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1. Full Text A comparison of automated segmentation and manual tracing for quantifying hippocampal and amygdala volumes
by Morey, Rajendra A and Petty, Christopher M and Xu, Yuan and Pannu Hayes, Jasmeet and Wagner, H. Ryan and Lewis, Darrell V and LaBar, Kevin S and Styner, Martin and McCarthy, Gregory
NeuroImage, ISSN 1053-8119, 04/2009, Volume 45, Issue 3, pp. 855 - 866
Large databases of high-resolution structural MR images are being assembled to quantitatively examine the relationships between brain anatomy, disease... 
POSTTRAUMATIC-STRESS-DISORDER | DEPRESSION | BRAIN SEGMENTATION | METAANALYSIS | MRI | ATROPHY | MESIAL TEMPORAL SCLEROSIS | SCHIZOPHRENIA | FREESURFER | NEUROSCIENCES | NEUROIMAGING | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Magnetic Resonance Imaging | Automation | Hippocampus - anatomy & histology | Amygdala - anatomy & histology | Image Processing, Computer-Assisted - methods | Humans | Computer science | Neurosciences | Universities and colleges | Comparative analysis | Mental illness | Studies | Brain | Medical research | Algorithms | Software | Boundaries
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2. Full Text Losing Neurons: Selective Vulnerability and Mesial Temporal Sclerosis
by Lewis, Darrell V
Epilepsia, ISSN 0013-9580, 10/2005, Volume 46, Issue 7, pp. 39 - 44
Mesial temporal sclerosis (MTS) is found in about two‐thirds of patients with refractory temporal lobe epilepsy (TLE), and surgical removal of the sclerotic... 
Genetic predisposition | Prolonged Febrile seizures | Mesial temporal sclerosis | Temporal Lobe epilepsy | Two‐hit hypothesis | Microdysgenesis | Initial precipitating injury | Two-hit hypothesis | temporal lobe epilepsy | HIPPOCAMPAL EXCITABILITY | two-hit hypothesis | ATROPHY | MRI | ABNORMALITIES | prolonged febrile seizures | CONVULSIONS | CLINICAL NEUROLOGY | MIGRATION DISORDERS | IMMATURE RAT MODEL | microdysgenesis | mesial temporal sclerosis | LOBE EPILEPSY | genetic predisposition | ANIMAL-MODEL | initial precipitating injury | Neurons - pathology | Temporal Lobe - abnormalities | Cell Count | Humans | Atrophy - pathology | Child, Preschool | Epilepsy, Temporal Lobe - physiopathology | Electroencephalography - statistics & numerical data | Seizures, Febrile - pathology | Gliosis - pathology | Seizures - physiopathology | Seizures, Febrile - physiopathology | Sclerosis - pathology | Epilepsy, Temporal Lobe - genetics | Seizures, Febrile - genetics | Limbic System - physiopathology | Female | Temporal Lobe - pathology | Epilepsy, Temporal Lobe - pathology | Disease Models, Animal | Genetic Predisposition to Disease | Rats | Hippocampus - pathology | Functional Laterality | Magnetic Resonance Imaging | Temporal Lobe - physiopathology | Animals | Hippocampus - abnormalities | Hippocampus - physiopathology
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3. Full Text Hippocampal sclerosis after febrile status epilepticus: The FEBSTAT study
by Lewis, Darrell V and Shinnar, Shlomo and Hesdorffer, Dale C and Bagiella, Emilia and Bello, Jacqueline A and Chan, Stephen and Xu, Yuan and MacFall, James and Gomes, William A and Moshé, Solomon L and Mathern, Gary W and Pellock, John M and Nordli, Douglas R and Frank, L. Matthew and Provenzale, James and Shinnar, Ruth C and Epstein, Leon G and Masur, David and Litherland, Claire and Sun, Shumei and FEBSTAT Study Team
Annals of Neurology, ISSN 0364-5134, 02/2014, Volume 75, Issue 2, pp. 178 - 185
Objective Whether febrile status epilepticus (FSE) produces hippocampal sclerosis (HS) and temporal lobe epilepsy (TLE) has long been debated. Our objective is... 
BIOMARKERS | SEIZURES | ABNORMALITIES | MRI | MAGNETIC-RESONANCE | EPILEPSY | NEUROSCIENCES | DAMAGE | CLINICAL NEUROLOGY | TEMPORAL-LOBE | CHILDREN | AGE | Prospective Studies | Follow-Up Studies | Sclerosis - etiology | Humans | Risk Factors | Status Epilepticus - pathology | Child, Preschool | Infant | Male | Hippocampus - pathology | Magnetic Resonance Imaging | Diffusion Magnetic Resonance Imaging | Status Epilepticus - complications | Female | Child | Convulsions & seizures | Epilepsy
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4. Full Text MRI abnormalities following febrile status epilepticus in children: The FEBSTAT study
by Shinnar, Shlomo and Bello, Jacqueline A and Chan, Stephen and Hesdorffer, Dale C and Lewis, Darrell V and MacFall, James and Pellock, John M and Nordli, Douglas R and Frank, L. Matthew and Moshe, Solomon L and Gomes, William and Shinnar, Ruth C and Sun, Shumei and FEBSTAT Study Team and For the FEBSTAT Study Team
Neurology, ISSN 0028-3878, 08/2012, Volume 79, Issue 9, pp. 871 - 877
Objective: The FEBSTAT study is a prospective study that seeks to determine the acute and long-term consequences of febrile status epilepticus (FSE) in... 
SEIZURES | TEMPORAL-LOBE EPILEPSY | HIPPOCAMPAL MALFORMATION | MAGNETIC-RESONANCE | SCLEROSIS | INJURY | MALROTATION | CONVULSIONS | CLINICAL NEUROLOGY | Prospective Studies | Humans | Risk Factors | Status Epilepticus - pathology | Child, Preschool | Infant | Male | Electroencephalography | Hippocampus - pathology | Seizures, Febrile - pathology | Magnetic Resonance Imaging | Neurologic Examination | Image Processing, Computer-Assisted | Diffusion Magnetic Resonance Imaging | Brain - pathology | Female | Temporal Lobe - pathology | Epilepsy, Temporal Lobe - pathology | Observer Variation | Cohort Studies | Age | 297 | 227 | 120
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5. Full Text Human herpesvirus 6 and 7 in febrile status epilepticus: The FEBSTAT study
by Epstein, Leon G and Shinnar, Shlomo and Hesdorffer, Dale C and Nordli, Douglas R and Hamidullah, Aaliyah and Benn, Emma K. T and Pellock, John M and Frank, L. Matthew and Lewis, Darrell V and Moshe, Solomon L and Shinnar, Ruth C and Sun, Shumei and FEBSTAT Study Team and FEBSTAT study team
Epilepsia, ISSN 0013-9580, 09/2012, Volume 53, Issue 9, pp. 1481 - 1488
Summary Purpose:  In a prospective study, Consequences of Prolonged Febrile Seizures in Childhood (FEBSTAT), we determined the frequency of human herpesvirus... 
Febrile seizures | Mesial temporal sclerosis | Human herpesvirus | Status epilepticus | POPULATION | TEMPORAL-LOBE EPILEPSY | CONVULSIVE STATUS EPILEPTICUS | VARIANT-B | IDENTIFICATION | CHILDHOOD | CLINICAL NEUROLOGY | CHILDREN | HUMAN-HERPESVIRUS-6 | SEIZURES | INFECTION | Seizures, Febrile - diagnosis | Prospective Studies | Humans | Child, Preschool | Roseolovirus Infections - diagnosis | Infant | Male | Status Epilepticus - diagnosis | Roseolovirus Infections - epidemiology | Seizures, Febrile - virology | Female | Status Epilepticus - epidemiology | Status Epilepticus - virology | Herpesvirus 7, Human - isolation & purification | Seizures, Febrile - epidemiology | Herpesvirus 6, Human - isolation & purification | Infant, Newborn | Antigen-antibody reactions | Viral antibodies | Medical colleges | Neurosciences | RNA | Comorbidity | DNA | Antibodies | Seizures (Medicine) | Biometry | Medical research | Epilepsy | Infections | Temporal lobe | Viremia | EEG | imaging | Fever | Infection | Polymerase chain reaction | Children | Age | Hippocampus | Injuries | Seizures | Mesial Temporal Sclerosis | Human Herpesvirus | Febrile Seizures | Status Epilepticus
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6. Full Text Plasma cytokines associated with febrile status epilepticus in children: A potential biomarker for acute hippocampal injury
by Gallentine, William B and Shinnar, Shlomo and Hesdorffer, Dale C and Epstein, Leon and Nordli, Douglas R and Lewis, Darrell V and Frank, L. Matthew and Seinfeld, Syndi and Shinnar, Ruth C and Cornett, Karen and Liu, Binyi and Moshé, Solomon L and Sun, Shumei and Bello, Jacqueline and Gomes, William and Hannigan, James and Katz, Sharyn and Mancini, Ann and Masur, David and Weiss, Erica and Chan, Stephen and Bonner, Melanie and MacFall, James and Provenzale, James and Song, Allen and Voyvodic, James and Xu, Yuan and Andy, Joanne and Conklin, Terrie and Grasso, Susan and Powers, Connie S and Kushner, David and Landers, Susan and Water, Virginia and Bush, Brian J and Davis, Lori L and Deng, Xiaoyan and Rogers, Christiane and Sabo, Cynthia Shier and Curran, John and Kim, Andrew and Rinaldi, Julie and Bagiella, Emilia and Brazemore, Tanya and Culbert, James and O'Hara, Kathryn and Snow, Jean and FEBSTAT Investigator Team
Epilepsia, ISSN 0013-9580, 06/2017, Volume 58, Issue 6, pp. 1102 - 1111
Summary Objective Our aim was to explore the association between plasma cytokines and febrile status epilepticus (FSE) in children, as well as their potential... 
Mesial temporal lobe epilepsy | Interleukin | Hippocampal injury | Cytokine | Febrile status epilepticus | INTERLEUKIN-1-BETA LEVELS | MECHANISMS | CEREBROSPINAL-FLUID | CLINICAL NEUROLOGY | FACTOR-ALPHA | IL-1 RECEPTOR ANTAGONIST | SEIZURES | PHENOMENOLOGY | EPIDERMAL-GROWTH-FACTOR | EPILEPSY | INFLAMMATORY CYTOKINES | Brain Damage, Chronic - blood | Humans | Risk Factors | Seizures, Febrile - blood | Child, Preschool | Infant | Male | Status Epilepticus - diagnostic imaging | Biomarkers - blood | Hippocampus - diagnostic imaging | Interleukin 1 Receptor Antagonist Protein - blood | Interleukin-1beta - blood | Seizures, Febrile - diagnostic imaging | Epilepsy, Temporal Lobe - blood | Interleukin-6 - blood | Female | Brain Damage, Chronic - diagnostic imaging | Interleukin-8 - blood | Child | Hippocampus - physiopathology | Infant, Newborn | Cytokines - blood | Status Epilepticus - blood | Yuan (China) | Epidermal growth factor | Seizures (Medicine) | Children | Interleukins | Status epilepticus | Temporal lobe | Nuclear magnetic resonance--NMR | Cytokines | Interleukin 1 receptor antagonist | Epilepsy | Inflammation | Interleukin 1 receptors | Fever | Interleukin 6 | Convulsions & seizures | Magnetic resonance imaging | Interleukin 1 | Biomarkers | Hippocampus | Interleukin 8 | Seizures | cytokine | hippocampal injury | interleukin | febrile status epilepticus | mesial temporal lobe epilepsy
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7. Religion & globalization
: world religions in historical perspective
by Esposito, John L and Fasching, Darrell J., 1944 and Lewis, Todd V., 1949
2008, ISBN 9780195176957, viii, 609
Religious aspects | Globalization | Religions
Book
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8. Full Text Disruption of Fgf13 causes synaptic excitatory–inhibitory imbalance and genetic epilepsy and febrile seizures plus
by Puranam, Ram S and He, Xiao Ping and Yao, Lijun and Le, Tri and Jang, Wonjo and Rehder, Catherine W and Lewis, Darrell V and McNamara, James O
Journal of Neuroscience, ISSN 0270-6474, 2015, Volume 35, Issue 23, pp. 8866 - 8881
We identified a family in which a translocation between chromosomes X and 14 was associated with cognitive impairment and a complex genetic disorder termed... 
Translocation | Animal model | Excitatory inhibitory imbalance | GEFS | Fgf13 | Epilepsy | epilepsy | excitatory inhibitory imbalance | LOCALIZATION | GEFS(+) | translocation | FACTOR HOMOLOGOUS FACTORS | GAMMA-2-SUBUNIT | SODIUM-CHANNEL | EPILEPTOGENESIS | NEUROSCIENCES | INACTIVATION | MOUSE MODEL | MUTATION | animal model | GENERALIZED EPILEPSY | MODULATION | Age Factors | Embryo, Mammalian | Fever - complications | Humans | Middle Aged | NAV1.1 Voltage-Gated Sodium Channel - genetics | Fibroblast Growth Factors - genetics | Family Health | Male | NAV1.1 Voltage-Gated Sodium Channel - metabolism | Synapses - genetics | Epilepsy - physiopathology | Young Adult | Cognition Disorders - etiology | Seizures, Febrile - genetics | Neurons - physiology | Epilepsy - genetics | Female | X Chromosome - genetics | Disease Models, Animal | Animals, Newborn | Cell Line | Synaptic Potentials - genetics | Mice, Transgenic | Cognition Disorders - genetics | Hippocampus - pathology | Seizures, Febrile - etiology | Mutation - genetics | Nerve Tissue Proteins - metabolism | Animals | Sex Factors | Mice | Epilepsy - pathology | Translocation, Genetic - genetics
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9. Full Text Design and phenomenology of the FEBSTAT study
by Hesdorffer, Dale C and Shinnar, Shlomo and Lewis, Darrell V and Moshé, Solomon L and Nordli, Douglas R and Pellock, John M and MacFall, James and Shinnar, Ruth C and Masur, David and Frank, L. Matthew and Epstein, Leon G and Litherland, Claire and Seinfeld, Syndi and Bello, Jacqueline A and Chan, Stephen and Bagiella, Emilia and Sun, Shumei and FEBSTAT Study Team and FEBSTAT study team
Epilepsia, ISSN 0013-9580, 09/2012, Volume 53, Issue 9, pp. 1471 - 1480
Summary Purpose:  Febrile status epilepticus (FSE) has been associated with hippocampal injury and subsequent hippocampal sclerosis (HS) and temporal lobe... 
Febrile seizures | Children | Status epilepticus | Epidemiology | PROLONGED FEBRILE SEIZURES | TEMPORAL-LOBE EPILEPSY | MRI | ABNORMALITIES | ATROPHY | SCLEROSIS | CONVULSIONS | CLINICAL NEUROLOGY | MESIAL STRUCTURES | MAGNETIC-RESONANCE | Seizures, Febrile - diagnosis | Prospective Studies | Humans | Child, Preschool | Infant | Male | Pilot Projects | Seizures, Febrile - therapy | Female | Seizures, Febrile - epidemiology | Child | Research Design | Infant, Newborn | Cohort Studies | Parenting | Medical colleges | Neurosciences | Epilepsy | Electroencephalography | Seizures (Medicine) | Biomedical engineering | Phenomenology | Convulsions & seizures | Nuclear magnetic resonance--NMR | Age | Children & youth | Temporal lobe | Vocalization behavior | Complications | EEG | Sclerosis | Hospitals | Magnetic resonance imaging | Development | Hippocampus | Injuries | Seizures | Febrile Seizures | Status Epilepticus
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10. Full Text Hippocampal MRI Signal Hyperintensity After Febrile Status Epilepticus Is Predictive of Subsequent Mesial Temporal Sclerosis
by Provenzale, James M and Barboriak, Daniel P and VanLandingham, Kevan and MacFall, James and Delong, David and Lewis, Darrell V
American Journal of Roentgenology, ISSN 0361-803X, 04/2008, Volume 190, Issue 4, pp. 976 - 983
OBJECTIVE. The objective of our study was to test the hypothesis that the finding of hyperintense hippocampal signal intensity on T2-weighted MR images soon... 
CNS | Mesial temporal sclerosis | Pediatric imaging | MRI | Epilepsy | Hippocampus | epilepsy | hippocampus | ABNORMALITIES | FAST SPIN-ECHO | APPARENT DIFFUSION-COEFFICIENT | KAINIC ACID | RESONANCE-IMAGING EVIDENCE | pediatric imaging | NO ASSOCIATION | SEIZURES | mesial temporal sclerosis | LOBE EPILEPSY | TERM-FOLLOW-UP | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | BRAIN | Prospective Studies | Sclerosis - etiology | Humans | Status Epilepticus - pathology | Child, Preschool | Magnetic Resonance Imaging - methods | Infant | Linear Models | Male | Epilepsy, Temporal Lobe - etiology | Hippocampus - pathology | Seizures, Febrile - pathology | Sclerosis - pathology | Status Epilepticus - complications | Female | Child | Epilepsy, Temporal Lobe - pathology | Seizures, Febrile - complications
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11. Full Text Acute EEG findings in children with febrile status epilepticus: Results of the FEBSTAT study
by Nordli, Douglas R and Moshé, Solomon L and Shinnar, Shlomo and Hesdorffer, Dale C and Sogawa, Yoshimi and Pellock, John M and Lewis, Darrell V and Frank, L. Matthew and Shinnar, Ruth C and Sun, Shumei and FEBSTAT Study Team and For the FEBSTAT Study Team
Neurology, ISSN 0028-3878, 11/2012, Volume 79, Issue 22, pp. 2180 - 2186
Objective: The FEBSTAT (Consequences of Prolonged Febrile Seizures) study is prospectively addressing the relationships among serial EEG, MRI, and clinical... 
BIOMARKERS | SEIZURES | TEMPORAL-LOBE EPILEPSY | SCLEROSIS | CONVULSIONS | EPILEPTOGENESIS | CLINICAL NEUROLOGY | Seizures, Febrile - diagnosis | Acute Disease | Humans | Status Epilepticus - pathology | Child, Preschool | Infant | Male | Electroencephalography - methods | Seizures, Febrile - pathology | Status Epilepticus - diagnosis | Seizures, Febrile - physiopathology | Status Epilepticus - physiopathology | Female | Infant, Newborn | 227
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12. Disruption of Fgf13 Causes Synaptic Excitatory-Inhibitory Imbalance and Genetic Epilepsy and Febrile Seizures Plus
by Puranam, Ram S and He, Xiao Ping and Yao, Lijun and Le, Tri and Jang, Wonjo and Rehder, Catherine W and Lewis, Darrell V and McNamara, James O
Journal of Neuroscience, ISSN 0270-6474, 06/2015, Volume 35, Issue 23, pp. 8866 - 8881
We identified a family in which a translocation between chromosomes X and 14 was associated with cognitive impairment and a complex genetic disorder termed... 
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13. Full Text Facilitation of the Induction of Long-Term Potentiation by GABA$_B$ Receptors
by David D. Mott and Darrell V. Lewis
Science, ISSN 0036-8075, 6/1991, Volume 252, Issue 5013, pp. 1718 - 1720
Long-term potentiation (LTP), an in vitro model of learning, was induced in hippocampal slices by 5-hertz stimulation. During induction, γ-aminobutyric acid A... 
Depolarization | Receptors | Neuroscience | Dentate gyrus | N methyl D aspartate receptors | Long term potentiation | GABA antagonists | Reports | Theta rhythm | Membrane potential | T tests | RAT DENTATE GYRUS | DEPRESSION | RESPONSES | BACLOFEN | INHIBITION | STIMULATION | 2-HYDROXY-SACLOFEN | INVITRO | MULTIDISCIPLINARY SCIENCES | ANTAGONISTS | HIPPOCAMPAL-NEURONS
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14. Full Text Risk factors for subsequent febrile seizures in the FEBSTAT study
by Hesdorffer, Dale C and Shinnar, Shlomo and Lax, Daniel N and Pellock, John M and Nordli, Douglas R and Seinfeld, Syndi and Gallentine, William and Frank, L. Matthew and Lewis, Darrell V and Shinnar, Ruth C and Bello, Jacqueline A and Chan, Stephen and Epstein, Leon G and Moshé, Solomon L and Liu, Binyi and Sun, Shumei and Berman, Evelyn and Gomes, William and Hannigan, James and Katz, Sharyn and Mancini, Ann and Masur, David and Sogawa, Yoshimi and Weiss, Erica and Bonner, Melanie and Cornett, Karen and MacFall, James and Provenzale, James and Song, Allen and Voyvodic, James and Xu, Yuan and Andy, Joanne and Conklin, Terrie and Grasso, Susan and Powers, Connie S and Kushner, David and Landers, Susan and Van de Water, Virginia and Bush, Brian J and Davis, Lori L and Deng, Xiaoyan and Rogers, Christiane and Sabo, Cynthia Shier and Curran, John and Kim, Andrew and Miazga, Diana and Rinaldi, Julie and Bagiella, Emilia and Brazemore, Tanya and Culbert, James and O'Hara, Kathryn and Snow, Jean and FEBSTAT Study Team and FEBSTAT study team and the FEBSTAT study team
Epilepsia, ISSN 0013-9580, 07/2016, Volume 57, Issue 7, pp. 1042 - 1047
Summary Objectives To identify risk and risk factors for developing a subsequent febrile seizure (FS) in children with a first febrile status epilepticus (FSE)... 
Febrile seizure recurrence | Status epilepticus | Simple febrile seizure | PHENOMENOLOGY | RECURRENCE | CONVULSIONS | CLINICAL NEUROLOGY | CHILDREN | Seizures, Febrile - diagnosis | Humans | Risk Factors | Proportional Hazards Models | Child, Preschool | Infant | Male | Electroencephalography | Seizures, Febrile - etiology | Status Epilepticus - diagnosis | Magnetic Resonance Imaging | Regression Analysis | Status Epilepticus - complications | Female | Status Epilepticus - epidemiology | Seizures, Febrile - epidemiology | Cohort Studies | Yuan (China) | Medical research | Epilepsy | Medicine, Experimental | Febrile convulsions | Risk factors | Antianxiety agents | Health risk assessment | Convulsions & seizures | Nuclear magnetic resonance--NMR | Febrile Seizure recurrence | Status Epilepticus
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