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by Zou, LF and Yu, KH and Fan, Y and Cao, SX and Liu, SM and Shi, LR and Li, L and Yuan, HL and Yang, RN and Yi, ZH and Gao, Y and Li, GL and Greffrath, W and Treede, RD and Li, M and Xu, H and Zhang, CP and Liang, SD
ACS CHEMICAL NEUROSCIENCE, ISSN 1948-7193, 03/2019, Volume 10, Issue 3, pp. 1318 - 1325
Activation of satellite glial cells (SGCs) in the dorsal root ganglia (DRG) is involved in mechanical and thermal hyperalgesia. The upregulated P2Y(12)... 
SYSTEM | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | dorsal root ganglia | NEUROSCIENCES | SATELLITE GLIAL-CELLS | neuropathic pain | guanfu base A | MICROGLIA | P2Y receptor | SENSORY GANGLIA | UP-REGULATION | satellite glial cells
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 03/2019, Volume 10, Issue 3, pp. 1318 - 1325
Journal Article
Drug Delivery and Translational Research, ISSN 2190-393X, 10/2018, Volume 8, Issue 5, pp. 1471 - 1482
Guanfu base A·HCl (GFA·HCl) solution, approved by the China Food and Drug Administration (CFDA) in 2005, has been used in the treatment of arrhythmia. However,... 
Anti-arrhythmia effect | Heart specificity | Guanfu base A | Biomedicine | Pharmaceutical Sciences/Technology | Target drug delivery | Solid nanolipids | MEDICINE, RESEARCH & EXPERIMENTAL | LIPID NANOPARTICLES | CLINICAL DEVELOPMENT | FORMULATION | ACONITUM-COREANUM | PHARMACOKINETICS | LIPOSOME | DISEASE | PHARMACOLOGY & PHARMACY | DRUG-DELIVERY SYSTEMS
Journal Article
ACS Chemical Neuroscience, 03/2019, Volume 10, Issue 3, pp. 1318 - 1325
Activation of satellite glial cells (SGCs) in the dorsal root ganglia (DRG) is involved in mechanical and thermal hyperalgesia. The upregulated P2Y receptor... 
neuropathic pain | guanfu base A | receptor | P2Y | dorsal root ganglia | satellite glial cells
Journal Article
Journal of China Pharmaceutical University, ISSN 1000-5048, 04/2015, Volume 46, Issue 2, pp. 235 - 241
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 05/2012, Volume 22, Issue 9, pp. 3100 - 3103
Guanfu alcohol-amine (GFAA) was regioselectively converted to Guanfu base G (GFG) by Novozym 435 in non-aqueous phase. Lipase-catalyzed acylation of Guanfu... 
Guanfu base G | Vinyl acetate | Lipases | Acylation | ENZYMATIC ACYLATION | CHEMISTRY, MEDICINAL | ESTERIFICATION | CHEMISTRY, ORGANIC | MEDIA | Vinyl Compounds - chemistry | Biocatalysis | Heterocyclic Compounds, 4 or More Rings - chemical synthesis | Molecular Structure | Lipase - metabolism | Methods | Methanol | Lipase
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2005, Volume 28, Issue 8, pp. 1363 - 1365
A liquid chromatographic-mass spectrometric (LC-MS) method was developed and validated for determination of guanfu base I (GFI), and the pharmacokinetics of... 
pharmacokinetics | LC-MS | guanfu base I | Pharmacokinetics | Guanfu base I | Reproducibility of Results | Animals | Spectrometry, Mass, Electrospray Ionization | Heterocyclic Compounds, 4 or More Rings - pharmacokinetics | Chromatography, Liquid | Half-Life | Rats | Male | Heterocyclic Compounds, 4 or More Rings - blood | Rats, Sprague-Dawley
Journal Article
by Li, XT and Wang, GJ and Wang, SJ and Sun, JG and Liu, JH
BIOLOGICAL & PHARMACEUTICAL BULLETIN, ISSN 0918-6158, 08/2005, Volume 28, Issue 8, pp. 1363 - 1365
A liquid chromatographic-mass spectrometric (LC-MS) method was developed and validated for determination of guanfu base I (GFI), and the pharmacokinetics of... 
LC-MS | guanfu base 1 | pharmacokinetics | PHARMACOLOGY & PHARMACY
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 08/2005, Volume 28, Issue 8, p. 1363
  A liquid chromatographic-mass spectrometric (LC-MS) method was developed and validated for determination of guanfu base I (GFI), and the pharmacokinetics of... 
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2005, Volume 28, Issue 8, pp. 1363 - 1365
A liquid chromatographic-mass spectrometric (LC-MS) method was developed and validated for determination of guanfu base I (GFI), and the pharmacokinetics of... 
Journal Article
Journal of China Pharmaceutical University, ISSN 1000-5048, 04/2005, Volume 36, Issue 2, pp. 142 - 145
Journal Article
Zhonghua xin xue guan bing za zhi [Chinese journal of cardiovascular diseases], ISSN 0253-3758, 2006, Volume 34, Issue 4, pp. 329 - 332
Journal Article
Zhonghua xin xue guan bing za zhi, ISSN 0253-3758, 04/2006, Volume 34, Issue 4, p. 329
To investigate the effect and safety of intravenous Guanfu Base A hydrochloride (GFA) in the treatment of ventricular arrhythmias. Patients without severe... 
Double-Blind Method | Tachycardia, Ventricular - drug therapy | Humans | Middle Aged | Male | Anti-Arrhythmia Agents - therapeutic use | Young Adult | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Ventricular Premature Complexes - drug therapy | Adolescent | Adult | Female | Phytotherapy
Journal Article
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