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Tetrahedron, ISSN 0040-4020, 06/2018, Volume 74, Issue 25, pp. 3086 - 3086
Journal Article
ISSN 0040-4020, 2018
Professor Steven Ley is currently Professor of Chemistry and Director of Research at at the University of Cambridge. He is also a Fellow of Trinity College and... 
Journal Article
1989, Reactivity and structure : concepts in organic chemistry, ISBN 9783540510239, Volume 27., x, 133
Book
Tetrahedron, ISSN 0040-4020, 06/2018, Volume 74, Issue 25, pp. 3085 - 3085
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 05/2018, Volume 57, Issue 19, pp. 5182 - 5183
“Chemical synthesis has previously tended to rely heavily on robust labour‐intensive processes. We have been advocating a machine‐assisted approach to... 
CHEMISTRY, MULTIDISCIPLINARY | Software | Chemical Engineering | Equipment Design | Machine Learning | Humans | Chemical synthesis
Journal Article
Chemical Science, ISSN 2041-6520, 02/2015, Volume 6, Issue 2, pp. 1120 - 1125
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 01/2020, Volume 26, Issue 1, pp. 186 - 191
A practically useful coupling reaction between aromatic halides and redox‐active esters was realized by nickel catalysis through the use of a packed zinc bed... 
cross-coupling | continuous flow | nickel | packed-column | redox-active ester
Journal Article
The Chemical Record, ISSN 1527-8999, 08/2012, Volume 12, Issue 4, pp. 378 - 390
The principles of Green Chemistry are important but challenging drivers for most modern synthesis programs. To meet these challenges new flow chemistry tools... 
natural products | green chemistry | synthetic methods | flow chemistry | scale‐up | scale-up | SOLID-SUPPORTED REAGENTS | 3-STEP SYNTHESIS | AMARYLLIDACEAE ALKALOID (+)-PLICAMINE | SCAVENGERS | CHEMISTRY, MULTIDISCIPLINARY | POTENT | MULTISTEP ORGANIC-SYNTHESIS | SEQUENCE | ENABLING TECHNOLOGY | BATCH | CONCISE SYNTHESIS | Green chemistry | Green technology
Journal Article
ISSN 1477-0520, 9/2018, Volume 16, Issue 36, pp. 6652 - 6654
A three-component synthesis of homoallylic amines is described. The allylboronic species were generated in situ by homologation of vinyl boroxines with... 
Journal Article
Chemical Communications, ISSN 1359-7345, 08/2014, Volume 50, Issue 64, pp. 8908 - 8911
The first regioselective ortho-lithiation at the 4-position of simple pyridine derivatives containing a 3-oxetane unit has been achieved using n-butyllithium... 
FUNCTIONALIZATION | DESIGN | ASYMMETRIC-SYNTHESIS | DIRECTED ORTHO-METALATION | DRUG DISCOVERY | POLYMERIZATION | LITHIUM | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | STRATEGIES | Pyridines | Derivatives | Bearing | Quenching
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 01/2018, Volume 16, Issue 36, pp. 6652 - 6654
A three-component synthesis of homoallylic amines is described. The allylboronic species were generated in situ by homologation of vinyl boroxines with... 
Amines | Imines | Information processing | Homology | Aliphatic compounds | Functional groups
Journal Article
Tetrahedron, ISSN 0040-4020, 04/2017, Volume 73, Issue 14, p. 1812
Flow chemistry enables the preparation of bis(indolyl)methanes from various indoles and structurally divergent aldehydes using Sc(OTf).sub.3 catalysis. The... 
Methane | Catalysis
Journal Article
Angewandte Chemie, ISSN 0044-8249, 05/2018, Volume 130, Issue 19, pp. 5278 - 5279
Die chemische Synthese ist zum heutigen Stand noch auf arbeitsintensive Prozesse angewiesen. Wir postulieren nun schon seit einigen Jahren eine maschinell... 
Journal Article
Angewandte Chemie, ISSN 1433-7851, 01/2015, Volume 54, Issue 4, pp. 1284 - 1288
  PlantazolicinA, a linear decacyclic natural product, exhibits desirable selective activity against the causative agent of anthrax toxicity. The total... 
Natural products | Synthesis | Precursors | Anthrax | Toxicity | Oxazole | Amino acids
Journal Article
Angewandte Chemie, ISSN 0044-8249, 05/2018, Volume 130, Issue 19, pp. 5278 - 5279
Die chemische Synthese ist zum heutigen Stand noch auf arbeitsintensive Prozesse angewiesen. Wir postulieren nun schon seit einigen Jahren eine maschinell... 
Organic chemistry
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 8, pp. 2264 - 2271
In fragment-based drug discovery (FBDD), a weakly binding fragment hit is elaborated into a potent ligand by bespoke functionalization along specific... 
Amines | Workflow | Mapping | Substrates | Continuous flow | Fragmentation | Proteins | Synthesis | Transformations (mathematics) | Dehydrogenation | Experimentation | Coupling | Laboratory apparatus | Functional groups
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 02/2015, Volume 48, Issue 2, p. 349
Journal Article
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