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Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2581 - 11
Journal Article
International Journal of Epidemiology, ISSN 0300-5771, 10/2019
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 08/2019, Volume 140, Issue 8, pp. 645 - 657
BACKGROUND:DNA methylation is implicated in coronary heart disease (CHD), but current evidence is based on small, cross-sectional studies. We examined blood... 
coronary artery disease | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | MODEL | epigenetics | HYPOMETHYLATION | gene expression regulation | INSULIN | STROKE | BIASED SELECTION | GENES | CARDIOVASCULAR-DISEASE | genomics | PERIPHERAL VASCULAR DISEASE | coronary heart disease | GENOME-WIDE ASSOCIATION | ARTERY-DISEASE
Journal Article
by Kraja, Aldi T and Liu, Chunyu and Fetterman, Jessica L and Graff, Mariaelisa and Have, Christian Theil and Gu, Charles and Gu, Zhenglong and Yanek, Lisa R and Feitosa, Mary F and Arking, Dan E and Chasman, Daniel I and Young, Kristin and Ligthart, Symen and Hill, W. David and Weiss, Stefan and Luan, Jian’an and Giulianini, Franco and Li-Gao, Ruifang and Hartwig, Fernando P and Lin, Keng-Hung and Lin, Shiow J and Wang, Lihua and Wang, Yujie and Richardson, Tom G and Yao, Jie and Fernandez, Eliana P and Ghanbari, Mohsen and Wojczynski, Mary K and Lee, Wen-Jane and Lee, Joseph H and Argos, Maria and Armasu, Sebastian M and Barve, Ruteja A and Ryan, Kathleen A and An, Ping and Baranski, Thomas J and Bielinski, Suzette J and Bowden, Donald W and Broeckel, Ulrich and Christensen, Cramer and Christensen, Kaare and Chu, Audrey Y and Corley, Janie and Cox, Simon R and Uitterlinden, Andre G and Rivadeneira, Fernando and Cropp, Cheryl D and Daw, E. Warwick and van Heemst, Diana and de las Fuentes, Lisa and Gao, He and Tzoulaki, Ioanna and Ahluwalia, Tarunveer S and de Mutsert, Renée and Emery, Leslie S and Erzurumluoglu, A. Mesut and Perry, James A and Fu, Mao and Forouhi, Nita G and Hai, Yang and Harris, Sarah E and Hemani, Gibran and Hunt, Steven C and Irvin, Marguerite R and Jonsson, Anna E and Justice, Anne E and Kerrison, Nicola D and Larson, Nicholas B and Love-Gregory, Latisha D and Mathias, Rasika A and Nauck, Matthias and Noordam, Raymond and Ong, Ken K and Pankow, James and Patki, Amit and Pattie, Alison and Petersmann, Astrid and Qi, Qibin and Ribel-Madsen, Rasmus and Rohde, Rebecca and Sandow, Kevin and Schnurr, Theresia M and Sofer, Tamar and Starr, John M and Taylor, Adele M and Taylor, Kent D and Teumer, Alexander and Timpson, Nicholas J and de Haan, Hugoline G and Weeke, Peter E and Williams, Christine and Wu, Hongsheng and Yang, Wei and Zeng, Donglin and Witte, Daniel R and Weir, Bruce S and Wareham, Nicholas J and Vestergaard, Henrik and Turner, Stephen T and Torp-Pedersen, Christian and ...
The American Journal of Human Genetics, ISSN 0002-9297, 01/2019, Volume 104, Issue 1, pp. 112 - 138
Journal Article
by Mahajan, Anubha and Taliun, Daniel and Thurner, Matthias and Robertson, Neil R and Torres, Jason M and Rayner, N William and Steinthorsdottir, Valgerdur and Scott, Robert A and Grarup, Niels and Cook, James P and Schmidt, Ellen M and Wuttke, Matthias and Sarnowski, Chloé and Mägi, Reedik and Nano, Jana and Gieger, Christian and Trompet, Stella and Lecoeur, Cécile and Preuss, Michael and Prins, Bram Peter and Guo, Xiuqing and Bielak, Lawrence F and and Bennett, Amanda J and Bork-Jensen, Jette and Brummett, Chad M and Canouil, Mickaël and Eckardt, Kai-Uwe and Fischer, Krista and Kardia, Sharon LR and Kronenberg, Florian and Läll, Kristi and Liu, Ching-Ti and Locke, Adam E and Luan, Jian'an and Ntalla, Ioanna and Nylander, Vibe and Schönherr, Sebastian and Schurmann, Claudia and Yengo, Loïc and Bottinger, Erwin P and Brandslund, Ivan and Christensen, Cramer and Dedoussis, George and Florez, Jose C and ford, Ian and Franco, Oscar H and Frayling, Timothy M and Giedraitis, Vilmantas and Hackinger, Sophie and Hattersley, Andrew T and Herder, Christian and Ikram, M Arfan and Ingelsson, Martin and Jørgensen, Marit E and Jørgensen, Torben and Kriebel, Jennifer and Kuusisto, Johanna and Ligthart, Symen and Lindgren, Cecilia M and Linneberg, Allan and Lyssenko, Valeriya and Mamakou, Vasiliki and Meitinger, Thomas and Mohlke, Karen L and Morris, Andrew D and Nadkarni, Girish and Pankow, James S and Peters, Annette and Sattar, Naveed and Stančáková, Alena and Strauch, Konstantin and Taylor, Kent D and Thorand, Barbara and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Tuomilehto, Jaakko and Witte, Daniel R and Dupuis, Josée and Peyser, Patricia A and Zeggini, Eleftheria and Loos, Ruth J F and Froguel, Philippe and Ingelsson, Erik and Lind, Lars and Groop, Leif and Laakso, Markku and Collins, Francis S and Jukema, J Wouter and Palmer, Colin N A and Grallert, Harald and Metspalu, Andres and Dehghan, Abbas and Köttgen, Anna and Abecasis, Goncalo and Meigs, James B and Rotter, Jerome I and Marchini, Jonathan and Pedersen, Oluf and Hansen, Torben and ...
Nature genetics, ISSN 1061-4036, 11/2018, Volume 50, Issue 11, pp. 1505 - 1513
We aggregated genome-wide genotyping data from 32 European-descent GWAS (74,124 T2D cases, 824,006 controls) imputed to high-density reference panels of... 
Journal Article
by Mahajan, Anubha and Taliun, Daniel and Thurner, Matthias and Robertson, Neil R and Torres, Jason M and Rayner, N William and Payne, Anthony J and Steinthorsdottir, Valgerdur and Scott, Robert A and Grarup, Niels and Cook, James P and Schmidt, Ellen M and Wuttke, Matthias and Sarnowski, Chloé and Mägi, Reedik and Nano, Jana and Gieger, Christian and Trompet, Stella and Lecoeur, Cécile and Preuss, Michael H and Prins, Bram Peter and Guo, Xiuqing and Bielak, Lawrence F and Below, Jennifer E and Bowden, Donald W and Chambers, John Campbell and Kim, Young Jin and Ng, Maggie CY and Petty, Lauren E and Sim, Xueling and Zhang, Weihua and Bennett, Amanda J and Bork-Jensen, Jette and Brummett, Chad M and Canouil, Mickaël and Ec Kardt, Kai-Uwe and Fischer, Krista and Kardia, Sharon LR and Kronenberg, Florian and Läll, Kristi and Liu, Ching-Ti and Locke, Adam E and Luan, Jian'an and Ntalla, Ioanna and Nylander, Vibe and Schönherr, Sebastian and Schurmann, Claudia and Yengo, Loïc and Bottinger, Erwin P and Brandslund, Ivan and Christensen, Cramer and Dedoussis, George and Florez, Jose C and Ford, Ian and Franco, Oscar H and Frayling, Timothy M and Giedraitis, Vilmantas and Hackinger, Sophie and Hattersley, Andrew T and Herder, Christian and Ikram, M Arfan and Ingelsson, Martin and Jørgensen, Marit E and Jørgensen, Torben and Kriebel, Jennifer and Kuusisto, Johanna and Ligthart, Symen and Lindgren, Cecilia M and Linneberg, Allan and Lyssenko, Valeriya and Mamakou, Vasiliki and Meitinger, Thomas and Mohlke, Karen L and Morris, Andrew D and Nadkarni, Girish and Pankow, James S and Peters, Annette and Sattar, Naveed and Stančáková, Alena and Strauch, Konstantin and Taylor, Kent D and Thorand, Barbara and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Tuomilehto, Jaakko and Witte, Daniel R and Dupuis, Josée and Peyser, Patricia A and Zeggini, Eleftheria and Loos, Ruth JF and Froguel, Philippe and Ingelsson, Erik and Lind, Lars and Groop, Leif and Laakso, Markku and Collins, Francis S and Jukema, J Wouter and Palmer, Colin NA and Grallert, Harald and Metspalu, Andres and ...
ISSN 1061-4036, 2018
We aggregated genome-wide genotyping data from 32 European-descent GWAS (74,124 T2D cases, 824,006 controls) imputed to high-density reference panels of... 
Journal Article
by Mahajan, Anubha and Taliun, Daniel and Thurner, Matthias and Robertson, Neil R and Torres, Jason M and Rayner, N. William and Payne, Anthony J and Steinthorsdottir, Valgerdur and Scott, Robert A and Grarup, Niels and Cook, James P and Schmidt, Ellen M and Wuttke, Matthias and Sarnowski, Chloé and Mägi, Reedik and Nano, Jana and Gieger, Christian and Trompet, Stella and Lecoeur, Cécile and Preuss, Michael H and Prins, Bram Peter and Guo, Xiuqing and Bielak, Lawrence F and Below, Jennifer E and Bowden, Donald W and Chambers, John Campbell and Kim, Young Jin and Ng, Maggie C. Y and Petty, Lauren E and Sim, Xueling and Zhang, Weihua and Bennett, Amanda J and Bork-Jensen, Jette and Brummett, Chad M and Canouil, Mickaël and Ec kardt, Kai-Uwe and Fischer, Krista and Kardia, Sharon L. R and Kronenberg, Florian and Läll, Kristi and Liu, Ching-Ti and Locke, Adam E and Luan, Jian’an and Ntalla, Ioanna and Nylander, Vibe and Schönherr, Sebastian and Schurmann, Claudia and Yengo, Loïc and Bottinger, Erwin P and Brandslund, Ivan and Christensen, Cramer and Dedoussis, George and Florez, Jose C and Ford, Ian and Franco, Oscar H and Frayling, Timothy M and Giedraitis, Vilmantas and Hackinger, Sophie and Hattersley, Andrew T and Herder, Christian and Ikram, M. Arfan and Ingelsson, Martin and Jørgensen, Marit E and Jørgensen, Torben and Kriebel, Jennifer and Kuusisto, Johanna and Ligthart, Symen and Lindgren, Cecilia M and Linneberg, Allan and Lyssenko, Valeriya and Mamakou, Vasiliki and Meitinger, Thomas and Mohlke, Karen L and Morris, Andrew D and Nadkarni, Girish and Pankow, James S and Peters, Annette and Sattar, Naveed and Stančáková, Alena and Strauch, Konstantin and Taylor, Kent D and Thorand, Barbara and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Tuomilehto, Jaakko and Witte, Daniel R and Dupuis, Josée and Peyser, Patricia A and Zeggini, Eleftheria and Loos, Ruth J. F and Froguel, Philippe and Ingelsson, Erik and Lind, Lars and Groop, Leif and Laakso, Markku and Collins, Francis S and Jukema, J. Wouter and Palmer, Colin N. A and Grallert, Harald and Metspalu, Andres and ... and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Geriatrik and Klinisk epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Nature Genetics, ISSN 1061-4036, 11/2018, Volume 50, Issue 11, pp. 1505 - 1513
Journal Article
by Ligthart, Symen and Vaez, Ahmad and Võsa, Urmo and Stathopoulou, Maria G and Stathopoulou, Maria and de Vries, Paul S and Prins, Bram P and Prins, Bram and Van der Most, Peter J and Tanaka, Toshiko and Naderi, Elnaz and Rose, Lynda M and Wu, Ying and Karlsson, Robert and Karlsson, Magnus and Barbalic, Maja and Lin, Honghuang and Pool, René and Zhu, Gu and Macé, Aurélien and Sidore, Carlo and Trompet, Stella and Mangino, Massimo and Sabater-Lleal, Maria and Kemp, John P and Abbasi, Ali and Kacprowski, Tim and Verweij, Niek and Smith, Albert V and Smith, Erin N and Smith, George Davey and Huang, Jie and Huang, Tao and Huang, Hongyan and Marzi, Carola and Feitosa, Mary F and Lohman, Kurt K and Kleber, Marcus E and Milaneschi, Yuri and Mueller, Christian and Huq, Mahmudul and Vlachopoulou, Efthymia and Lyytikäinen, Leo-Pekka and Oldmeadow, Christopher and Deelen, Joris and Perola, Markus and Zhao, Jing Hua and Zhao, Jing and Feenstra, Bjarke and Alizadeh, Behrooz Z and Boezen, H. Marike and Franke, Lude and van der Harst, Pim and Navis, Gerjan and Rots, Marianne and Snieder, Harold and Swertz, Morris and Wolffenbuttel, Bruce H.R and Wijmenga, Cisca and Amini, Marzyeh and Benjamin, Emelia J and Benjamin, Emelia and Chasman, Daniel I and Dehghan, Abbas and Ahluwalia, Tarunveer Singh and Ahluwalia, Tarunveer S and Meigs, James and Tracy, Russell and Tracy, Russell P and Bis, Josh and Bis, Joshua C and Eiriksdottir, Gudny and Pankratz, Nathan and Gross, Myron and Rainer, Alex and Wilson, James G and Wilson, James F and Psaty, Bruce M and Dupuis, Josee and Dupuis, Josée and Vaso, Urmo and Lehtimaki, Terho and Koenig, Wolfgang and Jamshidi, Yalda and Siest, Sophie and Uitterlinden, André G and Uitterlinden, Andre G and Abdollahi, Mohammadreza and Schnabel, Renate and Schick, Ursula M and Nolte, Ilja M and Kraja, Aldi and Hsu, Yi-Hsiang and Tylee, Daniel S and Zwicker, Alyson and Uher, Rudolf and Davey-Smith, George and Morrison, Alanna C and Hicks, Andrew and Hicks, Andrew A and ... and CHARGE Inflammation Working Grp and LifeLines Cohort Study and CHARGE Inflammation Working Group and Stockholms universitet and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten
The American Journal of Human Genetics, ISSN 0002-9297, 11/2018, Volume 103, Issue 5, pp. 691 - 706
Journal Article
JAMA CARDIOLOGY, ISSN 2380-6583, 06/2018, Volume 3, Issue 6, pp. 463 - 472
IMPORTANCE Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory cytokine with manifold consequences for mammalian pathophysiology, including... 
RHEUMATOID-ARTHRITIS | DESIGN | CARDIAC & CARDIOVASCULAR SYSTEMS | GENE PROMOTER METHYLATION | EPIGENETIC REGULATION | NLRC5 | FAT | MHC | INHIBITORS | PARP-1 | TWIN
Journal Article