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1. Full Text Rapid assessment with physical examination in dyspnoeic cats: the RAPID CAT study
by Dickson, D and Little, C. J. L and Harris, J and Rishniw, M
Journal of Small Animal Practice, ISSN 0022-4510, 02/2018, Volume 59, Issue 2, pp. 75 - 84
Objectives To determine the underlying disease prevalence in acute feline dyspnoea and to examine whether historical and clinical examination findings can... 
POPULATION | VETERINARY SCIENCES | NONCARDIAC CAUSES | CONGESTIVE-HEART-FAILURE | DISEASE | DOGS | Physical diagnosis | Cats | Heart beat | Periodic health examinations | Analysis | Training | Heart rate | Tachycardia | Dyspnea | Diagnosis | Respiration | Heart diseases | Cough | Hypothermia
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2. Full Text Lack of correlation between canine heart rate and body size in veterinary clinical practice
by Ferasin, L and Ferasin, H and Little, C. J. L
Journal of Small Animal Practice, ISSN 0022-4510, 08/2010, Volume 51, Issue 8, pp. 412 - 418
Objectives: An association between heart rate (HR) and bodyweight has been reported in dogs and it is common belief that small breeds of dog exhibit higher HR... 
SURFACE AREA | ELECTROCARDIOGRAM | CATS | TEMPERATURE | DOGS | GENDER | VETERINARY SCIENCES | Animals | Prospective Studies | Age Factors | Dogs - physiology | Body Size - physiology | Sex Factors | Heart Rate - physiology | Female | Male | Electrocardiography - veterinary | Retrospective Studies | Electrocardiography | Heart beat | Consulting services | Electrocardiogram | Dogs
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3. Full Text Effect of Pimobendan or Benazepril Hydrochloride on Survival Times in Dogs with Congestive Heart Failure Caused by Naturally Occurring Myxomatous Mitral Valve Disease: The QUEST Study
by Häggström, J and Boswood, A and O'Grady, M and Jöns, O and Smith, S and Swift, S and Borgarelli, M and Gavaghan, B and Kresken, J.‐G and Patteson, M and Åblad, B and Bussadori, C.M and Glaus, T and Kovačević, A and Rapp, M and Santilli, R.A and Tidholm, A and Eriksson, A and Belanger, M.C and Deinert, M and Little, C.J.L and Kvart, C and French, A and Rønn‐Landbo, M and Wess, G and Eggertsdottir, A.V and O'Sullivan, M.L and Schneider, M and Lombard, C.W and Dukes‐McEwan, J and Willis, R and Louvet, A and DiFruscia, R and Sveriges lantbruksuniversitet
Journal of Veterinary Internal Medicine, ISSN 0891-6640, 09/2008, Volume 22, Issue 5, pp. 1124 - 1135
Background: Myxomatous mitral valve disease (MMVD) continues to be an important cause of morbidity and mortality in geriatric dogs despite conventional... 
Mitral regurgitation | Therapy | Mortality | Canine | TRIALS | EFFICACY | ATRIAL | mitral regurgitation | therapy | INSUFFICIENCY | ANGIOTENSIN-ALDOSTERONE SYSTEM | canine | KING CHARLES SPANIELS | REGURGITATION | mortality | PROLAPSE | VETERINARY SCIENCES | ENALAPRIL | EPIDEMIOLOGY | Heart Failure - complications | Multivariate Analysis | Benzazepines - adverse effects | Proportional Hazards Models | Male | Mitral Valve Insufficiency - veterinary | Cardiotonic Agents - therapeutic use | Animals | Dog Diseases - drug therapy | Benzazepines - therapeutic use | Cardiotonic Agents - adverse effects | Dogs | Mitral Valve Insufficiency - complications | Female | Heart Failure - veterinary | Mitral Valve Insufficiency - drug therapy | Pyridazines - adverse effects | Pyridazines - therapeutic use | Heart Failure - mortality | Index Medicus | Veterinary Science | Veterinärmedicin | Animal and Dairy Science | Husdjursvetenskap
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4. Full Text Heart rate turbulence after ventricular premature beats in healthy Doberman pinschers and those with dilated cardiomyopathy
by Harris, J.D and Little, C.J.L and Dennis, J.M and Patteson, M.W
Journal of Veterinary Cardiology, ISSN 1760-2734, 10/2017, Volume 19, Issue 5, pp. 421 - 432
To describe the measurement of heart rate turbulence (HRT) after ventricular premature beats and compare HRT in healthy Doberman pinschers and those with... 
Holter monitoring | Congestive heart failure | Autonomic nervous system | Heart rate variability | Canine | MORTALITY | RATE-VARIABILITY | SUDDEN-DEATH | CARDIAC VAGAL TONE | Hotter monitoring | FAILURE | DOGS | ACUTE MYOCARDIAL-INFARCTION | VETERINARY SCIENCES | PROGNOSTIC-SIGNIFICANCE | ECHOCARDIOGRAPHIC EVIDENCE | AGE | Heart Rate | Prospective Studies | Male | Case-Control Studies | Electrocardiography, Ambulatory - veterinary | Animals | Cardiomyopathy, Dilated - physiopathology | Dog Diseases - physiopathology | Pedigree | Ventricular Premature Complexes - physiopathology | Dogs | Ventricular Premature Complexes - diagnosis | Cardiomyopathy, Dilated - diagnosis | Female | Retrospective Studies | Dog Diseases - diagnosis | Cardiomyopathy, Dilated - veterinary | Ventricular Premature Complexes - veterinary | Heart | Heart beat | Arrhythmia | Cardiomyopathy, Dilated | Medical records | Heart diseases
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5. Full Text Purring in cats during auscultation: how common is it, and can we stop it?
by Little, C. J. L and Ferasin, L and Ferasin, H and Holmes, M. A
Journal of Small Animal Practice, ISSN 0022-4510, 01/2014, Volume 55, Issue 1, pp. 33 - 38
OBJECTIVES When cats purr during examination it is difficult to perform auscultation. The objective of this study was to determine the prevalence of purring in... 
VETERINARY SCIENCES | PREVALENCE | HEALTHY CATS | DISEASE | Behavior, Animal | Animals | Auscultation - veterinary | Auscultation - methods | Cat Diseases - diagnosis | Cats - psychology | Female | Male | Cats | Running | Sound | Automobile industry
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6. Full Text Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Myxomatous Mitral Valve Disease Receiving Pimobendan or Benazepril: The QUEST Study
by Häggström, J and Boswood, A and O'Grady, M and Jöns, O and Smith, S and Swift, S and Borgarelli, M and Gavaghan, B and Kresken, J.‐G and Patteson, M and Åblad, B and Bussadori, C.M and Glaus, T and Kovačević, A and Rapp, M and Santilli, R.A and Tidholm, A and Eriksson, A and Belanger, M.C and Deinert, M and Little, C.J.L and Kvart, C and French, A and Rønn‐Landbo, M and Wess, G and Eggertsdottir, A and Lynne O'Sullivan, M and Schneider, M and Lombard, C.W and Dukes‐McEwan, J and Willis, R and Louvet, A and DiFruscia, R and Sveriges lantbruksuniversitet
Journal of Veterinary Internal Medicine, ISSN 0891-6640, 11/2013, Volume 27, Issue 6, pp. 1441 - 1451
Background Myxomatous mitral valve disease (MMVD) is an important cause of morbidity and mortality in dogs. Objectives To compare, throughout the period of... 
Mitral regurgitation | Therapy | Mortality | Canine | SURVIVAL | EFFICACY | DILATED CARDIOMYOPATHY | BODY-TEMPERATURE | DOBERMAN-PINSCHERS | REGURGITATION | HYPONATREMIA | VETERINARY SCIENCES | CONGESTIVE-HEART-FAILURE | ENALAPRIL | Single-Blind Method | Echocardiography - veterinary | Prospective Studies | Heart Failure - physiopathology | Male | Pyridazines - pharmacology | Body Temperature - physiology | Mitral Valve - physiopathology | Cardiotonic Agents - therapeutic use | Dog Diseases - drug therapy | Hematocrit - veterinary | Dog Diseases - physiopathology | Mitral Valve - drug effects | Heart Valve Diseases - veterinary | Heart Rate - physiology | Female | Blood Pressure - physiology | Heart Failure - diagnostic imaging | Pyridazines - therapeutic use | Dog Diseases - diagnostic imaging | Heart Valve Diseases - physiopathology | Kaplan-Meier Estimate | Benzazepines - pharmacology | Cardiotonic Agents - pharmacology | Sodium - blood | Heart Failure - drug therapy | Animals | Mitral Valve - diagnostic imaging | Benzazepines - therapeutic use | Dogs | Quality of Life | Heart Failure - veterinary | Heart Valve Diseases - drug therapy | Longitudinal Studies | Heart Valve Diseases - diagnostic imaging | Heart failure | Heart valve diseases | Medical research | Medicine, Experimental | Benazepril | Other Veterinary Science | Annan veterinärmedicin
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7. Erratum: Heart failure in two West Highland white terriers caused by congenital angiomatous cardiac anomaly (Veterinary Record (2007) 161, (161-164))
by Kovačević, A and Little, C.J.L and Lombard, C.W and Schöniger, S
Veterinary Record, ISSN 0042-4900, 08/2007, Volume 161, Issue 7, p. 225
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8. Full Text Heart failure is common in diabetic cats: findings from a retrospective case‐controlled study in first‐opinion practice
by Little, C. J. L and Gettinby, G
Journal of Small Animal Practice, ISSN 0022-4510, 01/2008, Volume 49, Issue 1, pp. 17 - 25
Objectives: To study the prognosis and cause of death in cats with diabetes mellitus. Methods: Twenty consecutive cases of feline diabetes mellitus diagnosed... 
MORTALITY | VETERINARY SCIENCES | MELLITUS | HEALTHY CATS | DISEASE | Cats | Prevalence | Prognosis | Follow-Up Studies | Diabetes Complications - veterinary | Risk Factors | Male | Survival Rate | Cat Diseases - mortality | Case-Control Studies | Animals | Diabetes Mellitus - epidemiology | Female | Cat Diseases - epidemiology | Heart Failure - veterinary | Retrospective Studies | Diabetes Mellitus - veterinary | Diabetes Mellitus - mortality | Heart Failure - epidemiology | Heart Failure - mortality | Heart failure | Diabetics | Diabetes | Insulin | Analysis
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9. Full Text Hypoglycaemic bradycardia and circulatory collapse in a dog and a cat
by Little, C. J. L
Journal of Small Animal Practice, ISSN 0022-4510, 09/2005, Volume 46, Issue 9, pp. 445 - 448
Hypoglycaemia was accompanied by sinus bradycardia and circulatory collapse in a dog and a cat. In each case, when the hypoglycaemia was corrected by... 
MATERNAL HYPOGLYCEMIA | RESPONSES | PROPRANOLOL | HYPOGLYCAEMIA | VETERINARY SCIENCES | FETAL BRADYCARDIA | MANIFESTATIONS | Hypoglycemia - diagnosis | Cats | Bradycardia - diagnosis | Shock - veterinary | Cat Diseases - diagnosis | Male | Treatment Outcome | Electrocardiography - veterinary | Hypoglycemia - drug therapy | Shock - etiology | Shock - diagnosis | Animals | Bradycardia - veterinary | Bradycardia - etiology | Dogs | Hypoglycemia - complications | Female | Glucose - therapeutic use | Dog Diseases - diagnosis | Hypoglycemia - veterinary
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10. Heart failure in two West Highland white terriers caused by congenital angiomatous cardiac anomaly
by Kovačević, A and Little, C.J.L and Lombard, C.W and Schöniger, S
Veterinary Record, ISSN 0042-4900, 08/2007, Volume 161, Issue 5, pp. 161 - 164
The paper describes the clinical and pathological characteristics of an unusual cystic congenital cardiac anomaly that caused clinical signs of congestive... 
VETERINARY SCIENCES | CYSTS | DOGS | M-MODE ECHOCARDIOGRAPHY | Echocardiography - veterinary | Heart Failure - complications | Diagnosis, Differential | Autopsy - veterinary | Heart Defects, Congenital - veterinary | Male | Dog Diseases - pathology | Animals | Heart Defects, Congenital - complications | Pedigree | Dogs | Heart Defects, Congenital - diagnosis | Heart Failure - diagnosis | Heart Failure - veterinary | Dog Diseases - diagnosis | Dog Diseases - diagnostic imaging
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11. Non-invasive real-time measurements of cardiac vagal tone in dogs with cardiac disease
by Little, C.J.L and Julu, P.O.O and Hansen, S and Reid, S.W.J
Veterinary Record, ISSN 0042-4900, 01/2005, Volume 156, Issue 4, pp. 101 - 105
In dogs with spontaneous heart disease, an electronically generated measurement of cardiac vagal tone, the cardiac index of parasympathetic activity, was a... 
MORTALITY | BAROREFLEX SENSITIVITY | HEART-RATE-VARIABILITY | ACUTE MYOCARDIAL-INFARCTION | VETERINARY SCIENCES | MODEL | FAILURE | Heart Conduction System - pathology | Severity of Illness Index | Heart Rate | Heart Diseases - physiopathology | Risk Factors | Logistic Models | Male | Case-Control Studies | Vagus Nerve - pathology | Parasympathetic Nervous System - pathology | Vagus Nerve - physiology | Animals | Dog Diseases - physiopathology | Heart Conduction System - physiology | Sensitivity and Specificity | Dogs | Female | Parasympathetic Nervous System - physiology
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12. Full Text Real-time measurement of cardiac vagal tone in conscious dogs
by C. J. L. Little and P. O. O. Julu and S. Hansen and S. W. J. Reid
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/1999, Volume 276, Issue 2, pp. 758 - 765
Rapid changes in heart rate are caused by changes in parasympathetic tone. The NeuroScope is an electronic device designed to offer an objective real-time... 
Atropine | NeuroScope | Parasympathetic tone | Autonomic nervous system | Heart rate variability | CHRONIC HEART-FAILURE | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | autonomic nervous system | STIMULATION | PARASYMPATHETIC ACTIVITY | HUMANS | parasympathetic tone | BLOOD-PRESSURE | BARORECEPTOR | VARIABILITY | heart rate variability | PERIPHERAL VASCULAR DISEASE | SPECTRAL-ANALYSIS | atropine | RESPIRATORY SINUS ARRHYTHMIA | Vagus Nerve - drug effects | Atropine - pharmacology | Male | Heart Conduction System - drug effects | Dose-Response Relationship, Drug | Heart Rate - drug effects | Vagus Nerve - physiology | Animals | Heart Conduction System - physiology | Parasympathetic Nervous System - drug effects | Dogs | Heart Rate - physiology | Computer Systems | Parasympathetic Nervous System - physiology | Physiological aspects | Heart beat | Research | Cardiovascular research
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13. Full Text Factors affecting accidental extubations in neonatal and pediatric intensive care patients
by LITTLE, LINDA A and KOENIG, JOHN C and NEWTH, CHRISTOPHER J. L
Critical Care Medicine, ISSN 0090-3493, 02/1990, Volume 18, Issue 2, pp. 163 - 165
All patients intubated in the neonatal (NICU) and pediatric (PICU) ICUs over a 3-yr period were evaluated prospectively to determine the incidence of... 
CRITICAL CARE | Prospective Studies | Intensive Care Units, Neonatal | Humans | Risk Factors | Adolescent | Child, Preschool | Critical Care | Infant | Intensive Care Units, Pediatric | Intubation, Intratracheal | Child | Infant, Newborn
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14. Hep atop athy and dermatitis in a dog associated with the ingestion of mycotoxins
by Little, C.J.L and McNeil, P.E and Robb, J
Journal of Small Animal Practice, ISSN 0022-4510, 1991, Volume 32, Issue 1, pp. 23 - 26
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15. Investigation of heart rate variability in a dog with upper respiratory tract obstruction
by Little, C.J and Little, C.J.L and Julu, P.O.O and Julu, P.O
Journal of Small Animal Practice, ISSN 0022-4510, 1995, Volume 36, Issue 11, pp. 502 - 506
An eight-year-old bull mastiff presented with respiratory obstruction caused by a tumour dorsolateral to the larynx. Removal of the tumour was attempted but... 
CANINE LARYNGEAL PARALYSIS | UPPER AIRWAY-OBSTRUCTION | VETERINARY SCIENCES | CARDIAC CONTROL | Airway Obstruction - etiology | Laryngeal Neoplasms - veterinary | Airway Obstruction - physiopathology | Electrocardiography - veterinary | Carcinoma - veterinary | Laryngeal Neoplasms - pathology | Animals | Carcinoma - complications | Dog Diseases - physiopathology | Dog Diseases - etiology | Dogs | Heart Rate - physiology | Female | Parasympathetic Nervous System - physiopathology | Carcinoma - pathology | Dog Diseases - diagnosis | Airway Obstruction - veterinary | Laryngeal Neoplasms - complications | Heart - innervation
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16. Trimethoprim-sulphonamide hypersensitivity in dogs
by Little, C.J.L and Carmichael, S
Veterinary Record, ISSN 0042-4900, 1990, Volume 127, Issue 18, pp. 459 - 460
Animals | Drug Hypersensitivity - veterinary | Trimethoprim - adverse effects | Joint Diseases - veterinary | Dogs | Sulfonamides - adverse effects | Male | Dog Diseases - chemically induced | Joint Diseases - chemically induced
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17. The surgical anatomy of the feline bulla tympanica
by LITTLE, C.J.L and LANE, J.G
Journal of Small Animal Practice, ISSN 0022-4510, 1986, Volume 27, Issue 6, pp. 371 - 378
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18. Surgery of the canine external auditory meatus: a review of failures
by LANE, J.G and LITTLE, C.J.L
Journal of Small Animal Practice, ISSN 0022-4510, 1986, Volume 27, Issue 4, pp. 247 - 254
VETERINARY SCIENCES
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19. Full Text One‐dose antibiotic prophylaxis against wound infection after appendicectomy: A randomized trial of clindamycin, cefazolin sodium and a placebo
by Donovan, I. A and Ellis, D and Gatehouse, D and Little, G and Grimley, R and Armistead, S and Keighley, M. R. B and Strachan, C. J. L
British Journal of Surgery, ISSN 0007-1323, 03/1979, Volume 66, Issue 3, pp. 193 - 196
Two hundred and fifty patients were admitted to a prospective randomized trial of single dosage prophylaxis against wound infection after appendicectomy. There... 
Appendectomy - adverse effects | Cefazolin - therapeutic use | Humans | Postoperative Period | Clinical Trials as Topic | Cefazolin - administration & dosage | Random Allocation | Clindamycin - therapeutic use | Cephalosporins - therapeutic use | Surgical Wound Infection - prevention & control | Clindamycin - administration & dosage | Placebos | Adult | Aged | Surgical Wound Infection - microbiology
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20. Wirkung von Pimobendan oder Benazeprilhydrochlorid auf die Überlebenszeit von Hunden mit kongestiver Herzinsuffizienz durch natürlich auftretende myxomatöse Mitralklappenerkrankung: Die QUEST-Studie
by Häggström, J and Boswood, A and O'Grady, M and Jöns, O and Smith, S and Swift, S and Borgarelli, M and Gavaghan, B and Kresken, J.-G and Patteson, M and Åblad, B and Bussadori, C.M and Glaus, T and Kovačević, A and Rapp, M and Santllli, R.A and Tidholm, A and Eriksson, A and Belanger, M.C and Deinert, M and Little, C.J.L and Kvart, C and French, A and Rønn-Landbo, M and Wess, G and Eggertsdottir, A.V and O'Sullivan, M.L and Schneider, M and Lombard, C.W and Dukes-McEwan, J and Willis, R and Louvet, A and DiFruscia, R
12/2008, Volume 53, Issue 12
Therapy | Mortality | Mitral regurgitation | Canine
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