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Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 11763 - 14
Vascular endothelial growth factor (VEGF) is a key mediator in the development and progression of choroidal neovascularization (CNV) in patients with wet... 
RIBOZYMES | SAFETY | INJECTION | MULTIDISCIPLINARY SCIENCES | RANDOMIZED CLINICAL-TRIAL | MACULAR DEGENERATION | ADENOASSOCIATED VECTORS | CHOROIDAL NEOVASCULARIZATION | EXPRESSION | AGE | SFLT-1 | Dietary supplements | Retina | Injection | Patients | Vascularization | Acuity | Macular degeneration | Atrophy | Overexpression | Degeneration | Supplementation | Gene therapy | Vascular endothelial growth factor | Age
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 09/2011, Volume 52, Issue 10, pp. 7340 - 7346
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1715, pp. 19 - 31
Over the past two decades recombinant adeno-associated virus (rAAV) vectors have emerged as the gold standard for transferring genetic material to cells of the... 
Virus vector | Retina | Purification | Manufacture | Gene therapy | AAV | Dependovirus - genetics | Gene Transfer Techniques | Retina - metabolism | Dependovirus - isolation & purification | Plasmids | Humans | HEK293 Cells | Genetic Vectors | Genetic Therapy - methods | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 3, pp. 1101 - 1106
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 12/2017, Volume 58, Issue 14, pp. 6429 - 6439
PURPOSE. Effective intravitreal gene delivery to cells of the central retina (i.e., photoreceptors) would be of substantial benefit for treating patients with... 
Adeno-associated virus | Intravitreal injection | Gene therapy | Capsid mutation | CLINICAL-TRIAL | ADENOASSOCIATED VIRUS | AAV2 VECTORS | SAFETY | gene therapy | adeno-associated virus | capsid mutation | intravitreal injection | DEGENERATION | HIGH-EFFICIENCY TRANSDUCTION | SEROTYPE VECTORS | OPHTHALMOLOGY | GENE-THERAPY | CONGENITAL AMAUROSIS | DYSTROPHIES | Index Medicus | Retina
Journal Article
Journal Article
Journal Article
The American Journal of Pathology, ISSN 0002-9440, 02/2019, Volume 189, Issue 2, pp. 320 - 338
Farber disease (FD) is a debilitating lysosomal storage disorder characterized by severe inflammation and neurodegeneration. FD is caused by mutations in the... 
INHIBITION | LIPOGRANULOMATOSIS | BIOSYNTHESIS | MOUSE MODEL | SPHINGOSINE-1-PHOSPHATE | FARBERS DISEASE | DYSPLASIA | RETINA | EXPERIMENTAL AUTOIMMUNE UVEORETINITIS | PATHOLOGY | FINGOLIMOD FTY720
Journal Article
Journal Article
Cell reports, ISSN 2211-1247, 06/2019, Volume 27, Issue 11, pp. 3107 - 3116.e3
Throughout the CNS, interactions between pre- and postsynaptic adhesion molecules establish normal synaptic structure and function. Leucine-rich repeat (LRR)... 
Journal Article
Investigative Opthalmology & Visual Science, ISSN 1552-5783, 09/2011, Volume 52, Issue 10, p. 7340
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e60361 - e60361
Journal Article