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Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2019, Volume 29, Issue 18, p. 2670
This letter describes the further optimization of a series of mGlu.sub.3 NAMs based on an N-aryl phenoxyethoxy pyridinone core. A multidimensional optimization... 
Medical colleges | Neurosciences | Antidepressants | Drug discovery | G proteins | Glutamate | Antianxiety agents
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 07/2018, Volume 9, Issue 7, pp. 1520 - 1529
After the identification of the influence of serotonergic receptors in ameliorating the negative symptoms associated with schizophrenia, atypical... 
serotonin | histamine | atypical | adrenergic | Risperdal | schizophrenia | 5-HT | Risperidone | dopamine | CHEMISTRY, MEDICINAL | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | D-2 | RECEPTOR OCCUPANCY | NEUROSCIENCES | ATYPICAL ANTIPSYCHOTICS | P-GLYCOPROTEIN | PHARMACOKINETICS | DRUGS | PHARMACOGENETICS | DOPAMINE HYPOTHESIS | BINDING | 5-HT2A
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Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 03/2019, Volume 10, Issue 3, pp. 1025 - 1034
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Journal Article
Science Signaling, ISSN 1945-0877, 12/2019, Volume 12, Issue 610, p. eaax2057
Highly selective, positive allosteric modulators (PAMs) of the M1 subtype of muscarinic acetylcholine receptor have emerged as an exciting new approach to... 
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2019, Volume 144, p. 19
Stress can precipitate or worsen symptoms of many psychiatric illnesses. Dysregulation of the prefrontal cortex (PFC) glutamate system may underlie these... 
Neurosciences | Synthesis | Glycogen | Physiological aspects | Glutamate | Mental illness
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2014, Volume 57, Issue 18, pp. 7485 - 7498
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2019, Volume 15, Issue 7, pp. P574 - P574
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Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2019, Volume 15, Issue 7, pp. P253 - P253
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 11/2017, Volume 8, Issue 11, pp. 2348 - 2348
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