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1. Full Text Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
by Franke, Ane and McGovern, Dermot P. B and Barrett, Jeffrey C and Wang, Kai and Radford-Smith, Graham L and Ahmad, Tariq and Lees, Charlie W and Balschun, Tobias and Lee, James and Roberts, Rebecca and Anderson, Carl A and Bis, Joshua C and Bumpstead, Suzanne and Ellinghaus, David and Festen, Eleonora M and Georges, Michel and Green, Todd and Haritunians, Talin and Jostins, Luke and Latiano, Anna and Mathew, Christopher G and Montgomery, Grant W and Prescott, Natalie J and Raychaudhuri, Soumya and Rotter, Jerome I and Schumm, Philip and Sharma, Yashoda and Simms, Lisa A and Taylor, Kent D and Whiteman, David and Wijmenga, Cisca and Baldassano, Robert N and Barclay, Murray and Bayless, Theodore M and Brand, Stephan and Büning, Carsten and Cohen, Albert and Colombel, Jean-Frederick and Cottone, Mario and Stronati, Laura and Denson, Ted and de Vos, Martine and D'Inca, Renata and Dubinsky, Marla and Edwards, Cathryn and Florin, Tim and Franchimont, Denis and Gearry, Richard and Glas, Jürgen and van Gossum, Ane and Guthery, Stephen L and Halfvarson, Jonas and Verspaget, Hein W and Hugot, Jean-Pierre and Karban, Amir and Laukens, Debby and Lawrance, Ian and Lemann, Marc and Levine, Arie and Libioulle, Cecile and Louis, Edouard and Mowat, Craig and Newman, William and Panés, Julián and Phillips, Anne and Proctor, Deborah D and Regueiro, Miguel and Russell, Richard and Rutgeerts, Paul and Sanderson, Jeremy and Sans, Miquel and Seibold, Frank and Steinhart, A. Hillary and Stokkers, Pieter C. F and Torkvist, Leif and Kullak-Ublick, Gerd and Wilson, David and Walters, Thomas and Targan, Stephan R and Brant, Steven R and Rioux, John D and D'Amato, Mauro and Weersma, Rinse K and Kugathasan, Subra and Griffiths, Anne M and Mansfield, John C and Vermeire, Severine and Duerr, Richard H and Silverberg, Mark S and Satsangi, Jack and Schreiber, Stefan and Cho, Judy H and Annese, Vito and Hakonarson, Hakon and Daly, Mark J and Parkes, Miles
Nature genetics, ISSN 1061-4036, 2010, Volume 42, Issue 12, pp. 1118 - 1125
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Other diseases. Semiology | Genetic Variation | Crohn Disease - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Humans | Computational Biology | Genetic Loci - genetics | Crohn Disease - etiology | Genome, Human - genetics | Genetic Linkage | Care and treatment | Methyltransferases | Physiological aspects | Disease susceptibility | Genetic aspects | Crohn's disease | Research | Risk factors | Inflammatory bowel disease | Genetics | Genomics | Meta-analysis | Index Medicus | Medicin och hälsovetenskap
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2. Full Text Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
by Anderson, Carl A and Boucher, Gabrielle and Lees, Charlie W and Franke, Ane and D'Amato, Mauro and Taylor, Kent D and Lee, James C and Goyette, Philippe and Imielinski, Marcin and Latiano, Anna and Lagacé, Caroline and Scott, Regan and Amininejad, Leila and Bumpstead, Suzannah and Baidoo, Leonard and Baldassano, Robert N and Barclay, Murray and Bayless, Theodore M and Brand, Stephan and Büning, Carsten and Colombel, Jean-Frédéric and Denson, Lee A and de Vos, Martine and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Fehrmann, Rudolf S. N and Floyd, James A. B and Florin, Timothy and Franchimont, Denis and Franke, Lude and Georges, Michel and Glas, Jürgen and Glazer, Nicole L and Guthery, Stephen L and Haritunians, Talin and Hayward, Nicholas K and Hugot, Jean-Pierre and Jobin, Gilles and Laukens, Debby and Lawrance, Ian and Lémann, Marc and Levine, Arie and Libioulle, Cecile and Louis, Edouard and McGovern, Dermot P and Milla, Monica and Montgomery, Grant W and Morley, Katherine I and Mowat, Craig and Ng, Aylwin and Newman, William and Ophoff, Roel A and Papi, Laura and Palmieri, Orazio and Peyrin-Biroulet, Laurent and Panés, Julián and Phillips, Anne and Prescott, Natalie J and Proctor, Deborah D and Roberts, Rebecca and Russell, Richard and Rutgeerts, Paul and Sanderson, Jeremy and Sans, Miquel and Schumm, Philip and Seibold, Frank and Sharma, Yashoda and Simms, Lisa A and Seielstad, Mark and Steinhart, A. Hillary and Targan, Stephan R and van den Berg, Leonard H and Vatn, Morten and Verspaget, Hein and Walters, Thomas and Wijmenga, Cisca and Wilson, David C and Westra, Harm-Jan and Xavier, Ramnik J and Zhao, Zhen Z and Ponsioen, Cyriel Y and Andersen, Vibeke and Torkvist, Leif and Gazouli, Maria and Anagnou, Nicholas P and Karlsen, Tom H and Kupcinskas, Limas and Sventoraityte, Jurgita and Mansfield, John C and Kugathasan, Subra and Silverberg, Mark S and Halfvarson, Jonas and Rotter, Jerome I and Mathew, Christopher G and Griffiths, Anne M and Gearry, Richard and Ahmad, Tariq and Brant, Steven R and Chamaillard, Mathias and ...
Nature genetics, ISSN 1061-4036, 2011, Volume 43, Issue 3, pp. 246 - 252
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Other diseases. Semiology | Crohn Disease - genetics | Risk | Genome-Wide Association Study | Humans | Colitis, Ulcerative - genetics | Genetic aspects | Disease susceptibility | Research | Risk factors | Ulcerative colitis | Meta-analysis | Studies | Inflammatory bowel disease | Celiac disease | Genetics | Genomics | Genes | Index Medicus | Medicin och hälsovetenskap
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3. Full Text Genetics of ulcerative colitis: the come-back of interleukin 10
by Louis, Edouard and Libioulle, Cecile and Reenaers, Catherine and Belaiche, Jacques and Georges, Michel
Gut, ISSN 0017-5749, 09/2009, Volume 58, Issue 9, pp. 1173 - 1176
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Medical sciences | Other diseases. Semiology | Crohn Disease - genetics | Genome-Wide Association Study | Interleukin-10 - deficiency | Humans | Colitis, Ulcerative - genetics | Colitis, Ulcerative - immunology | Crohn Disease - immunology | Animals | Intestinal Mucosa - immunology | Interleukin-10 - genetics | Models, Animal | Mice | Polymorphism, Single Nucleotide | Interleukin-10 - immunology | Interleukin-10 | Physiological aspects | Development and progression | Genetic aspects | Models | Risk factors | Ulcerative colitis | Genomes | Gene expression | Crohns disease | Defects | Prevention | Studies | Inflammatory bowel disease | Probiotics | Rodents | Genetics | Colon | Endoplasmic reticulum | Binding sites | Index Medicus | Abridged Index Medicus
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4. Full Text Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
by Baba, Nobuyasu and Villani, Alexandra-Chloé and Belaiche, Jacques and Rutgeerts, Paul and Louis, Edouard and Fortin, Paul R and Silverberg, Mark S and Gaudet, Daniel and Bitton, Alain and Libioulle, Cécile and Langelier, Diane and Vermeire, Severine and Lemire, Mathieu and Fortin, Geneviève and Sarfati, Marika and Cohen, Albert and Collette, Catherine and Franchimont, Denis and Wither, Joan E and Hudson, Thomas J and Rioux, John D
Nature genetics, ISSN 1061-4036, 01/2009, Volume 41, Issue 1, pp. 71 - 76
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Other diseases. Semiology | Care and treatment | Crohn's disease | Genetic aspects | Disease susceptibility | Research | Single nucleotide polymorphisms | Risk factors | Inflammatory bowel disease | Studies | Confidence intervals | Medical research | Genetics | Kidney diseases | Methods | Crohns disease | Index Medicus
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5. Full Text A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants
by Sharma, Manu and Ioannidis, John P A and Aasly, Jan O and Annesi, Grazia and Brice, Alexis and Bertram, Lars and Bozi, Maria and Barcikowska, Maria and Crosiers, David and Clarke, Carl E and Facheris, Maurizio F and Farrer, Matthew and Garraux, Gaetan and Gispert, Suzana and Auburger, Georg and Vilariño-Güell, Carles and Hadjigeorgiou, Georgios M and Hicks, Andrew A and Hattori, Nobutaka and Jeon, Beom S and Jamrozik, Zygmunt and Krygowska-Wajs, Anna and Lesage, Suzanne and Lill, Christina M and Lin, Juei-Jueng and Lynch, Timothy and Lichtner, Peter and Lang, Anthony E and Libioulle, Cecile and Murata, Miho and Mok, Vincent and Jasinska-Myga, Barbara and Mellick, George D and Morrison, Karen E and Meitnger, Thomas and Zimprich, Alexander and Opala, Grzegorz and Pramstaller, Peter P and Pichler, Irene and Park, Sung Sup and Quattrone, Aldo and Rogaeva, Ekaterina and Ross, Owen A and Stefanis, Leonidas and Stockton, Joanne D and Satake, Wataru and Silburn, Peter A and Strom, Tim M and Theuns, Jessie and Tan, Eng- King and Toda, Tatsushi and Tomiyama, Hiroyuki and Uitti, Ryan J and Van Broeckhoven, Christine and Wirdefeldt, Karin and Wszolek, Zbigniew and Xiromerisiou, Georgia and Yomono, Harumi S and Yueh, Kuo-Chu and Zhao, Yi and Gasser, Thomas and Maraganore, Demetrius and Krüger, Rejko and GEOPD Consortium and GEOPD consortium and on behalf of GEOPD consortium
Journal of medical genetics, ISSN 0022-2593, 11/2012, Volume 49, Issue 11, pp. 721 - 726
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Neurology | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Medical genetics | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Genetic Predisposition to Disease | Genetic Association Studies | Vesicular Transport Proteins - metabolism | Humans | Risk Factors | Vesicular Transport Proteins - genetics | Female | Male | Mutation | Parkinson Disease - genetics | Usage | Parkinson's disease | Genetic aspects | Diagnosis | Research | Risk factors | Genetic screening | Index Medicus | Genetic epidemiology | Parkinson-s disease | Complex traits | Genetics | Genome-wide | 1506 | Genotype-Phenotype Correlations | Medicin och hälsovetenskap
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6. Full Text Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
by Barrett, Jeffrey C and Hansoul, Sarah and Nicolae, Dan L and Cho, Judy H and Duerr, Richard H and Rioux, John D and Brant, Steven R and Silverberg, Mark S and Taylor, Kent D and Barmada, M Michael and Bitton, Alain and Dassopoulos, Themistocles and Datta, Lisa Wu and Green, Todd and Griffiths, Anne M and Kistner, Emily O and Murtha, Michael T and Regueiro, Miguel D and Rotter, Jerome I and Schumm, L Philip and Steinhart, A Hillary and Targan, Stephan R and Xavier, Ramnik J and Libioulle, Cécile and Sandor, Cynthia and Lathrop, Mark and Belaiche, Jacques and Dewit, Olivier and Gut, Ivo and Heath, Simon and Laukens, Debby and Mni, Myriam and Rutgeerts, Paul and Van Gossum, André and Zelenika, Diana and Franchimont, Denis and Hugot, Jean-Pierre and De Vos, Martine and Vermeire, Severine and Louis, Edouard and Cardon, Lon R and Anderson, Carl A and Drummond, Hazel and Nimmo, Elaine and Ahmad, Tariq and Prescott, Natalie J and Onnie, Clive M and Fisher, Sheila A and Marchini, Jonathan and Ghori, Jilur and Bumpstead, Suzannah and Gwilliam, Rhian and Tremelling, Mark and Deloukas, Panos and Mansfield, John and Jewell, Derek and Satsangi, Jack and Mathew, Christopher G and Parkes, Miles and Georges, Michel and Daly, Mark J and Wellcome Trust Case Control and NIDDK IBD Genetics Consortium and Belgian-French IBD Consortium and Wellcome Trust Case Control Consortium and the NIDDK IBD Genetics Consortium and the Belgian-French IBD Consortium and the Wellcome Trust Case Control Consortium
Nature genetics, ISSN 1061-4036, 2008, Volume 40, Issue 8, pp. 955 - 962
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Other diseases. Semiology | Crohn Disease - genetics | Genetic Predisposition to Disease | Genome, Human | Quantitative Trait Loci | Humans | Physiological aspects | Crohn's disease | Genetic aspects | Research | Genetic susceptibility | Risk factors | Inflammatory bowel disease | Studies | Medical research | Genetics | Genomics | Crohns disease | Index Medicus
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7. Full Text Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease
by Lathrop, Mark and O'Morain, Colm and Tysk, Curt and Zelenika, Diana and Hugot, Jean-Pierre and Del-Favero, Jurgen and Vermeire, Severine and Colombel, Jean-Frédéric and Nakamura, Kayo and Dewit, Olivier and Finkel, Yigael and Franchimont, Denis and Laukens, Debby and Lémann, Marc and Mni, Myriam and Momozawa, Yukihide and Louis, Edouard and Goossens, Dirk and Libioulle, Cécile and Cleynen, Isabelle and Reenaers, Catherine and Coppieters, Wouter and Gassull, Miquel A and Amininejad, Leila and Almer, Sven and de Vos, Martine and de Rijk, Peter and Georges, Michel and Rutgeerts, Paul
Nature genetics, ISSN 1061-4036, 01/2011, Volume 43, Issue 1, pp. 43 - 47
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Other diseases. Semiology | Genetic Variation | Crohn Disease - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Phenotype | Humans | Inflammatory Bowel Diseases - genetics | Nod2 Signaling Adaptor Protein - genetics | Polymorphism, Single Nucleotide | Receptors, Interleukin - genetics | Sequence Analysis, DNA | Case-Control Studies | Prevention | Inflammatory bowel diseases | Genes | Physiological aspects | Genetic aspects | Research | Single nucleotide polymorphisms | Studies | Confidence intervals | Inflammatory bowel disease | Candidates | Genomics | Genetics | Standard deviation | Index Medicus | Medicin och hälsovetenskap
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