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Cell Research, ISSN 1001-0602, 2011, Volume 21, Issue 1, pp. 131 - 145
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 08/2013, Volume 13, Issue 9, pp. 679 - 692
Journal Article
Journal Article
The Biochemical journal, ISSN 0264-6021, 2014, Volume 463, Issue 1, pp. 2 - e2
IKKβ (IκB kinase β) is a core component of signalling pathways that control the activation of NF-κB (nuclear factor κB) transcription factors, which regulate... 
MAP Kinase Kinase Kinases - metabolism | Protein Processing, Post-Translational | Animals | I-kappa B Kinase - metabolism | Humans
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 08/2017, Volume 474, Issue 16, pp. 2897 - 2899
Journal Article
Angewandte Chemie, ISSN 1433-7851, 09/2012, Volume 51, Issue 37, p. 9366
  Going for the hat-trick: The synthesis of the entire callipeltoside family of natural products is described. Key to this synthesis was the coupling of the... 
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2004, Volume 382, Issue 2, pp. 393 - 409
Two members of the NF-kappaB (nuclear factor kappaB)/Rel transcription factor family, NF-kappaB1 and NF-kappaB2, are produced as precursor proteins, NF-kappaB1... 
IκB kinase (IKK) | p100 | Tumour progression locus-2 (TPL-2) | Nuclear factor κB (NF-κB) | p105 | Toll-like receptor (TLR) | nuclear factor kappa B (NF-kappa B) | TRCP UBIQUITIN LIGASE | I kappa B kinase (IKK) | BIOCHEMISTRY & MOLECULAR BIOLOGY | P105 REQUIRES PHOSPHORYLATION | ALLERGIC AIRWAY INFLAMMATION | KINASE KINASE KINASE | P50 SUBUNIT | GLYCINE-RICH REGION | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | tumour progression locus-2 (TPL-2) | NF-KAPPA-B | SIGNAL-TRANSDUCTION PATHWAY | TNF, tumour necrosis factor | GC, germinal centre | NEMO, nuclear factor κB essential modulator | MAP 3-kinase, MAP kinase kinase kinase | BAFF, B-cell activating factor | ERK, extracellular-signal-regulated kinase | Fn14, fibroblast-growth-factor-inducible 14 | ABIN, A20-binding inhibitor of nuclear factor κB | GM-CSF, granulocyte–macrophage colony-stimulating factor | GSK, glycogen synthase kinase | Dif, Dorsal-related immunity factor | EBNA1, EBV nuclear antigen 1 | BMDM, bone-marrow-derived macrophage | NF-κB, nuclear factor κB | SCF, Skp1 | Imd, immune deficiency | F-box | IL, interleukin | MAP kinase, mitogen-activated protein kinase | EBV, Epstein–Barr virus | LPS, lipopolysaccharide | IFNβ, interferon-β | IκB, inhibitor of nuclear factor κB | TRAF, TNF-receptor-associated factor | TLR, Toll-like receptor | DC, dendritic cell | IKK, IκB kinase | GRR, glycine-rich region | Review | JNK, c-Jun N-terminal kinase | PGRP-LC, peptidoglycan recognition protein LC | ERK kinase | RANKL, receptor activator of NF-κB ligand | LTβR, lymphotoxin-β receptor | MIP, macrophage inflammatory protein | DD, death domain | HTLV-1, human T-cell leukaemia virus type 1 | MEK, MAP kinase | COX-2, cyclo-oxygenase-2 | TH2, T-helper 2 | TH1, T-helper 1 | LMP1, latent membrane protein 1 | TPL-2, tumour progression locus-2 | TWEAK, TNF-like weak inducer of apoptosis | Cul1 | PEST region, polypeptide sequence enriched in proline (P), glutamic acid (E), serine (S) and threonine (T) | RHD, Rel homology domain | nuclear factor κB (NF-κB) | NIK, NF-κB-inducing kinase | MEF, mouse embryo fibroblast | βTrCP, β-transducin repeat-containing protein
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2016, Volume 12, Issue 8
Persistent TH2 cytokine responses following chronic helminth infections can often lead to the development of tissue pathology and fibrotic scarring. Despite a... 
Medical research | Mortality | Lipids | Infections | Inflammation | Kinases | Metabolism | Gene expression | Experiments | Morbidity | Pathology | Rodents | Bone marrow
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2014, Volume 111, Issue 9, p. E846
  Interleukin (IL)-7 is critical for the maintenance of the peripheral T-cell compartment of the adaptive immune system. IL-7 receptor α ( IL-7Rα) expression... 
Cytokines | Homeostasis | Cell division | T cell receptors | Immune system
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2014, Volume 111, Issue 9, pp. 3212 - 3212
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 03/2014, Volume 111, Issue 9, pp. E846 - E846
Interleukin (IL)-7 is critical for the maintenance of the peripheral T-cell compartment of the adaptive immune system. IL-7 receptor alpha ( IL-7R alpha )... 
Journal Article
Trends in Immunology, ISSN 1471-4906, 2008, Volume 29, Issue 10, pp. 469 - 478
NF-κB (nuclear factor-κB) transcription factors have multiple critical roles in the regulation of immune responses. In unstimulated cells, NF-κB proteins are... 
Allergy and Immunology | LYS63-LINKED POLYUBIQUITINATION | IMMUNE-RESPONSE | SIGNALING PATHWAYS | UBIQUITIN-CONJUGATING ENZYME | ALPHA-DEPENDENT APOPTOSIS | GENE-EXPRESSION | IKK-ALPHA | TNF-ALPHA | IMMUNOLOGY | DEUBIQUITINATING ENZYME CYLD | CUTTING EDGE
Journal Article
Immunological Reviews, ISSN 0105-2896, 03/2012, Volume 246, p. 168
Nuclear factor-[kappa]B (NF-[kappa]B) and mitogen-activated protein kinase (MAPK) activation play central roles in the induction of gene expression in innate... 
Care and treatment | Gene expression | Protein kinases | Cancer | Protein binding
Journal Article
Immunological Reviews, ISSN 0105-2896, 03/2012, Volume 246, Issue 1, pp. 168 - 182
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2014, Volume 111, Issue 23, p. E2394
  The MEK-1/2 kinase TPL-2 is critical for Toll-like receptor activation of the ERK-1/2 MAP kinase pathway during inflammatory responses, but it can transform... 
Phosphorylation | Cellular biology | Oncology | Kinases | Cells
Journal Article
Immunological Reviews, ISSN 0105-2896, 03/2012, Volume 246, Issue 1, pp. 168 - 182
Journal Article