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by Bonnie R Joubert and Janine F Felix and Paul Yousefi and Kelly M Bakulski and Allan C Just and Carrie Breton and Sarah E Reese and Christina A Markunas and Rebecca C Richmond and Cheng-Jian Xu and Wenche Nystad and Gerard H Koppelman and Caroline L Relton and Vincent W V Jaddoe and Allen Wilcox and Erik Melén and Stephanie J London and Leanne K Küpers and Sam S Oh and Cathrine Hoyo and Olena Gruzieva and Cilla Söderhäll and Lucas A Salas and Nour Baïz and Hongmei Zhang and Johanna Lepeule and Carlos Ruiz and Symen Ligthart and Tianyuan Wang and Jack A Taylor and Liesbeth Duijts and Gemma C Sharp and Soesma A Jankipersadsing and Roy M Nilsen and Ahmad Vaez and M Daniele Fallin and Donglei Hu and Augusto A Litonjua and Bernard F Fuemmeler and Karen Huen and Juha Kere and Inger Kull and Monica Cheng Munthe-Kaas and Ulrike Gehring and Mariona Bustamante and Marie José Saurel-Coubizolles and Bilal M Quraishi and Jie Ren and Jörg Tost and Juan R Gonzalez and Marjolein J Peters and Siri E Håberg and Zongli Xu and Joyce B van Meurs and Tom R Gaunt and Marjan Kerkhof and Eva Corpeleijn and Andrew P Feinberg and Celeste Eng and Andrea A Baccarelli and Sara E Benjamin Neelon and Asa Bradman and Simon Kebede Merid and Anna Bergström and Zdenko Herceg and Hector Hernandez-Vargas and Bert Brunekreef and Mariona Pinart and Barbara Heude and Susan Ewart and Jin Yao and Nathanaël Lemonnier and Oscar H Franco and Michael C Wu and Albert Hofman and Wendy McArdle and Pieter Van der Vlies and Fahimeh Falahi and Matthew W Gillman and Lisa F Barcellos and Ashish Kumar and Magnus Wickman and Stefano Guerra and Marie-Aline Charles and John Holloway and Charles Auffray and Henning W Tiemeier and George Davey Smith and Dirkje Postma and Marie-France Hivert and Brenda Eskenazi and Martine Vrijheid and Hasan Arshad and Josep M Antó and Abbas Dehghan and Wilfried Karmaus and Isabella Annesi-Maesano and Jordi Sunyer and Akram Ghantous and Göran Pershagen and ...
American Journal of Human Genetics, ISSN 0002-9297, 04/2016, Volume 98, Issue 4, p. 680
  Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in... 
Pregnancy | Newborn babies | DNA methylation | Genomes | Mothers | Smoking | Meta-analysis
Journal Article
by Ligthart, Symen and Marzi, Carola and Aslibekyan, Stella and Mendelson, Michael M and Conneely, Karen N and Tanaka, Toshiko and Colicino, Elena and Waite, Lindsay L and Joehanes, Roby and Guan, Weihua and Brody, Jennifer A and Elks, Cathy and Marioni, Riccardo and Jhun, Min A and Agha, Golareh and Bressler, Jan and Ward-Caviness, Cavin K and Chen, Brian H and Huan, Tianxiao and Bakulski, Kelly and Salfati, Elias L and WHI-EMPC, Investigators and Fiorito, Giovanni and CHARGE, epigenetics of Coronary Heart Disease and Wahl, Simone and Schramm, Katharina and Sha, Jin and Hernandez, Dena G and Just, Allan C and Smith, Jennifer A and Sotoodehnia, Nona and Pilling, Luke C and Pankow, James S and Tsao, Phil S and Liu, Chunyu and Zhao, Wei and Guarrera, Simonetta and Michopoulos, Vasiliki J and Smith, Alicia K and Peters, Marjolein J and Melzer, David and Vokonas, Pantel and Fornage, Myriam and Prokisch, Holger and Bis, Joshua C and Chu, Audrey Y and Herder, Christian and Grallert, Harald and Yao, Chen and Shah, Sonia and McRae, Allan F and Lin, Honghuang and Horvath, Steve and Fallin, Daniele and Hofman, Albert and Wareham, Nicholas John and Wiggins, Kerri L and Feinberg, Andrew P and Starr, John M and Visscher, Peter M and Murabito, Joanne M and Kardia, Sharon LR and Absher, Devin M and Binder, Elisabeth B and Singleton, Andrew B and Bandinelli, Stefania and Peters, Annette and Waldenberger, Melanie and Matullo, Giuseppe and Schwartz, Joel D and Demerath, Ellen W and Uitterlinden, André G and van, Meurs Joyce BJ and Franco, Oscar H and Chen, Yii-Der Ida and Levy, Daniel and Turner, Stephen T and Deary, Ian J and Ressler, Kerry J and Dupuis, Josée and Ferrucci, Luigi and Ong, Ken and Assimes, Themistocles L and Boerwinkle, Eric and Koenig, Wolfgang and Arnett, Donna K and Baccarelli, Andrea A and Benjamin, Emelia J and Dehghan, Abbas
ISSN 1474-7596, 2016
BACKGROUND: Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenesis of complex diseases. Identifying genetic loci... 
Gene Expression | Genome-Wide Association Study | CHARGE epigenetics of Coronary Heart Disease | C-Reactive Protein | Humans | Epigenesis, Genetic | African Americans | European Continental Ancestry Group | Male | WHI-EMPC Investigators | Inflammation | Genetic Variation | DNA Methylation | Nucleotide Motifs | CpG Islands | Female | Quantitative Trait Loci
Journal Article
by Ligthart, Symen and de Vries, Paul S and Uitterlinden, Ané G and Hofman, Albert and Franco, Oscar H and Chasman, Daniel I and Dehghan, Abbas and Dupuis, Josée and Barbalic, Maja and Bis, Joshua C and Eiriksdottir, Gudny and Lu, Chen and Pellikka, Niina and Wallaschofski, Henri and Kettunen, Johannes and Henneman, Peter and Baumert, Jens and Strachan, David P and Fuchsberger, Christian and Vitart, Veronique and Wilson, James F and Paré, Guillaume and Naitza, Silvia and Rudock, Megan E and Surakka, Ida and De Geus, Eco J. C and Alizadeh, Behrooz Z and Guralnik, Jack M. D and Shuldiner, Alan and Tanaka, Toshiko and Zee, Robert Y. L and Schnabel, Renate B and Nambi, Vijay and Kavousi, Maryam and Ripatti, Samuli and Nauck, Matthias and Smith, Nicholas L and Smith, Albert V and Sundvall, Jouko and Scheet, Paul and Liu, Yongmei and Ruokonen, Aimo and Rose, Lynda M and Larson, Martin G and Hoogeveen, Ron C and Freimer, Nelson B and Teumer, Alexander and Tracy, Russell P and Launer, Lenore J and Buring, Julie E and Yamamoto, Jennifer F and Folsom, Aaron R and Sijbrands, Eric J. G and Pankow, James and Elliott, Paul and Keaney, John F and Sun, Wei and Sarin, Antti-Pekka and Fontes, João D and Badola, Sunita and Astor, Brad C and Pouta, Anneli and Werda, Karl and Greiser, Karin H and Kuss, Oliver and Schwabedissen, Henriette E. Meyer Zu and Thiery, Joachim and Jamshidi, Yalda and Nolte, Ilja M and Soranzo, Nicole and Spector, Timothy D and Völzke, Henry and Parker, Alexander N and Aspelund, Thor and Bates, David and Young, Lauren and Tsui, Kim and Siscovick, David S and Guo, Xiuqing and Rotter, Jerome I and Uda, Manuela and Schlessinger, David and Rudan, Igor and Hicks, Anew A and Penninx, Brenda W and Thorand, Barbara and Gieger, Christian and Coresh, Joe and Willemsen, Gonneke and Harris, Tamara B and Järvelin, Marjo-Riitta and Rice, Kenneth and Radke, Dörte and Salomaa, Veikko and Van Dijk, Ko Willems and Boerwinkle, Eric and Vasan, Ramachanan S and Ferrucci, Luigi and Gibson, Quince D and Bandinelli, Stefania and ...
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3
Pleiotropic genetic variants have independent effects on different phenotypes. C-reactive protein (CRP) is associated with several cardiometabolic phenotypes.... 
Journal Article
Journal Article
Molecular Genetics and Metabolism, ISSN 1096-7192, 08/2014, Volume 112, Issue 4, pp. 317 - 338
Metabolic syndrome (MetS) has become a health and financial burden worldwide. The MetS definition captures clustering of risk factors that predict higher risk... 
Journal Article
by Freitag, Daniel and Butterworth, Adam S and Willeit, Peter and Howson, Joanna M M and Burgess, Stephen and Kaptoge, Stephen and Young, Robin and Ho, Weang Kee and Wood, Angela M and Sweeting, Michael and Spackman, Sarah and Staley, James R and Ramond, Anna and Harshfield, Eric and Nielsen, Sune F and Grande, Peer and Lange, Leslie A and Bown, Matthew J and Jones, Gregory T and Scott, Robert A and Bevan, Steve and Porcu, Eleonora and Thorleifsson, Gudmar and Zeng, Lingyao and Kessler, Thorsten and Nikpay, Majid and Do, Ron and Zhang, Weihua and Hopewell, Jemma C and Kleber, Marcus and Delgado, Graciela E and Nelson, Christopher P and Goel, Anuj and Bis, Joshua C and Dehghan, Abbas and Ligthart, Symen and Smith, Albert V and Qu, Liming and van 't Hof, Femke N G and de Bakker, Paul I W|info:eu-repo/dai/nl/342957082 and Baas, Annette F and van Rij, Ane and Tromp, Gerard and Kuivaniemi, Helena and Ritchie, Marylyn D and Verma, Shefali S and Crawford, Dana C and Malinowski, Jennifer and de Anade, Mariza and Kullo, Iftikhar J and Peissig, Peggy L and McCarty, Catherine A and Böttinger, Erwin P and Gottesman, Omri and Crosslin, David R and Carrell, David S and Rasmussen-Torvik, Laura J and Pacheco, Jennifer A and Huang, Jie and Timpson, Nicholas J and Kettunen, Johannes and Ala-Korpela, Mika and Mitchell, Gary F and Parsa, Afshin and Wilkinson, Ian B and Gorski, Mathias and Li, Yong and Franceschini, Nora and Keller, Margaux F and Ganesh, Santhi K and Langefeld, Carl D and Bruijn, Lucie and Brown, Matthew A and Evans, David M and Baltic, Svetlana and Ferreira, Manuel A and Baurecht, Hansjörg and Weidinger, Stephan and Franke, Ane and Lubitz, Steven A and Müller-Nurasyid, Martina and Felix, Janine F and Smith, Nicholas L and Sudman, Marc and Thompson, Susan D and Zeggini, Eleftheria and Panoutsopoulou, Kalliope and Nalls, Mike A and Singleton, Anew and Polychronakos, Constantin and Bradfield, Jonathan P and Hakonarson, Hakon and Easton, Douglas F and Thompson, Deborah and Tomlinson, Ian P and Dunlop, Malcolm and Hemminki, Kari and Morgan, Gareth and Eisen, Timothy and Goldschmidt, Hartmut and ...
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 04/2015, Volume 3, Issue 4, p. 243
To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1 (IL-1) inhibition, we studied genetic variants that... 
Journal Article
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