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ACS Chemical Neuroscience, ISSN 1948-7193, 07/2018, Volume 9, Issue 7, pp. 1517 - 1517
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 09/2016, Volume 7, Issue 9, pp. 1174 - 1174
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 11/2017, Volume 8, Issue 11, pp. 2349 - 2349
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 08/2017, Volume 8, Issue 8, pp. 1633 - 1634
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 03/2019, Volume 10, Issue 3, pp. 1115 - 1115
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2019, Volume 144, pp. 19 - 28
Stress can precipitate or worsen symptoms of many psychiatric illnesses. Dysregulation of the prefrontal cortex (PFC) glutamate system may underlie these... 
mGlu3 | mGlu5 | Reversal learning | Stress | Synaptic plasticity | Prelimbic prefrontal cortex | reversal learning | stress | synaptic plasticity | prelimbic prefrontal cortex
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 09/2017, Volume 8, Issue 9, pp. 1813 - 1813
Journal Article
Neuropharmacology, ISSN 0028-3908, 05/2017, Volume 118, p. 209
The dorsolateral striatum is critically involved in movement control and motor learning. Striatal function is regulated by a variety of neuromodulators... 
Neurosciences | Acetylcholine | Drug discovery | Neurons | GABA
Journal Article
Biological Psychiatry, ISSN 0006-3223, 06/2019, Volume 85, Issue 12, pp. 989 - 1000
Background: The prefrontal cortex (PFC) integrates information from multiple inputs to exert top-down control allowing for appropriate responses in a given... 
Fear extinction | Positive allosteric modulator | Posttraumatic stress disorder | Prefrontal cortex | muscarinic receptor | Synaptic plasticity
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 03/2018, Volume 9, Issue 3, pp. 391 - 391
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 12/2017, Volume 8, Issue 12, pp. 2570 - 2572
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 05/2019, Volume 29, Issue 10, pp. 1211 - 1214
This letter describes a diversity-oriented library approach to rapidly assess diverse heterocycles as bioisosteric replacements for a metabolically labile... 
Negative allosteric modulator (NAM) | Structure-activity relationship (SAR) | mGlu7 | VU6019278 | Metabotropic glutamate receptor
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 05/2019, Volume 29, Issue 10, p. 1211
This letter describes a diversity-oriented library approach to rapidly assess diverse heterocycles as bioisosteric replacements for a metabolically labile... 
Surveys | Medical colleges | Neurosciences | Lubrication and lubricants | Drug discovery | Glutamate | Blood proteins | Protein binding
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 05/2019, Volume 29, Issue 10, pp. 1211 - 1214
This letter describes a diversity-oriented library approach to rapidly assess diverse heterocycles as bioisosteric replacements for a metabolically labile... 
mGlu | Negative allosteric modulator (NAM) | Structure-activity relationship (SAR) | VU6019278 | Metabotropic glutamate receptor
Journal Article
ACS chemical neuroscience, ISSN 1948-7193, 07/2019
Gamma-hydroxybutyrate (GHB) is a naturally occurring short-chain fatty acid that rose to prominence as a popular club drug in the 1990s. Originally developed... 
Index Medicus
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2019, Volume 29, Issue 18, pp. 2670 - 2674
This letter describes the further optimization of a series of mGlu NAMs based on an -aryl phenoxyethoxy pyridinone core. A multidimensional optimization... 
mGlu3 | Negative allosteric modulator (NAM) | Structure-Activity Relationship (SAR) | Metabotropic glutamate receptor
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2019, Volume 29, Issue 18, p. 2670
This letter describes the further optimization of a series of mGlu.sub.3 NAMs based on an N-aryl phenoxyethoxy pyridinone core. A multidimensional optimization... 
Medical colleges | Neurosciences | Antidepressants | Drug discovery | G proteins | Glutamate | Antianxiety agents
Journal Article
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