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1. Full Text Pharmacokinetic issues for antibiotics in the critically ill patient
by Roberts, Jason A and Lipman, Jeffrey
Critical care medicine, ISSN 0090-3493, 03/2009, Volume 37, Issue 3, pp. 840 - 851
Dosing | Antibiotic | Pharmacodynamics | Pharmacokinetics | Critically ill | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | Intensive care medicine | Clinical death. Palliative care. Organ gift and preservation | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Critical Illness | Anti-Bacterial Agents - therapeutic use | Sepsis - drug therapy | Anti-Bacterial Agents - classification | Humans | Anti-Bacterial Agents - pharmacokinetics | Index Medicus | Abridged Index Medicus
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2. Full Text The effect of pathophysiology on pharmacokinetics in the critically ill patient — Concepts appraised by the example of antimicrobial agents
by Blot, Stijn I and Pea, Federico and Lipman, Jeffrey
Advanced drug delivery reviews, ISSN 0169-409X, 11/2014, Volume 77, pp. 3 - 11
Organ failure | Pharmacodynamics | Acute kidney injury | Hepatic failure | Antimicrobial agents | Sepsis | Pharmacokinetics | Intensive care unit | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Humans | Critical Illness | Drug Monitoring - methods | Sepsis - physiopathology | Acute Kidney Injury - physiopathology | Tissue Distribution | Sepsis - drug therapy | Anti-Infective Agents - administration & dosage | Anti-Infective Agents - chemistry | Anti-Infective Agents - pharmacokinetics | Multiple Organ Failure - etiology | Hydrophobic and Hydrophilic Interactions | Multiple Organ Failure - physiopathology | Drugs | Anti-infective agents | Drug delivery systems | Vehicles | Protein binding | Index Medicus
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3. Full Text Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions
by Roberts, Jason A, Prof and Abdul-Aziz, Mohd H, BPharm and Lipman, Jeffrey, Prof and Mouton, Johan W, Prof and Vinks, Alexander A, Prof and Felton, Timothy W, Dr and Hope, William W, Prof and Farkas, Andras, Dr and Neely, Michael N, MD and Schentag, Jerome J, Dr and Drusano, George, Prof and Frey, Otto R, Dr and Theuretzbacher, Ursula, Dr and Kuti, Joseph L, Dr and on behalf of The International Society of Anti-Infective Pharmacology and the Pharmacokinetics and Pharmacodynamics Study Group of the European Society of Clinical Microbiology and Infectious Diseases and European Soc Clinical Microbiology and Int Soc Anti-Infective Pharmacolog and International Society of Anti-Infective Pharmacology and the Pharmacokinetics and Pharmacodynamics Study Group of the European Society of Clinical Microbiology and Infectious Diseases
The Lancet infectious diseases, ISSN 1473-3099, 2014, Volume 14, Issue 6, pp. 498 - 509
Infectious Disease | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Biological and medical sciences | Medical sciences | Antibacterial agents | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Microbial Sensitivity Tests | Drug Dosage Calculations | Precision Medicine - standards | Humans | Anti-Bacterial Agents - pharmacokinetics | Critical Illness - therapy | Anti-Bacterial Agents - administration & dosage | Precision Medicine - methods | Antibiotics | Healthcare industry software | Proteins | Intensive care | Fluids | Linux | Mortality | Sepsis | Regression analysis | Drug dosages | Index Medicus
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4. Full Text Clinical implications of antibiotic pharmacokinetic principles in the critically ill
by Udy, Andrew A and Roberts, Jason A and Lipman, Jeffrey
Intensive care medicine, ISSN 0342-4642, 12/2013, Volume 39, Issue 12, pp. 2070 - 2082
Pediatrics | Dosing | Critical illness | Pain Medicine | Emergency Medicine | Pneumology/Respiratory System | Medicine & Public Health | Antibiotics | Intensive / Critical Care Medicine | Anesthesiology | Pharmacokinetics | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Critical Illness - therapy | Drug Dosage Calculations | Anti-Bacterial Agents - administration & dosage | Humans | Anti-Bacterial Agents - pharmacokinetics | Drug metabolism | Physiological aspects | Care and treatment | Critically ill | Patient outcomes | Index Medicus
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5. The clinical relevance of plasma protein binding changes
by Roberts, Jason A and Pea, Federico and Lipman, Jeffrey
Clinical pharmacokinetics, ISSN 0312-5963, 01/2013, Volume 52, Issue 1, pp. 1 - 8
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Kidney - metabolism | Humans | Anti-Bacterial Agents - pharmacokinetics | Metabolic Clearance Rate | Blood Proteins - metabolism | Body Temperature | Drug Monitoring | Pharmacokinetics | Hydrogen-Ion Concentration | Kidney Function Tests | Protein Binding - physiology | Index Medicus
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6. Augmented renal clearance: Implications for antibacterial dosing in the critically Ill
by Udy, Andrew A and Roberts, Jason A and Boots, Robert J and Paterson, David L and Lipmanl, Jeffrey
Clinical pharmacokinetics, ISSN 0312-5963, 2010, Volume 49, Issue 1, pp. 1 - 16
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Dose-Response Relationship, Drug | Kidney - metabolism | Animals | Humans | Anti-Bacterial Agents - pharmacokinetics | Critical Illness | Practice Patterns, Physicians | Drug Monitoring - methods | Anti-Bacterial Agents - administration & dosage | Kidney Function Tests
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