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chemistry (23) 23
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1. Full Text EMS1 and BRI1 control separate biological processes via extracellular domain diversity and intracellular domain conservation
by Zheng, BW and Bai, QW and Wu, L and Liu, H and Liu, YP and Xu, WJ and Li, GS and Ren, HY and She, XP and Wu, G
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 4165 - 10
In flowering plants, EMS1 (Excess Microsporocytes 1) perceives TPD1 (Tapetum Determinant 1) to specify tapeta, the last somatic cell layer nurturing pollen... 
BRASSINOSTEROIDS | REGULATOR | GENOME REVEALS | EVOLUTION | ANTHER | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | RECEPTOR-LIKE KINASES | GENE-EXPRESSION | ARABIDOPSIS | CELL FATE | Plants (botany) | Phenotypes | Biological evolution | Intracellular signalling | Dephosphorylation | Kinases | Biodiversity | Biological activity | Domains | Signaling | Signal transduction | Flowering | Pollen | Intracellular
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2. Full Text Values of biomarkers in the diagnosis of Coronary heart disease
by Qiushang, Ji and Miao, Li and Yun, Zhang and Xuping, Wang and Rong, Wang and Guishuang, Li and Yuguo, Chen
Heart, ISSN 1355-6037, 10/2011, Volume 97, Issue Suppl 3, pp. A138 - A138
Objective To clarify the value of plasma levels of high sensitivity C reactive protein (hs-CRP), soluble CD40 ligand (sCD40L), monocyte chemoattractant... 
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3. Full Text Predicting suitable cultivation regions of medicinal plants with Maxent modeling and fuzzy logics: a case study of Scutellaria baicalensis in China
by Zhang, Linlin and Cao, Bo and Bai, Chengke and Li, Guishuang and Mao, Mingce
Environmental Earth Sciences, ISSN 1866-6280, 3/2016, Volume 75, Issue 5, pp. 1 - 12
Scientific prediction of suitable cultivation regions is an effective way for the assessment of habitat suitability and resource conservation to protect... 
Habitat distribution | Earth Sciences | Hydrology/Water Resources | Biogeosciences | Scutellaria baicalensis Georgi | Geology | Geochemistry | Fuzzy logics | Environmental factor | Terrestrial Pollution | Maxent modeling | GIS | Environmental Science and Engineering | ENVIRONMENTAL SCIENCES | GEOSCIENCES, MULTIDISCIPLINARY | ABIOTIC STRESS | NICHE | SPECIES DISTRIBUTIONS | WATER RESOURCES | Medicinal plants | Case studies | Models | Medicine, Herbal | Analysis | Medicine, Botanic | Fuzzy logic | Flowers & plants | Habitats | Geographic information systems | Environmental conditions
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4. Full Text Anterior Cervical Discectomy and Fusion Versus Hybrid Decompression and Fusion for the Treatment of 3-Level Cervical Spondylotic Myelopathy: A Comparative Analysis of Cervical Sagittal Balance and Outcomes
by Xu, Zhengquan and Xu, Zixing and Xu, Weihong and Rao, Hongming and Zhang, Liqun and Li, Guishuang
World Neurosurgery, ISSN 1878-8750, 12/2019, Volume 132, pp. e752 - e758
To compare the cervical sagittal balance and surgical outcomes between anterior cervical discectomy and fusion (ACDF) and hybrid decompression and fusion (HDF;... 
Anterior cervical discectomy and fusion | Cervical spondylotic myelopathy | Outcomes | Hybrid decompression and fusion | Sagittal balance
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5. Full Text Transcriptomic analysis and dynamic expression of genes reveal flavonoid synthesis in Scutellaria viscidula
by Bai, Chengke and Xu, Jun and Cao, Bo and Li, Xia and Li, Guishuang
Acta Physiologiae Plantarum, ISSN 0137-5881, 9/2018, Volume 40, Issue 9, pp. 1 - 11
Scutellaria viscidula Bunge (Labiatae), a perennial herb, is an important medicinal plant that possesses broad pharmacological actions. S. viscidula contains... 
Plant Anatomy/Development | Plant Genetics and Genomics | Transcriptome | Plant Physiology | Gene expression | Flavonoid | Medicinal plant | Life Sciences | Plant Pathology | Plant Biochemistry | Agriculture | Unigene | Scutellaria viscidula | ARABIDOPSIS-THALIANA | TTG1 | PLANT SCIENCES | RESPONSES | PROANTHOCYANIDIN | METABOLISM | PATHWAY | BIOSYNTHESIS | TT8 | MAIZE | BHLH | Flavonoids | Flavones | Bioflavonoids | Scullcap | Genetic aspects | Models | Biosynthesis | Properties
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6. Full Text Conbercept for Treatment of Neovascular Age-related Macular Degeneration: Results of the Randomized Phase 3 PHOENIX Study
by Liu, Kun and Liu, Xiaoling and Song, Yanping and Xu, Gezhi and Xu, Xun and Ye, Jian and Wu, Quan and Wu, Zhifeng and Dong, Xiaoguang and Zhang, Mingzhi and Xing, Yiqiao and Zhu, Shaoping and Chen, Xia and Shen, Yinchen and Huang, Hengye and Yu, Liyun and Ke, Zunhong and Rosenfeld, Philip J and Kaiser, Peter K and Ying, Guishuang and Sun, Xiaodong and Li, Rong and Wang, Xinguo and Kuang, Fenglei and Lv, Jing and Niu, Zhili and PHOENIX Study Grp and PHOENIX Study Group
American Journal of Ophthalmology, ISSN 0002-9394, 01/2019, Volume 197, pp. 156 - 167
Age-related macular degeneration (AMD) can cause irreversible vision loss leading to blindness. We aim to evaluate the efficacy and safety of intravitreal... 
THERAPY | PHARMACOKINETICS | EFFICACY | INJECTION | SAFETY | VEGF | OPHTHALMOLOGY | RANIBIZUMAB | Macular degeneration | Physiological aspects | Care and treatment | Endothelial growth factors | Blindness | Cataracts | Edema | Diabetic retinopathy | Heart attacks | Surgery | Ophthalmology | Vascular endothelial growth factor | Hemorrhage | Drug dosages | Age
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7. Full Text De novo transcriptome assembly based on RNA-seq and dynamic expression of key enzyme genes in loganin biosynthetic pathway of Cornus officinalis
by Bai, Chengke and Wu, Yongmei and Cao, Bo and Xu, Jun and Li, Guishuang
Tree Genetics & Genomes, ISSN 1614-2942, 8/2018, Volume 14, Issue 4, pp. 1 - 14
Cornus officinalis Sieb. et Zucc. is a small tree that is recognized with notable medicinal, economic, and ecological values. It has been used as traditional... 
Life Sciences | Biotechnology | Plant Breeding/Biotechnology | Cornus officinalis | RNA-seq | Plant Genetics and Genomics | Forestry | Transcriptome | Loganin | Tree Biology | RESOURCES | CYTOCHROME-P450 | COLLECTION | FRUIT-DEVELOPMENT | INDOLE ALKALOID BIOSYNTHESIS | HORTICULTURE | GERANIOL 10-HYDROXYLASE | METABOLISM | ANNOTATION | GENETICS & HEREDITY | DIVERSITY | FORESTRY | TOOL | RNA sequencing | Enzymes | Medical colleges | RNA | Analysis | Genes | Genetic research | Gene expression | Transcription factors | Hydroxylase | Traditional Chinese medicine | Pharmacology | Ribonucleic acid--RNA | Molecular chains | Gene sequencing | Fruits | Herbal medicine | Leaves | Glycosides | Pericarp | Chemical synthesis | Assembly
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8. Full Text Less Conserved LRRs Is Important for BRI1 Folding
by Hou, Q and Saima, S and Ren, H and Ali, K and Bai, CK and Wu, G and Li, GS
FRONTIERS IN PLANT SCIENCE, ISSN 1664-462X, 05/2019, Volume 10, p. 634
Brassinosteroid insensitive 1 (BRI1) is a multidomain plant leucine-rich repeat receptor-like kinase (LRR-RLK), belongs to the LRR X subfamily. BRI1 perceives... 
ACTIVATION | LRRs | Arabidopsis | CRYSTAL-STRUCTURE | PROTEIN-KINASE | BRI1 | DEFECTIVE BRASSINOSTEROID RECEPTOR | GENE ENCODES | FAMILY | PLANT SCIENCES | PERCEPTION | less conserved | HORMONE | DIFFERENTIATION | endoplasmic reticulum
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9. Full Text The medicinal active ingredients and their associated key enzyme genes are differentially regulated at different growth stages in Cornus officinalis and Cornus controversa
by Yang, Jingjing and Cao, Bo and Xue, Ying and Liang, Hui and Wu, Yongmei and Zhao, Niping and Hu, Danni and Gao, Pufan and Li, Guishuang and Bai, Chengke
Industrial Crops & Products, ISSN 0926-6690, 12/2019, Volume 142, p. 111858
Revealing the dynamic accumulation and synthesizing mechanism of medicinal active ingredients will be of great significance for the evaluation and utilization... 
Medicinal crops | Active ingredient | Gene expression | Fruit trait
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10. Full Text Modeling habitat distribution ofCornus officinaliswith Maxent modeling and fuzzy logics in China
by Cao, Bo and Bai, Chengke and Zhang, Linlin and Li, Guishuang and Mao, Mingce
Journal of Plant Ecology, ISSN 1752-9921, 12/2016, Volume 9, Issue 6, pp. 742 - 751
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11. Full Text Chinese Cornus officinalis: genetic resources, genetic diversity and core collection
by Li, Guishuang and Zhang, Longjin and Bai, Chengke
Genetic Resources and Crop Evolution, ISSN 0925-9864, 12/2012, Volume 59, Issue 8, pp. 1659 - 1671
Cornus officinalis is plant species that is widely used in traditional Chinese medicine. To help the efficient utilization and conservation of this species,... 
Life Sciences | Plant Systematics/Taxonomy/Biogeography | Cornus officinalis | Plant Physiology | Agriculture | Genetic diversity | ISSR | LDSS | Plant Sciences | Core collection | Germplasm resource | Plant Genetics & Genomics | AGRONOMY | MULTILOCUS GENOTYPE DATA | RAPD | POPULATIONS | INFERENCE | ACCESSIONS | GENOME | REPEAT ISSR MARKERS | PLANT SCIENCES | CONSERVATION | Wildlife conservation | Analysis | Genes | Genetic research | Medicine, Chinese | Universities and colleges | Biological diversity | Cluster analysis | Medicinal plants | Genetic resources | Traditional Chinese medicine | Resource conservation | Biodiversity | Loci | Herbal medicine | Organic chemistry | Species diversity | Germplasm | Genetic analysis | Alleles | S gene | Strategy | Collection | Variation | Collections
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12. Effects of drought stress on hybrids of vigna radiata at germination stage
by Saima, Shehzadi and Li, Guishuang and Wu, Guang
Acta Biologica Hungarica, ISSN 0236-5383, 12/2018, Volume 69, Issue 4, pp. 481 - 492
Drought is one the critical abiotic factors that reduces the germination, growth and yield of crops. Therefore the present project was designed with the... 
Legumes | Germination stress tolerance index | PEG | Water stress | Dry matter stress index | TOLERANCE | SEEDLING GROWTH | legumes | dry matter stress index | WHEAT | ACCESSIONS | L. CULTIVARS | SALT | germination stress tolerance index | RESPONSES | BIOLOGY | RESISTANCE
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13. Full Text Enhancing the field emission properties of Se-doped GaN nanowires
by Li, Enling and Wu, Guishuang and Cui, Zhen and Ma, Deming and Shi, Wei and Wang, Xiaolin
Nanotechnology, ISSN 0957-4484, 05/2016, Volume 27, Issue 26, pp. 265707 - 265714
Pure and Se-doped GaN nanowires (NWs) are synthesized on Pt-coated Si(111) substrates via chemical vapor deposition. The GaN NWs exhibit a uniform density with... 
aN nanowire | work function | field emission | Se-doped | PHYSICS, APPLIED | PHOTOLUMINESCENCE | GaN nanowire | MATERIALS SCIENCE, MULTIDISCIPLINARY | GROWTH | ENHANCEMENT | NANOSCIENCE & NANOTECHNOLOGY | Work functions | Fermi level | Fermi surfaces | Mathematical analysis | Density functional theory | Field emission | Nanowires | Density
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14. Down-regulation of miR-30b reduces cardiomyocyte apoptosis by targeting Bcl-2 in diabetic cardiomyopathy
by Diao, XZ and Li, GS
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, ISSN 1936-2625, 2017, Volume 10, Issue 5, pp. 5296 - 5305
Diabetic cardiomyopathy (DCM) is a major complication of diabetes that contributes to the subsequent development of heart failure and increased mortality.... 
Bcl-2 | diabetic cardiomyopathy (DCM) | miR-30b | ACTIVATION | apoptosis | PATHOLOGY | HEART | HYPERGLYCEMIA | ONCOLOGY | Down-regulation | UP-REGULATION | EXPRESSION | TRANSGENIC MICE
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15. Full Text Does Preoperative T1 Slope and Cervical Lordosis Mismatching Affect Surgical Outcomes After Laminoplasty in Patients with Cervical Spondylotic Myelopathy?
by Rao, Hongming and Huang, Yuming and Lan, Zhibin and Xu, Weihong and Xu, Zhengquan and Li, Guishuang
World Neurosurgery, ISSN 1878-8750, 10/2019, Volume 130, pp. e687 - e693
To assess whether preoperative T1 slope and cervical lordosis mismatching affect the surgical outcomes of patients with cervical spondylotic myelopathy (CSM)... 
Sagittal alignment | Laminoplasty | Kyphotic alignment change | C2–C7 lordosis | Cervical spondylotic myelopathy | T1 slope | DEFORMITY | SURGERY | PREDICTOR | FOLLOW-UP | C2-C7 lordosis | CLINICAL NEUROLOGY | OPEN-DOOR LAMINOPLASTY | SAGITTAL BALANCE | ALIGNMENT | SPINE | CURVATURE | Medical colleges | Lordosis | Care and treatment | Analysis | Patient outcomes
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16. Full Text Genetic diversity and sampling strategy of Scutellaria baicalensis germplasm resources based on ISSR
by Bai, Chengke and Wen, Miaomiao and Zhang, Longjin and Li, Guishuang
Genetic Resources and Crop Evolution, ISSN 0925-9864, 6/2013, Volume 60, Issue 5, pp. 1673 - 1685
Destruction in wild resource and decline in genetic diversity of Scutellaria baicalensis are becoming a big problem urgently needed be dealt in China. To help... 
Life Sciences | Sampling strategy | Plant Systematics/Taxonomy/Biogeography | Scutellaria baicalensis Georgi | Plant Physiology | Agriculture | Genetic diversity | ISSR | LDSS | Plant Sciences | Plant Genetics & Genomics | AGRONOMY | MULTILOCUS GENOTYPE DATA | MARKERS | WOGONIN | POPULATIONS | HUMAN CANCER-CELLS | INFERENCE | PLANT SCIENCES | CONSTRUCTING CORE COLLECTIONS | Analysis | Universities and colleges | Biological diversity | Cluster analysis | Medicinal plants | Populations | Gels | Plant resources | Herbal medicine | Germplasm | Primers | Genetic analysis | Reliability analysis | Strategy | Collection | Sampling | Polymorphism
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17. Full Text Heterogeneous virulence of pandemic 2009 influenza H1N1 virus in mice
by Farooqui, Amber and Leon, Alberto J and Lei, Yanchang and Wang, Pusheng and Huang, Jianyun and Tenorio, Raquel and Dong, Wei and Rubino, Salvatore and Lin, Jie and Li, Guishuang and Zhao, Zhen and Kelvin, David J
Virology Journal, ISSN 1743-422X, 2012, Volume 9, Issue 1, pp. 104 - 104
Background: Understanding the pathogenesis of influenza infection is a key factor leading to the prevention and control of future outbreaks. Pandemic 2009... 
Clinical presentation | Pandemic H1N1 influenza | Pathogenesis | Virulence | Host adaptation | Viral polymerase | Viral heterogeneity | PB2 | HOST-RANGE | POLYMERASE | DETERMINANT | A VIRUS | RESPONSES | TRANSMISSION | REPLICATION | VIROLOGY | ADAPTATION | Cell Line | Humans | Orthomyxoviridae Infections - pathology | Molecular Sequence Data | Influenza A Virus, H1N1 Subtype - pathogenicity | Viral Proteins | Sequence Analysis, DNA | Polymorphism, Genetic | Animals | Hospitals | RNA, Viral - genetics | Virus Replication | China | Influenza, Human - virology | Mice | RNA Replicase | Orthomyxoviridae Infections - virology | Disease Models, Animal | Influenza viruses | Infection | Epidemics | Analysis | Genomics | Swine influenza | Italy | Virulence (Microbiology)
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18. Full Text Angiotensin-(1–7) suppresses hepatocellular carcinoma growth and angiogenesis via complex interactions of angiotensin II type 1 receptor, angiotensin II type 2 receptor and mas receptor
by Liu, Yanping and Li, Bin and Wang, Ximing and Li, Guishuang and Shang, Rui and Yang, Jianmin and Wang, Jiali and Zhang, Meng and Chen, Yuguo and Zhang, Yun and Zhang, Cheng and Hao, Panpan
Molecular Medicine, ISSN 1076-1551, 2015, Volume 21, Issue 1, pp. 626 - 636
We recently confirmed that angiotensin II (Ang II) type 1 receptor (AT(1)R) was overexpressed in hepatocellular carcinoma tissue using a murine hepatoma model.... 
TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITS GROWTH | CELL PROLIFERATION | MICROVESSEL DENSITY | TUMOR ANGIOGENESIS | CELL BIOLOGY | BREAST-CANCER | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | PROSTATE-CANCER | EXPRESSION | Phosphorylation | Apoptosis - drug effects | Humans | Neovascularization, Pathologic - pathology | Mitogen-Activated Protein Kinase 11 - metabolism | Receptor, Angiotensin, Type 1 - genetics | Carcinoma, Hepatocellular - drug therapy | Receptor, Angiotensin, Type 1 - biosynthesis | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Gene Expression Regulation, Neoplastic - drug effects | Mitogen-Activated Protein Kinase 11 - genetics | Receptor, Angiotensin, Type 2 - genetics | Liver Neoplasms - genetics | Peptide Fragments - administration & dosage | Receptor, Angiotensin, Type 2 - biosynthesis | Angiotensin I - administration & dosage | Liver Neoplasms - drug therapy | Hep G2 Cells | Xenograft Model Antitumor Assays | Animals | Neovascularization, Pathologic - drug therapy | Carcinoma, Hepatocellular - pathology | Neovascularization, Pathologic - genetics | Cell Proliferation - drug effects | Mice
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