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by Ally, Adrian and Balasundaram, Miruna and Carlsen, Rebecca and Chuah, Eric and Clarke, Amanda and Dhalla, Noreen and Holt, Robert A and Jones, Steven J.M and Lee, Darlene and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Thiessen, Nina and Cheung, Dorothy and Wong, Tina and Brooks, Denise and Robertson, A. Gordon and Bowlby, Reanne and Mungall, Karen and Sadeghi, Sara and Xi, Liu and Covington, Kyle and Shinbrot, Eve and Wheeler, David A and Gibbs, Richard A and Donehower, Lawrence A and Wang, Linghua and Bowen, Jay and Gastier-Foster, Julie M and Gerken, Mark and Helsel, Carmen and Leraas, Kristen M and Lichtenberg, Tara M and Ramirez, Nilsa C and Wise, Lisa and Zmuda, Erik and Gabriel, Stacey B and Meyerson, Matthew and Cibulskis, Carrie and Murray, Bradley A and Shih, Juliann and Beroukhim, Rameen and Cherniack, Andrew D and Schumacher, Steven E and Saksena, Gordon and Pedamallu, Chandra Sekhar and Chin, Lynda and Getz, Gad and Noble, Michael and Zhang, Hailei and Heiman, David and Cho, Juok and Gehlenborg, Nils and Voet, Douglas and Lin, Pei and Frazer, Scott and Defreitas, Timothy and Meier, Sam and Lawrence, Michael and Kim, Jaegil and Creighton, Chad J and Muzny, Donna and Doddapaneni, HarshaVardhan and Hu, Jianhong and Wang, Min and Morton, Donna and Korchina, Viktoriya and Han, Yi and Dinh, Huyen and Lewis, Lora and Bellair, Michelle and Liu, Xiuping and Santibanez, Jireh and Glenn, Robert and Lee, Sandra and Hale, Walker and Parker, Joel S and Wilkerson, Matthew D and Hayes, D. Neil and Reynolds, Sheila M and Shmulevich, Ilya and Zhang, Wei and Liu, Yuexin and Iype, Lisa and Makhlouf, Hala and Torbenson, Michael S and Kakar, Sanjay and Yeh, Matthew M and Jain, Dhanpat and Kleiner, David E and Dhanasekaran, Renumathy and El-Serag, Hashem B and Yim, Sun Young and Weinstein, John N and Mishra, Lopa and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Cancer Genome Atlas Research Network. Electronic address: wheeler@bcm.edu
Cell (Cambridge), ISSN 0092-8674, 2017, Volume 169, Issue 7, pp. 1327 - 1341.e23
Journal Article
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 11/2018, Volume 321, Issue 1, pp. 69 - 79
IMPORTANCE: Type 2 diabetes is associated with increased cardiovascular (CV) risk. Prior trials have demonstrated CV safety of 3 dipeptidyl peptidase 4 (DPP-4)... 
KIDNEY-DISEASE | MORTALITY | GFR DECLINE | END-POINT | SAXAGLIPTIN | HEART-FAILURE | SITAGLIPTIN | DEATH | OUTCOMES | CKD | MEDICINE, GENERAL & INTERNAL | Hypoglycemic Agents - therapeutic use | Kidney Failure, Chronic - mortality | Cardiovascular Diseases - etiology | Double-Blind Method | Cardiovascular Diseases - prevention & control | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Middle Aged | Risk Factors | Linagliptin - adverse effects | Proportional Hazards Models | Male | Linagliptin - therapeutic use | Glycated Hemoglobin A | Cardiovascular Diseases - mortality | Female | Aged | Diabetes Mellitus, Type 2 - drug therapy | Drug Therapy, Combination | Hypoglycemia - chemically induced | Hypoglycemic Agents - adverse effects | Diabetes Mellitus, Type 2 - complications | Kidney Failure, Chronic - etiology | Type 2 diabetes | Usage | Clinical trials | Research | Risk factors | Complications and side effects | Analysis | Placebos | Linagliptin | Dosage and administration | Kidney diseases | Cardiovascular diseases | Drug therapy | Myocardial infarction | End-stage renal disease | Adjudication | Risk | Effects | Incidence | Vascular diseases | Hemoglobin | Diabetes mellitus (non-insulin dependent) | Urine | Creatinine | Cerebral infarction | Stroke | Kidneys | Peptidase | Epidermal growth factor receptors | Diabetes mellitus | Pancreatitis | Health risks | Hypoglycemia | Insulin | Patients | Placebo effect | Prescription drugs | Renal failure | Infarction | Adults | Diabetes | Online First | Original Investigation
Journal Article
by Seow, Wei Jie and Matsuo, Keitaro and Hsiung, Chao Agnes and Shiraishi, Kouya and Song, Minsun and Kim, Hee Nam and Wong, Maria Pik and Hong, Yun-Chul and Hosgood, H. Dean and Wang, Zhaoming and Chang, I-Shou and Wang, Jiu-Cun and Chatterjee, Nilanjan and Tucker, Margaret and Wei, Hu and Mitsudomi, Tetsuya and Zheng, Wei and Kim, Jin Hee and Zhou, Baosen and Caporaso, Neil E and Albanes, Demetrius and Shin, Min-Ho and Chung, Lap Ping and An, She-Juan and Wang, Ping and Zheng, Hong and Yatabe, Yasushi and Zhang, Xu-Chao and Kim, Young Tae and Shu, Xiao Ou and Kim, Young-Chul and Bassig, Bryan A and Chang, Jiang and Ho, James Chung Man and Ji, Bu Tian and Kubo, Michiaki and Daigo, Yataro and Ito, Hidemi and Momozawa, Yukihide and Ashikawa, Kyota and Kamatani, Yoichiro and Honda, Takayuki and Sakamoto, Hiromi and Kunitoh, Hideo and Tsuta, Koji and Watanabe, Shun-Ichi and Nokihara, Hiroshi and Miyagi, Yohei and Nakayama, Haruhiko and Matsumoto, Shingo and Tsuboi, Masahiro and Goto, Koichi and Yin, Zhihua and Shi, Jianxin and Takahashi, Atsushi and Goto, Akiteru and Minamiya, Yoshihiro and Shimizu, Kimihiro and Tanaka, Kazumi and Wu, Tangchun and Wei, Fusheng and Wong, Jason Y Y and Matsuda, Fumihiko and Su, Jian and Kim, Yeul Hong and Oh, In-Jae and Song, Fengju and Lee, Victor Ho Fun and Su, Wu-Chou and Chen, Yuh-Min and Chang, Gee-Chen and Chen, Kuan-Yu and Huang, Ming-Shyan and Yang, Pan-Chyr and Lin, Hsien-Chih and Xiang, Yong-Bing and Seow, Adeline and Park, Jae Yong and Kweon, Sun-Seog and Chen, Chien-Jen and Li, Haixin and Gao, Yu Tang and Wu, Chen and Qian, Biyun and Lu, Daru and Liu, Jianjun and Jeon, Hyo-Sung and Hsiao, Chin-Fu and Sung, Jae Sook and Tsai, Ying-Huang and Jung, Yoo Jin and Guo, Huan and Hu, Zhibin and Wang, Wen-Chang and Chung, Charles C and Lawrence, Charles and Burdett, Laurie and Yeager, Meredith and Jacobs, Kevin B and Hutchinson, Amy and ...
Human molecular genetics, ISSN 0964-6906, 01/2017, Volume 26, Issue 2, pp. 454 - 465
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by Kim, Jihun and Bowlby, Reanne and Mungall, Andrew J and Robertson, A. Gordon and Odze, Robert D and Cherniack, Andrew D and Shih, Juliann and Pedamallu, Chandra Sekhar and Cibulskis, Carrie and Dunford, Andrew and Meier, Samuel R and Kim, Jaegil and Raphael, J and Wu, Hsin-Ta and Wong, Alexandra M and Willis, Joseph E and Bass, Adam J and Derks, Sarah and Garman, Katherine and McCall, Shannon J and Wiznerowicz, MacIej and Pantazi, Angeliki and Parfenov, Michael and Thorsson, Vésteinn and Shmulevich, Ilya and Dhankani, Varsha and Miller, Michael and Sakai, Ku Leuven Ryo and Wang, Kenneth and Schultz, Nikolaus and Shen, Ronglai and Arora, Arshi and Weinhold, Nils and Sánchez-Vega, Francisco and Kelsen, David P and Zhang, Julia and Felau, Ina and Demchok, John and Rabkin, Charles S and Camargo, M. Constanza and Zenklusen, Jean Claude and Bowen, Jay and Leraas, Kristen and Lichtenberg, Tara M and Curtis, Christina and Seoane, Jose A and Ojesina, Akinyemi I and Beer, David G and Gulley, Margaret L and Pennathur, Arjun and Luketich, James D and Zhou, Zhongren and Weisenberger, Daniel J and Akbani, Rehan and Lee, Ju-Seog and Liu, Wenbin and Mills, Gordon B and Zhang, Wei and Reid, Brian J and Hinoue, Toshinori and Laird, Peter W and Shen, Hui and Piazuelo, M. Blanca and Schneider, Barbara G and McLellan, Michael and Taylor-Weiner, Amaro and Lawrence, Michael and Cibulskis, Kristian and Stewart, Chip and Getz, Gad and Lander, Eric and Gabriel, Stacey B and DIng, Li and McLellan, Michael D and Miller, Christopher A and Appelbaum, Elizabeth L and Cordes, Matthew G and Fronick, Catrina C and Fulton, Lucinda A and Mardis, Elaine R and Wilson, Richard K and Schmidt, Heather K and Fulton, Robert S and Ally, Adrian and Balasundaram, Miruna and Carlsen, Rebecca and Chuah, Eric and Dhalla, Noreen and Holt, Robert A and Jones, Steven J. M and Kasaian, Katayoon and Brooks, Denise and Li, Haiyan I and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Karen L and Schein, Jacqueline E and Sipahimalani, Payal and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Data Coordination Center: CSRA Inc and Duke University and Ribeirão Preto Medical School and Israelitisches Krankenhaus Hamburg and Project Team: National Institutes of Health and Tissue Source Sites: Analytic Biologic Services and Nationwide Children’s Hospital and Greater Poland Cancer Centre and Brown University and University of Michigan and Mayo Clinic and Broad Institute and Keimyung University School of Medicine and Asan Medical Center and Barretos Cancer Hospital and University of Alabama and Indiana University School of Medicine and Invidumed and National Cancer Center Goyang and Yonsei University College of Medicine and Vanderbilt University and University of North Carolina at Chapel Hill and Cureline and Cancer Genome Atlas Research Network and Institute of Oncology of Moldova and University of Pittsburgh School of Medicine and University of Pittsburgh and Genome Characterization Centers: BC Cancer Agency and Analysis Working Group: Asan University and University of Texas MD Anderson Cancer Center and Case Western Reserve University and National Cancer Institute and Genome Data Analysis Centers: Broad Institute and St. Joseph’s Hospital &Medical Center and University of Southern California and Institute for Systems Biology and Ontario Tumour Bank and University of Washington and University of Rochester and Harvard Medical School and KU Leuven and Genome Sequencing Center: Broad Institute and Brigham and Women’s Hospital and Memorial Sloan Kettering Cancer Center and Disease Working Group: Duke University and Erasmus University and Christiana Care Health System and University of Kansas Medical Center and Research Institute at Nationwide Children’s Hospital and International Genomics Consortium and Tayside Tissue Bank and Peter MacCallum Cancer Centre and Pusan National University Medical School and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University and BioreclamationIVT and Dana-Farber Cancer Institute and University of Southern California Epigenome Center and Stanford University and BC Cancer Agency and Chonnam National University Medical School and St. Petersburg Academic University and University of North Carolina and University of Dundee and Van Andel Research Institute and Washington University in St. Louis and Emory University and Washington University and University of California Santa Cruz and Biospecimen Core Resource: International Genomics Consortium and Asterand Bioscience and Botkin Municipal Clinic
Nature (London), ISSN 1476-4687, 2017, Volume 541, Issue 7636, pp. 169 - 175
Journal Article
by Machiela, Mitchell J and Hsiung, Chao Agnes and Shu, Xiao-Ou and Seow, Wei Jie and Wang, Zhaoming and Matsuo, Keitaro and Hong, Yun-Chul and Seow, Adeline and Wu, Chen and Hosgood, H Dean and Chen, Kexin and Wang, Jiu-Cun and Wen, Wanqing and Cawthon, Richard and Chatterjee, Nilanjan and Hu, Wei and Caporaso, Neil E and Park, Jae Yong and Chen, Chien-Jen and Kim, Yeul Hong and Kim, Young Tae and Landi, Maria Teresa and Shen, Hongbing and Lawrence, Charles and Burdett, Laurie and Yeager, Meredith and Chang, I-Shou and Mitsudomi, Tetsuya and Kim, Hee Nam and Chang, Gee-Chen and Bassig, Bryan A and Tucker, Margaret and Wei, Fusheng and Yin, Zhihua and An, She-Juan and Qian, Biyun and Lee, Victor Ho Fun and Lu, Daru and Liu, Jianjun and Jeon, Hyo-Sung and Hsiao, Chin-Fu and Sung, Jae Sook and Kim, Jin Hee and Gao, Yu-Tang and Tsai, Ying-Huang and Jung, Yoo Jin and Guo, Huan and Hu, Zhibin and Hutchinson, Amy and Wang, Wen-Chang and Klein, Robert J and Chung, Charles C and Oh, In-Jae and Chen, Kuan-Yu and Berndt, Sonja I and Wu, Wei and Chang, Jiang and Zhang, Xu-Chao and Huang, Ming-Shyan and Zheng, Hong and Wang, Junwen and Zhao, Xueying and Li, Yuqing and Choi, Jin Eun and Su, Wu-Chou and Park, Kyong Hwa and Sung, Sook Whan and Chen, Yuh-Min and Liu, Li and Kang, Chang Hyun and Hu, Lingmin and Chen, Chung-Hsing and Pao, William and Kim, Young-Chul and Yang, Tsung-Ying and Xu, Jun and Guan, Peng and Tan, Wen and Su, Jian and Wang, Chih-Liang and Li, Haixin and Sihoe, Alan Dart Loon and Zhao, Zhenhong and Chen, Ying and Choi, Yi Young and Hung, Jen-Yu and Kim, Jun Suk and Yoon, Ho-Il and Cai, Qiuyin and Lin, Chien-Chung and Park, In Kyu and Xu, Ping and Dong, Jing and Kim, Christopher and He, Qincheng and Perng, Reury-Perng and Kohno, Takashi and Kweon, Sun-Seog and Chen, Chih-Yi and Vermeulen, Roel C H and ...
International journal of cancer, ISSN 0020-7136, 07/2015, Volume 137, Issue 2, pp. 311 - 319
Journal Article
by Bell, D and Berchuck, A and Birrer, M and Chien, J and Cramer, D.W and Dao, F and Dhir, R and Disaia, P and Gabra, H and Glenn, P and Godwin, A.K and Gross, J and Hartmann, L and Huang, M and Huntsman, D.G and Iacocca, M and Imielinski, M and Kalloger, S and Karlan, B.Y and Levine, D.A and Mills, G.B and Morrison, C and Mutch, D and Olvera, N and Orsulic, S and Park, K and Petrelli, N and Rabeno, B and Rader, J.S and Sikic, B.I and Smith-Mccune, K and Sood, A.K and Bowtell, D and Penny, R and Testa, J.R and Chang, K and Dinh, H.H and Drummond, J.A and Fowler, G and Gunaratne, P and Hawes, A.C and Kovar, C.L and Lewis, L.R and Morgan, M.B and Newsham, I.F and Santibanez, J and Reid, J.G and Trevino, L.R and Wu, Y.-Q and Wang, M and Muzny, D.M and Wheeler, D.A and Gibbs, R.A and Getz, G and Lawrence, M.S and Cibulskis, K and Sivachenko, A.Y and Sougnez, C and Voet, D and Wilkinson, J and Bloom, T and Ardlie, K and Fennell, T and Baldwin, J and Gabriel, S and Lander, E.S and Ding, L and Fulton, R.S and Koboldt, D.C and McLellan, M.D and Wylie, T and Walker, J and O'Laughlin, M and Dooling, D.J and Fulton, L and Abbott, R and Dees, N.D and Zhang, Q and Kandoth, C and Wendl, M and Schierding, W and Shen, D and Harris, C.C and Schmidt, H and Kalicki, J and Delehaunty, K.D and Fronick, C.C and Demeter, R and Cook, L and Wallis, J.W and Lin, L and Magrini, V.J and Hodges, J.S and Eldred, J.M and Smith, S.M and Pohl, C.S and Vandin, F and Raphael, B.J and Weinstock, G.M and Mardis, E.R and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Nature (London), ISSN 1476-4687, 2011, Volume 474, Issue 7353, pp. 609 - 615
Journal Article