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by Zhang, ZH and Li, MD
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 06/2019, Volume 294, Issue 25, pp. 9720 - 9721
Adropin is a liver-secreted peptide that is crucial for metabolic health. However, the molecular functions and clinical significance of adropin have not been... 
ADROPIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | Editors' Picks Highlights
Journal Article
Nature communications, ISSN 2041-1723, 01/2020, Volume 11, Issue 1, pp. 181 - 15
Excessive visceral fat accumulation is a primary risk factor for metabolically unhealthy obesity and related diseases. The visceral fat is highly susceptible... 
Obesity | Phosphorylation | Adipose tissue | N-Acetylglucosamine | Homeostasis | Lipids | Glucose | Risk analysis | Lipolysis | Risk factors | High fat diet | Proteins | Diet | Post-translation | Nutrient availability | Nutrients | Droplets
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8007 - 9
In previous studies, miR-29s showed tumor suppressor properties against lung cancer, which improved the survival of patients upon the administration of... 
Survival analysis | Chemotherapy | Cell survival | Lung cancer | AKT2 protein | Non-small cell lung carcinoma | Tumor suppressor genes | AKT protein | Patients | Cisplatin | 1-Phosphatidylinositol 3-kinase
Journal Article
Yale Journal of Biology and Medicine, ISSN 0044-0086, 03/2011, Volume 84, Issue 1, pp. 1 - 7
The 2010 Lasker Award for basic medical research was shared by Douglas Coleman and Jeffery Friedman for their discovery of leptin, a breakthrough that revealed... 
Endocrine System - physiology | Animals | Hypothalamus - physiology | Humans | Leptin - metabolism | Awards and Prizes | Homeostasis | Leptin - genetics | Body Weight - genetics | Neural Pathways - physiology | Obesity - genetics | Review
Journal Article
Journal Article
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 10/2017, Volume 21, Issue 2, pp. 393 - 402
Deterioration of metabolic health is a hallmark of aging and generally assumed to be detrimental to longevity. Exposure to a high-calorie diet impairs... 
metaflammation | metabolic health | calorie restriction | inflammation | fatty acid binding protein | aging | de novo lipogenesis | diabetes | obesity | LIFE-SPAN | RESPONSES | DETERIORATION | INFLAMMATION | CALORIC RESTRICTION | RESISTANCE | FAT | ATHEROSCLEROSIS | DEFICIENT MICE | INSULIN-RECEPTOR GENE | CELL BIOLOGY
Journal Article
Journal of the American Statistical Association, ISSN 0162-1459, 07/2017, Volume 112, Issue 519, pp. 921 - 932
Characterizing the functional relevance of transcription factors (TFs) in different biological contexts is pivotal in systems biology. Given the massive amount... 
Topic modeling | Association study | Genomic data | Semiparametric modeling | CHIP-SEQ | TRANSCRIPTION FACTORS | SETDB1 | C-MYC | PAX-5 | STATISTICS & PROBABILITY | CANCER | MELANOMA | REPRESSION | GENE-EXPRESSION | MIDBRAIN
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2017, Volume 65, Issue 2, pp. 296 - 309
Journal Article