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Neurobiology of Disease, ISSN 0969-9961, 12/2019, Volume 132, p. 104514
TAR-DNA binding protein 43 (TDP-43) is a multifunctional RNA binding protein directly implicated in the etiology of amyotrophic lateral sclerosis (ALS).... 
Amyotrophic lateral sclerosis | Protein kinase R | TDP-43 | Reactive astrocytes
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 11, p. 2734
Stress granules are higher order assemblies of nontranslating mRNAs and proteins that form when translation initiation is inhibited. Stress granules are... 
Stresses | Self assembly | Yeast | RNA-protein interactions | Neurodegenerative diseases | Translation initiation | Ribonucleic acid--RNA | Gene expression | Cells | Proteins | Neurological diseases | RNA-binding protein | Self-assembly | Granular materials | Granules | Assemblies | Protein interaction | Neurological disorders
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 04/2019, Volume 116, Issue 18, p. 8895
Alzheimer's disease (AD) is characterized by the deposition of p-sheet-rich, insoluble amyloid p-peptide (Ap) plaques; however, plaque burden is not correlated... 
Physiological aspects | Development and progression | Structure | Alzheimer's disease | Amyloid beta-protein
Journal Article
Science, ISSN 0036-8075, 2/2012, Volume 335, Issue 6071, pp. 926 - 927
A number of eukaryotic proteins contain stretches of repeating glutamine residues . For example, huntingtin pro- tein contains a glutamine-repeat sequence of 6... 
Killing | Aggregation | Protein isoforms | Neurodegenerative diseases | Cell death | Neurons | Male animals | PERSPECTIVES | Death | Gonads | Apoptosis | MULTIDISCIPLINARY SCIENCES | Proteins | Nematodes | Neurotransmitters | Neurological disorders
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 02/2015, Volume 36, Issue 2, p. 857
Multiple gene expression alterations have been linked to Alzheimer's disease (AD), implicating multiple metabolic pathways in its pathogenesis. However, a... 
Proteins | Behavior genetics | Analysis | Therapeutics | Gene expression | Nematoda | Alzheimer's disease | Homeopathy | Materia medica and therapeutics
Journal Article
Journal of experimental neuroscience, ISSN 1179-0695, 2019, Volume 13, p. 1179069519830697
Changes in chromatin and epigenetic modifications have been associated with aging and aging-associated neurodegenerative diseases, although the causal... 
Journal Article
Journal Article
Acta Neuropathologica Communications, ISSN 2051-5960, 11/2018, Volume 6, Issue 1
Exposure to the [beta]-amyloid peptide (A[beta]) is toxic to neurons and other cell types, but the mechanism(s) involved are still unresolved. Synthetic... 
Oligomers | Care and treatment | Neurons | Research | Alzheimer's disease
Journal Article
Journal of Visualized Experiments, ISSN 1940-087X, 2010, Issue 44
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2016, Volume 19, Issue 5, pp. 668 - 677
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2010, Volume 362, Issue 7, pp. 600 - 613
Journal Article
Nature Neuroscience, ISSN 1097-6256, 08/2015, Volume 18, Issue 8, pp. 1175 - 1182
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2013, Volume 110, Issue 12, p. 4853
Journal Article
Genetics, ISSN 0016-6731, 11/2010, Volume 186, Issue 3, p. 857
  Epidemiological studies have reported that coffee and/or caffeine consumption may reduce Alzheimer's disease (AD) risk. We found that coffee extracts can... 
Care and treatment | Usage | Amyloid beta-protein | Causes of | Genetic aspects | Research | Gene expression | Alzheimer's disease | Health aspects | Caffeine | Materia medica, Vegetable | Plant extracts | Studies | Brain | Coffeehouses | E coli | Worms
Journal Article
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