, Opioid, mu - drug effects | Rats | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Cocaine-Related Disorders - drug therapy | Mice | Opioid-Related Disorders - physiopathology | Receptors, Opioid, mu - genetics | Reward | Receptors, Dopamine - genetics | Receptors, Opioid - drug effects | Basal Ganglia - drug effects | Receptors, Opioid, mu - physiology | Stress, Psychological - physiopathology | Messenger RNA | Opioids | Physiological aspects | Cocaine | Research | Health aspects | Sensory adaptation | Science in Medicine
Journal Article
Addiction Biology, ISSN 1355-6215, 07/2013, Volume 18, Issue 4, pp. 709 - 716
Journal Article
by Li, Y and Levran, O and Kim, J and Zhang, TJ and Chen, XD and Suo, C
SCIENTIFIC REPORTS, ISSN 2045-2322, 10/2019, Volume 9, Issue 1, pp. 1 - 9
It is extremely expensive to conduct large sample size array- or sequencing based genome scale association studies. For a quantitative trait, an extreme... 
EFFICIENCY | MULTIDISCIPLINARY SCIENCES | GENOME-WIDE ASSOCIATION | Quantitative trait loci | Data analysis | Phenotypes | Data processing | Genomes | Methadone | Sampling | Gene mapping | Genotypes
Journal Article
Psychopharmacology, ISSN 0033-3158, 8/2017, Volume 234, Issue 15, pp. 2259 - 2275
Non-medical use of prescription opioids such as the mu opioid receptor (MOP-r) agonist oxycodone is a growing problem in the USA and elsewhere. There is... 
RNA sequencing | Neurosciences | C57BL/6J mice | Biomedicine | Inflammation and immune-related genes | Pharmacology/Toxicology | Oxycodone self-administration | Psychiatry | SYSTEM | GLIAL ACTIVATION | PSYCHIATRY | RECEPTOR | PATTERNS | NEUROSCIENCES | NUCLEUS-ACCUMBENS | ADOLESCENT | HIPPOCAMPUS | PHARMACOLOGY & PHARMACY | CHEMOKINE | CCR5 | SEQ | Inflammation Mediators - immunology | Ventral Striatum - immunology | Dopamine | Age Factors | Gene Expression - drug effects | Oxycodone - administration & dosage | Mice, Inbred C57BL | Male | Inflammation - immunology | Ventral Striatum - metabolism | Sequence Analysis, RNA - methods | Ventral Striatum - drug effects | Inflammation - metabolism | Self Administration | Animals | Analgesics, Opioid - administration & dosage | Gene Expression - physiology | Inflammation Mediators - metabolism | Inflammation - genetics | Mice | Complications and side effects | Immune response | Oxycodone | Drug interactions | Genetic aspects | Corpus striatum | Gene expression | Health aspects | Methods | Brain | Self-administration | Drug abuse | Narcotics | Mesolimbic system | Genes | Opioid receptors (type mu) | Inflammation | Ribonucleic acid--RNA | Gene sequencing | Infusion | Alterations | Pathways | Rodents | Neostriatum | Dopamine receptors | Inflammation and immune related genes | C57BL | 6J mice
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0199951
Journal Article
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