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Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/2017, Volume 490, Issue 3, p. 650
YAP (Yes-associated protein) and TAZ (transcription activator with PDZ binding motif) are important in tissue regeneration and cancer development, highlighting... 
Ubiquitin | Genetic research | Medical colleges | Protein kinases | Genes
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2013, Volume 19, Issue 11, pp. 1478 - 1488
Here we show that Mst1, a proapoptotic kinase, impairs protein quality control mechanisms in the heart through inhibition of autophagy. Stress-induced... 
MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | PROTEIN AGGREGATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHATIDYLINOSITOL 3-KINASE COMPLEXES | KINASE | STARVATION-INDUCED AUTOPHAGY | CELL BIOLOGY | HEMODYNAMIC STRESS | PATHWAY | X-L | CARDIAC-HYPERTROPHY | TUMOR-SUPPRESSOR | Cardiomyopathy, Dilated - pathology | Phosphorylation | Humans | Middle Aged | Protein Multimerization | Molecular Sequence Data | Male | Autophagy - physiology | Young Adult | Proto-Oncogene Proteins c-bcl-2 - metabolism | Myocardial Infarction - pathology | Apoptosis Regulatory Proteins - genetics | Hepatocyte Growth Factor - genetics | Adult | Female | Membrane Proteins - metabolism | Beclin-1 | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Myocytes, Cardiac - cytology | Membrane Proteins - genetics | Apoptosis Regulatory Proteins - chemistry | Mice, Inbred C57BL | bcl-2-Associated X Protein - metabolism | Class III Phosphatidylinositol 3-Kinases - metabolism | Models, Molecular | Rats | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Myocardial Infarction - metabolism | Proto-Oncogene Proteins - deficiency | Cardiomyopathy, Dilated - metabolism | Apoptosis Regulatory Proteins - metabolism | Hepatocyte Growth Factor - metabolism | Mice, Knockout | Hepatocyte Growth Factor - deficiency | Animals | Membrane Proteins - chemistry | Myocytes, Cardiac - metabolism | Class III Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Mice | Apoptosis - physiology | Autophagy (Cytology) | Heart cells | Physiological aspects | Research | Properties | Phosphotransferases | Apoptosis | Cardiomyocytes | Kinases | Cardiomyopathy | Autophagy
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 5127 - 5127
Abstract Background: MicroRNAs are small RNA species that regulate gene expression post-transcriptionally and are aberrantly expressed in many cancers... 
Journal Article
Journal Article
BMB Reports, ISSN 1976-6696, 2018, Volume 51, Issue 5, pp. 209 - 210
NAFLD induces the development of advanced liver diseases such as NASH and liver cancer. Therefore, understanding the mechanism of NAFLD development is critical... 
Liver cancer | IRS2 | Hippo pathway | Hepatic steatosis | AKT signaling
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2017, Volume 127, Issue 9, pp. 3441 - 3461
Journal Article