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Circulation, ISSN 0009-7322, 05/2017, Volume 135, Issue 19, pp. 1832 - 1847
Journal Article
by Northcott, Paul A and Lee, Catherine and Zichner, Thomas and Stütz, Aian M and Erkek, Serap and Kawauchi, Daisuke and Shih, David J. H and Hovestadt, Volker and Zapatka, Marc and Sturm, Dominik and Jones, David T. W and Kool, Marcel and Remke, Marc and Cavalli, Florence M. G and Zuyderduyn, Scott and Bader, Gary D and VandenBerg, Scott and Esparza, Lourdes Aiana and Ryzhova, Marina and Wang, Wei and Wittmann, Anea and Stark, Sebastian and Sieber, Laura and Seker-Cin, Huriye and Linke, Linda and Kratochwil, Fabian and Jäger, Natalie and Buchhalter, Ivo and Imbusch, Charles D and Zipprich, Gideon and Raeder, Benjamin and Schmidt, Sabine and Diessl, Nicolle and Wolf, Stephan and Wiemann, Stefan and Brors, Benedikt and Lawerenz, Chris and Eils, Jürgen and Warnatz, Hans-Jörg and Risch, Thomas and Yaspo, Marie-Laure and Weber, Ursula D and Bartholomae, Cynthia C and von Kalle, Christof and Turányi, Eszter and Hauser, Peter and Sanden, Emma and Darabi, Anna and Siesjö, Peter and Sterba, Jaroslav and Zitterbart, Karel and Sumerauer, David and van Sluis, Peter and Versteeg, Rogier and Volckmann, Richard and Koster, Jan and Schuhmann, Martin U and Ebinger, Martin and Grimes, H. Leighton and Robinson, Giles W and Gajjar, Amar and Mynarek, Martin and von Hoff, Katja and Rutkowski, Stefan and Pietsch, Torsten and Scheurlen, Wolfram and Felsberg, Jörg and Reifenberger, Guido and Kulozik, Aneas E and von Deimling, Aneas and Witt, Olaf and Eils, Roland and Gilbertson, Richard J and Korshunov, Aney and Taylor, Michael D and Lichter, Peter and Korbel, Jan O and Wechsler-Reya, Robert J and Pfister, Stefan M and Neurosurgery and Neurokirurgi and Lund University and BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation and Lunds universitet
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7510, pp. 428 - 434
Journal Article
by Kool, Marcel and Jones, David T.W and Jäger, Natalie and Northcott, Paul A and Pugh, Trevor J and Hovestadt, Volker and Piro, Rosario M and Esparza, L. Adriana and Markant, Shirley L and Remke, Marc and Milde, Till and Bourdeaut, Franck and Ryzhova, Marina and Sturm, Dominik and Pfaff, Elke and Stark, Sebastian and Hutter, Sonja and Şeker-Cin, Huriye and Johann, Pascal and Bender, Sebastian and Schmidt, Christin and Schmidt, Sabine and Rausch, Tobias and Shih, David and Reimand, Jüri and Sieber, Laura and Wittmann, Andrea and Linke, Linda and Witt, Olaf and Witt, Hendrik and Weber, Ursula D and Zapatka, Marc and König, Rainer and Beroukhim, Rameen and Bergthold, Guillaume and van Sluis, Peter and Volckmann, Richard and Koster, Jan and Versteeg, Rogier and Wolf, Stephan and Lawerenz, Chris and Bartholomae, Cynthia C and von Kalle, Christof and Unterberg, Andreas and Herold-Mende, Christel and Hofer, Silvia and Kulozik, Andreas E and von Deimling, Andreas and Scheurlen, Wolfram and Felsberg, Jörg and Reifenberger, Guido and Hasselblatt, Martin and Crawford, John R and Grant, Gerald A and Jabado, Nada and Perry, Arie and Cowdrey, Cynthia and Croul, Sydney and Zadeh, Gelareh and Korbel, Jan O and Doz, Francois and Delattre, Olivier and Bader, Gary D and McCabe, Martin G and Collins, V. Peter and Kieran, Mark W and Cho, Yoon-Jae and Pomeroy, Scott L and Brors, Benedikt and Taylor, Michael D and Schüller, Ulrich and Korshunov, Andrey and Eils, Roland and Wechsler-Reya, Robert J and Lichter, Peter and Pfister, Stefan M and ICGC PedBrain Tumor Project
Cancer Cell, ISSN 1535-6108, 03/2014, Volume 25, Issue 3, pp. 393 - 405
Smoothened (SMO) inhibitors recently entered clinical trials for sonic-hedgehog-driven medulloblastoma (SHH-MB). Clinical response is highly variable. To... 
NERVOUS-SYSTEM | TERT PROMOTER MUTATIONS | ONCOLOGY | GROWTH | HEDGEHOG PATHWAY INHIBITOR | ITRACONAZOLE | PEDIATRIC MEDULLOBLASTOMA | CANCER | TUMORS | MOUSE MODELS | ADULT | CELL BIOLOGY | Neoplasm Transplantation | Oncogene Proteins - genetics | Humans | Zinc Finger Protein Gli2 | Child, Preschool | Molecular Sequence Data | Infant | Male | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Biphenyl Compounds - therapeutic use | Promoter Regions, Genetic - genetics | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Young Adult | Telomerase - genetics | Hedgehog Proteins - genetics | Base Sequence | Smoothened Receptor | Adult | Female | N-Myc Proto-Oncogene Protein | Patched Receptors | Medulloblastoma - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Child | Pyridines - therapeutic use | Cerebellar Neoplasms - drug therapy | Repressor Proteins - genetics | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Cerebellar Neoplasms - genetics | Mice, SCID | Phosphatidylinositol 3-Kinases - genetics | DEAD-box RNA Helicases - genetics | Drug Resistance, Neoplasm - genetics | Animals | Adolescent | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice, Inbred NOD | High-Throughput Nucleotide Sequencing | Mice | Receptors, G-Protein-Coupled - genetics | Medulloblastoma - drug therapy | Kruppel-Like Transcription Factors - genetics | Patched-1 Receptor | Receptors, Cell Surface - genetics | Genetic aspects | Nucleotide sequencing | Analysis | Medulloblastoma | Genomics | DNA sequencing | Index Medicus
Journal Article
Neuropharmacology, ISSN 0028-3908, 10/2018, Volume 141, pp. 98 - 112
Haplotypes of the gene encoding the α2-subunit of the GABA receptor (GABA R) are associated with drug abuse, suggesting that α2-GABA Rs may play an important... 
Early-life stress | Nucleus accumbens | Early-life adversity | Cocaine | GABAA receptors | GABA | receptors | Index Medicus
Journal Article
Neuropharmacology, ISSN 0028-3908, 10/2018, Volume 141, p. 98
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.neuropharm.2018.08.021... 
Drug abuse | Analysis | Cocaine | Stress (Psychology)
Journal Article
Applied Mathematics and Computation, ISSN 0096-3003, 08/2014, Volume 241, pp. 222 - 232
Empirical time series are subject to observational noise. Naïve approaches that estimate parameters in stochastic models for such time series are likely to... 
Parameter estimation | Expectation–maximization algorithm | State-space model | Kalman filter | Expectation-maximization algorithm | MATHEMATICS, APPLIED | MAXIMUM-LIKELIHOOD | SYSTEMS | Analysis | Models | Algorithms | Maximization | State space models | Computation | Noise | Time series | Mathematical models | Estimates
Journal Article
Kidney International, ISSN 0085-2538, 04/2019, Volume 95, Issue 4, pp. 973 - 982
The safety and efficacy of spironolactone is uncertain in end-stage renal disease. We randomized 129 maintenance hemodialysis patients to placebo (n=51) or... 
hemodialysis | mineralocorticoid blockade | multiple dosage | randomized controlled trial | HEART-FAILURE | UROLOGY & NEPHROLOGY | CHRONIC KIDNEY-DISEASE | EPLERENONE | BLOCKER | LEFT-VENTRICULAR FUNCTION
Journal Article
by Lenglet, T and Lacomblez, L and Abitbol, J. L and Ludolph, A and Mora, J. S and Robberecht, W and Shaw, P. J and Pruss, R. M and Cuvier, V and Meininger, V and Meininger, Vincent and Lacomblez, Pr Lucette and Salachas, François and Bruneteau, Gaëlle and Pradat, Pierre‐François and Lenglet, Timothée and Lebouteux, Marie and Pibiri, Vanessa and Pouget, Jean and Verschueren, Annie and Campana‐Salort, Emmanuelle and Attarian, Sharam and Couratier, Philippe and Nicolaud, Blerta and Lautrette, Géraldine and Camu, William and Morales, Raoul and Pageot, Nicolas and Desnuelle, Claude and Soriani, Marie‐Hélène and Delmont, Emilien and Destee, Alain and Danel‐Brunaud, Véronique and Devos, David and Vandenberghe, Nadia and Broussolle, Emmanuel and Vial, Christophe and Díaz, Rubén Martires Blanco and Bouhour, Françoise and Mora Pardina, Jesús S and Chaverri, Delia and Mascías, Javier and Hernández, María and Marín, Saul and Salas, Teresa and Moran, Yolanda and Robberecht, Wim and Damme, Philip and Demeestere, Jelle and Al‐Chalabi, Ammar and Leigh, Nigel and Guevara, Carlos and Dimitrov, Nikolay and Wijesekera, Lokesh and Shaw, Pamela and McDermott, Christopher J and Rafiq, Muhammad and Ludolph, Albert and Dorst, Johannes and Waibel, Stefan and Weiland, Ulriche and Hendrich, Corinna and Dengler, Reinhardt and Petri, Suzanne and Kollewe, Katja Maureen and Schmalbach, Sonja and Cordes, Anna‐Lena and Rath, Klaus and Bonzel, Linda and Bolat, Seza and Meyer, Thomas and Maier, André and Dullinger, Jörn and Linke, Peter and Holm, Teresa and Borisow, Nadja and Zierz, Stephan and Hanisch, Frank and Mitotarget Study Grp and Mitotarget study group and the Mitotarget study group
European Journal of Neurology, ISSN 1351-5101, 03/2014, Volume 21, Issue 3, pp. 529 - 536
Journal Article
Journal Article