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Applied catalysis. B, Environmental, ISSN 0926-3373, 2015, Volume 165, pp. 572 - 578
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2014, Volume 24, Issue 6, pp. 742 - 761
... ,Yuhan Chen ,Tao Li ,Ping Xie ,Lin Yuan ,Lei Song。,Lanzhi M a ,Lujing Ding ,Fuchu He ,Lingqiang Zhang ,State Key Laboratory ofProteomics,Beo'ing Proteome... 
细胞周期蛋白D | 酪蛋白激酶 | 巨噬细胞集落刺激因子 | 激活 | 介导 | Akt | 细胞增殖 | 小鼠巨噬细胞 | GSK3β | Akt signaling | CKIP-1 | macrophage proliferation | TRAF6 | FACTOR-1 RECEPTOR | DOMAIN-CONTAINING PROTEIN | UBIQUITIN LIGASE | KINASE 2-INTERACTING PROTEIN-1 | STIMULATING FACTOR-I | CELL BIOLOGY | SIGNAL-TRANSDUCTION | DENDRITIC CELL SUBTYPES | DEFECTIVE INTERLEUKIN-1 | GSK3 beta | DIFFERENTIATION | NF-KAPPA-B | Phosphorylation | Cell Proliferation | Apoptosis - drug effects | Humans | Glycogen Synthase Kinase 3 beta | TNF Receptor-Associated Factor 6 - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - metabolism | Macrophage Colony-Stimulating Factor - pharmacology | TNF Receptor-Associated Factor 6 - genetics | Proto-Oncogene Proteins c-akt - metabolism | Signal Transduction | Bone Marrow Cells - cytology | Mice, Inbred C57BL | Cells, Cultured | Macrophages - cytology | Glycogen Synthase Kinase 3 - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Mice, Knockout | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | TNF Receptor-Associated Factor 6 - metabolism | Mice | Proto-Oncogene Proteins c-myc - genetics | Cyclin D - genetics | Cyclin D - metabolism | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Original
Journal Article
Journal of cellular and molecular medicine, ISSN 1582-1838, 2017, Volume 21, Issue 12, pp. 3347 - 3359
This study was aimed to explore the role of miR‐29b‐3p and PGRN in chondrocyte apoptosis and the initiation and progress of osteoarthritis (OA). Both... 
MiR‐29b‐3p | Progranulin | Chondrocyte | Osteoarthritis | MiR-29b-3p | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | PROLIFERATION | GRANULIN-EPITHELIN PRECURSOR | MODEL | CARTILAGE DEGRADATION | DEGENERATION | CELL BIOLOGY | BINDS | ARTICULAR-CARTILAGE | GROWTH-FACTOR | MICRORNA | RNA, Small Interfering - genetics | Luciferases - metabolism | MicroRNAs - antagonists & inhibitors | Humans | Middle Aged | Apoptosis - genetics | Male | MicroRNAs - metabolism | Luciferases - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Oligoribonucleotides - metabolism | Cartilage, Articular - metabolism | Base Sequence | Female | Osteoarthritis - pathology | Chondrocytes - metabolism | Genes, Reporter | Chondrocytes - pathology | Progranulins | Signal Transduction | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Osteoarthritis - metabolism | Rats | Osteoarthritis - genetics | Cartilage, Articular - pathology | Animals | Cell Line, Tumor | Aged | MicroRNAs - genetics | Primary Cell Culture | Antagomirs - metabolism | Antagomirs - genetics | Oligoribonucleotides - genetics | RNA, Small Interfering - metabolism | RNA | Apoptosis | Cell proliferation | Knee | Chondrosarcoma | Secretion | Wounds | Arthritis | mRNA | Injection | Chromosome 3 | Cartilage | Biomedical materials | Reporter gene | Transfection | Surgery | Chondrocytes | Biocompatibility | Degeneration | Inhibition | Recombinant | Cartilage diseases | Original
Journal Article
Journal Article
Seminars in cancer biology, ISSN 1044-579X, 2019
Smad ubiquitination regulatory factor 1 (Smurf1) and Smurf2 are HECT-type E3 ubiquitin ligases, and both Smurfs were initially identified to regulate Smad... 
Ubiquitination | Smurf2 | E3 ligase | Smurf1 | Cancer
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2012, Volume 22, Issue 8, pp. 1285 - 1303
... Yin ,Chunyan Tian 一,Fuchu He ,一.Lingqiang Zhang。,。Department of Medical Genetics,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences&Peking... 
烷化剂 | N-甲基 | 酶抑制 | p53基因突变 | 细胞周期阻滞 | DNA结合结构域 | 糖基化 | 敏感性 | base excision repair | alkylating agents | cell cycle arrest | MPG | p53 | METHYLATING AGENTS | PROTEIN | COMET ASSAY | MICROSATELLITE INSTABILITY | MECHANISMS | DAMAGE | CELL BIOLOGY | BASE EXCISION-REPAIR | GENES | CHRONIC INFLAMMATION | BINDING | Humans | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Substrate Specificity | Antineoplastic Agents, Alkylating - pharmacology | Tumor Suppressor Protein p53 - genetics | Transfection | MCF-7 Cells | Dacarbazine - pharmacology | Dacarbazine - analogs & derivatives | Cell Cycle Proteins - genetics | DNA Breaks | Nuclear Proteins - genetics | DNA Glycosylases - metabolism | Protein Structure, Tertiary | Cell Survival | HCT116 Cells | Cell Cycle Proteins - metabolism | DNA Glycosylases - genetics | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | Comet Assay | Protein Interaction Mapping | Gene Expression Regulation, Enzymologic | Point Mutation | Cell Cycle Checkpoints | DNA Repair | Protein Binding | Fluorouracil - pharmacology | Methyl Methanesulfonate - pharmacology | Drug Screening Assays, Antitumor | Drugs | Enzymes | Tumor cells | Alkylating agents | Lung | DNA glycosylase | DNA repair | Alkylation | Stress | p53 protein | 14-3-3 protein | Colon cancer | Cell cycle | GADD45 protein | Tumor suppressor genes | Apoptosis | Original
Journal Article
Journal Article
Advances in experimental medicine and biology, ISSN 0065-2598, 2020, Volume 1217, p. 79
Stem cells can remain quiescent, self-renewal, and differentiate into many types of cells and even cancer stem cells. The coordination of these complex... 
Ubiquitination | Animals | Neoplastic Stem Cells - metabolism | Humans | Cullin Proteins - metabolism | Neoplastic Stem Cells - pathology | Stem Cells - cytology | Proteasome Endopeptidase Complex - metabolism | Stem Cells - metabolism
Journal Article
Journal Article