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bile acids and salts - metabolism (2) 2
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Journal of Clinical Investigation, ISSN 0021-9738, 04/2013, Volume 123, Issue 4, pp. 1513 - 1530
Patients with cholestatic disease exhibit pruritus and analgesia, but the mechanisms underlying these symptoms are unknown. We report that bile acids, which... 
MEDICINE, RESEARCH & EXPERIMENTAL | GENE-RELATED PEPTIDE | INTRATHECAL MORPHINE | SYNAPTIC-TRANSMISSION | GPBAR1 TGR5 | LEUCINE-ENKEPHALIN | SPINAL-CORD | SUBSTANCE-P | CEREBROSPINAL-FLUID | SENSORY NEURONS | RAT MODEL | Spinal Cord - secretion | Bile Acids and Salts - pharmacology | Opioid Peptides - physiology | Spinal Cord - metabolism | Cholestasis - complications | Cholestasis - metabolism | Receptors, G-Protein-Coupled - metabolism | Capsaicin - pharmacology | Male | Receptors, G-Protein-Coupled - agonists | Pain - metabolism | Action Potentials | Pain Perception - drug effects | Gastrin-Releasing Peptide - secretion | Pain - etiology | Female | Pruritus - etiology | Neurons - metabolism | Neurons - drug effects | Single-Cell Analysis | Enkephalin, Leucine - secretion | Receptors, G-Protein-Coupled - physiology | Gene Expression | Mice, Inbred C57BL | Cells, Cultured | Rats | Bile Acids and Salts - metabolism | Organ Specificity | Opioid Peptides - metabolism | Rats, Sprague-Dawley | Ganglia, Spinal - secretion | Mice, Knockout | Macrophages - metabolism | Patch-Clamp Techniques | Pruritus - metabolism | Animals | Ganglia, Spinal - pathology | Dermis - pathology | Mice | Receptors, G-Protein-Coupled - genetics | Bile Acids and Salts - physiology | Ganglia, Spinal - drug effects | Ganglia, Spinal - metabolism | Complications and side effects | Jaundice, Obstructive | Bile acids | Pain | Development and progression | Pruritus | Health aspects | Cholestasis
Journal Article
Hepatology (Baltimore, Md.), ISSN 0270-9139, 2016, Volume 63, Issue 4, pp. 1287 - 1298
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 4, pp. S-102 - S-102
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 05/2011, Volume 300, Issue 5, pp. 790 - 798
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2017, Volume 198, Issue 9, pp. 3565 - 3575
G-CSF or CSF-3, originally defined as a regulator of granulocyte lineage development via its cell surface receptor (G-CSFR), can play a role in inflammation,... 
RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | IN-VITRO | COLONY-STIMULATING FACTOR | NEUTROPHIL PRODUCTION | ANTIGEN-INDUCED ARTHRITIS | INFLAMMATORY ARTHRITIS | TNF-ALPHA | IMMUNOLOGY | EXPERIMENTAL OSTEOARTHRITIS | KEY MEDIATOR | Immunotherapy - methods | Arthritis, Experimental - therapy | Humans | Pain Management | Receptors, Granulocyte Colony-Stimulating Factor - genetics | Leukocyte Reduction Procedures | Arthritis, Experimental - chemically induced | Neurons - physiology | Receptors, Granulocyte Colony-Stimulating Factor - metabolism | Neurons - drug effects | Granulocyte Colony-Stimulating Factor - metabolism | Disease Models, Animal | Neutrophils - pathology | Mice, Inbred C57BL | Neutrophils - drug effects | Cells, Cultured | Neutrophils - immunology | Arthritis, Experimental - immunology | Arthritis, Rheumatoid - therapy | Animals | Antigens, Ly - immunology | Antibodies, Blocking - therapeutic use | Mice | Arthritis, Rheumatoid - immunology | Receptors, Granulocyte Colony-Stimulating Factor - immunology | COX-2 inhibitors | Animal models | Neurons | Medical treatment | Neutrophils | Leukocytes (neutrophilic) | Arthritis | Inflammation | Cerebrospinal fluid | Gene expression | Cell surface | Prostaglandin endoperoxide synthase | Polymerase chain reaction | Pain | Dorsal root ganglia | Granulocyte colony-stimulating factor | Interleukin 1 | Monoclonal antibodies | Cyclooxygenase-2 | Leukocytes (granulocytic) | Granulocyte colony-stimulating factor receptors | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0155526
The effect of respiratory tract viral infection on evoked cough in guinea pigs was evaluated. Guinea pigs were inoculated intranasally with either... 
SMOOTH-MUSCLE | RESPIRATORY-TRACT | VIRUS | IODO-RESINIFERATOXIN | MULTIDISCIPLINARY SCIENCES | VAGAL AFFERENT NEURONS | SUBSTANCE-P | EXPRESSION | SENSORY NEURONS | NERVE GROWTH-FACTOR | C-FIBERS | Paramyxoviridae Infections - genetics | Male | Nerve Growth Factors - metabolism | Trachea - metabolism | Trachea - virology | TRPV Cation Channels - metabolism | Paramyxoviridae Infections - virology | Cough - immunology | Gene Expression | Cough - virology | Guinea Pigs | Nerve Fibers, Unmyelinated - physiology | Parainfluenza Virus 3, Human - physiology | Cough - genetics | Nerve Fibers, Unmyelinated - virology | Respiratory Hypersensitivity - complications | Nodose Ganglion - immunology | Nodose Ganglion - virology | Trachea - innervation | Respiratory Hypersensitivity - immunology | TRPV Cation Channels - genetics | Trachea - immunology | Paramyxoviridae Infections - immunology | Respiratory Hypersensitivity - genetics | Animals | Respiratory Hypersensitivity - virology | Nerve Growth Factors - genetics | Paramyxoviridae Infections - complications | Virus diseases | Respiratory tract infections | Complications and side effects | Development and progression | Research | Risk factors | Capsaicin | Capsaicin receptors | Nerve growth factor | Infections | Respiratory tract | Transient receptor potential proteins | Infusion | Receptors | Immunology | Pain | Rodents | Bradykinin | TrkA protein | Respiratory tract diseases | TrkA receptors | Parainfluenza | Trachea | Neurons | Hypersensitivity | Inflammation | Neurotrophic factors | Gene expression | Allergies | Citric acid | Cough | Medicine | Brain-derived neurotrophic factor | Acids | Lungs | Guinea pigs | TrkB receptors | Laboratory animals | Viral infections
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2015, Volume 290, Issue 22, pp. 13875 - 13887
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 147, Issue 6, pp. 1417 - 1428
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 4, pp. S-546 - S-546
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 4, pp. S-41 - S-41
Journal Article
Gastroenterology, ISSN 0016-5085, 04/2015, Volume 148, Issue 4, p. S-546
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 31, pp. E7438 - E7447
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 07/2019, Volume 294, Issue 27, pp. 10649 - 10662
Proteases sustain hyperexcitability and pain by cleaving protease-activated receptor-2 (PAR ) on nociceptors through distinct mechanisms. Whereas trypsin... 
Journal Article