X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (134) 134
Patent (119) 119
Publication (6) 6
Dissertation (4) 4
Book Chapter (1) 1
Conference Proceeding (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
chemistry (117) 117
metallurgy (114) 114
organic chemistry (112) 112
peptides (95) 95
human necessities (82) 82
hygiene (82) 82
medical or veterinary science (82) 82
preparations for medical, dental, or toilet purposes (79) 79
biochemistry (76) 76
enzymology (74) 74
microbiology (74) 74
beer (73) 73
mutation or genetic engineering (73) 73
spirits (73) 73
vinegar (73) 73
wine (73) 73
compositions thereof (65) 65
culture media (65) 65
microorganisms or enzymes (65) 65
propagating, preserving or maintaining microorganisms (65) 65
physics (61) 61
investigating or analysing materials by determining theirchemical or physical properties (58) 58
measuring (58) 58
testing (58) 58
humans (46) 46
specific therapeutic activity of chemical compounds ormedicinal preparations (41) 41
animals (29) 29
index medicus (29) 29
biochemistry & molecular biology (25) 25
compositions or test papers therefor (24) 24
condition-responsive control in microbiological orenzymological processes (24) 24
measuring or testing processes involving enzymes, nucleicacids or microorganisms (24) 24
processes of preparing such compositions (24) 24
fermentation or enzyme-using processes to synthesise a desiredchemical compound or composition or to separate optical isomersfrom a racemic mixture (22) 22
heterocyclic compounds (16) 16
mice (16) 16
signal transduction (15) 15
amino acid sequence (13) 13
cell line (13) 13
immunology (13) 13
phosphorylation (13) 13
activation (12) 12
agriculture (12) 12
molecular sequence data (12) 12
protein binding (12) 12
animal husbandry (11) 11
calculating (11) 11
cells, cultured (11) 11
computing (11) 11
counting (11) 11
electric digital data processing (11) 11
fishing (11) 11
forestry (11) 11
hunting (11) 11
inflammation (11) 11
trapping (11) 11
care of birds, fishes, insects (10) 10
map kinase kinase kinases - antagonists & inhibitors (10) 10
new breeds of animals (10) 10
rearing or breeding animals, not otherwise provided for (10) 10
structure-activity relationship (10) 10
combinatorial chemistry (9) 9
information and communication technology [ict] specially adaptedfor specific application fields (9) 9
libraries, e.g. chemical libraries, in silicolibraries (9) 9
models, molecular (9) 9
rheumatoid-arthritis (9) 9
tumor necrosis factor-alpha - biosynthesis (9) 9
chemistry, medicinal (8) 8
climate change mitigation technologies in the production orprocessing of goods (8) 8
female (8) 8
general tagging of cross-sectional technologies spanning over several sections of the ipc (8) 8
general tagging of new technological developments (8) 8
lipopolysaccharides - pharmacology (8) 8
map kinase kinase kinases - metabolism (8) 8
nf-kappa-b (8) 8
phospholipases a2 (8) 8
proto-oncogene proteins - antagonists & inhibitors (8) 8
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (8) 8
technologies or applications for mitigation or adaptation againstclimate change (8) 8
tumor-necrosis-factor (8) 8
binding sites (7) 7
cell biology (7) 7
chemistry, organic (7) 7
death domain (7) 7
enzyme activation (7) 7
nf-kappa b - metabolism (7) 7
phospholipases a - metabolism (7) 7
recombinant proteins - metabolism (7) 7
research (7) 7
arthritis, rheumatoid - drug therapy (6) 6
cytosol - enzymology (6) 6
derivatives thereof (6) 6
disease (6) 6
enzyme inhibitors - pharmacology (6) 6
gene expression (6) 6
identification (6) 6
male (6) 6
nucleic acids (6) 6
nucleosides (6) 6
nucleotides (6) 6
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Annals of the Rheumatic Diseases, ISSN 0003-4967, 02/2016, Volume 75, Issue 2, pp. 422 - 429
ObjectiveTo investigate the effects of BET bromodomain protein inhibition on inflammatory activation and functional properties of rheumatoid arthritis synovial... 
EPIGENETICS | ACTIVATION | SECUKINUMAB | CHROMATIN | DOUBLE-BLIND | ANTI-INTERLEUKIN-17A MONOCLONAL-ANTIBODY | RHEUMATOLOGY | BET PROTEIN | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Gene Expression - drug effects | Humans | Lipopolysaccharides - metabolism | Arthritis, Rheumatoid - enzymology | Matrix Metalloproteinase 3 - metabolism | Nuclear Proteins - metabolism | RNA, Messenger - metabolism | Synovial Membrane - metabolism | Heterocyclic Compounds, 4 or More Rings - pharmacology | Osteoarthritis - genetics | Osteoarthritis - enzymology | Transcription Factors - metabolism | Arthritis, Rheumatoid - genetics | Interleukin-1beta - metabolism | Interleukin-8 - metabolism | Toll-Like Receptors - metabolism | Matrix Metalloproteinase 1 - metabolism | Interleukin-6 - metabolism | Protein-Serine-Threonine Kinases - metabolism | RNA-Binding Proteins - metabolism | Fibroblasts - metabolism | Epigenetic inheritance | Care and treatment | Interleukins | Tumor necrosis factor | Rheumatoid arthritis | Dosage and administration | Research | Enzymes | Immunoglobulins | Statistical analysis | Disease | Cytokines | Laboratories | Gene expression | Variance analysis | Bone surgery | Studies | Proteins | Pathology | Rodents | DNA methylation | Epigenetics | Fibroblasts | Tumor necrosis factor-TNF | Chemokines | Deoxyribonucleic acid--DNA
Journal Article
Journal of Immunology, ISSN 0022-1767, 09/2016, Volume 197, Issue 6, pp. 2421 - 2433
Journal Article
European Journal of Plant Pathology, ISSN 0929-1873, 6/2015, Volume 142, Issue 2, pp. 331 - 343
Oncidium orchids are important ornamental flowers for export in Taiwan, but their production is limited by bacterial soft rot disease. The common pathogens of... 
Life Sciences | Plant Pathology | Reactive oxygen species | Temperature | Life Sciences, general | Pectobacterium spp | Ecology | Agriculture | Plant immune system | Oncidium orchid | Plant Sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 45, pp. 18689 - 18698
Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a critical role in innate immune signaling by Toll-like receptors (TLRs), and loss of IRAK4 activity... 
cytokine | GENE-EXPRESSION SIGNATURE | INTERLEUKIN-1 | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | IKK | IKK-BETA | PERIPHERAL-BLOOD | NFB | IRAK4 | INDUCTION | LUPUS | TAK1 | inflammation | interferon regulatory factor | IRF5 | TLR | NF-KAPPA-B | Toll-like receptor | Interleukin-1 Receptor-Associated Kinases - metabolism | Monocytes - cytology | Humans | Interferon Regulatory Factors - metabolism | Monocytes - metabolism | NF-kappa B - metabolism | Monocytes - immunology | MAP Kinase Kinase Kinases - chemistry | I-kappa B Kinase - metabolism | Protein Processing, Post-Translational - drug effects | I-kappa B Kinase - antagonists & inhibitors | Interferon Regulatory Factors - agonists | Phosphorylation - drug effects | MAP Kinase Kinase Kinases - antagonists & inhibitors | Single-Cell Analysis | Cytokines - genetics | Toll-Like Receptor 8 - agonists | Toll-Like Receptor 7 - agonists | Toll-Like Receptor 7 - metabolism | Cytokines - metabolism | NF-kappa B p50 Subunit - metabolism | Cytokines - agonists | Cells, Cultured | Computational Biology | MAP Kinase Kinase Kinases - metabolism | Enzyme Activation - drug effects | Gene Expression Regulation - drug effects | Monocytes - drug effects | Models, Immunological | Animals | Active Transport, Cell Nucleus - drug effects | Interleukin-1 Receptor-Associated Kinases - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | I-kappa B Kinase - chemistry | Toll-Like Receptor 8 - metabolism | Signal Transduction | NFκB | IKKβ
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2017, Volume 60, Issue 13, pp. 5521 - 5542
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 7624 - 8
Obese ZSF1 rats exhibit spontaneous time-dependent diabetic nephropathy and are considered to be a highly relevant animal model of progressive human diabetic... 
EPB41L5 | IL-33 | LONGEVITY GENE | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | Alternative splicing | Immune response | Diabetes mellitus | Data processing | Ribonucleic acid--RNA | Gene expression | Cell interactions | Signal transduction | Nephropathy | Rodents | Computer applications | Cell adhesion | Cytoskeleton | Diabetes
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2014, Volume 289, Issue 15, pp. 10865 - 10875
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, p. e0184843
Cyclic GMP-AMP synthase (cGAS) initiates the innate immune system in response to cytosolic dsDNA. After binding and activation from dsDNA, cGAS uses ATP and... 
2ND-MESSENGER | SYNTHASE | CYCLIC GMP-AMP | AICARDI-GOUTIERES-SYNDROME | GENE | MECHANISM | MULTIDISCIPLINARY SCIENCES | CYTOSOLIC DNA SENSOR | STING PATHWAY | MUTATIONS | EXONUCLEASE TREX1 | Antibodies - metabolism | Enzyme-Linked Immunosorbent Assay | Pyrazoles - chemical synthesis | Pyrimidines - chemical synthesis | Humans | Enzyme Inhibitors - pharmacology | Models, Molecular | Pyrimidines - pharmacology | Enzyme Inhibitors - chemical synthesis | Drug Discovery | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Mass Spectrometry | Protein Binding | Nucleotidyltransferases - antagonists & inhibitors | Molecular Structure | Nucleotidyltransferases - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Fluorescence Polarization | Nucleotides, Cyclic - immunology | Pyrazoles - pharmacology | Care and treatment | Physiological aspects | Development and progression | Genetic aspects | Cyclic adenylic acid | Research | Autoimmune diseases | Polarization | GTP | Disease | Genes | Fluorescence | Assaying | Optimization | Proteins | Immunology | Systemic lupus erythematosus | Cyclic GMP | Chemical bonds | Polarity | Sensors | Deoxyribonucleic acid--DNA | Immune system | Lupus | Fluorescence polarization | Immune response | AMP | Cystic fibrosis | Medical screening | Medicine | Chronic conditions | Phosphodiester bonds | Inhibitors | Monoclonal antibodies | Affinity | Interferon | ATP | Binding sites | BASIC BIOLOGICAL SCIENCES | Deoxyribonucleic acid | DNA
Journal Article
Journal Article